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ONTOLOGY REPORT - ANNOTATIONS


Term:glycine metabolic process
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Accession:GO:0006544 term browser browse the term
Definition:The chemical reactions and pathways involving glycine, aminoethanoic acid.
Synonyms:exact_synonym: glycine metabolism


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glycine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baat bile acid-CoA:amino acid N-acyltransferase ISO (PMID:8034703) UniProtKB PMID:8034703 NCBI chrNW_004955419:24,469,213...24,521,728
Ensembl chrNW_004955419:24,443,172...24,520,467
JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO RGD PMID:4078017 RGD:2301990 NCBI chrNW_004955407:32,944,638...32,975,142
Ensembl chrNW_004955407:32,944,164...32,973,863
JBrowse link
G Glyat glycine-N-acyltransferase ISO (PMID:22475485) UniProtKB PMID:22475485 NCBI chrNW_004955511:3,670,736...3,683,751
Ensembl chrNW_004955511:3,667,607...3,683,886
JBrowse link
G Gnmt glycine N-methyltransferase ISO PMID:10756111 CAFA
RGD
PMID:10756111, PMID:18501206 RGD:12793006, RGD:7242952 NCBI chrNW_004955437:8,944,288...8,946,642
Ensembl chrNW_004955437:8,944,047...8,946,642
JBrowse link
G Phgdh phosphoglycerate dehydrogenase ISO (MGI:3835979|PMID:19114063) MGI PMID:19114063 MGI:3835979 NCBI chrNW_004955435:22,757,473...22,803,123
Ensembl chrNW_004955435:22,757,454...22,803,123
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 ISO (PMID:24698160) UniProtKB
RGD
PMID:15671219, PMID:24698160 RGD:1359815 NCBI chrNW_004955478:10,972,791...11,001,535
Ensembl chrNW_004955478:10,978,139...11,001,202
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 ISO (PMID:19513116)
(PMID:25619277), (PMID:29180469)
RGD
BHF-UCL
UniProtKB
PMID:10457370, PMID:15671219, PMID:19513116, PMID:25619277, PMID:29180469 RGD:1359815, RGD:2300380 NCBI chrNW_004955458:4,957,614...4,962,691
Ensembl chrNW_004955458:4,957,602...4,962,691
JBrowse link
glycine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shmt1 serine hydroxymethyltransferase 1 ISO from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chrNW_004955478:10,972,791...11,001,535
Ensembl chrNW_004955478:10,978,139...11,001,202
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 ISO from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chrNW_004955458:4,957,614...4,962,691
Ensembl chrNW_004955458:4,957,602...4,962,691
JBrowse link
glycine biosynthetic process from serine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shmt1 serine hydroxymethyltransferase 1 ISO in the presence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chrNW_004955478:10,972,791...11,001,535
Ensembl chrNW_004955478:10,978,139...11,001,202
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 ISO in the presence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chrNW_004955458:4,957,614...4,962,691
Ensembl chrNW_004955458:4,957,602...4,962,691
JBrowse link
glycine biosynthetic process, by transamination of glyoxylate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase ISO (PMID:22198249) UniProtKB
RGD
PMID:12383475, PMID:22198249 RGD:1599457 NCBI chrNW_004955542:710,506...720,564
Ensembl chrNW_004955542:710,005...717,741
JBrowse link
G Agxt2 alanine--glyoxylate aminotransferase 2 ISO (PMID:20018850) BHF-UCL PMID:20018850 NCBI chrNW_004955426:20,102,368...20,142,596
Ensembl chrNW_004955426:20,101,620...20,142,620
JBrowse link
glycine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gldc glycine decarboxylase ISO (PMID:28244183) UniProtKB PMID:28244183 NCBI chrNW_004955434:10,431,434...10,533,118
Ensembl chrNW_004955434:10,431,983...10,533,002
JBrowse link
glycine decarboxylation via glycine cleavage system term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amt aminomethyltransferase ISO (PMID:16051266) UniProtKB PMID:16051266 NCBI chrNW_004955532:1,351,743...1,358,220
Ensembl chrNW_004955532:1,351,743...1,358,220
JBrowse link
G Gcsh glycine cleavage system protein H ISO RGD PMID:6402507 RGD:1598699 NCBI chrNW_004955522:3,858,156...3,869,730 JBrowse link
G Gldc glycine decarboxylase ISO RGD PMID:6778858 RGD:1642728 NCBI chrNW_004955434:10,431,434...10,533,118
Ensembl chrNW_004955434:10,431,983...10,533,002
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11892
    metabolic process 7608
      primary metabolic process 6749
        cellular amino acid metabolic process 179
          alpha-amino acid metabolic process 132
            serine family amino acid metabolic process 30
              glycine metabolic process 12
                L-threonine catabolic process to glycine 0
                glycine betaine biosynthetic process from glycine 0
                glycine biosynthetic process + 4
                glycine catabolic process + 3
                protoporphyrinogen IX biosynthetic process from glycine 0
                tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
Path 2
Term Annotations click to browse term
  biological_process 11892
    metabolic process 7608
      cellular metabolic process 7024
        organic acid metabolic process 628
          oxoacid metabolic process 601
            carboxylic acid metabolic process 597
              cellular amino acid metabolic process 179
                alpha-amino acid metabolic process 132
                  serine family amino acid metabolic process 30
                    glycine metabolic process 12
                      L-threonine catabolic process to glycine 0
                      glycine betaine biosynthetic process from glycine 0
                      glycine biosynthetic process + 4
                      glycine catabolic process + 3
                      protoporphyrinogen IX biosynthetic process from glycine 0
                      tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.