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ONTOLOGY REPORT - ANNOTATIONS


Term:proline metabolic process
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Accession:GO:0006560 term browser browse the term
Definition:The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
Synonyms:exact_synonym: proline metabolism



show annotations for term's descendants           Sort by:
 
arginine catabolic process to proline via ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OAT ornithine aminotransferase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr28:33,763,661...33,788,817
Ensembl chr28:33,758,473...33,788,759
JBrowse link
L-proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH18A1 aldehyde dehydrogenase 18 family member A1 involved_in IEA UniProt GO_REF:0000041 NCBI chr28:9,101,578...9,148,063
Ensembl chr28:9,102,282...9,147,992
JBrowse link
G OAT ornithine aminotransferase involved_in IEA UniProt GO_REF:0000041 NCBI chr28:33,763,661...33,788,817
Ensembl chr28:33,758,473...33,788,759
JBrowse link
G PYCR2 pyrroline-5-carboxylate reductase 2 involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr 7:38,902,705...38,905,924 JBrowse link
G PYCR3 pyrroline-5-carboxylate reductase 3 involved_in ISO (PMID:23024808) UniProt PMID:23024808 NCBI chr13:37,259,139...37,264,337
Ensembl chr13:37,259,139...37,264,337
JBrowse link
proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH18A1 aldehyde dehydrogenase 18 family member A1 involved_in ISO (PMID:11092761), (PMID:26297558) UniProt PMID:11092761 PMID:26297558 NCBI chr28:9,101,578...9,148,063
Ensembl chr28:9,102,282...9,147,992
JBrowse link
G PYCR1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:16730026) UniProt PMID:16730026 NCBI chr 9:360,353...364,795
Ensembl chr 9:360,376...364,570
JBrowse link
G PYCR2 pyrroline-5-carboxylate reductase 2 involved_in ISO (PMID:23024808) UniProt PMID:23024808 NCBI chr 7:38,902,705...38,905,924 JBrowse link
proline catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAO D-amino acid oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:18,032,663...18,057,277
Ensembl chr26:18,033,392...18,057,238
JBrowse link
proline catabolic process to glutamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH4A1 aldehyde dehydrogenase 4 family member A1 involved_in IEA UniProt GO_REF:0000041 NCBI chr 2:79,688,078...79,712,340
Ensembl chr 2:79,688,086...79,710,540
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13875
    metabolic process 8978
      primary metabolic process 7895
        cellular amino acid metabolic process 219
          alpha-amino acid metabolic process 164
            glutamine family amino acid metabolic process 63
              proline metabolic process 7
                arginine catabolic process to proline + 1
                negative regulation of proline metabolic process + 0
                nopaline catabolic process to proline 0
                octopine catabolic process to proline 0
                ornithine catabolic process via proline 0
                positive regulation of proline metabolic process + 0
                proline biosynthetic process + 5
                proline catabolic process + 2
                regulation of proline metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 13875
    metabolic process 8978
      cellular metabolic process 8168
        organic acid metabolic process 769
          oxoacid metabolic process 744
            carboxylic acid metabolic process 731
              cellular amino acid metabolic process 219
                alpha-amino acid metabolic process 164
                  glutamine family amino acid metabolic process 63
                    proline metabolic process 7
                      arginine catabolic process to proline + 1
                      negative regulation of proline metabolic process + 0
                      nopaline catabolic process to proline 0
                      octopine catabolic process to proline 0
                      ornithine catabolic process via proline 0
                      positive regulation of proline metabolic process + 0
                      proline biosynthetic process + 5
                      proline catabolic process + 2
                      regulation of proline metabolic process + 0
paths to the root