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ONTOLOGY REPORT - ANNOTATIONS


Term:proline metabolic process
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Accession:GO:0006560 term browser browse the term
Definition:The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
Synonyms:exact_synonym: proline metabolism



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arginine catabolic process to proline via ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oat ornithine aminotransferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
L-proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Noxred1 NADP-dependent oxidoreductase domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:106,862,350...106,888,113
Ensembl chr 6:106,862,343...106,884,712
JBrowse link
G Oat ornithine aminotransferase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549
JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr13:92,626,462...92,630,256
Ensembl chr13:92,626,471...92,634,184
JBrowse link
G Pycr3 pyrroline-5-carboxylate reductase 3 involved_in IBA
ISS
ISO
IEA
PMID:21873635
GO_REF:0000024
(PMID:23024808)
GO_REF:0000041
UniProt
RGD
PMID:23024808 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr 7:107,603,543...107,608,831 JBrowse link
proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761 PMID:26297558 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:16730026) RGD PMID:16730026 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549
JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:23024808)
UniProt
RGD
PMID:23024808 GO_REF:0000024 NCBI chr13:92,626,462...92,630,256
Ensembl chr13:92,626,471...92,634,184
JBrowse link
proline catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dao D-amino-acid oxidase involved_in ISO
IBA
IEA
(PMID:16616139)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:16616139 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741
JBrowse link
G Prodh2 proline dehydrogenase 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:85,753,558...85,767,165
Ensembl chr 1:85,753,644...85,767,162
JBrowse link
proline catabolic process to glutamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:151,880,002...151,905,491 JBrowse link
G Iffo2 intermediate filament family orphan 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:151,831,503...151,873,075 JBrowse link
G Prodh1 proline dehydrogenase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305
JBrowse link
G Prodh2 proline dehydrogenase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:85,753,558...85,767,165
Ensembl chr 1:85,753,644...85,767,162
JBrowse link
G Tas1r2 taste 1 receptor member 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:151,909,648...151,925,345 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19391
    metabolic process 11735
      primary metabolic process 10467
        cellular amino acid metabolic process 272
          alpha-amino acid metabolic process 200
            glutamine family amino acid metabolic process 75
              proline metabolic process 12
                arginine catabolic process to proline + 1
                negative regulation of proline metabolic process + 0
                nopaline catabolic process to proline 0
                octopine catabolic process to proline 0
                ornithine catabolic process via proline 0
                positive regulation of proline metabolic process + 0
                proline biosynthetic process + 6
                proline catabolic process + 6
                regulation of proline metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19391
    metabolic process 11735
      cellular metabolic process 10655
        organic acid metabolic process 1008
          oxoacid metabolic process 976
            carboxylic acid metabolic process 957
              cellular amino acid metabolic process 272
                alpha-amino acid metabolic process 200
                  glutamine family amino acid metabolic process 75
                    proline metabolic process 12
                      arginine catabolic process to proline + 1
                      negative regulation of proline metabolic process + 0
                      nopaline catabolic process to proline 0
                      octopine catabolic process to proline 0
                      ornithine catabolic process via proline 0
                      positive regulation of proline metabolic process + 0
                      proline biosynthetic process + 6
                      proline catabolic process + 6
                      regulation of proline metabolic process + 0
paths to the root