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ONTOLOGY REPORT - ANNOTATIONS

Term:methionine metabolic process
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Accession:GO:0006555 term browser browse the term
Definition:The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
Synonyms:exact_synonym: methionine metabolism
 broad_synonym: methionine and threonine metabolic process;   methionine and threonine metabolism
 xref: UM-BBD_pathwayID:met

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methionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624846:5,203,305...5,208,931
Ensembl chrNW_004624846:5,203,008...5,212,942 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (MGI:5621260|PMID:23190757) BHF-UCL PMID:23190757 MGI:5621260 NCBI chrNW_004624734:36,560,486...36,620,043
Ensembl chrNW_004624734:36,560,486...36,620,026 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004624818:1,184,736...1,202,708
Ensembl chrNW_004624818:1,187,869...1,199,168 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:21121936 RGD:7207080 NCBI chrNW_004624775:13,791,690...13,903,888
Ensembl chrNW_004624775:13,792,043...13,896,559 		JBrowse link
'de novo' L-methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine--homocysteine S-methyltransferase involved_in ISO (PMID:10529246) UniProt PMID:10529246 NCBI chrNW_004624869:3,618,895...3,639,621
Ensembl chrNW_004624869:3,617,948...3,642,860 		JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine--homocysteine S-methyltransferase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624869:3,618,895...3,639,621
Ensembl chrNW_004624869:3,617,948...3,642,860 		JBrowse link
G Bhmt2 betaine--homocysteine S-methyltransferase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624869:3,571,154...3,596,389
Ensembl chrNW_004624869:3,576,369...3,599,275 		JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000104 NCBI chrNW_004624846:5,203,305...5,208,931
Ensembl chrNW_004624846:5,203,008...5,212,942 		JBrowse link
G Apip APAF1 interacting protein involved_in IEA TreeGrafter
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000118 NCBI chrNW_004624767:12,257,591...12,285,968
Ensembl chrNW_004624767:12,257,597...12,280,154 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA TreeGrafter
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000118 NCBI chrNW_004624757:8,456,021...8,488,262
Ensembl chrNW_004624757:8,456,966...8,488,229 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624901:1,105,763...1,110,281
Ensembl chrNW_004624901:1,106,059...1,109,931 		JBrowse link
G Mtap methylthioadenosine phosphorylase involved_in IEA TreeGrafter
UniProt		 GO_REF:0000041 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004624736:25,778,191...25,826,945
Ensembl chrNW_004624736:25,778,240...25,826,530 		JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein involved_in IEA UniProt GO_REF:0000104 NCBI chrNW_004624767:12,257,591...12,285,968
Ensembl chrNW_004624767:12,257,597...12,280,154 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chrNW_004624757:8,456,021...8,488,262
Ensembl chrNW_004624757:8,456,966...8,488,229 		JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624846:5,203,305...5,208,931
Ensembl chrNW_004624846:5,203,008...5,212,942 		JBrowse link
G Apip APAF1 interacting protein involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624767:12,257,591...12,285,968
Ensembl chrNW_004624767:12,257,597...12,280,154 		JBrowse link
G Bhmt betaine--homocysteine S-methyltransferase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15217352) RGD
MGI
UniProt
InterPro		 PMID:15217352 PMID:15845641 GO_REF:0000002 GO_REF:0000117 RGD:1359026 NCBI chrNW_004624869:3,618,895...3,639,621
Ensembl chrNW_004624869:3,617,948...3,642,860 		JBrowse link
G Bhmt2 betaine--homocysteine S-methyltransferase 2 involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000117 NCBI chrNW_004624869:3,571,154...3,596,389
Ensembl chrNW_004624869:3,576,369...3,599,275 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624757:8,456,021...8,488,262
Ensembl chrNW_004624757:8,456,966...8,488,229 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624901:1,105,763...1,110,281
Ensembl chrNW_004624901:1,106,059...1,109,931 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) BHF-UCL PMID:25633902 NCBI chrNW_004624734:36,560,486...36,620,043
Ensembl chrNW_004624734:36,560,486...36,620,026 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15217352) TreeGrafter
MGI		 PMID:15217352 GO_REF:0000118 NCBI chrNW_004624818:1,184,736...1,202,708
Ensembl chrNW_004624818:1,187,869...1,199,168 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11158293) RGD
MGI
UniProt
InterPro
Ensembl
TreeGrafter		 PMID:11158293 PMID:11730351 PMID:15845641 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 RGD:1359026 RGD:1601423 NCBI chrNW_004624775:13,791,690...13,903,888
Ensembl chrNW_004624775:13,792,043...13,896,559 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in IEA TreeGrafter
Ensembl
UniProt		 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624751:5,445,274...5,469,386
Ensembl chrNW_004624751:5,445,241...5,469,657 		JBrowse link
methionine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mat1a methionine adenosyltransferase 1A involved_in ISO (PMID:10677294) UniProt PMID:10677294 NCBI chrNW_004624841:6,843,725...6,864,700
Ensembl chrNW_004624841:6,843,741...6,862,683 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15248
    cellular process 14879
      metabolic process 9692
        sulfur compound metabolic process 293
          sulfur amino acid metabolic process 29
            methionine metabolic process 12
              methionine biosynthetic process + 11
              methionine catabolic process + 1
Path 2
Term Annotations click to browse term
  biological_process 15248
    cellular process 14879
      metabolic process 9692
        small molecule metabolic process 1537
          organic acid metabolic process 812
            oxoacid metabolic process 804
              carboxylic acid metabolic process 792
                alpha-amino acid metabolic process 201
                  L-amino acid metabolic process 172
                    aspartate family amino acid metabolic process 39
                      methionine metabolic process 12
                        methionine biosynthetic process + 11
                        methionine catabolic process + 1
paths to the root