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ONTOLOGY REPORT - ANNOTATIONS


Term:S-adenosylmethionine biosynthetic process
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Accession:GO:0006556 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
Synonyms:exact_synonym: S-adenosyl methionine biosynthesis;   S-adenosyl methionine biosynthetic process;   S-adenosylmethionine anabolism;   S-adenosylmethionine biosynthesis;   S-adenosylmethionine formation;   S-adenosylmethionine synthesis;   SAM biosynthetic process
 xref: MetaCyc:SAM-PWY



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S-adenosylmethionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mat1a methionine adenosyltransferase 1A involved_in IDA
IEA
ISO
IBA
GO_REF:0000041
(PMID:10677294), (PMID:25075345)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:10677294 PMID:25075345 PMID:9202427 PMID:19497982 PMID:10898761 GO_REF:0000033 GO_REF:0000041, RGD:1359039, RGD:7242770, RGD:7242777 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274
JBrowse link
G Mat2a methionine adenosyltransferase 2A involved_in
acts_upstream_of_or_within
TAS
IDA
ISO
IEA
IBA
(PMID:10644686), (PMID:25075345)
GO_REF:0000041
GO_REF:0000033
(PMID:12023972)
RGD
UniProt
GO_Central
PMID:10644686 PMID:12023972 PMID:25075345 PMID:11099469 PMID:12029623 More... GO_REF:0000033 GO_REF:0000041, RGD:1359040, RGD:727376, RGD:7242777 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Mat2al1 methionine adenosyltransferase 2A like 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr13:26,088,997...26,090,862
Ensembl chr13:26,089,606...26,090,793
JBrowse link
G Mat2b methionine adenosyltransferase 2 non-catalytic beta subunit involved_in IEA
ISO
ISS
IBA
GO_REF:0000041
(PMID:10644686), (PMID:25075345)
GO_REF:0000024
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:10644686 PMID:25075345 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777
JBrowse link
G Mettl16 methyltransferase 16, RNA N6-adenosine acts_upstream_of ISO (PMID:28525753), (PMID:30197297), (PMID:30197299)
(MGI:6199095|PMID:30197299)
RGD PMID:28525753 PMID:30197297 PMID:30197299 MGI:6199095 NCBI chr10:59,640,915...59,697,291
Ensembl chr10:59,640,972...59,687,061
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11720
      biosynthetic process 8355
        organic substance biosynthetic process 8290
          S-adenosylmethionine biosynthetic process 5
Path 2
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11720
      cellular metabolic process 10279
        sulfur compound metabolic process 339
          sulfur compound biosynthetic process 144
            S-adenosylmethionine biosynthetic process 5
paths to the root