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ONTOLOGY REPORT - ANNOTATIONS


Term:glycine metabolic process
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Accession:GO:0006544 term browser browse the term
Definition:The chemical reactions and pathways involving glycine, aminoethanoic acid.
Synonyms:exact_synonym: glycine metabolism


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glycine metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baat bile acid CoA:amino acid N-acyltransferase ISO (PMID:8034703) RGD PMID:8034703 NCBI chr 5:64,768,397...64,777,368
Ensembl chr 5:64,768,401...64,777,368
JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase IDA RGD PMID:4078017 RGD:2301990 NCBI chr11:31,780,477...31,805,728
Ensembl chr11:31,780,487...31,805,728
JBrowse link
G Glyat glycine-N-acyltransferase ISO
IBA
IEA
ISS
(PMID:22475485)
PMID:21873635
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:22475485, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr 1:229,060,125...229,081,113
Ensembl chr 1:229,063,714...229,080,410
JBrowse link
G Glyatl1 glycine-N-acyltransferase-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:229,039,889...229,055,127
Ensembl chr 1:229,030,233...229,055,127
JBrowse link
G Gnmt glycine N-methyltransferase IMP PMID:10756111 RGD
CAFA
PMID:18501206, PMID:10756111 RGD:7242952, RGD:12793006 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Phgdh phosphoglycerate dehydrogenase ISO MGI:MGI:3769591 (MGI:MGI:3835979|PMID:19114063) RGD PMID:19114063 MGI:MGI:3835979 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 TAS
IBA
ISO
IDA
PMID:21873635
(PMID:24698160)
RGD PMID:24698160, PMID:15671219, PMID:21873635, PMID:15671219 RGD:1359815, RGD:13792537, RGD:1359815 NCBI chr10:47,030,813...47,059,216
Ensembl chr10:47,031,050...47,059,216
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 TAS
IBA
ISO
IDA
PMID:21873635
UniProtKB:G3HW36 (PMID:19513116), (PMID:25619277), (PMID:29180469)
RGD PMID:19513116, PMID:25619277, PMID:29180469, PMID:15671219, PMID:21873635, PMID:10457370, PMID:15671219 RGD:1359815, RGD:13792537, RGD:2300380, RGD:1359815 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
glycine biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC688286 similar to threonine aldolase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:106,877,585...106,883,706
Ensembl chr10:106,878,085...106,883,423
JBrowse link
G Sardh sarcosine dehydrogenase TAS RGD PMID:9839943 RGD:634034 NCBI chr 3:5,737,203...5,802,153
Ensembl chr 3:5,737,200...5,802,129
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 IDA from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr10:47,030,813...47,059,216
Ensembl chr10:47,031,050...47,059,216
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 IDA from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
glycine biosynthetic process from serine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shmt1 serine hydroxymethyltransferase 1 IDA
IBA
in the presence of tetrahydrofolate
PMID:21873635
RGD
GO_Central
PMID:3110140, PMID:21873635 RGD:2300383, RGD:13792537 NCBI chr10:47,030,813...47,059,216
Ensembl chr10:47,031,050...47,059,216
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 IDA
IBA
in the presence of tetrahydrofolate
PMID:21873635
RGD
GO_Central
PMID:3110140, PMID:21873635 RGD:2300383, RGD:13792537 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
glycine biosynthetic process, by transamination of glyoxylate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase IDA
IBA
ISO
PMID:21873635
(PMID:22198249)
RGD PMID:22198249, PMID:12383475, PMID:21873635 RGD:1599457, RGD:13792537 NCBI chr 9:100,281,339...100,291,292
Ensembl chr 9:100,281,339...100,291,291
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 ISO (PMID:20018850) RGD PMID:20018850 NCBI chr 2:60,337,667...60,379,144
Ensembl chr 2:60,337,667...60,379,420
JBrowse link
glycine catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gldc glycine decarboxylase ISO (PMID:28244183) RGD PMID:28244183 NCBI chr 1:248,295,140...248,377,122
Ensembl chr 1:248,297,331...248,377,093
JBrowse link
glycine decarboxylation via glycine cleavage system term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07007134.1 IEA GO_REF:0000104 UniProt GO_REF:0000104 Ensembl chr 1:282,557,426...282,557,923 JBrowse link
G AABR07067762.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 9:61,738,471...61,739,134 JBrowse link
G Amt aminomethyltransferase ISO
IBA
(PMID:16051266)
PMID:21873635
RGD PMID:16051266, PMID:21873635 RGD:13792537 NCBI chr 8:117,068,388...117,078,633
Ensembl chr 8:117,068,582...117,077,913
JBrowse link
G Gcsh glycine cleavage system protein H IMP RGD PMID:6402507 RGD:1598699 NCBI chr19:49,522,054...49,532,811
Ensembl chr19:49,522,054...49,532,811
JBrowse link
G Gldc glycine decarboxylase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:6778858, PMID:21873635 RGD:1642728, RGD:13792537 NCBI chr 1:248,295,140...248,377,122
Ensembl chr 1:248,297,331...248,377,093
JBrowse link
G RGD1563099 similar to Gcsh protein IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:282,557,429...282,557,979 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      primary metabolic process 10901
        cellular amino acid metabolic process 274
          alpha-amino acid metabolic process 198
            serine family amino acid metabolic process 40
              glycine metabolic process 18
                L-threonine catabolic process to glycine 0
                glycine betaine biosynthetic process from glycine 0
                glycine biosynthetic process + 6
                glycine catabolic process + 6
                protoporphyrinogen IX biosynthetic process from glycine 0
                tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
Path 2
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      cellular metabolic process 11064
        organic acid metabolic process 1089
          oxoacid metabolic process 1060
            carboxylic acid metabolic process 1004
              cellular amino acid metabolic process 274
                alpha-amino acid metabolic process 198
                  serine family amino acid metabolic process 40
                    glycine metabolic process 18
                      L-threonine catabolic process to glycine 0
                      glycine betaine biosynthetic process from glycine 0
                      glycine biosynthetic process + 6
                      glycine catabolic process + 6
                      protoporphyrinogen IX biosynthetic process from glycine 0
                      tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.