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ONTOLOGY REPORT - ANNOTATIONS


Term:isoleucine catabolic process
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Accession:GO:0006550 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
Synonyms:exact_synonym: isoleucine breakdown;   isoleucine catabolism;   isoleucine degradation
 xref: MetaCyc:ILEUDEG-PWY



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isoleucine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadsb acyl-CoA dehydrogenase, short/branched chain involved_in ISO
IEA
ISS
(PMID:11013134)
GO_REF:0000107
GO_REF:0000041
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:11013134 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:1979337), (PMID:8103405) RGD PMID:1979337 PMID:8103405 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 acts_upstream_of_or_within IDA
ISO
MGI:3772355 (MGI:3770498|PMID:17767905) RGD PMID:17767905 PMID:11733007 MGI:3770498, RGD:1582175 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IMP RGD PMID:27472223 RGD:39131293 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 involved_in ISO
ISS
IEA
(PMID:18996107), (PMID:19706438)
GO_REF:0000024
GO_REF:0000041
RGD
UniProt
PMID:18996107 PMID:19706438 GO_REF:0000024 GO_REF:0000041 NCBI chr  X:21,089,152...21,091,597
Ensembl chr  X:21,089,122...21,109,488
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    metabolic process 11791
      catabolic process 2552
        cellular catabolic process 2174
          organic acid catabolic process 235
            alpha-amino acid catabolic process 89
              isoleucine catabolic process 5
Path 2
Term Annotations click to browse term
  biological_process 19512
    metabolic process 11791
      cellular metabolic process 10675
        organic acid metabolic process 1009
          oxoacid metabolic process 978
            carboxylic acid metabolic process 962
              cellular amino acid metabolic process 276
                branched-chain amino acid metabolic process 24
                  isoleucine metabolic process 8
                    isoleucine catabolic process 5
paths to the root