S-adenosylmethionine biosynthetic process - Ontology Report

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ONTOLOGY REPORT - ANNOTATIONS	{{ watchLinkText }}

Term:	S-adenosylmethionine biosynthetic process	go back to main search page
Accession:	GO:0006556	browse the term
Definition:	The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
Synonyms:	exact_synonym:	S-adenosyl methionine biosynthesis; S-adenosyl methionine biosynthetic process; S-adenosylmethionine anabolism; S-adenosylmethionine biosynthesis; S-adenosylmethionine formation; S-adenosylmethionine synthesis; SAM biosynthetic process
	xref:	MetaCyc:SAM-PWY

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Rat (4) Mouse (4) Human (4) Chinchilla (4) Bonobo (4) Dog (4) Squirrel (4) Pig (4) Green Monkey (4) Naked Mole-rat (4) All
Genes (4)

S-adenosylmethionine biosynthetic process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Mat1a

methionine adenosyltransferase 1A

involved_in

IDA
ISO
IEA
IBA

(PMID:10677294), (PMID:25075345)
GO_REF:0000041
PMID:21873635

RGD
UniProt

PMID:10677294 PMID:25075345 PMID:9202427 PMID:21873635 PMID:10898761 More...

GO_REF:0000041, RGD:1359039, RGD:13792537, RGD:7242777, RGD:7242770

NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274

Mat2a

methionine adenosyltransferase 2A

acts_upstream_of_or_within
involved_in

TAS
ISO
IEA
IBA
IDA

(MGI:2183618|PMID:12023972)
GO_REF:0000041
PMID:21873635
(PMID:10644686), (PMID:25075345)

RGD
UniProt

PMID:10644686 PMID:12023972 PMID:25075345 PMID:11099469 PMID:21873635 More...

GO_REF:0000041 MGI:2183618, RGD:1359040, RGD:13792537, RGD:727376, RGD:7242777

NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493

Mat2b

methionine adenosyltransferase 2B

involved_in

IBA
IEA
ISO
ISS

PMID:21873635
GO_REF:0000041
(PMID:10644686), (PMID:25075345)
GO_REF:0000024

UniProt
RGD

PMID:10644686 PMID:25075345 PMID:21873635

GO_REF:0000024 GO_REF:0000041, RGD:13792537

NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777

Mettl16

methyltransferase like 16

acts_upstream_of

ISO

(PMID:28525753), (PMID:30197297), (PMID:30197299)
(MGI:6199095|PMID:30197299)

RGD

PMID:28525753 PMID:30197297 PMID:30197299

MGI:6199095

NCBI chr10:59,640,915...59,697,291
Ensembl chr10:59,640,972...59,687,061

Term paths to the root

Path 1
Term	Annotations
biological_process	19497
metabolic process	11824
biosynthetic process	6089
organic substance biosynthetic process	5988
S-adenosylmethionine biosynthetic process	4
Path 2
Term	Annotations
biological_process	19497
metabolic process	11824
cellular metabolic process	10719
sulfur compound metabolic process	329
sulfur compound biosynthetic process	111
S-adenosylmethionine biosynthetic process	4

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Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
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ONTOLOGY REPORT - ANNOTATIONS