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ONTOLOGY REPORT - ANNOTATIONS


Term:leucine metabolic process
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Accession:GO:0006551 term browser browse the term
Definition:The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid.
Synonyms:exact_synonym: leucine metabolism



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leucine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat2 branched chain amino acid transaminase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3028726|MGI:3772355 (MGI:3027291|PMID:14755340), (MGI:3770498|PMID:17767905)
Ensembl
RGD
PMID:14755340 PMID:17767905 GO_REF:0000107 MGI:3027291 MGI:3770498 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Dao D-amino-acid oxidase acts_upstream_of_or_within ISO MGI:3528694 (MGI:3525958|PMID:15026304) RGD PMID:15026304 MGI:3525958 NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741
JBrowse link
G Ivd isovaleryl-CoA dehydrogenase TAS RGD PMID:2777793 RGD:631718 NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
JBrowse link
leucine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat1 branched chain amino acid transaminase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:11733007 PMID:21873635 RGD:1582175, RGD:13792537 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
leucine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Auh AU RNA binding methylglutaconyl-CoA hydratase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr17:12,329,522...12,424,896
Ensembl chr17:12,329,524...12,424,896
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IMP RGD PMID:27472223 RGD:39131293 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068
JBrowse link
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:76,757,301...76,887,300
Ensembl chr 8:76,757,497...76,886,816
JBrowse link
G Ivd isovaleryl-CoA dehydrogenase involved_in IEA
IBA
IDA
ISO
GO_REF:0000041
PMID:21873635
PMID:6401713
(PMID:7640268)
UniProt
RGD
PMID:7640268 PMID:21873635 PMID:6401713 GO_REF:0000041, RGD:13792537, RGD:8554099 NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
JBrowse link
G Mccc1 methylcrotonyl-CoA carboxylase subunit 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:118,799,147...118,851,181
Ensembl chr 2:118,799,150...118,851,222
JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    metabolic process 12042
      primary metabolic process 10740
        cellular amino acid metabolic process 277
          alpha-amino acid metabolic process 199
            leucine metabolic process 10
              D-leucine metabolic process + 0
              leucine biosynthetic process + 2
              leucine catabolic process + 7
Path 2
Term Annotations click to browse term
  biological_process 19834
    metabolic process 12042
      small molecule metabolic process 1829
        organic acid metabolic process 1026
          oxoacid metabolic process 993
            carboxylic acid metabolic process 972
              cellular amino acid metabolic process 277
                alpha-amino acid metabolic process 199
                  leucine metabolic process 10
                    D-leucine metabolic process + 0
                    leucine biosynthetic process + 2
                    leucine catabolic process + 7
paths to the root