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ONTOLOGY REPORT - ANNOTATIONS


Term:glycoprotein catabolic process
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Accession:GO:0006516 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
Synonyms:exact_synonym: glycoprotein breakdown;   glycoprotein catabolism;   glycoprotein degradation


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glycoprotein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 acts_upstream_of_or_within ISO (MGI:3654428|PMID:16431915) MGI PMID:16431915 MGI:3654428 NCBI chrNW_004955406:23,329,400...23,401,282
Ensembl chrNW_004955406:23,329,400...23,401,281
JBrowse link
G Fbxo2 F-box protein 2 acts_upstream_of_or_within
involved_in
ISO (MGI:3573989|PMID:15723043)
(MGI:4821082|PMID:12140560)
MGI
UniProt
PMID:12140560 PMID:15723043 MGI:3573989 MGI:4821082 NCBI chrNW_004955486:2,212,001...2,217,260
Ensembl chrNW_004955486:2,212,001...2,218,017
JBrowse link
G Fbxo6 F-box protein 6 acts_upstream_of_or_within ISO (MGI:3573989|PMID:15723043) MGI PMID:15723043 MGI:3573989 NCBI chrNW_004955486:2,197,296...2,205,947
Ensembl chrNW_004955486:2,197,467...2,201,256
JBrowse link
G Manba mannosidase beta involved_in
acts_upstream_of_or_within
ISO (MGI:3615066|PMID:16377659)
(MGI:57603|PMID:3447593)
UniProt
MGI
PMID:3447593 PMID:16377659 MGI:3615066 MGI:57603 NCBI chrNW_004955496:5,744,374...5,837,974
Ensembl chrNW_004955496:5,744,250...5,841,293
JBrowse link
G Neu2 neuraminidase 2 involved_in ISO (PMID:14613940) UniProt PMID:14613940 NCBI chrNW_004955453:3,054,626...3,063,070
Ensembl chrNW_004955453:3,052,297...3,061,791
JBrowse link
G Neu4 neuraminidase 4 involved_in ISO (PMID:15213228), (PMID:15847605)
(MGI:4361102|PMID:19506080), (MGI:5427293|PMID:22393058)
UniProt PMID:15213228 PMID:15847605 PMID:19506080 PMID:22393058 MGI:4361102 MGI:5427293 NCBI chrNW_004955542:66,214...70,456
Ensembl chrNW_004955542:66,174...71,058
JBrowse link
G Ngly1 N-glycanase 1 involved_in ISO (PMID:15358861)
(MGI:3054122|PMID:15358861)
UniProt PMID:15358861 MGI:3054122 NCBI chrNW_004955430:17,564,319...17,645,564
Ensembl chrNW_004955430:17,564,319...17,645,564
JBrowse link
G Stt3b STT3 oligosaccharyltransferase complex catalytic subunit B involved_in ISO (PMID:22607976) UniProt PMID:22607976 NCBI chrNW_004955430:22,986,673...23,070,923
Ensembl chrNW_004955430:22,986,762...23,069,383
JBrowse link
elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cela1 chymotrypsin like elastase 1 acts_upstream_of_or_within ISO (MGI:5641427|PMID:24793170) MGI PMID:24793170 MGI:5641427 NCBI chrNW_004955547:1,810,680...1,823,938
Ensembl chrNW_004955547:1,810,670...1,824,409
JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in ISO (PMID:29101312) ARUK-UCL PMID:29101312 NCBI chrNW_004955412:6,045,146...6,057,112
Ensembl chrNW_004955412:6,045,100...6,057,262
JBrowse link
heparan sulfate proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpc1 glypican 1 involved_in ISO (PMID:12732622) UniProt PMID:12732622 NCBI chrNW_004955542:947,556...968,295
Ensembl chrNW_004955542:947,556...968,295
JBrowse link
G Gusb glucuronidase beta involved_in ISO (MGI:7281718|PMID:23897660), (MGI:7284274|PMID:11273777) MGI PMID:11273777 PMID:23897660 MGI:7281718 MGI:7284274 NCBI chrNW_004955456:8,377,161...8,392,298
Ensembl chrNW_004955456:8,378,654...8,392,252
JBrowse link
G Hgsnat heparan-alpha-glucosaminide N-acetyltransferase involved_in ISO (MGI:3703408|PMID:16960811) MGI PMID:16960811 MGI:3703408 NCBI chrNW_004955457:13,351,963...13,386,521
Ensembl chrNW_004955457:13,349,213...13,387,251
JBrowse link
G Hpse heparanase involved_in ISO (PMID:12213822)
(MGI:2449691|PMID:12460766)
UniProt
MGI
PMID:12213822 PMID:12460766 MGI:2449691 NCBI chrNW_004955474:6,367,467...6,394,395
Ensembl chrNW_004955474:6,367,467...6,394,395
JBrowse link
G Ids iduronate 2-sulfatase involved_in ISO (MGI:6140076|PMID:17876721) MGI PMID:17876721 MGI:6140076 NCBI chrNW_004955498:1,863,002...1,886,720
Ensembl chrNW_004955498:1,860,628...1,886,867
JBrowse link
G Idua alpha-L-iduronidase involved_in ISO (MGI:3605936|PMID:15979918)
(MGI:7310026|PMID:25854773)
MGI PMID:15979918 PMID:25854773 MGI:3605936 MGI:7310026 NCBI chrNW_004955514:474,830...488,007
Ensembl chrNW_004955514:475,731...488,007
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase involved_in ISO (MGI:1350713|PMID:10588735) MGI PMID:10588735 MGI:1350713 NCBI chrNW_004955451:16,445,338...16,449,243
Ensembl chrNW_004955451:16,445,338...16,450,062
JBrowse link
G Sgsh N-sulfoglucosamine sulfohydrolase involved_in ISO (PMID:15146460)
(MGI:7284274|PMID:11273777)
(MGI:2151820|PMID:10561464)
UniProt
MGI
PMID:10561464 PMID:11273777 PMID:15146460 MGI:2151820 MGI:7284274 NCBI chrNW_004955506:2,701,901...2,713,431
Ensembl chrNW_004955506:2,701,905...2,711,073
JBrowse link
mannose trimming involved in glycoprotein ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 involved_in ISO (PMID:25092655) ParkinsonsUK-UCL PMID:25092655 NCBI chrNW_004955421:8,196,631...8,225,561
Ensembl chrNW_004955421:8,196,557...8,225,561
JBrowse link
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 involved_in ISO (PMID:25092655) ParkinsonsUK-UCL PMID:25092655 NCBI chrNW_004955422:26,243,034...26,271,849
Ensembl chrNW_004955422:26,242,986...26,273,297
JBrowse link
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 involved_in ISO (PMID:25092655)
(MGI:3654428|PMID:16431915)
ParkinsonsUK-UCL PMID:16431915 PMID:25092655 MGI:3654428 NCBI chrNW_004955406:23,329,400...23,401,282
Ensembl chrNW_004955406:23,329,400...23,401,281
JBrowse link
G Man1a1 mannosidase alpha class 1A member 1 involved_in ISO (PMID:27108681) UniProt PMID:27108681 NCBI chrNW_004955436:1,830,275...1,972,861
Ensembl chrNW_004955436:1,830,211...1,935,970
JBrowse link
G Man1b1 mannosidase alpha class 1B member 1 involved_in ISO (PMID:18003979), (PMID:21062743) ParkinsonsUK-UCL PMID:18003979 PMID:21062743 NCBI chrNW_004955513:5,109,651...5,122,568
Ensembl chrNW_004955513:5,111,046...5,122,442
JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO (PMID:10545518) BHF-UCL PMID:10545518 NCBI chrNW_004955415:30,507,972...30,512,109 JBrowse link
proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif 12 involved_in ISO (PMID:17895370) BHF-UCL PMID:17895370 NCBI chrNW_004955426:19,146,288...19,471,880
Ensembl chrNW_004955426:19,150,343...19,471,534
JBrowse link
G Btk Bruton tyrosine kinase ISO RGD PMID:32083858 RGD:151665122 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120
JBrowse link
ubiquitin-dependent glycoprotein ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 involved_in ISO (PMID:21062743), (PMID:25092655) ParkinsonsUK-UCL PMID:21062743 PMID:25092655 NCBI chrNW_004955421:8,196,631...8,225,561
Ensembl chrNW_004955421:8,196,557...8,225,561
JBrowse link
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 involved_in ISO (PMID:15537790) ParkinsonsUK-UCL PMID:15537790 NCBI chrNW_004955422:26,243,034...26,271,849
Ensembl chrNW_004955422:26,242,986...26,273,297
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 12334
    metabolic process 7839
      organic substance metabolic process 7548
        macromolecule metabolic process 6197
          macromolecule catabolic process 789
            glycoprotein catabolic process 25
              O-sialoglycoprotein catabolic process 0
              elastin catabolic process + 3
              mannoprotein catabolic process 0
              protein deglycosylation involved in glycoprotein catabolic process + 5
              proteoglycan catabolic process + 10
              ubiquitin-dependent glycoprotein ERAD pathway + 5
paths to the root