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ONTOLOGY REPORT - ANNOTATIONS


Term:glutamate metabolic process
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Accession:GO:0006536 term browser browse the term
Definition:The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
Synonyms:exact_synonym: glutamate metabolism;   glutamic acid metabolic process;   glutamic acid metabolism
 xref: Wikipedia:Glutamic_acid



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glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase involved_in ISO
ISS
(PMID:18620547)
GO_REF:0000024
RGD
UniProt
PMID:18620547 GO_REF:0000024 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in ISO (PMID:11092761) RGD PMID:11092761 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180159 (MGI:3767902|PMID:17854388)
Ensembl
RGD
PMID:17854388 GO_REF:0000107 MGI:3767902 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
JBrowse link
G Dglucy D-glutamate cyclase involved_in IBA
ISO
PMID:21873635
(MGI:5901965|PMID:28266638)
RGD PMID:28266638 PMID:21873635 MGI:5901965, RGD:13792537 NCBI chr 6:120,055,480...120,130,910
Ensembl chr 6:120,055,460...120,130,910
JBrowse link
G Fpgs folylpolyglutamate synthase involved_in ISO (PMID:3619447) RGD PMID:3619447 NCBI chr 3:15,972,800...15,993,592
Ensembl chr 3:15,972,800...15,993,563
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit involved_in ISO
ISS
(PMID:12663448), (PMID:2294991), (PMID:9841880)
GO_REF:0000024
RGD
UniProt
PMID:2294991 PMID:9841880 PMID:12663448 GO_REF:0000024 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit involved_in ISO
ISS
(PMID:9841880), (PMID:9895302)
GO_REF:0000024
RGD
UniProt
PMID:9841880 PMID:9895302 GO_REF:0000024 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 involved_in ISO
ISS
(PMID:21447318), (PMID:24047895)
GO_REF:0000024
RGD
UniProt
PMID:21447318 PMID:24047895 GO_REF:0000024 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Glul glutamate-ammonia ligase IDA RGD PMID:4403443 RGD:2301548 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) RGD PMID:12764149 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089
JBrowse link
G Nags N-acetylglutamate synthase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2388220|PMID:12049647)
RGD PMID:12049647 PMID:21873635 MGI:2388220, RGD:13792537 NCBI chr10:87,098,330...87,102,465
Ensembl chr10:87,098,330...87,102,465
JBrowse link
G Tat tyrosine aminotransferase involved_in ISO
ISS
(PMID:7999802)
(MGI:5430853|PMID:21153519)
GO_REF:0000024
RGD
UniProt
PMID:7999802 PMID:21153519 GO_REF:0000024 MGI:5430853 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
ammonia assimilation cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3604881 (MGI:3604426|PMID:12559843)
Ensembl
RGD
PMID:12559843 GO_REF:0000107 MGI:3604426 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
JBrowse link
G Glul glutamate-ammonia ligase TAS
IDA
RGD PMID:1674354 PMID:28323 RGD:632694, RGD:2301547 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
arginine catabolic process to glutamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oat ornithine aminotransferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gls glutaminase involved_in IEA
ISO
IBA
ISS
GO_REF:0000107
(MGI:5320252|PMID:22228304)
PMID:21873635
GO_REF:0000024
(PMID:16899818), (PMID:22049910)
Ensembl
RGD
UniProt
PMID:16899818 PMID:22049910 PMID:22228304 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5320252, RGD:13792537 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Gls2 glutaminase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426
JBrowse link
G Glud1 glutamate dehydrogenase 1 involved_in ISO (PMID:11032875) RGD PMID:11032875 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:56,098,080...56,192,188
Ensembl chr 3:56,097,269...56,192,100
JBrowse link
glutamate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glud1 glutamate dehydrogenase 1 involved_in TAS
IBA
ISO
PMID:21873635
(PMID:11032875), (PMID:6121377)
RGD PMID:6121377 PMID:11032875 PMID:12684230 PMID:21873635 RGD:1601355, RGD:13792537 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
glutamate catabolic process to 2-oxoglutarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within IDA
ISO
(MGI:53641|PMID:4193185) RGD PMID:4193185 PMID:16489927 MGI:53641, RGD:13504861 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within IDA
ISO
(MGI:53641|PMID:4193185) RGD PMID:4193185 PMID:16489927 MGI:53641, RGD:13504861 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
glutamate catabolic process to aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) RGD PMID:4193185 MGI:53641 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) RGD PMID:4193185 MGI:53641 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
glutamate catabolic process via 2-oxoglutarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adhfe1 alcohol dehydrogenase, iron containing, 1 involved_in ISO
ISS
(PMID:16435184)
GO_REF:0000024
RGD
UniProt
PMID:16435184 GO_REF:0000024 NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517
JBrowse link
glutamate decarboxylation to succinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gad2 glutamate decarboxylase 2 IDA RGD PMID:8999827 RGD:1625237 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
JBrowse link
histidine catabolic process to glutamate and formamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amdhd1 amidohydrolase domain containing 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735
JBrowse link
G Hal histidine ammonia lyase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
G Uroc1 urocanate hydratase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:122,844,933...122,876,584
Ensembl chr 4:122,844,926...122,876,591
JBrowse link
histidine catabolic process to glutamate and formate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amdhd1 amidohydrolase domain containing 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735
JBrowse link
G Hal histidine ammonia lyase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
G Uroc1 urocanate hydratase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:122,844,933...122,876,584
Ensembl chr 4:122,844,926...122,876,591
JBrowse link
negative regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atcay ATCAY kinesin light chain interacting caytaxin involved_in ISO
ISS
(PMID:16899818)
GO_REF:0000024
RGD
UniProt
PMID:16899818 GO_REF:0000024 NCBI chr 7:8,487,763...8,511,527
Ensembl chr 7:8,487,763...8,512,663
JBrowse link
positive regulation of ammonia assimilation cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO
IEA
(MGI:5306122|PMID:21757002)
GO_REF:0000107
RGD
Ensembl
PMID:21757002 GO_REF:0000107 MGI:5306122 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
positive regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO (MGI:5306122|PMID:21757002) RGD PMID:21757002 MGI:5306122 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
proline catabolic process to glutamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:151,880,002...151,905,491 JBrowse link
G Iffo2 intermediate filament family orphan 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:151,831,503...151,873,075 JBrowse link
G Prodh1 proline dehydrogenase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305
JBrowse link
G Prodh2 proline dehydrogenase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:85,753,558...85,767,165
Ensembl chr 1:85,753,644...85,767,162
JBrowse link
G Tas1r2 taste 1 receptor member 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 5:151,909,648...151,925,345 JBrowse link
regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway IDA RGD PMID:19858196 RGD:6484536 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:3608695 (MGI:4948153|PMID:21490221), (MGI:5562570|PMID:24548853), (MGI:5616960|PMID:25429150) RGD PMID:21490221 PMID:24548853 PMID:25429150 MGI:4948153 MGI:5562570 MGI:5616960 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      primary metabolic process 10535
        cellular amino acid metabolic process 277
          alpha-amino acid metabolic process 199
            glutamine family amino acid metabolic process 74
              glutamate metabolic process 35
                D-glutamate metabolic process 0
                ammonia assimilation cycle + 3
                arginine catabolic process to glutamate 1
                glutamate biosynthetic process + 4
                glutamate catabolic process + 5
                histidine catabolic process to glutamate and formamide 4
                histidine catabolic process to glutamate and formate 4
                negative regulation of glutamate metabolic process + 1
                positive regulation of glutamate metabolic process + 1
                proline catabolic process to glutamate + 5
                regulation of glutamate metabolic process + 4
                tetrapyrrole biosynthetic process from glutamate + 0
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      cellular metabolic process 10719
        organic acid metabolic process 1013
          oxoacid metabolic process 982
            carboxylic acid metabolic process 961
              cellular amino acid metabolic process 277
                alpha-amino acid metabolic process 199
                  glutamine family amino acid metabolic process 74
                    glutamate metabolic process 35
                      D-glutamate metabolic process 0
                      ammonia assimilation cycle + 3
                      arginine catabolic process to glutamate 1
                      glutamate biosynthetic process + 4
                      glutamate catabolic process + 5
                      histidine catabolic process to glutamate and formamide 4
                      histidine catabolic process to glutamate and formate 4
                      negative regulation of glutamate metabolic process + 1
                      positive regulation of glutamate metabolic process + 1
                      proline catabolic process to glutamate + 5
                      regulation of glutamate metabolic process + 4
                      tetrapyrrole biosynthetic process from glutamate + 0
paths to the root