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ONTOLOGY REPORT - ANNOTATIONS

Term:S-adenosylmethionine biosynthetic process
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Accession:GO:0006556 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
Synonyms:exact_synonym: S-adenosyl methionine biosynthesis;   S-adenosyl methionine biosynthetic process;   S-adenosylmethionine anabolism;   S-adenosylmethionine biosynthesis;   S-adenosylmethionine formation;   S-adenosylmethionine synthesis;   SAM biosynthetic process
 xref: MetaCyc:SAM-PWY


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S-adenosylmethionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAT1A methionine adenosyltransferase 1A involved_in ISO
IBA
IEA
ISS
IDA
IMP		 (PMID:25075345)
(PMID:10677294)		 RGD
GO_Central
TreeGrafter
ComplexPortal
UniProt
InterPro		 PMID:9202427 PMID:10677294 PMID:10898761 PMID:19497982 PMID:25075345 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 GO_REF:0000114 GO_REF:0000117 GO_REF:0000118 RGD:1359039 RGD:7242770 RGD:7242777 NCBI chr10:80,271,820...80,289,658
Ensembl chr10:80,271,820...80,289,658 		JBrowse link
G MAT2A methionine adenosyltransferase 2A acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA
IDA		 (PMID:12023972)
(PMID:10644686), (PMID:25075345)		 RGD
MGI
GO_Central
TreeGrafter
UniProt
Ensembl
InterPro		 PMID:10644686 PMID:10898761 PMID:12023972 PMID:12029623 PMID:25075345 GO_REF:0000002 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 RGD:7242777 RGD:727376 NCBI chr 2:85,539,168...85,545,281
Ensembl chr 2:85,539,168...85,545,281 		JBrowse link
G MAT2B methionine adenosyltransferase 2 non-catalytic beta subunit involved_in IDA
IEA
IBA		 (PMID:10644686), (PMID:25075345) UniProt
TreeGrafter
GO_Central		 PMID:10644686 PMID:25075345 GO_REF:0000033 GO_REF:0000041 GO_REF:0000118 NCBI chr 5:163,503,064...163,519,354
Ensembl chr 5:163,503,114...163,519,558 		JBrowse link
G METTL16 methyltransferase 16, RNA N6-adenosine acts_upstream_of IDA
IMP		 (PMID:28525753), (PMID:30197297)
(PMID:30197299)		 UniProt PMID:28525753 PMID:30197297 PMID:30197299 NCBI chr17:2,415,715...2,511,888
Ensembl chr17:2,405,562...2,511,891 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19770
    metabolic process 12509
      biosynthetic process 9311
        organic substance biosynthetic process 9244
          S-adenosylmethionine biosynthetic process 4
Path 2
Term Annotations click to browse term
  biological_process 19770
    metabolic process 12509
      cellular metabolic process 11168
        sulfur compound metabolic process 367
          sulfur compound biosynthetic process 179
            S-adenosylmethionine biosynthetic process 4
paths to the root