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ONTOLOGY REPORT - ANNOTATIONS

Term:leucine catabolic process
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Accession:GO:0006552 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic acid.
Synonyms:exact_synonym: leucine breakdown;   leucine catabolism;   leucine degradation
 xref: MetaCyc:LEU-DEG2-PWY


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leucine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Auh AU RNA binding methylglutaconyl-CoA hydratase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr17:12,329,522...12,424,896
Ensembl chr17:12,329,524...12,424,896 		JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IMP RGD PMID:27472223 RGD:39131293 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633 		JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068 		JBrowse link
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:76,757,301...76,887,300
Ensembl chr 8:76,757,497...76,886,816 		JBrowse link
G Ivd isovaleryl-CoA dehydrogenase involved_in IEA
ISO
IDA
IBA		 GO_REF:0000041
(PMID:7640268)
PMID:6401713
PMID:21873635		 UniProt
RGD		 PMID:7640268 PMID:6401713 PMID:21873635 GO_REF:0000041, RGD:8554099, RGD:13792537 NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575 		JBrowse link
G Mccc1 methylcrotonyl-CoA carboxylase subunit 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:118,799,147...118,851,181
Ensembl chr 2:118,799,150...118,851,222 		JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 involved_in IBA
IEA		 PMID:21873635
GO_REF:0000041		 UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    metabolic process 11591
      catabolic process 2562
        cellular catabolic process 2063
          organic acid catabolic process 245
            alpha-amino acid catabolic process 92
              leucine catabolic process 7
                D-leucine catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 18877
    metabolic process 11591
      cellular metabolic process 9831
        organic acid metabolic process 1001
          oxoacid metabolic process 987
            carboxylic acid metabolic process 972
              cellular amino acid metabolic process 276
                branched-chain amino acid metabolic process 24
                  leucine metabolic process 10
                    leucine catabolic process 7
                      D-leucine catabolic process 0
paths to the root