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ONTOLOGY REPORT - ANNOTATIONS


Term:isoleucine catabolic process
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Accession:GO:0006550 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
Synonyms:exact_synonym: isoleucine breakdown;   isoleucine catabolism;   isoleucine degradation
 xref: MetaCyc:ILEUDEG-PWY


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isoleucine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadsb acyl-CoA dehydrogenase, short/branched chain involved_in ISO
IEA
ISS
(PMID:11013134)
GO_REF:0000041
GO_REF:0000024
RGD
UniProt
PMID:11013134 GO_REF:0000024 GO_REF:0000041 NCBI chr 1:201,981,362...202,022,771
Ensembl chr 1:201,981,357...202,021,008
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:1979337), (PMID:8103405) RGD PMID:1979337 PMID:8103405 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 acts_upstream_of_or_within
involved_in
IDA
ISO
IEA
MGI:3772355 (MGI:3770498|PMID:17767905)
GO_REF:0000107
RGD
Ensembl
PMID:17767905, PMID:11733007 GO_REF:0000107 MGI:3770498, RGD:1582175 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IMP RGD PMID:27472223 RGD:39131293 NCBI chr 1:199,351,628...199,356,299
Ensembl chr 1:199,351,628...199,356,881
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 involved_in ISO
ISS
IEA
(PMID:18996107), (PMID:19706438)
GO_REF:0000024
GO_REF:0000041
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:18996107 PMID:19706438 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr  X:21,696,796...21,699,241
Ensembl chr  X:21,696,772...21,699,241
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19638
    metabolic process 11894
      cellular metabolic process 10847
        organic acid metabolic process 1006
          branched-chain amino acid metabolic process 16
            isoleucine metabolic process 8
              isoleucine catabolic process 5
Path 2
Term Annotations click to browse term
  biological_process 19638
    metabolic process 11894
      cellular metabolic process 10847
        organic acid metabolic process 1006
          oxoacid metabolic process 969
            carboxylic acid metabolic process 951
              cellular amino acid metabolic process 265
                alpha-amino acid metabolic process 190
                  alpha-amino acid catabolic process 81
                    isoleucine catabolic process 5
paths to the root