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ONTOLOGY REPORT - ANNOTATIONS


Term:glutamine metabolic process
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Accession:GO:0006541 term browser browse the term
Definition:The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.
Synonyms:exact_synonym: glutamine metabolism


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glutamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adssl1 adenylosuccinate synthase like 1 IEP RGD PMID:12522136 RGD:5135508 NCBI chr 6:137,184,818...137,206,694
Ensembl chr 6:137,184,820...137,206,693
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEP
IBA
IDA
PMID:21873635 RGD
GO_Central
PMID:2474281, PMID:21873635, PMID:2803258 RGD:5132588, RGD:13792537, RGD:10755425 NCBI chr 6:26,657,507...26,680,459
Ensembl chr 6:26,657,780...26,680,284
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Ctps1 CTP synthase 1 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 5:139,475,934...139,505,065
Ensembl chr 5:139,475,934...139,505,065
JBrowse link
G Ctps2 CTP synthase 2 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:33,383,087...33,522,852
Ensembl chr  X:33,383,087...33,522,836
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:118,852,046...118,901,583
Ensembl chr 4:118,852,062...118,901,591
JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:35,279,237...35,325,506
Ensembl chr10:35,279,236...35,325,508
JBrowse link
G Gls glutaminase IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gls2 glutaminase 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:2,605,679...2,621,853
Ensembl chr 7:2,605,719...2,621,852
JBrowse link
G Glud1 glutamate dehydrogenase 1 ISO
ISS
(MGI:MGI:5499916|PMID:23663782)
GO_REF:0000024
RGD
UniProt
PMID:23663782 GO_REF:0000024, MGI:MGI:5499916 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Gmps guanine monophosphate synthase IEA GO_REF:0000104
GO_REF:0000043
UniProt GO_REF:0000043, GO_REF:0000104 NCBI chr 2:154,555,967...154,590,662
Ensembl chr 2:154,555,871...154,590,662
JBrowse link
G Mecp2 methyl CpG binding protein 2 ISO MGI:MGI:2137311 (MGI:MGI:3769075|PMID:17237885) RGD PMID:17237885 MGI:MGI:3769075 NCBI chr  X:156,650,389...156,713,813
Ensembl chr  X:156,655,960...156,705,233
JBrowse link
G Nit2 nitrilase family, member 2 ISO
IBA
(PMID:22674578)
PMID:21873635
RGD PMID:22674578, PMID:21873635 RGD:13792537 NCBI chr11:45,462,345...45,473,107
Ensembl chr11:45,462,345...45,473,104
JBrowse link
G Pfas phosphoribosylformylglycinamidine synthase IDA RGD PMID:3436958 RGD:1599004 NCBI chr10:55,571,881...55,593,384
Ensembl chr10:55,571,118...55,589,978
JBrowse link
G Phgdh phosphoglycerate dehydrogenase ISO MGI:MGI:3769591 (MGI:MGI:3835979|PMID:19114063) RGD PMID:19114063 MGI:MGI:3835979 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Sirt4 sirtuin 4 ISO (MGI:MGI:5490691|PMID:23562301), (MGI:MGI:5499916|PMID:23663782) RGD PMID:23562301, PMID:23663782 MGI:MGI:5490691, MGI:MGI:5499916 NCBI chr12:46,862,358...46,876,593
Ensembl chr12:46,868,416...46,876,592
JBrowse link
ammonia assimilation cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase ISO
IEA
MGI:MGI:3604881 (MGI:MGI:3604426|PMID:12559843)
GO_REF:0000107
RGD
Ensembl
PMID:12559843 GO_REF:0000107, MGI:MGI:3604426 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Glul glutamate-ammonia ligase TAS
IDA
RGD PMID:1674354, PMID:28323 RGD:632694, RGD:2301547 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
glutamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glul glutamate-ammonia ligase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:4403443, PMID:21873635, PMID:28323 RGD:2301548, RGD:13792537, RGD:2301547 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Lgsn lengsin, lens protein with glutamine synthetase domain NOT IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:37,458,603...37,490,117
Ensembl chr 9:37,462,693...37,490,108
JBrowse link
glutamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gls glutaminase TAS
IBA
ISO
ISS
IEA
PMID:21873635
MGI:MGI:3514104 (MGI:MGI:3623875|PMID:16641247), (MGI:MGI:5320252|PMID:22228304)
GO_REF:0000024
(PMID:22049910)
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:16641247, PMID:22049910, PMID:22228304, PMID:1918000, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3623875, MGI:MGI:5320252, RGD:728510, RGD:13792537 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gls2 glutaminase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:2,605,679...2,621,853
Ensembl chr 7:2,605,719...2,621,852
JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase IDA RGD PMID:8463258 RGD:633710 NCBI chr14:33,580,541...33,614,919
Ensembl chr14:33,580,541...33,614,919
JBrowse link
positive regulation of ammonia assimilation cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 ISO
IEA
(MGI:MGI:5306122|PMID:21757002)
GO_REF:0000107
RGD
Ensembl
PMID:21757002 GO_REF:0000107, MGI:MGI:5306122 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      primary metabolic process 10920
        cellular amino acid metabolic process 276
          alpha-amino acid metabolic process 201
            glutamine family amino acid metabolic process 75
              glutamine metabolic process 22
                D-glutamine metabolic process 0
                ammonia assimilation cycle + 3
                cyclization of glutamine involved in intein-mediated protein splicing 0
                glutamine biosynthetic process + 2
                glutamine catabolic process + 3
                peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamine 0
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      cellular metabolic process 11085
        organic acid metabolic process 1095
          oxoacid metabolic process 1066
            carboxylic acid metabolic process 1009
              cellular amino acid metabolic process 276
                alpha-amino acid metabolic process 201
                  glutamine family amino acid metabolic process 75
                    glutamine metabolic process 22
                      D-glutamine metabolic process 0
                      ammonia assimilation cycle + 3
                      cyclization of glutamine involved in intein-mediated protein splicing 0
                      glutamine biosynthetic process + 2
                      glutamine catabolic process + 3
                      peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamine 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.