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ONTOLOGY REPORT - ANNOTATIONS


Term:methionine metabolic process
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Accession:GO:0006555 term browser browse the term
Definition:The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
Synonyms:exact_synonym: methionine metabolism
 broad_synonym: methionine and threonine metabolic process;   methionine and threonine metabolism
 xref: UM-BBD_pathwayID:met


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methionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:104,140,027...104,172,782
Ensembl chr14:104,139,952...104,172,271
JBrowse link
G GNMT glycine N-methyltransferase acts_upstream_of_or_within ISO (PMID:17937387) MGI PMID:17937387 NCBI chr17:29,196,142...29,199,728
Ensembl chr17:29,196,321...29,198,947
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:41,590,655...41,663,551
Ensembl chr24:41,590,590...41,666,952
JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:21121936 RGD:7207080 NCBI chr25:73,935,666...74,039,872
Ensembl chr25:73,935,225...74,038,741
JBrowse link
'de novo' L-methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHMT betaine--homocysteine S-methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:73,331,551...73,352,259
Ensembl chr 4:73,332,259...73,352,434
JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHMT betaine--homocysteine S-methyltransferase involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 4:73,331,551...73,352,259
Ensembl chr 4:73,332,259...73,352,434
JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 4:73,289,836...73,310,312
Ensembl chr 4:73,289,652...73,312,358
JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IEA UniProt
InterPro
GO_REF:0000002 GO_REF:0000041 GO_REF:0000104 NCBI chr14:104,140,027...104,172,782
Ensembl chr14:104,139,952...104,172,271
JBrowse link
G APIP APAF1 interacting protein involved_in IEA UniProt
TreeGrafter
InterPro
Ensembl
GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:30,344,658...30,374,741
Ensembl chr 1:30,344,690...30,374,737
JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt
TreeGrafter
Ensembl
InterPro
GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:30,810,727...30,843,252
Ensembl chr 7:30,810,816...30,844,852
JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt
TreeGrafter
GO_REF:0000041 GO_REF:0000118 NCBI chr 6:12,424,835...12,431,911
Ensembl chr 6:12,425,052...12,431,844
JBrowse link
G MTAP methylthioadenosine phosphorylase involved_in IEA UniProt
TreeGrafter
GO_REF:0000041 GO_REF:0000104 GO_REF:0000118 NCBI chr15:84,196,548...84,198,357
Ensembl chr12:57,997,427...58,050,241
JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APIP APAF1 interacting protein involved_in IEA UniProt GO_REF:0000104 NCBI chr 1:30,344,658...30,374,741
Ensembl chr 1:30,344,690...30,374,737
JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 7:30,810,727...30,843,252
Ensembl chr 7:30,810,816...30,844,852
JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 6:12,424,835...12,431,911
Ensembl chr 6:12,425,052...12,431,844
JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr14:104,140,027...104,172,782
Ensembl chr14:104,139,952...104,172,271
JBrowse link
G APIP APAF1 interacting protein involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:30,344,658...30,374,741
Ensembl chr 1:30,344,690...30,374,737
JBrowse link
G BHMT betaine--homocysteine S-methyltransferase acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:15217352) RGD
MGI
UniProt
InterPro
PMID:15217352 PMID:15845641 GO_REF:0000002 GO_REF:0000117 RGD:1359026 NCBI chr 4:73,331,551...73,352,259
Ensembl chr 4:73,332,259...73,352,434
JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 involved_in IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000117 NCBI chr 4:73,289,836...73,310,312
Ensembl chr 4:73,289,652...73,312,358
JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 7:30,810,727...30,843,252
Ensembl chr 7:30,810,816...30,844,852
JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:12,424,835...12,431,911
Ensembl chr 6:12,425,052...12,431,844
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:41,590,655...41,663,551
Ensembl chr24:41,590,590...41,666,952
JBrowse link
G MTHFR methylenetetrahydrofolate reductase acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:15217352) MGI
TreeGrafter
PMID:15217352 GO_REF:0000118 NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:11158293) RGD
TreeGrafter
MGI
UniProt
InterPro
PMID:11158293 PMID:11730351 PMID:15845641 GO_REF:0000002 GO_REF:0000043 GO_REF:0000117 GO_REF:0000118 RGD:1359026 RGD:1601423 NCBI chr25:73,935,666...74,039,872
Ensembl chr25:73,935,225...74,038,741
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in IEA Ensembl
TreeGrafter
UniProt
GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:7,461,521...7,493,032
Ensembl chr 4:7,461,526...7,493,840
JBrowse link
methionine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAT1A methionine adenosyltransferase 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:51,540,162...51,558,076
Ensembl chr 9:51,540,162...51,558,576
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17098
    cellular process 16624
      metabolic process 11180
        sulfur compound metabolic process 315
          sulfur amino acid metabolic process 31
            methionine metabolic process 13
              methionine biosynthetic process + 11
              methionine catabolic process + 1
Path 2
Term Annotations click to browse term
  biological_process 17098
    cellular process 16624
      metabolic process 11180
        small molecule metabolic process 1709
          organic acid metabolic process 913
            oxoacid metabolic process 906
              carboxylic acid metabolic process 890
                alpha-amino acid metabolic process 221
                  L-amino acid metabolic process 187
                    aspartate family amino acid metabolic process 40
                      methionine metabolic process 13
                        methionine biosynthetic process + 11
                        methionine catabolic process + 1
paths to the root