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ONTOLOGY REPORT - ANNOTATIONS


Term:isoleucine metabolic process
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Accession:GO:0006549 term browser browse the term
Definition:The chemical reactions and pathways involving isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
Synonyms:exact_synonym: isoleucine metabolism


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isoleucine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat2 branched chain amino acid transaminase 2 ISO MGI:MGI:3028726 (MGI:MGI:3027291|PMID:14755340) RGD PMID:14755340 MGI:MGI:3027291 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080
JBrowse link
isoleucine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ilvbl ilvB acetolactate synthase like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:14,044,586...14,054,639
Ensembl chr 7:14,044,586...14,054,639
JBrowse link
G Sds serine dehydratase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,620,429...41,627,741
Ensembl chr12:41,620,393...41,627,741
JBrowse link
G Sdsl serine dehydratase-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,636,994...41,647,205
Ensembl chr12:41,636,994...41,647,205
JBrowse link
isoleucine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadsb acyl-CoA dehydrogenase, short/branched chain ISO
ISS
(PMID:11013134)
GO_REF:0000024
RGD
UniProt
PMID:11013134 GO_REF:0000024 NCBI chr 1:201,981,362...202,022,771
Ensembl chr 1:201,981,357...202,021,008
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 ISO (PMID:1979337), (PMID:8103405) RGD PMID:1979337, PMID:8103405 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 IDA
ISO
IEA
MGI:MGI:3772355 (MGI:MGI:3770498|PMID:17767905)
GO_REF:0000107
RGD
Ensembl
PMID:17767905, PMID:11733007 GO_REF:0000107, MGI:MGI:3770498, RGD:1582175 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IMP RGD PMID:27472223 RGD:39131293 NCBI chr 1:199,351,628...199,356,299
Ensembl chr 1:199,351,628...199,356,881
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 ISO
ISS
(PMID:18996107), (PMID:19706438)
GO_REF:0000024
RGD
UniProt
PMID:18996107, PMID:19706438 GO_REF:0000024 NCBI chr  X:21,696,796...21,699,241
Ensembl chr  X:21,696,772...21,699,241
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      primary metabolic process 10920
        cellular amino acid metabolic process 276
          alpha-amino acid metabolic process 201
            isoleucine metabolic process 8
              isoleucine biosynthetic process + 3
              isoleucine catabolic process 5
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      small molecule metabolic process 1874
        organic acid metabolic process 1095
          oxoacid metabolic process 1066
            carboxylic acid metabolic process 1009
              cellular amino acid metabolic process 276
                alpha-amino acid metabolic process 201
                  isoleucine metabolic process 8
                    isoleucine biosynthetic process + 3
                    isoleucine catabolic process 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.