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ONTOLOGY REPORT - ANNOTATIONS


Term:glycine metabolic process
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Accession:GO:0006544 term browser browse the term
Definition:The chemical reactions and pathways involving glycine, aminoethanoic acid.
Synonyms:exact_synonym: glycine metabolism


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glycine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO RGD PMID:4078017 RGD:2301990 NCBI chr13:197,130,898...197,158,797
Ensembl chr13:197,130,904...197,161,891
JBrowse link
G GNMT glycine N-methyltransferase ISO PMID:10756111 RGD
CAFA
PMID:10756111, PMID:18501206 RGD:12793006, RGD:7242952 NCBI chr 7:38,038,359...38,041,218
Ensembl chr 7:38,038,358...38,041,218
JBrowse link
G LOC100517803 glycine N-phenylacetyltransferase IBA (PMID:21873635) GO_Central PMID:21873635
G LOC100518109 glycine N-acyltransferase IEA Ensembl GO_REF:0000107 NCBI chr 2:12,365,082...12,384,741 JBrowse link
G LOC100518644 glycine N-acyltransferase-like IEA Ensembl GO_REF:0000107 NCBI chr 2:12,404,416...12,422,192 JBrowse link
G LOC102158534 bile acid-CoA:amino acid N-acyltransferase-like IEA Ensembl GO_REF:0000107 NCBI chr 1:243,065,668...243,084,816
Ensembl chr 1:243,065,795...243,084,287
JBrowse link
G PHGDH phosphoglycerate dehydrogenase IEA Ensembl GO_REF:0000107 NCBI chr 4:101,445,977...101,478,144
Ensembl chr 4:101,408,308...101,478,144
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:60,414,421...60,435,451
Ensembl chr12:60,414,446...60,435,450
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:22,535,780...22,540,322
Ensembl chr 5:22,532,894...22,540,321
JBrowse link
glycine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC110255953 probable low-specificity L-threonine aldolase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:3,728,742...3,734,209 JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 ISO from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr12:60,414,421...60,435,451
Ensembl chr12:60,414,446...60,435,450
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 ISO from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr 5:22,535,780...22,540,322
Ensembl chr 5:22,532,894...22,540,321
JBrowse link
glycine biosynthetic process from serine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SHMT1 serine hydroxymethyltransferase 1 IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr12:60,414,421...60,435,451
Ensembl chr12:60,414,446...60,435,450
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr 5:22,535,780...22,540,322
Ensembl chr 5:22,532,894...22,540,321
JBrowse link
glycine biosynthetic process, by transamination of glyoxylate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGXT alanine--glyoxylate and serine--pyruvate aminotransferase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:139,720,648...139,730,737
Ensembl chr15:139,720,612...139,730,736
JBrowse link
G AGXT2 alanine--glyoxylate aminotransferase 2 IEA Ensembl GO_REF:0000107 NCBI chr16:20,576,661...20,617,008
Ensembl chr16:20,576,660...20,617,017
JBrowse link
glycine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMT aminomethyltransferase IEA InterPro GO_REF:0000002 NCBI chr13:31,995,600...32,002,514
Ensembl chr13:31,995,595...32,002,470
JBrowse link
G GLDC glycine decarboxylase IEA InterPro GO_REF:0000002 NCBI chr 1:215,608,854...215,715,062
Ensembl chr 1:215,608,849...215,715,061
JBrowse link
glycine decarboxylation via glycine cleavage system term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMT aminomethyltransferase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:31,995,600...32,002,514
Ensembl chr13:31,995,595...32,002,470
JBrowse link
G GCSH glycine cleavage system protein H IEA UniProt GO_REF:0000104 NCBI chr 6:7,171,186...7,184,732 JBrowse link
G GLDC glycine decarboxylase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:215,608,854...215,715,062
Ensembl chr 1:215,608,849...215,715,061
JBrowse link
L-threonine catabolic process to glycine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TDH L-threonine 3-dehydrogenase IEA UniProt GO_REF:0000041 NCBI chr14:14,577,009...14,597,695 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16548
    metabolic process 10584
      primary metabolic process 9383
        cellular amino acid metabolic process 257
          alpha-amino acid metabolic process 182
            serine family amino acid metabolic process 38
              glycine metabolic process 16
                L-threonine catabolic process to glycine 1
                glycine betaine biosynthetic process from glycine 0
                glycine biosynthetic process + 5
                glycine catabolic process + 3
                protoporphyrinogen IX biosynthetic process from glycine 0
                tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
Path 2
Term Annotations click to browse term
  biological_process 16548
    metabolic process 10584
      cellular metabolic process 9574
        organic acid metabolic process 868
          oxoacid metabolic process 834
            carboxylic acid metabolic process 817
              cellular amino acid metabolic process 257
                alpha-amino acid metabolic process 182
                  serine family amino acid metabolic process 38
                    glycine metabolic process 16
                      L-threonine catabolic process to glycine 1
                      glycine betaine biosynthetic process from glycine 0
                      glycine biosynthetic process + 5
                      glycine catabolic process + 3
                      protoporphyrinogen IX biosynthetic process from glycine 0
                      tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.