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ONTOLOGY REPORT - ANNOTATIONS

Term:glycoprotein catabolic process
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Accession:GO:0006516 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
Synonyms:exact_synonym: glycoprotein breakdown;   glycoprotein catabolism;   glycoprotein degradation


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glycoprotein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edem3 ER degradation enhancer, mannosidase alpha-like 3 acts_upstream_of_or_within IDA (PMID:16431915) MGI PMID:16431915 NCBI chr 1:151,631,099...151,698,079
Ensembl chr 1:151,631,122...151,697,802 		JBrowse link
G Fbxo17 F-box protein 17 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:28,416,176...28,437,570
Ensembl chr 7:28,416,229...28,437,569 		JBrowse link
G Fbxo2 F-box protein 2 involved_in
acts_upstream_of_or_within		 IDA
IBA		 (MGI:4821082|PMID:12140560)
(PMID:15723043)		 UniProt
MGI
GO_Central		 PMID:12140560 PMID:15723043 GO_REF:0000033 MGI:4821082 NCBI chr 4:148,244,605...148,250,874
Ensembl chr 4:148,245,078...148,250,881 		JBrowse link
G Fbxo27 F-box protein 27 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:28,392,205...28,398,763
Ensembl chr 7:28,392,274...28,398,763 		JBrowse link
G Fbxo44 F-box protein 44 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:148,237,256...148,244,663
Ensembl chr 4:148,237,257...148,244,939 		JBrowse link
G Fbxo6 F-box protein 6 acts_upstream_of_or_within
involved_in		 IDA
IBA		 (PMID:15723043) MGI
GO_Central		 PMID:15723043 GO_REF:0000033 NCBI chr 4:148,230,173...148,236,592
Ensembl chr 4:148,230,173...148,236,597 		JBrowse link
G Manba mannosidase, beta A, lysosomal involved_in
acts_upstream_of_or_within		 IDA
IBA		 (MGI:3615066|PMID:16377659)
(PMID:3447593)		 UniProt
GO_Central
MGI		 PMID:3447593 PMID:16377659 GO_REF:0000033 MGI:3615066 NCBI chr 3:135,191,367...135,277,165
Ensembl chr 3:135,191,372...135,277,165 		JBrowse link
G Nccrp1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:28,243,017...28,247,168
Ensembl chr 7:28,243,021...28,246,679 		JBrowse link
G Neu2 neuraminidase 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:87,501,749...87,525,567
Ensembl chr 1:87,437,611...87,525,567 		JBrowse link
G Neu4 sialidase 4 involved_in IDA
ISO		 (MGI:4361102|PMID:19506080), (MGI:5427293|PMID:22393058) UniProt
MGI		 PMID:19506080 PMID:22393058 GO_REF:0000119 MGI:4361102 MGI:4834177 MGI:5427293 NCBI chr 1:93,948,215...93,956,056
Ensembl chr 1:93,948,173...93,956,056 		JBrowse link
G Ngly1 N-glycanase 1 involved_in IDA
IBA
ISO		 (MGI:3054122|PMID:15358861) UniProt
GO_Central
MGI		 PMID:15358861 GO_REF:0000033 GO_REF:0000119 MGI:3054122 MGI:4834177 NCBI chr14:6,157,837...6,220,449
Ensembl chr14:6,157,837...6,220,483 		JBrowse link
G Stt3b STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:115,071,538...115,139,536
Ensembl chr 9:115,071,649...115,139,489 		JBrowse link
elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cela1 chymotrypsin-like elastase family, member 1 acts_upstream_of_or_within IMP (PMID:24793170) MGI PMID:24793170 NCBI chr15:100,572,303...100,585,801
Ensembl chr15:100,572,302...100,585,802 		JBrowse link
G Ctsl cathepsin L involved_in IMP (MGI:6259330|PMID:12417635) UniProt PMID:12417635 MGI:6259330 NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499 		JBrowse link
heparan sulfate proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpc1 glypican 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:92,759,367...92,787,933
Ensembl chr 1:92,759,367...92,788,501 		JBrowse link
G Gusb glucuronidase, beta involved_in IMP (PMID:11273777), (PMID:23897660) MGI PMID:11273777 PMID:23897660 NCBI chr 5:130,011,278...130,031,890
Ensembl chr 5:130,017,852...130,031,890 		JBrowse link
G Hgsnat heparan-alpha-glucosaminide N-acetyltransferase involved_in IGI (PMID:16960811) MGI PMID:16960811 NCBI chr 8:26,432,495...26,466,704
Ensembl chr 8:26,434,481...26,466,781 		JBrowse link
G Hpse heparanase involved_in ISO
IDA		 (PMID:12460766) MGI PMID:12460766 GO_REF:0000119 MGI:4834177 NCBI chr 5:100,827,350...100,867,582
Ensembl chr 5:100,827,350...100,867,582 		JBrowse link
G Ids iduronate 2-sulfatase involved_in IMP (PMID:17876721) MGI PMID:17876721 NCBI chr  X:69,386,675...69,429,437
Ensembl chr  X:69,386,675...69,408,690 		JBrowse link
G Idua iduronidase, alpha-L involved_in IMP (PMID:15979918)
(PMID:25854773)		 MGI PMID:15979918 PMID:25854773 NCBI chr 5:108,808,197...108,833,312
Ensembl chr 5:108,808,197...108,832,423 		JBrowse link
G Naglu alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) involved_in IMP (PMID:10588735) MGI PMID:10588735 NCBI chr11:100,960,918...100,968,483
Ensembl chr11:100,960,838...100,968,498 		JBrowse link
G Sgsh N-sulfoglucosamine sulfohydrolase (sulfamidase) involved_in ISO
IMP
IBA		 (PMID:11273777)
(PMID:10561464)		 MGI
GO_Central		 PMID:10561464 PMID:11273777 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:119,234,315...119,246,336
Ensembl chr11:119,234,251...119,246,362 		JBrowse link
mannoprotein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edem1 ER degradation enhancer, mannosidase alpha-like 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:108,800,984...108,836,317
Ensembl chr 6:108,805,602...108,836,317 		JBrowse link
G Edem2 ER degradation enhancer, mannosidase alpha-like 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:155,543,593...155,571,395
Ensembl chr 2:155,543,597...155,571,395 		JBrowse link
G Edem3 ER degradation enhancer, mannosidase alpha-like 3 involved_in IDA
ISO		 (MGI:3654428|PMID:16431915) ParkinsonsUK-UCL
MGI		 PMID:16431915 GO_REF:0000119 MGI:3654428 MGI:4834177 NCBI chr 1:151,631,099...151,698,079
Ensembl chr 1:151,631,122...151,697,802 		JBrowse link
G Man1b1 mannosidase, alpha, class 1B, member 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:25,222,742...25,242,225
Ensembl chr 2:25,222,350...25,242,224 		JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612 		JBrowse link
proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif 12 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:11,064,781...11,349,321
Ensembl chr15:11,064,876...11,349,317 		JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase involved_in ISO RGD
MGI		 PMID:32083858 GO_REF:0000096 MGI:4417868 RGD:151665122 NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    metabolic process 10995
      primary metabolic process 9507
        protein metabolic process 4150
          glycoprotein metabolic process 363
            glycoprotein catabolic process 29
              O-sialoglycoprotein catabolic process 0
              elastin catabolic process + 4
              mannoprotein catabolic process 4
              protein deglycosylation involved in glycoprotein catabolic process + 0
              proteoglycan catabolic process + 10
              ubiquitin-dependent glycoprotein ERAD pathway + 0
Path 2
Term Annotations click to browse term
  biological_process 28573
    metabolic process 10995
      organic substance metabolic process 10563
        macromolecule metabolic process 8847
          macromolecule catabolic process 1543
            protein catabolic process 1037
              glycoprotein catabolic process 29
                O-sialoglycoprotein catabolic process 0
                elastin catabolic process + 4
                mannoprotein catabolic process 4
                protein deglycosylation involved in glycoprotein catabolic process + 0
                proteoglycan catabolic process + 10
                ubiquitin-dependent glycoprotein ERAD pathway + 0
paths to the root