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ONTOLOGY REPORT - ANNOTATIONS


Term:glycoprotein catabolic process
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Accession:GO:0006516 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
Synonyms:exact_synonym: glycoprotein breakdown;   glycoprotein catabolism;   glycoprotein degradation



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glycoprotein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 acts_upstream_of_or_within ISO (MGI:3654428|PMID:16431915) RGD PMID:16431915 MGI:3654428 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523
JBrowse link
G Fbxo17 F-box protein 17 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:84,002,276...84,024,455
Ensembl chr 1:84,002,267...84,024,453
JBrowse link
G Fbxo2 F-box protein 2 involved_in
acts_upstream_of_or_within
ISO
IBA
(MGI:4821082|PMID:12140560)
PMID:21873635
(MGI:3573989|PMID:15723043)
RGD PMID:12140560 PMID:15723043 PMID:21873635 MGI:3573989 MGI:4821082, RGD:13792537 NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355
JBrowse link
G Fbxo27 F-box protein 27 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,965,426...83,987,781
Ensembl chr 1:83,965,986...83,987,778
JBrowse link
G Fbxo44 F-box protein 44 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:158,583,363...158,592,510
Ensembl chr 5:158,583,366...158,592,363
JBrowse link
G Fbxo6 F-box protein 6 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3573989|PMID:15723043)
RGD PMID:15723043 PMID:21873635 MGI:3573989, RGD:13792537 NCBI chr 5:158,576,729...158,582,520
Ensembl chr 5:158,576,759...158,582,525
JBrowse link
G Manba mannosidase beta involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
GO_REF:0000024
(MGI:3615066|PMID:16377659)
(MGI:57603|PMID:3447593)
PMID:21873635
UniProt
RGD
PMID:3447593 PMID:16377659 PMID:21873635 GO_REF:0000024 MGI:3615066 MGI:57603, RGD:13792537 NCBI chr 2:223,910,432...224,002,988
Ensembl chr 2:223,910,432...224,002,983
JBrowse link
G Nccrp1 NCCRP1, F-box associated domain containing involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,835,083...83,838,620
Ensembl chr 1:83,835,083...83,838,676
JBrowse link
G Neu2 neuraminidase 2 involved_in ISO (PMID:14613940) RGD PMID:14613940 NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:88,249,135...88,267,355
JBrowse link
G Neu4 neuraminidase 4 involved_in ISO (PMID:15213228), (PMID:15847605)
(MGI:4361102|PMID:19506080), (MGI:5427293|PMID:22393058)
RGD PMID:15213228 PMID:15847605 PMID:19506080 PMID:22393058 MGI:4361102 MGI:5427293 NCBI chr 9:94,396,920...94,402,576
Ensembl chr 9:94,396,920...94,402,576
JBrowse link
G Ngly1 N-glycanase 1 involved_in ISO
IBA
IEA
ISS
(PMID:15358861)
PMID:21873635
GO_REF:0000002
(MGI:3054122|PMID:15358861)
GO_REF:0000024
RGD
InterPro
UniProt
PMID:15358861 PMID:21873635 GO_REF:0000002 GO_REF:0000024 MGI:3054122, RGD:13792537 NCBI chr15:9,153,738...9,210,228
Ensembl chr15:9,153,738...9,204,630
JBrowse link
G Stt3b STT3 oligosaccharyltransferase complex catalytic subunit B involved_in ISO (PMID:22607976) RGD PMID:22607976 NCBI chr 8:114,928,678...114,994,027
Ensembl chr 8:114,917,824...114,994,028
JBrowse link
elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cela1 chymotrypsin like elastase 1 acts_upstream_of_or_within ISO (MGI:5641427|PMID:24793170) RGD PMID:24793170 MGI:5641427 NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285
JBrowse link
G Ctsl cathepsin L involved_in ISS
ISO
GO_REF:0000024
(MGI:6259330|PMID:12417635)
UniProt
RGD
PMID:12417635 GO_REF:0000024 MGI:6259330 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in ISO
IEA
(PMID:29101312)
GO_REF:0000107
RGD
Ensembl
PMID:29101312 GO_REF:0000107 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
heparan sulfate proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpc1 glypican 1 involved_in ISO
ISS
IEA
(PMID:12732622)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:12732622 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047
JBrowse link
G Gusb glucuronidase, beta involved_in ISO MGI:1856041 (MGI:7281718|PMID:23897660), (MGI:7284274|PMID:11273777) RGD PMID:11273777 PMID:23897660 MGI:7281718 MGI:7284274 NCBI chr12:26,701,191...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G Hgsnat heparan-alpha-glucosaminide N-acetyltransferase involved_in ISO UniProtKB:Q68CP4 (MGI:3703408|PMID:16960811) RGD PMID:16960811 MGI:3703408 NCBI chr16:66,105,233...66,137,444
Ensembl chr16:66,105,181...66,136,138
JBrowse link
G Hpse heparanase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:2449691|PMID:12460766)
(PMID:12213822)
UniProt
Ensembl
RGD
PMID:12213822 PMID:12460766 GO_REF:0000024 GO_REF:0000107 MGI:2449691 NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010
JBrowse link
G Ids iduronate 2-sulfatase involved_in ISO MGI:3625122 (MGI:6140076|PMID:17876721) RGD PMID:17876721 MGI:6140076 NCBI chr  X:149,025,977...149,046,639
Ensembl chr  X:149,025,976...149,046,663
JBrowse link
G Idua alpha-L-iduronidase involved_in ISO MGI:2176236|MGI:2651471 (MGI:3605936|PMID:15979918), (MGI:7310026|PMID:25854773) RGD PMID:15979918 PMID:25854773 MGI:3605936 MGI:7310026 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase involved_in ISO MGI:1934018 (MGI:1350713|PMID:10588735) RGD PMID:10588735 MGI:1350713 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972
JBrowse link
G Sgsh N-sulfoglucosamine sulfohydrolase involved_in ISO (PMID:15146460)
MGI:1856041|MGI:2151181 (MGI:2151820|PMID:10561464), (MGI:7284274|PMID:11273777)
RGD PMID:10561464 PMID:11273777 PMID:15146460 MGI:2151820 MGI:7284274 NCBI chr10:104,596,810...104,613,510
Ensembl chr10:104,598,112...104,613,486
JBrowse link
mannose trimming involved in glycoprotein ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 involved_in ISO (PMID:25092655) RGD PMID:25092655 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
JBrowse link
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 involved_in ISO (PMID:25092655) RGD PMID:25092655 NCBI chr 3:144,201,604...144,227,423
Ensembl chr 3:144,201,605...144,227,485
JBrowse link
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 involved_in ISO (PMID:25092655)
(MGI:3654428|PMID:16431915)
RGD PMID:16431915 PMID:25092655 MGI:3654428 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523
JBrowse link
G Man1a1 mannosidase, alpha, class 1A, member 1 involved_in ISO (PMID:27108681) RGD PMID:27108681 NCBI chr20:33,202,509...33,385,747
Ensembl chr20:33,202,517...33,385,824
JBrowse link
G Man1b1 mannosidase, alpha, class 1B, member 1 involved_in ISO (PMID:18003979), (PMID:21062743) RGD PMID:18003979 PMID:21062743 NCBI chr 3:8,143,877...8,165,007
Ensembl chr 3:8,143,381...8,165,006
JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO (PMID:10545518) RGD PMID:10545518 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO (PMID:17895370) RGD PMID:17895370 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629
JBrowse link
G Btk Bruton tyrosine kinase IMP RGD PMID:32083858 RGD:151665122 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
ubiquitin-dependent glycoprotein ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 involved_in ISO (PMID:21062743), (PMID:25092655) RGD PMID:21062743 PMID:25092655 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
JBrowse link
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 involved_in ISO (PMID:15537790) RGD PMID:15537790 NCBI chr 3:144,201,604...144,227,423
Ensembl chr 3:144,201,605...144,227,485
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19746
    metabolic process 12044
      primary metabolic process 10824
        protein metabolic process 5951
          glycoprotein metabolic process 396
            glycoprotein catabolic process 30
              O-sialoglycoprotein catabolic process 0
              elastin catabolic process + 4
              mannoprotein catabolic process 0
              protein deglycosylation involved in glycoprotein catabolic process + 5
              proteoglycan catabolic process + 10
              ubiquitin-dependent glycoprotein ERAD pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 19746
    metabolic process 12044
      organic substance metabolic process 11597
        macromolecule metabolic process 9959
          protein metabolic process 5951
            glycoprotein metabolic process 396
              glycoprotein catabolic process 30
                O-sialoglycoprotein catabolic process 0
                elastin catabolic process + 4
                mannoprotein catabolic process 0
                protein deglycosylation involved in glycoprotein catabolic process + 5
                proteoglycan catabolic process + 10
                ubiquitin-dependent glycoprotein ERAD pathway + 5
paths to the root