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ONTOLOGY REPORT - ANNOTATIONS


Term:isoleucine metabolic process
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Accession:GO:0006549 term browser browse the term
Definition:The chemical reactions and pathways involving isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
Synonyms:exact_synonym: isoleucine metabolism



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isoleucine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat2 branched chain amino acid transaminase 2 acts_upstream_of_or_within ISO MGI:3028726 (MGI:3027291|PMID:14755340) RGD PMID:14755340 MGI:3027291 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
isoleucine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ilvbl ilvB acetolactate synthase like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:11,039,870...11,049,924
Ensembl chr 7:11,039,871...11,049,924
JBrowse link
G Sds serine dehydratase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Sdsl serine dehydratase-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:36,099,693...36,109,914
Ensembl chr12:36,099,693...36,109,906
JBrowse link
isoleucine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadsb acyl-CoA dehydrogenase, short/branched chain involved_in ISO
IEA
ISS
(PMID:11013134)
GO_REF:0000107
GO_REF:0000041
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:11013134 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:1979337), (PMID:8103405) RGD PMID:1979337 PMID:8103405 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 acts_upstream_of_or_within
involved_in
IDA
ISO
IEA
MGI:3772355 (MGI:3770498|PMID:17767905)
GO_REF:0000107
RGD
Ensembl
PMID:17767905 PMID:11733007 GO_REF:0000107 MGI:3770498, RGD:1582175 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IMP RGD PMID:27472223 RGD:39131293 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 involved_in ISO
IEA
ISS
(PMID:18996107), (PMID:19706438)
GO_REF:0000107
GO_REF:0000041
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:18996107 PMID:19706438 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr  X:21,089,152...21,091,597
Ensembl chr  X:21,089,122...21,109,488
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19541
    metabolic process 11844
      primary metabolic process 10558
        cellular amino acid metabolic process 277
          alpha-amino acid metabolic process 199
            isoleucine metabolic process 8
              isoleucine biosynthetic process + 3
              isoleucine catabolic process 5
Path 2
Term Annotations click to browse term
  biological_process 19541
    metabolic process 11844
      small molecule metabolic process 1806
        organic acid metabolic process 1016
          oxoacid metabolic process 984
            carboxylic acid metabolic process 963
              cellular amino acid metabolic process 277
                alpha-amino acid metabolic process 199
                  isoleucine metabolic process 8
                    isoleucine biosynthetic process + 3
                    isoleucine catabolic process 5
paths to the root