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ONTOLOGY REPORT - ANNOTATIONS

Term:glutamate metabolic process
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Accession:GO:0006536 term browser browse the term
Definition:The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
Synonyms:exact_synonym: glutamate metabolism;   glutamic acid metabolic process;   glutamic acid metabolism
 xref: Wikipedia:Glutamic_acid


show annotations for term's descendants           Sort by:
glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase involved_in ISO
IEA
ISS		 (PMID:18620547)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18620547 GO_REF:0000024 GO_REF:0000107 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in ISO (PMID:11092761) RGD PMID:11092761 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180159 (PMID:17854388)		 Ensembl
RGD		 PMID:17854388 GO_REF:0000107 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 acts_upstream_of_or_within ISO MGI:1856982 (PMID:28701731) RGD PMID:28701731 NCBI chr 3:109,816,397...109,826,528
Ensembl chr 3:109,816,366...109,828,308 		JBrowse link
G Dglucy D-glutamate cyclase involved_in ISO
IBA		 (MGI:5901965|PMID:28266638)
GO_REF:0000033		 RGD
GO_Central		 PMID:28266638 GO_REF:0000033 MGI:5901965 NCBI chr 6:120,055,480...120,130,910
Ensembl chr 6:120,055,460...120,130,910 		JBrowse link
G Fpgs folylpolyglutamate synthase involved_in ISO (PMID:3619447) RGD PMID:3619447 NCBI chr 3:15,972,800...15,993,592
Ensembl chr 3:15,972,800...15,993,563 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit involved_in ISO
ISS		 (PMID:12663448), (PMID:2294991), (PMID:9841880)
GO_REF:0000024		 RGD
UniProt		 PMID:2294991 PMID:9841880 PMID:12663448 GO_REF:0000024 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit involved_in ISO
ISS		 (PMID:9841880), (PMID:9895302)
GO_REF:0000024		 RGD
UniProt		 PMID:9841880 PMID:9895302 GO_REF:0000024 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 involved_in ISO
ISS		 (PMID:21447318), (PMID:24047895)
GO_REF:0000024		 RGD
UniProt		 PMID:21447318 PMID:24047895 GO_REF:0000024 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Glul glutamate-ammonia ligase IDA RGD PMID:4403443 RGD:2301548 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) RGD PMID:12764149 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089 		JBrowse link
G Nags N-acetylglutamate synthase involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:12049647)		 GO_Central
RGD		 PMID:12049647 GO_REF:0000033 NCBI chr10:87,098,330...87,102,465
Ensembl chr10:87,098,330...87,102,465 		JBrowse link
G Tat tyrosine aminotransferase involved_in ISO
ISS		 (PMID:7999802)
(MGI:5430853|PMID:21153519)
GO_REF:0000024		 RGD
UniProt		 PMID:7999802 PMID:21153519 GO_REF:0000024 MGI:5430853 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
ammonia assimilation cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3604881 (PMID:12559843)		 Ensembl
RGD		 PMID:12559843 GO_REF:0000107 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662 		JBrowse link
G Glul glutamate-ammonia ligase IDA RGD PMID:28323 RGD:2301547 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
arginine catabolic process to glutamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oat ornithine aminotransferase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682 		JBrowse link
glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gls glutaminase involved_in IEA
IBA
ISO
ISS		 GO_REF:0000107
GO_REF:0000118
GO_REF:0000033
(MGI:5320252|PMID:22228304)
GO_REF:0000024
(PMID:16899818), (PMID:22049910)		 Ensembl
TreeGrafter
GO_Central
RGD
UniProt		 PMID:16899818 PMID:22049910 PMID:22228304 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:5320252 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900 		JBrowse link
G Gls2 glutaminase 2 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426 		JBrowse link
G Glud1 glutamate dehydrogenase 1 involved_in ISO (PMID:11032875) RGD PMID:11032875 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:56,097,166...56,191,841
Ensembl chr 3:56,097,269...56,192,100 		JBrowse link
glutamate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gad1 glutamate decarboxylase 1 involved_in ISO
IEA		 (PMID:17384644)
GO_REF:0000107		 RGD
Ensembl		 PMID:17384644 GO_REF:0000107 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Glud1 glutamate dehydrogenase 1 involved_in TAS
IEA
IBA
ISO		 GO_REF:0000118
GO_REF:0000033
(PMID:11032875), (PMID:6121377)		 TreeGrafter
GO_Central
RGD		 PMID:6121377 PMID:11032875 PMID:12684230 GO_REF:0000033 GO_REF:0000118, RGD:1601355 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
glutamate catabolic process to 2-oxoglutarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within
involved_in		 IDA
ISO
IEA		 (PMID:4193185)
GO_REF:0000107		 RGD
Ensembl		 PMID:4193185 PMID:16489927 GO_REF:0000107, RGD:13504861 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within IDA
ISO		 (PMID:4193185) RGD PMID:4193185 PMID:16489927 RGD:13504861 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
glutamate catabolic process to aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:4193185)		 Ensembl
RGD		 PMID:4193185 GO_REF:0000107 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (PMID:4193185) RGD PMID:4193185 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
glutamate catabolic process via 2-oxoglutarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adhfe1 alcohol dehydrogenase, iron containing, 1 involved_in ISO
IEA
ISS		 (PMID:16435184)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:16435184 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517 		JBrowse link
glutamate decarboxylation to succinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gad2 glutamate decarboxylase 2 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:8999827 GO_REF:0000033, RGD:1625237 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
histidine catabolic process to glutamate and formamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amdhd1 amidohydrolase domain containing 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156 		JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735 		JBrowse link
G Hal histidine ammonia lyase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701 		JBrowse link
G Uroc1 urocanate hydratase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:122,844,933...122,876,584
Ensembl chr 4:122,844,926...122,876,591 		JBrowse link
histidine catabolic process to glutamate and formate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amdhd1 amidohydrolase domain containing 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156 		JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735 		JBrowse link
G Hal histidine ammonia lyase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701 		JBrowse link
G Uroc1 urocanate hydratase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:122,844,933...122,876,584
Ensembl chr 4:122,844,926...122,876,591 		JBrowse link
negative regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atcay ATCAY kinesin light chain interacting caytaxin involved_in ISO
IEA
ISS		 (PMID:16899818)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:16899818 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:8,487,763...8,511,527
Ensembl chr 7:8,487,763...8,512,663 		JBrowse link
positive regulation of ammonia assimilation cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO
IEA		 (MGI:5306122|PMID:21757002)
GO_REF:0000107		 RGD
Ensembl		 PMID:21757002 GO_REF:0000107 MGI:5306122 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
positive regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO (MGI:5306122|PMID:21757002) RGD PMID:21757002 MGI:5306122 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
proline catabolic process to glutamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345 		JBrowse link
G Iffo2 intermediate filament family orphan 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:151,830,900...151,876,948
Ensembl chr 5:151,830,701...151,925,345 		JBrowse link
G Prodh proline dehydrogenase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305 		JBrowse link
G Prodh2 proline dehydrogenase 2 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:85,753,558...85,767,165
Ensembl chr 1:85,753,644...85,767,162 		JBrowse link
G Tas1r2 taste 1 receptor member 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:151,909,617...151,925,760
Ensembl chr 5:151,830,701...151,925,345 		JBrowse link
regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway IDA RGD PMID:19858196 RGD:6484536 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:3608695 (PMID:21490221), (PMID:24548853), (PMID:25429150) RGD PMID:21490221 PMID:24548853 PMID:25429150 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      primary metabolic process 10352
        amino acid metabolic process 302
          proteinogenic amino acid metabolic process 175
            glutamine family amino acid metabolic process 75
              glutamate metabolic process 37
                D-glutamate metabolic process 0
                ammonia assimilation cycle + 3
                arginine catabolic process to glutamate 1
                glutamate biosynthetic process + 4
                glutamate catabolic process + 6
                histidine catabolic process to glutamate and formamide 4
                histidine catabolic process to glutamate and formate 4
                negative regulation of glutamate metabolic process + 1
                positive regulation of glutamate metabolic process + 1
                proline catabolic process to glutamate + 5
                regulation of glutamate metabolic process + 4
                tetrapyrrole biosynthetic process from glutamate + 0
Path 2
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular metabolic process 9901
        organic acid metabolic process 1077
          oxoacid metabolic process 1059
            carboxylic acid metabolic process 1040
              alpha-amino acid metabolic process 222
                L-amino acid metabolic process 188
                  glutamine family amino acid metabolic process 75
                    glutamate metabolic process 37
                      D-glutamate metabolic process 0
                      ammonia assimilation cycle + 3
                      arginine catabolic process to glutamate 1
                      glutamate biosynthetic process + 4
                      glutamate catabolic process + 6
                      histidine catabolic process to glutamate and formamide 4
                      histidine catabolic process to glutamate and formate 4
                      negative regulation of glutamate metabolic process + 1
                      positive regulation of glutamate metabolic process + 1
                      proline catabolic process to glutamate + 5
                      regulation of glutamate metabolic process + 4
                      tetrapyrrole biosynthetic process from glutamate + 0
paths to the root