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ONTOLOGY REPORT - ANNOTATIONS

Term:methionine metabolic process
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Accession:GO:0006555 term browser browse the term
Definition:The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
Synonyms:exact_synonym: methionine metabolism
 broad_synonym: methionine and threonine metabolic process;   methionine and threonine metabolism
 xref: UM-BBD_pathwayID:met


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methionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:3,509,162...3,538,064
Ensembl chr2A:3,430,158...3,458,248 		JBrowse link
G GNMT glycine N-methyltransferase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17937387) Ensembl
MGI		 PMID:17937387 GO_REF:0000107 NCBI chr 6:42,550,631...42,554,385
Ensembl chr 6:43,846,560...43,849,679 		JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (MGI:5621260|PMID:23190757)
(PMID:23190757)		 BHF-UCL PMID:23190757 MGI:5621260 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:21121936 RGD:7207080 NCBI chr 1:212,353,195...212,463,304
Ensembl chr 1:217,358,050...217,460,946 		JBrowse link
'de novo' L-methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHMT betaine--homocysteine S-methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:36,181,183...36,201,833
Ensembl chr 5:36,670,854...36,728,993 		JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHMT betaine--homocysteine S-methyltransferase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:36,181,183...36,201,833
Ensembl chr 5:36,670,854...36,728,993 		JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:36,223,429...36,242,187
Ensembl chr 5:36,670,854...36,728,993 		JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IEA Ensembl
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000104 GO_REF:0000107 NCBI chr2A:3,509,162...3,538,064
Ensembl chr2A:3,430,158...3,458,248 		JBrowse link
G APIP APAF1 interacting protein involved_in IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000118 NCBI chr11:34,855,437...34,889,486
Ensembl chr11:34,730,671...34,764,732 		JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt
TreeGrafter
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:41,741,072...41,771,150
Ensembl chr 4:47,591,329...47,621,357 		JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt
TreeGrafter		 GO_REF:0000041 GO_REF:0000118 NCBI chr19:13,327,569...13,336,286
Ensembl chr19:14,060,859...14,067,222 		JBrowse link
G MTAP methylthioadenosine phosphorylase involved_in IEA UniProt
TreeGrafter		 GO_REF:0000041 GO_REF:0000104 GO_REF:0000118 NCBI chr 9:21,637,543...21,769,698
Ensembl chr 9:22,266,376...22,382,218 		JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APIP APAF1 interacting protein involved_in IEA UniProt GO_REF:0000104 NCBI chr11:34,855,437...34,889,486
Ensembl chr11:34,730,671...34,764,732 		JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 4:41,741,072...41,771,150
Ensembl chr 4:47,591,329...47,621,357 		JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr19:13,327,569...13,336,286
Ensembl chr19:14,060,859...14,067,222 		JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADI1 acireductone dioxygenase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr2A:3,509,162...3,538,064
Ensembl chr2A:3,430,158...3,458,248 		JBrowse link
G APIP APAF1 interacting protein involved_in IEA UniProt GO_REF:0000043 NCBI chr11:34,855,437...34,889,486
Ensembl chr11:34,730,671...34,764,732 		JBrowse link
G BHMT betaine--homocysteine S-methyltransferase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15217352) RGD
MGI
UniProt
InterPro		 PMID:15217352 PMID:15845641 GO_REF:0000002 GO_REF:0000117 RGD:1359026 NCBI chr 5:36,181,183...36,201,833
Ensembl chr 5:36,670,854...36,728,993 		JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000117 NCBI chr 5:36,223,429...36,242,187
Ensembl chr 5:36,670,854...36,728,993 		JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:41,741,072...41,771,150
Ensembl chr 4:47,591,329...47,621,357 		JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr19:13,327,569...13,336,286
Ensembl chr19:14,060,859...14,067,222 		JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15217352) MGI
TreeGrafter		 PMID:15217352 GO_REF:0000118 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:11158293) RGD
TreeGrafter
MGI
UniProt
Ensembl
InterPro		 PMID:11158293 PMID:11730351 PMID:15845641 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 RGD:1359026 RGD:1601423 NCBI chr 1:212,353,195...212,463,304
Ensembl chr 1:217,358,050...217,460,946 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:8,195,868...8,228,071
Ensembl chr 5:8,017,403...8,049,322 		JBrowse link
methionine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAT1A methionine adenosyltransferase 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:76,677,815...76,697,512
Ensembl chr10:80,280,063...80,298,291 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16786
    cellular process 16372
      metabolic process 11065
        sulfur compound metabolic process 321
          sulfur amino acid metabolic process 30
            methionine metabolic process 13
              methionine biosynthetic process + 11
              methionine catabolic process + 1
Path 2
Term Annotations click to browse term
  biological_process 16786
    cellular process 16372
      metabolic process 11065
        small molecule metabolic process 1682
          organic acid metabolic process 923
            oxoacid metabolic process 916
              carboxylic acid metabolic process 896
                alpha-amino acid metabolic process 215
                  L-amino acid metabolic process 186
                    aspartate family amino acid metabolic process 41
                      methionine metabolic process 13
                        methionine biosynthetic process + 11
                        methionine catabolic process + 1
paths to the root