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ONTOLOGY REPORT - ANNOTATIONS


Term:ubiquitin-dependent protein catabolic process
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Accession:GO:0006511 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
Synonyms:exact_synonym: ubiquitin-dependent protein breakdown;   ubiquitin-dependent protein catabolism;   ubiquitin-dependent protein degradation;   ubiquitin-dependent proteolysis
 narrow_synonym: myofibrillar protein ubiquitination during ubiquitin-dependent protein breakdown;   myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process;   myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolism;   myofibrillar protein ubiquitination during ubiquitin-dependent protein degradation;   protein ubiquitination during ubiquitin-dependent protein breakdown;   protein ubiquitination during ubiquitin-dependent protein catabolism;   protein ubiquitination during ubiquitin-dependent protein degradation;   protein ubiquitinylation during ubiquitin-dependent protein catabolic process;   protein ubiquitinylation during ubiquitin-dependent protein catabolism;   protein ubiquitylation during ubiquitin-dependent protein catabolic process;   protein ubiquitylation during ubiquitin-dependent protein catabolism
 broad_synonym: protein degradation tagging activity
 related_synonym: protein ubiquitination during ubiquitin-dependent protein catabolic process;   protein ubiquitination involved in ubiquitin-dependent protein catabolic process
 alt_id: GO:0042787;   GO:0043432


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ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AMFR autocrine motility factor receptor JBrowse link 16 36,647,792 36,711,782 RGD:9068941
G AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 JBrowse link 14 55,213,600 55,265,198 RGD:9068941
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 JBrowse link 15 51,423,132 51,534,278 RGD:9068941
G ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 JBrowse link 3 48,844,161 48,910,183 RGD:9068941
G ARRB1 arrestin beta 1 JBrowse link 11 70,319,935 70,411,276 RGD:9068941
G ARRDC1 arrestin domain containing 1 JBrowse link 9 108,711,276 108,720,942 RGD:9068941
G ARRDC4 arrestin domain containing 4 JBrowse link 15 76,643,796 76,657,525 RGD:9068941
G ASB2 ankyrin repeat and SOCS box containing 2 JBrowse link 14 74,566,607 74,608,905 RGD:9068941
G ATXN3 ataxin 3 JBrowse link 14 72,693,446 72,741,772 RGD:9068941
G BAG6 BAG cochaperone 6 JBrowse link 6 31,300,126 31,313,829 RGD:9068941
G BFAR bifunctional apoptosis regulator JBrowse link 16 13,558,912 13,597,023 RGD:9068941
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase JBrowse link 10 97,958,527 98,159,550 RGD:9068941
G CBL Cbl proto-oncogene JBrowse link 11 114,044,996 114,149,204 RGD:9068941
G CBLC Cbl proto-oncogene C JBrowse link 19 41,726,272 41,748,829 RGD:9068941
G CNOT4 CCR4-NOT transcription complex subunit 4 JBrowse link 7 127,327,092 127,475,213 RGD:9068941
G CUL3 cullin 3 JBrowse link 2B 111,714,533 111,827,080 RGD:9068941
G CUL4A cullin 4A JBrowse link 13 94,350,484 94,409,183 RGD:9068941
G DCST1 DC-STAMP domain containing 1 JBrowse link 1 130,381,851 130,398,975 RGD:9068941
G DDB1 damage specific DNA binding protein 1 JBrowse link 11 56,599,422 56,633,140 RGD:9068941
G DTL denticleless E3 ubiquitin protein ligase homolog JBrowse link 1 187,603,600 187,672,006 RGD:9068941
G DTX3L deltex E3 ubiquitin ligase 3L JBrowse link 3 119,654,019 119,664,918 RGD:9068941
G FBXL14 F-box and leucine rich repeat protein 14 JBrowse link 12 1,674,046 1,703,414 RGD:9068941
G FBXL2 F-box and leucine rich repeat protein 2 JBrowse link 3 33,199,436 33,308,831 RGD:9068941
G FBXO10 F-box protein 10 JBrowse link 9 37,355,861 37,421,321 RGD:9068941
G FBXO2 F-box protein 2 JBrowse link 1 10,408,853 10,415,174 RGD:9068941
G FBXO4 F-box protein 4 JBrowse link 5 68,336,673 68,474,481 RGD:9068941
G FBXO45 F-box protein 45 JBrowse link 3 193,913,712 193,934,123 RGD:9068941
G FBXO7 F-box protein 7 JBrowse link 22 13,481,255 13,505,301 RGD:9068941
G FBXO8 F-box protein 8 JBrowse link 4 166,462,626 166,509,875 RGD:9068941
G HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 JBrowse link 6 102,541,992 102,674,281 RGD:9068941
G HDAC6 histone deacetylase 6 JBrowse link X 41,099,539 41,122,650 RGD:9068941
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 16 37,210,170 37,221,961 RGD:9068941
G ITCH itchy E3 ubiquitin protein ligase JBrowse link 20 30,690,172 30,840,504 RGD:9068941
G KCTD10 potassium channel tetramerization domain containing 10 JBrowse link 12 107,025,380 107,054,118 RGD:9068941
G KCTD21 potassium channel tetramerization domain containing 21 JBrowse link 11 73,231,381 73,248,796 RGD:9068941
G KCTD6 potassium channel tetramerization domain containing 6 JBrowse link 3 58,365,847 58,439,763 RGD:9068941
G KEAP1 kelch like ECH associated protein 1 JBrowse link 19 10,037,544 10,055,091 RGD:9068941
G KLHL15 kelch like family member 15 JBrowse link X 16,583,117 16,625,029 RGD:9068941
G KLHL25 kelch like family member 25 JBrowse link 15 64,448,130 64,486,254 RGD:9068941
G KLHL3 kelch like family member 3 JBrowse link 5 133,005,563 133,276,087 RGD:9068941
G KLHL8 kelch like family member 8 JBrowse link 4 79,462,540 79,522,547 RGD:9068941
G LNX1 ligand of numb-protein X 1 JBrowse link 4 70,374,106 70,497,058 RGD:9068941
G LOC100974874 E3 ubiquitin-protein ligase CHFR JBrowse link 12 130,201,704 130,247,891 RGD:9068941
G LOC100984949 F-box/LRR-repeat protein 12 JBrowse link 19 9,362,764 9,371,547 RGD:9068941
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 5 57,116,405 57,197,017 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 12 66,322,340 66,357,010 RGD:9068941
G MIB1 mindbomb E3 ubiquitin protein ligase 1 JBrowse link 18 14,944,432 15,113,313 RGD:9068941
G MYLIP myosin regulatory light chain interacting protein JBrowse link 6 15,985,844 16,005,043 RGD:9068941
G NEDD4 NEDD4 E3 ubiquitin protein ligase JBrowse link 15 34,798,880 34,963,823 RGD:9068941
G NEDD4L NEDD4 like E3 ubiquitin protein ligase JBrowse link 18 51,428,077 51,792,995 RGD:9068941
G NPLOC4 NPL4 homolog, ubiquitin recognition factor JBrowse link 17 76,012,756 76,092,901 RGD:9068941
G NTAN1 N-terminal asparagine amidase JBrowse link 16 13,704,891 13,722,531 RGD:9068941
G NUB1 negative regulator of ubiquitin like proteins 1 JBrowse link 7 142,927,730 142,964,475 RGD:9068941
G OS9 OS9 endoplasmic reticulum lectin JBrowse link 12 31,205,239 31,232,769 RGD:9068941
G PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 JBrowse link 6 29,844,971 29,851,792 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 6 159,293,016 160,679,106 RGD:9068941
G PSMC2 proteasome 26S subunit, ATPase 2 JBrowse link 7 95,338,743 95,359,353 RGD:9068941
G PSMD11 proteasome 26S subunit, non-ATPase 11 JBrowse link 17 24,292,990 24,331,690 RGD:9068941
G PSMF1 proteasome inhibitor subunit 1 JBrowse link 20 1,275,662 1,325,410 RGD:9068941
G RBBP6 RB binding protein 6, ubiquitin ligase RGD:9068941
G RCHY1 ring finger and CHY zinc finger domain containing 1 JBrowse link 4 48,691,213 48,725,979 RGD:9068941
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase JBrowse link 17 21,696,808 21,779,878 RGD:9068941
G RLIM ring finger protein, LIM domain interacting JBrowse link X 63,834,345 63,865,874 RGD:9068941
G RNF11 ring finger protein 11 JBrowse link 1 50,480,862 50,517,676 RGD:9068941
G RNF125 ring finger protein 125 JBrowse link 18 25,227,353 25,297,186 RGD:9068941
G RNF144B ring finger protein 144B JBrowse link 6 18,124,935 18,316,842 RGD:9068941
G RNF146 ring finger protein 146 JBrowse link 6 125,057,312 125,079,096 RGD:9068941
G RNF168 ring finger protein 168 JBrowse link 3 193,814,785 193,848,620 RGD:9068941
G RNF20 ring finger protein 20 JBrowse link 9 72,738,132 72,767,868 RGD:9068941
G RNF213 ring finger protein 213 JBrowse link 17 74,688,130 74,823,973 RGD:9068941
G RNF34 ring finger protein 34 JBrowse link 12 118,998,436 119,022,823 RGD:9068941
G RNF40 ring finger protein 40 JBrowse link 16 24,194,293 24,207,460 RGD:9068941
G RNF43 ring finger protein 43 JBrowse link 17 52,420,516 52,492,813 RGD:9068941
G RNF6 ring finger protein 6 JBrowse link 13 7,505,669 7,515,542 RGD:9068941
G RNF8 ring finger protein 8 JBrowse link 6 36,918,705 36,955,380 RGD:9068941
G SIAH1 siah E3 ubiquitin protein ligase 1 JBrowse link 16 28,627,021 28,651,343 RGD:9068941
G SIAH2 siah E3 ubiquitin protein ligase 2 JBrowse link 3 147,759,375 147,781,639 RGD:9068941
G SKP2 S-phase kinase associated protein 2 JBrowse link 5 74,179,608 74,211,563 RGD:9068941
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 JBrowse link 7 90,995,923 91,112,240 RGD:9068941
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 JBrowse link 17 58,638,995 58,759,443 RGD:9068941
G SPOP speckle type BTB/POZ protein JBrowse link 17 43,685,913 43,765,277 RGD:9068941
G SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 JBrowse link 1 8,053,596 8,132,143 RGD:9068941
G SPSB2 splA/ryanodine receptor domain and SOCS box containing 2 JBrowse link 12 7,002,783 7,005,365 RGD:9068941
G SPSB4 splA/ryanodine receptor domain and SOCS box containing 4 JBrowse link 3 138,085,136 138,181,747 RGD:9068941
G STUB1 STIP1 homology and U-box containing protein 1 RGD:9068941
G SYVN1 synoviolin 1 JBrowse link 11 60,489,626 60,496,945 RGD:9068941
G TAF1 TATA-box binding protein associated factor 1 JBrowse link X 60,630,137 60,729,904 RGD:9068941
G TOPORS TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase JBrowse link 9 32,314,850 32,327,067 RGD:9068941
G TP53INP2 tumor protein p53 inducible nuclear protein 2 JBrowse link 20 31,033,855 31,042,976 RGD:9068941
G TRIM25 tripartite motif containing 25 JBrowse link 17 50,965,592 50,991,630 RGD:9068941
G TRIM32 tripartite motif containing 32 JBrowse link 9 87,819,723 87,838,684 RGD:9068941
G TRIP12 thyroid hormone receptor interactor 12 JBrowse link 2B 117,013,343 117,175,296 RGD:9068941
G TRPC4AP transient receptor potential cation channel subfamily C member 4 associated protein JBrowse link 20 31,330,860 31,420,662 RGD:9068941
G TTC3 tetratricopeptide repeat domain 3 JBrowse link 21 23,435,041 23,564,416 RGD:9068941
G UBA6 ubiquitin like modifier activating enzyme 6 JBrowse link 4 56,348,370 56,433,433 RGD:9068941
G UBD ubiquitin D JBrowse link 6 29,359,680 29,364,014 RGD:9068941
G UBE2B ubiquitin conjugating enzyme E2 B JBrowse link 5 129,775,011 129,794,853 RGD:9068941
G UBE2C ubiquitin conjugating enzyme E2 C JBrowse link 20 42,152,219 42,156,246 RGD:9068941
G UBE2D1 ubiquitin conjugating enzyme E2 D1 JBrowse link 10 54,867,346 54,903,125 RGD:9068941
G UBE2D3 ubiquitin conjugating enzyme E2 D3 JBrowse link 4 95,218,319 95,293,053 RGD:9068941
G UBE2L3 ubiquitin conjugating enzyme E2 L3 JBrowse link 22 3,690,100 3,746,665 RGD:9068941
G UBE2N ubiquitin conjugating enzyme E2 N JBrowse link 12 90,951,446 90,984,075 RGD:9068941
G UBE2Z ubiquitin conjugating enzyme E2 Z JBrowse link 17 8,611,033 8,631,716 RGD:9068941
G UBE3A ubiquitin protein ligase E3A JBrowse link 15 4,494,029 4,595,415 RGD:9068941
G UBE4B ubiquitination factor E4B JBrowse link 1 8,801,707 8,949,465 RGD:9068941
G UBR1 ubiquitin protein ligase E3 component n-recognin 1 JBrowse link 15 21,899,611 22,064,606 RGD:9068941
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 JBrowse link 6 42,150,409 42,282,486 RGD:9068941
G UBR3 ubiquitin protein ligase E3 component n-recognin 3 JBrowse link 2B 57,099,882 57,366,981 RGD:9068941
G UBR4 ubiquitin protein ligase E3 component n-recognin 4 JBrowse link 1 18,032,528 18,168,954 RGD:9068941
G UCHL1 ubiquitin C-terminal hydrolase L1 JBrowse link 4 35,580,755 35,592,314 RGD:9068941
G UFD1 ubiquitin recognition factor in ER associated degradation 1 JBrowse link 22 2,209,590 2,238,449 RGD:9068941
G UHRF1 ubiquitin like with PHD and ring finger domains 1 JBrowse link 19 3,926,583 3,979,163 RGD:9068941
G VCP valosin containing protein JBrowse link 9 34,907,147 34,923,227 RGD:9068941
G WDR81 WD repeat domain 81 JBrowse link 17 1,708,119 1,722,405 RGD:9068941
G WDR91 WD repeat domain 91 JBrowse link 7 127,150,041 127,176,376 RGD:9068941
G XBP1 X-box binding protein 1 JBrowse link 22 9,863,479 9,869,491 RGD:9068941
G ZNRF3 zinc and ring finger 3 JBrowse link 22 9,891,021 10,109,147 RGD:9068941
G ZNRF4 zinc and ring finger 4 JBrowse link 19 4,474,001 4,475,435 RGD:9068941
anaphase-promoting complex-dependent catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CDC20 cell division cycle 20 JBrowse link 1 42,660,338 42,664,618 RGD:9068941
G CUL3 cullin 3 JBrowse link 2B 111,714,533 111,827,080 RGD:9068941
G ECRG4 ECRG4 augurin precursor JBrowse link 2A 95,762,149 95,774,834 RGD:9068941
G FBXO31 F-box protein 31 JBrowse link 16 67,997,481 68,053,081 RGD:9068941
G FZR1 fizzy and cell division cycle 20 related 1 JBrowse link 19 2,533,172 2,564,301 RGD:9068941
G UBE2C ubiquitin conjugating enzyme E2 C JBrowse link 20 42,152,219 42,156,246 RGD:9068941
G UBE2S ubiquitin conjugating enzyme E2 S JBrowse link 19 52,444,270 52,450,770 RGD:9068941
mannose trimming involved in glycoprotein ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 3 5,133,927 5,162,485 RGD:9068941
G EDEM2 ER degradation enhancing alpha-mannosidase like protein 2 JBrowse link 20 31,443,590 31,475,430 RGD:9068941
G EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 JBrowse link 1 160,217,526 160,281,785 RGD:9068941
G MAN1B1 mannosidase alpha class 1B member 1 JBrowse link 9 108,148,020 108,168,931 RGD:9068941
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SGTA small glutamine rich tetratricopeptide repeat containing alpha JBrowse link 19 1,778,728 1,808,199 RGD:9068941
G SVIP small VCP interacting protein JBrowse link 11 22,828,321 22,837,536 RGD:9068941
G USP14 ubiquitin specific peptidase 14 JBrowse link 18 14,104,754 14,158,402 RGD:9068941
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BAG5 BAG cochaperone 5 JBrowse link 14 84,182,879 84,189,180 RGD:9068941
G BAG6 BAG cochaperone 6 JBrowse link 6 31,300,126 31,313,829 RGD:9068941
G CAMLG calcium modulating ligand JBrowse link 5 130,138,644 130,144,540 RGD:9068941
G CCAR2 cell cycle and apoptosis regulator 2 JBrowse link 8 21,854,803 21,870,556 RGD:9068941
G CLEC16A C-type lectin domain containing 16A JBrowse link 16 9,887,877 10,124,500 RGD:9068941
G DDRGK1 DDRGK domain containing 1 JBrowse link 20 3,276,292 3,290,433 RGD:9068941
G FHIT fragile histidine triad diadenosine triphosphatase JBrowse link 3 59,670,777 61,177,974 RGD:9068941
G GIPC1 GIPC PDZ domain containing family member 1 JBrowse link 19 14,041,192 14,059,402 RGD:9068941
G HSP90AB1 heat shock protein 90 alpha family class B member 1 JBrowse link 6 43,842,796 43,849,637 RGD:9068941
G KLHL40 kelch like family member 40 JBrowse link 3 42,592,977 42,600,100 RGD:9068941
G MAP1A microtubule associated protein 1A JBrowse link 15 22,472,641 22,493,293 RGD:9068941
G MTM1 myotubularin 1 JBrowse link X 140,218,742 140,323,495 RGD:9068941
G N4BP1 NEDD4 binding protein 1 JBrowse link 16 28,809,881 28,881,352 RGD:9068941
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 19 44,739,739 44,751,303 RGD:9068941
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 60,798,219 60,840,948 RGD:9068941
G PANO1 proapoptotic nucleolar protein 1 JBrowse link 11 814,040 816,633 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 1 6,722,260 6,745,915 RGD:9068941
G PBK PDZ binding kinase JBrowse link 8 27,084,789 27,112,986 RGD:9068941
G RPL11 ribosomal protein L11 JBrowse link 1 22,883,157 22,887,806 RGD:9068941
G RYBP RING1 and YY1 binding protein JBrowse link 3 72,315,494 72,389,328 RGD:9068941
G SDCBP syndecan binding protein JBrowse link 8 54,992,627 55,022,560 RGD:9068941
G SENP1 SUMO specific peptidase 1 JBrowse link 12 40,624,200 40,689,837 RGD:9068941
G SHH sonic hedgehog signaling molecule JBrowse link 7 147,400,112 147,414,036 RGD:9068941
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 JBrowse link 3 47,487,948 47,683,623 RGD:9068941
G TAF9 TATA-box binding protein associated factor 9 JBrowse link 5 44,630,503 44,635,760 RGD:9068941
G TLK2 tousled like kinase 2 JBrowse link 17 56,542,670 56,678,294 RGD:9068941
G TRIM39 tripartite motif containing 39 JBrowse link 6 30,104,381 30,121,649 RGD:9068941
G UBXN1 UBX domain protein 1 JBrowse link 11 58,033,304 58,035,893 RGD:9068941
G UCHL5 ubiquitin C-terminal hydrolase L5 JBrowse link 1 168,471,501 168,519,366 RGD:9068941
G USP7 ubiquitin specific peptidase 7 JBrowse link 16 7,825,332 7,895,095 RGD:9068941
G WAC WW domain containing adaptor with coiled-coil JBrowse link 10 28,685,294 28,777,176 RGD:9068941
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G STYX serine/threonine/tyrosine interacting protein JBrowse link 14 33,326,587 33,371,399 RGD:9068941
negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A JBrowse link 6 34,450,695 34,653,881 RGD:9068941
G CDKN2A cyclin dependent kinase inhibitor 2A JBrowse link 9 21,803,862 21,831,322 RGD:9068941
G CSNK2A1 casein kinase 2 alpha 1 JBrowse link 20 689,494 752,092 RGD:9068941
G CSNK2A2 casein kinase 2 alpha 2 JBrowse link 16 38,426,399 38,466,575 RGD:9068941
G HFE homeostatic iron regulator JBrowse link 6 25,921,663 25,930,852 RGD:9068941
G HIPK2 homeodomain interacting protein kinase 2 JBrowse link 7 131,506,711 131,722,943 RGD:9068941
G PDCL3 phosducin like 3 RGD:9068941
G PML PML nuclear body scaffold JBrowse link 15 52,903,874 52,955,151 RGD:9068941
G PSEN1 presenilin 1 JBrowse link 14 53,718,299 53,802,684 RGD:9068941
G PSEN2 presenilin 2 JBrowse link 1 202,328,987 202,354,440 RGD:9068941
G QRICH2 glutamine rich 2 JBrowse link 17 70,222,033 70,256,747 RGD:9068941
G RPL11 ribosomal protein L11 JBrowse link 1 22,883,157 22,887,806 RGD:9068941
G RPL23 ribosomal protein L23 JBrowse link 17 18,417,964 18,421,708 RGD:9068941
G RPL5 ribosomal protein L5 JBrowse link 1 95,497,047 95,507,006 RGD:9068941
G RPS7 ribosomal protein S7 JBrowse link 2A 3,593,350 3,599,106 RGD:9068941
G SGTA small glutamine rich tetratricopeptide repeat containing alpha JBrowse link 19 1,778,728 1,808,199 RGD:9068941
G SUFU SUFU negative regulator of hedgehog signaling JBrowse link 10 99,107,516 99,231,761 RGD:9068941
G TAF1 TATA-box binding protein associated factor 1 JBrowse link X 60,630,137 60,729,904 RGD:9068941
G TRIM39 tripartite motif containing 39 JBrowse link 6 30,104,381 30,121,649 RGD:9068941
G WNT1 Wnt family member 1 JBrowse link 12 39,767,839 39,772,460 RGD:9068941
nuclear protein quality control by the ubiquitin-proteasome system term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CUL3 cullin 3 JBrowse link 2B 111,714,533 111,827,080 RGD:9068941
G KLHL15 kelch like family member 15 JBrowse link X 16,583,117 16,625,029 RGD:9068941
positive regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCAP31 B cell receptor associated protein 31 JBrowse link X 143,265,920 143,274,956 RGD:9068941
G CAV1 caveolin 1 JBrowse link 7 108,497,125 108,533,090 RGD:9068941
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 16 37,210,170 37,221,961 RGD:9068941
G SGTA small glutamine rich tetratricopeptide repeat containing alpha JBrowse link 19 1,778,728 1,808,199 RGD:9068941
G UBQLN1 ubiquilin 1 JBrowse link 9 41,170,416 41,218,656 RGD:9068941
G UBQLN2 ubiquilin 2 JBrowse link X 48,829,844 48,835,040 RGD:9068941
positive regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 85,417,229 85,444,722 RGD:9068941
G ATG7 autophagy related 7 JBrowse link 3 11,208,600 11,488,757 RGD:9068941
G AURKA aurora kinase A JBrowse link 20 52,707,757 52,730,579 RGD:9068941
G AXIN1 axin 1 RGD:9068941
G BAG2 BAG cochaperone 2 JBrowse link 6 56,730,297 56,743,123 RGD:9068941
G BBS7 Bardet-Biedl syndrome 7 JBrowse link 4 114,024,949 114,072,000 RGD:9068941
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 JBrowse link 16 69,592,293 69,662,321 RGD:9068941
G CLU clusterin JBrowse link 8 26,867,973 26,884,838 RGD:9068941
G COP1 COP1 E3 ubiquitin ligase JBrowse link 1 151,459,354 151,727,131 RGD:9068941
G CSNK1A1 casein kinase 1 alpha 1 JBrowse link 5 144,919,775 144,977,105 RGD:9068941
G CSNK1D casein kinase 1 delta JBrowse link 17 76,648,677 76,683,054 RGD:9068941
G CSNK1E casein kinase 1 epsilon JBrowse link 22 19,202,599 19,229,344 RGD:9068941
G DDRGK1 DDRGK domain containing 1 JBrowse link 20 3,276,292 3,290,433 RGD:9068941
G DET1 DET1 partner of COP1 E3 ubiquitin ligase JBrowse link 15 67,203,101 67,238,185 RGD:9068941
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 JBrowse link 2B 106,536,846 106,544,430 RGD:9068941
G DVL1 dishevelled segment polarity protein 1 JBrowse link 1 92,469 106,748 RGD:9068941
G FAM122A family with sequence similarity 122A JBrowse link 9 56,007,323 56,011,655 RGD:9068941
G FBXO22 F-box protein 22 JBrowse link 15 54,817,076 54,849,271 RGD:9068941
G GCLC glutamate-cysteine ligase catalytic subunit JBrowse link 6 53,052,145 53,102,794 RGD:9068941
G GSK3A glycogen synthase kinase 3 alpha JBrowse link 19 39,118,330 39,130,768 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 116,943,205 117,215,001 RGD:9068941
G HSPA1A heat shock protein family A (Hsp70) member 1A JBrowse link 6 31,476,710 31,491,411 RGD:9068941
G HSPBP1 HSPA (Hsp70) binding protein 1 JBrowse link 19 52,303,121 52,322,771 RGD:9068941
G IL33 interleukin 33 JBrowse link 9 6,027,014 6,069,540 RGD:9068941
G KLHL40 kelch like family member 40 JBrowse link 3 42,592,977 42,600,100 RGD:9068941
G LOC100974874 E3 ubiquitin-protein ligase CHFR JBrowse link 12 130,201,704 130,247,891 RGD:9068941
G LRRK2 leucine rich repeat kinase 2 JBrowse link 12 48,343,621 48,488,337 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 12 66,322,340 66,357,010 RGD:9068941
G NKD2 NKD inhibitor of WNT signaling pathway 2 JBrowse link 5 1,285,217 1,311,285 RGD:9068941
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 19 44,739,739 44,751,303 RGD:9068941
G NUB1 negative regulator of ubiquitin like proteins 1 JBrowse link 7 142,927,730 142,964,475 RGD:9068941
G PIAS1 protein inhibitor of activated STAT 1 JBrowse link 15 47,006,718 47,141,035 RGD:9068941
G PLK1 polo like kinase 1 JBrowse link 16 14,420,972 14,432,821 RGD:9068941
G PLK2 polo like kinase 2 JBrowse link 5 55,543,828 55,550,116 RGD:9068941
G PRICKLE1 prickle planar cell polarity protein 1 JBrowse link 12 46,127,673 46,262,333 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 6 159,293,016 160,679,106 RGD:9068941
G PSEN1 presenilin 1 JBrowse link 14 53,718,299 53,802,684 RGD:9068941
G PSEN2 presenilin 2 JBrowse link 1 202,328,987 202,354,440 RGD:9068941
G PSMD10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 97,182,090 97,189,523 RGD:9068941
G RACK1 receptor for activated C kinase 1 JBrowse link 5 176,462,991 176,470,153 RGD:9068941
G RAD23A RAD23 homolog A, nucleotide excision repair protein JBrowse link 19 12,508,232 12,516,068 RGD:9068941
G RBX1 ring-box 1 JBrowse link 22 21,845,351 21,866,627 RGD:9068941
G RCHY1 ring finger and CHY zinc finger domain containing 1 JBrowse link 4 48,691,213 48,725,979 RGD:9068941
G RFPL1 ret finger protein like 1 JBrowse link 22 10,485,218 10,488,052 RGD:9068941
G RNF180 ring finger protein 180 JBrowse link 5 49,624,452 49,841,741 RGD:9068941
G SH3RF2 SH3 domain containing ring finger 2 JBrowse link 5 141,386,060 141,530,993 RGD:9068941
G SIRT2 sirtuin 2 JBrowse link 19 35,984,453 36,005,582 RGD:9068941
G SMAD7 SMAD family member 7 JBrowse link 18 42,306,324 42,337,214 RGD:9068941
G SOCS5 suppressor of cytokine signaling 5 JBrowse link 2A 46,813,589 46,878,102 RGD:9068941
G STUB1 STIP1 homology and U-box containing protein 1 RGD:9068941
G SUMO1 small ubiquitin like modifier 1 JBrowse link 2B 89,461,773 89,493,879 RGD:9068941
G SUMO2 small ubiquitin like modifier 2 JBrowse link 17 69,115,433 69,130,065 RGD:9068941
G TAF1 TATA-box binding protein associated factor 1 JBrowse link X 60,630,137 60,729,904 RGD:9068941
G TRIB1 tribbles pseudokinase 1 JBrowse link 8 122,115,194 122,123,319 RGD:9068941
G TRIB2 tribbles pseudokinase 2 JBrowse link 2A 12,705,043 12,730,932 RGD:9068941
G UBE2V2 ubiquitin conjugating enzyme E2 V2 JBrowse link 8 44,435,496 44,488,517 RGD:9068941
G USP5 ubiquitin specific peptidase 5 JBrowse link 12 6,983,941 6,998,469 RGD:9068941
G VCP valosin containing protein JBrowse link 9 34,907,147 34,923,227 RGD:9068941
G ZER1 zyg-11 related cell cycle regulator JBrowse link 9 99,853,433 99,895,399 RGD:9068941
G ZFAND2A zinc finger AN1-type containing 2A JBrowse link 7 1,392,979 1,401,283 RGD:9068941
G ZYG11B zyg-11 family member B, cell cycle regulator JBrowse link 1 51,987,678 52,087,093 RGD:9068941
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PLK3 polo like kinase 3 JBrowse link 1 44,104,564 44,110,162 RGD:9068941
G SIRT2 sirtuin 2 JBrowse link 19 35,984,453 36,005,582 RGD:9068941
positive regulation of transcription factor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FBXW8 F-box and WD repeat domain containing 8 JBrowse link 12 114,487,476 114,607,384 RGD:9068941
G MAPK8 mitogen-activated protein kinase 8 JBrowse link 10 45,806,748 45,936,362 RGD:9068941
G MAPK9 mitogen-activated protein kinase 9 JBrowse link 5 175,437,167 175,495,469 RGD:9068941
G SIRT6 sirtuin 6 JBrowse link 19 3,196,092 3,204,602 RGD:9068941
positive regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGBL4 ATP/GTP binding protein like 4 JBrowse link 1 47,807,888 49,264,213 RGD:9068941
G AXIN1 axin 1 RGD:9068941
G CCDC22 coiled-coil domain containing 22 JBrowse link X 41,535,439 41,550,547 RGD:9068941
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 JBrowse link 17 9,556,313 9,567,099 RGD:9068941
G CLU clusterin JBrowse link 8 26,867,973 26,884,838 RGD:9068941
G DISC1 DISC1 scaffold protein JBrowse link 1 207,180,513 207,594,684 RGD:9068941
G EGF epidermal growth factor JBrowse link 4 102,410,724 102,509,691 RGD:9068941
G FBXO22 F-box protein 22 JBrowse link 15 54,817,076 54,849,271 RGD:9068941
G FBXW7 F-box and WD repeat domain containing 7 JBrowse link 4 144,660,676 144,874,404 RGD:9068941
G LOC100970998 small ubiquitin like modifier 3 JBrowse link 1 224,215,377 224,217,052 RGD:9068941
G MAGEF1 MAGE family member F1 JBrowse link 3 181,750,186 181,751,900 RGD:9068941
G PTEN phosphatase and tensin homolog JBrowse link 10 84,587,841 84,689,043 RGD:9068941
G PTK2 protein tyrosine kinase 2 JBrowse link 8 137,330,777 137,677,306 RGD:9068941
G PTK2B protein tyrosine kinase 2 beta JBrowse link 8 26,580,855 26,729,378 RGD:9068941
G PYHIN1 pyrin and HIN domain family member 1 JBrowse link 1 134,283,998 134,329,531 RGD:9068941
G RNF139 ring finger protein 139 JBrowse link 8 121,158,715 121,172,069 RGD:9068941
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 JBrowse link 7 90,995,923 91,112,240 RGD:9068941
G TRIM67 tripartite motif containing 67 JBrowse link 1 206,710,490 206,770,111 RGD:9068941
proteasome-mediated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 JBrowse link 7 142,672,773 142,731,261 RGD:9068941
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 11 13,436,580 13,547,135 RGD:9068941
G ARRB1 arrestin beta 1 JBrowse link 11 70,319,935 70,411,276 RGD:9068941
G ARRB2 arrestin beta 2 JBrowse link 17 4,766,616 4,777,253 RGD:9068941
G ATXN3 ataxin 3 JBrowse link 14 72,693,446 72,741,772 RGD:9068941
G BAG6 BAG cochaperone 6 JBrowse link 6 31,300,126 31,313,829 RGD:9068941
G BFAR bifunctional apoptosis regulator JBrowse link 16 13,558,912 13,597,023 RGD:9068941
G BIRC2 baculoviral IAP repeat containing 2 JBrowse link 11 97,298,736 97,324,966 RGD:9068941
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase JBrowse link 10 97,958,527 98,159,550 RGD:9068941
G CD2AP CD2 associated protein JBrowse link 6 47,065,284 47,210,746 RGD:9068941
G CDC34 cell division cycle 34, ubiqiutin conjugating enzyme JBrowse link 19 592,856 602,811 RGD:9068941
G CLOCK clock circadian regulator JBrowse link 4 68,391,310 68,509,813 RGD:9068941
G COP1 COP1 E3 ubiquitin ligase JBrowse link 1 151,459,354 151,727,131 RGD:9068941
G CRBN cereblon JBrowse link 3 3,091,328 3,121,364 RGD:9068941
G CTNNB1 catenin beta 1 JBrowse link 3 41,104,940 41,145,934 RGD:9068941
G CUL3 cullin 3 JBrowse link 2B 111,714,533 111,827,080 RGD:9068941
G CUL4A cullin 4A JBrowse link 13 94,350,484 94,409,183 RGD:9068941
G DDB1 damage specific DNA binding protein 1 JBrowse link 11 56,599,422 56,633,140 RGD:9068941
G DDIT3 DNA damage inducible transcript 3 JBrowse link 12 31,406,332 31,410,293 RGD:9068941
G DERL1 derlin 1 JBrowse link 8 119,707,397 119,736,502 RGD:9068941
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 JBrowse link 2B 106,536,846 106,544,430 RGD:9068941
G EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 JBrowse link 1 160,217,526 160,281,785 RGD:9068941
G EPM2A EPM2A glucan phosphatase, laforin JBrowse link 6 143,179,097 143,525,223 RGD:9068941
G ERCC8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit JBrowse link 5 53,053,712 53,131,563 RGD:9068941
G FAF2 Fas associated factor family member 2 JBrowse link 5 171,743,071 171,804,687 RGD:9068941
G FBXL17 F-box and leucine rich repeat protein 17 JBrowse link 5 103,214,110 103,739,494 RGD:9068941
G FBXL19 F-box and leucine rich repeat protein 19 JBrowse link 16 24,020,365 24,046,217 RGD:9068941
G FBXL22 F-box and leucine rich repeat protein 22 JBrowse link 15 42,543,909 42,548,938 RGD:9068941
G FBXL3 F-box and leucine rich repeat protein 3 JBrowse link 13 58,219,260 58,244,780 RGD:9068941
G FBXO45 F-box protein 45 JBrowse link 3 193,913,712 193,934,123 RGD:9068941
G FBXW11 F-box and WD repeat domain containing 11 JBrowse link 5 167,207,643 167,354,730 RGD:9068941
G FBXW5 F-box and WD repeat domain containing 5 JBrowse link 9 107,998,949 108,003,247 RGD:9068941
G FBXW7 F-box and WD repeat domain containing 7 JBrowse link 4 144,660,676 144,874,404 RGD:9068941
G GSK3A glycogen synthase kinase 3 alpha JBrowse link 19 39,118,330 39,130,768 RGD:9068941
G HECTD3 HECT domain E3 ubiquitin protein ligase 3 JBrowse link 1 44,306,327 44,315,131 RGD:9068941
G IFI27 interferon alpha inducible protein 27 JBrowse link 14 74,742,775 74,748,820 RGD:9068941
G KAT5 lysine acetyltransferase 5 JBrowse link 11 61,071,118 61,078,667 RGD:9068941
G KCTD13 potassium channel tetramerization domain containing 13 RGD:9068941
G KCTD17 potassium channel tetramerization domain containing 17 JBrowse link 22 17,965,397 17,977,048 RGD:9068941
G KIF14 kinesin family member 14 JBrowse link 1 176,156,870 176,223,093 RGD:9068941
G KLHL20 kelch like family member 20 JBrowse link 1 149,232,858 149,303,357 RGD:9068941
G KLHL22 kelch like family member 22 RGD:9068941
G KLHL42 kelch like family member 42 JBrowse link 12 58,509,031 58,531,891 RGD:9068941
G LOC100976978 E3 ubiquitin-protein ligase HERC2 JBrowse link 15 1,590,558 1,800,023 RGD:9068941
G MARCHF6 membrane associated ring-CH-type finger 6 JBrowse link 5 10,666,978 10,753,050 RGD:9068941
G MTA1 metastasis associated 1 JBrowse link 14 86,058,412 86,111,736 RGD:9068941
G NEDD4L NEDD4 like E3 ubiquitin protein ligase JBrowse link 18 51,428,077 51,792,995 RGD:9068941
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2B 64,509,446 64,544,600 RGD:9068941
G NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 JBrowse link 6 17,969,146 17,970,962 RGD:9068941
G OTUD5 OTU deubiquitinase 5 JBrowse link X 41,219,536 41,256,219 RGD:9068941
G PCBP2 poly(rC) binding protein 2 JBrowse link 12 35,273,540 35,301,292 RGD:9068941
G PCNP PEST proteolytic signal containing nuclear protein JBrowse link 3 98,683,411 98,703,664 RGD:9068941
G PELI1 pellino E3 ubiquitin protein ligase 1 JBrowse link 2A 64,160,362 64,213,200 RGD:9068941
G PML PML nuclear body scaffold JBrowse link 15 52,903,874 52,955,151 RGD:9068941
G PMP22 peripheral myelin protein 22 JBrowse link 17 36,389,549 36,425,161 RGD:9068941
G PPP2CB protein phosphatase 2 catalytic subunit beta JBrowse link 8 30,099,605 30,126,917 RGD:9068941
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma JBrowse link 14 82,383,086 82,549,822 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 6 159,293,016 160,679,106 RGD:9068941
G PSMB5 proteasome 20S subunit beta 5 JBrowse link 14 3,845,951 3,855,335 RGD:9068941
G PSMC5 proteasome 26S subunit, ATPase 5 JBrowse link 17 57,906,934 57,911,551 RGD:9068941
G RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1 JBrowse link 20 615,987 639,366 RGD:9068941
G RBX1 ring-box 1 JBrowse link 22 21,845,351 21,866,627 RGD:9068941
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase JBrowse link 17 21,696,808 21,779,878 RGD:9068941
G RNF122 ring finger protein 122 JBrowse link 8 32,862,364 32,881,660 RGD:9068941
G RNF186 ring finger protein 186 JBrowse link 1 18,770,083 18,772,399 RGD:9068941
G RNF187 ring finger protein 187 JBrowse link 1 203,889,146 203,896,884 RGD:9068941
G RNF216 ring finger protein 216 JBrowse link 7 5,872,118 6,037,073 RGD:9068941
G RNF34 ring finger protein 34 JBrowse link 12 118,998,436 119,022,823 RGD:9068941
G RNF4 ring finger protein 4 JBrowse link 4 2,614,918 2,661,785 RGD:9068941
G SIAH1 siah E3 ubiquitin protein ligase 1 JBrowse link 16 28,627,021 28,651,343 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 10 64,368,878 64,401,684 RGD:9068941
G SIRT2 sirtuin 2 JBrowse link 19 35,984,453 36,005,582 RGD:9068941
G SKP2 S-phase kinase associated protein 2 JBrowse link 5 74,179,608 74,211,563 RGD:9068941
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 JBrowse link 7 90,995,923 91,112,240 RGD:9068941
G SPOP speckle type BTB/POZ protein JBrowse link 17 43,685,913 43,765,277 RGD:9068941
G SPOPL speckle type BTB/POZ protein like JBrowse link 2B 21,280,143 21,351,547 RGD:9068941
G STUB1 STIP1 homology and U-box containing protein 1 RGD:9068941
G TBL1X transducin beta like 1 X-linked JBrowse link X 2,096,684 2,352,951 RGD:9068941
G TBL1XR1 TBL1X receptor 1 JBrowse link 3 174,067,964 174,251,913 RGD:9068941
G TBX21 T-box transcription factor 21 JBrowse link 17 9,791,008 9,803,894 RGD:9068941
G TNFAIP1 TNF alpha induced protein 1 JBrowse link 17 28,427,448 28,438,826 RGD:9068941
G TOPORS TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase JBrowse link 9 32,314,850 32,327,067 RGD:9068941
G TRIM13 tripartite motif containing 13 JBrowse link 13 31,137,236 31,153,398 RGD:9068941
G TRIM38 tripartite motif containing 38 JBrowse link 6 25,796,278 25,818,610 RGD:9068941
G TRIM63 tripartite motif containing 63 JBrowse link 1 25,309,949 25,373,658 RGD:9068941
G TRIM72 tripartite motif containing 72 JBrowse link 16 23,734,844 23,753,388 RGD:9068941
G TRIM9 tripartite motif containing 9 JBrowse link 14 31,577,859 31,844,298 RGD:9068941
G UBE2B ubiquitin conjugating enzyme E2 B JBrowse link 5 129,775,011 129,794,853 RGD:9068941
G UBE2D3 ubiquitin conjugating enzyme E2 D3 JBrowse link 4 95,218,319 95,293,053 RGD:9068941
G UBE2H ubiquitin conjugating enzyme E2 H JBrowse link 7 121,796,629 121,917,981 RGD:9068941
G UBE2I ubiquitin conjugating enzyme E2 I RGD:9068941
G UBE2W ubiquitin conjugating enzyme E2 W JBrowse link 8 70,315,767 70,413,148 RGD:9068941
G UBE4B ubiquitination factor E4B JBrowse link 1 8,801,707 8,949,465 RGD:9068941
G USP44 ubiquitin specific peptidase 44 JBrowse link 12 93,111,293 93,146,889 RGD:9068941
G VCP valosin containing protein JBrowse link 9 34,907,147 34,923,227 RGD:9068941
G WWP1 WW domain containing E3 ubiquitin protein ligase 1 JBrowse link 8 83,039,632 83,165,010 RGD:9068941
G WWP2 WW domain containing E3 ubiquitin protein ligase 2 JBrowse link 16 50,142,402 50,322,052 RGD:9068941
G ZFAND2B zinc finger AN1-type containing 2B JBrowse link 2B 106,464,364 106,467,217 RGD:9068941
G ZNRF1 zinc and ring finger 1 JBrowse link 16 55,567,875 55,679,524 RGD:9068941
protein arginylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATE1 arginyltransferase 1 JBrowse link 10 118,316,655 118,504,409 RGD:9068941
protein deubiquitination involved in ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G USP9X ubiquitin specific peptidase 9 X-linked JBrowse link X 33,535,543 33,683,220 RGD:9068941
G ZRANB1 zinc finger RANBP2-type containing 1 JBrowse link 10 121,477,916 121,549,296 RGD:9068941
regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 16 37,210,170 37,221,961 RGD:9068941
regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARAF A-Raf proto-oncogene, serine/threonine kinase JBrowse link X 39,997,026 40,007,783 RGD:9068941
G COMMD1 copper metabolism domain containing 1 JBrowse link 2A 61,970,830 62,216,677 RGD:9068941
G DESI1 desumoylating isopeptidase 1 JBrowse link 22 22,493,114 22,516,191 RGD:9068941
G FOXF2 forkhead box F2 JBrowse link 6 1,209,899 1,215,970 RGD:9068941
G GLMN glomulin, FKBP associated protein JBrowse link 1 94,907,342 94,963,052 RGD:9068941
G GNA12 G protein subunit alpha 12 JBrowse link 7 2,989,832 3,104,848 RGD:9068941
G RAD23A RAD23 homolog A, nucleotide excision repair protein JBrowse link 19 12,508,232 12,516,068 RGD:9068941
G RAD23B RAD23 homolog B, nucleotide excision repair protein JBrowse link 9 78,433,461 78,482,157 RGD:9068941
G UBE2K ubiquitin conjugating enzyme E2 K JBrowse link 4 34,026,942 34,111,923 RGD:9068941
G UBQLN4 ubiquilin 4 JBrowse link 1 131,374,635 131,395,986 RGD:9068941
G UFL1 UFM1 specific ligase 1 JBrowse link 6 94,356,440 94,389,920 RGD:9068941
G WNT10B Wnt family member 10B JBrowse link 12 39,771,163 39,785,411 RGD:9068941
G XPO1 exportin 1 JBrowse link 2A 61,562,372 61,622,841 RGD:9068941
regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LATS1 large tumor suppressor kinase 1 JBrowse link 6 147,476,913 147,533,491 RGD:9068941
G PTK2B protein tyrosine kinase 2 beta JBrowse link 8 26,580,855 26,729,378 RGD:9068941
G UBE3A ubiquitin protein ligase E3A JBrowse link 15 4,494,029 4,595,415 RGD:9068941
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase JBrowse link 10 97,958,527 98,159,550 RGD:9068941
G CCNF cyclin F JBrowse link 16 1,285,379 1,314,972 RGD:9068941
G CUL1 cullin 1 JBrowse link 7 140,428,442 140,531,136 RGD:9068941
G FBXL15 F-box and leucine rich repeat protein 15 JBrowse link 10 99,022,732 99,026,623 RGD:9068941
G FBXL17 F-box and leucine rich repeat protein 17 JBrowse link 5 103,214,110 103,739,494 RGD:9068941
G FBXL2 F-box and leucine rich repeat protein 2 JBrowse link 3 33,199,436 33,308,831 RGD:9068941
G FBXL3 F-box and leucine rich repeat protein 3 JBrowse link 13 58,219,260 58,244,780 RGD:9068941
G FBXL5 F-box and leucine rich repeat protein 5 JBrowse link 4 10,050,909 10,107,573 RGD:9068941
G FBXL7 F-box and leucine rich repeat protein 7 JBrowse link 5 15,804,479 16,237,326 RGD:9068941
G FBXO2 F-box protein 2 JBrowse link 1 10,408,853 10,415,174 RGD:9068941
G FBXO31 F-box protein 31 JBrowse link 16 67,997,481 68,053,081 RGD:9068941
G FBXO38 F-box protein 38 JBrowse link 5 143,814,446 143,873,919 RGD:9068941
G FBXO4 F-box protein 4 JBrowse link 5 68,336,673 68,474,481 RGD:9068941
G FBXO9 F-box protein 9 JBrowse link 6 52,621,036 52,652,980 RGD:9068941
G FBXW11 F-box and WD repeat domain containing 11 JBrowse link 5 167,207,643 167,354,730 RGD:9068941
G FBXW5 F-box and WD repeat domain containing 5 JBrowse link 9 107,998,949 108,003,247 RGD:9068941
G FBXW7 F-box and WD repeat domain containing 7 JBrowse link 4 144,660,676 144,874,404 RGD:9068941
G KIF14 kinesin family member 14 JBrowse link 1 176,156,870 176,223,093 RGD:9068941
G RBX1 ring-box 1 JBrowse link 22 21,845,351 21,866,627 RGD:9068941
G SKP1 S-phase kinase associated protein 1 JBrowse link 5 129,560,086 129,580,188 RGD:9068941
G WWTR1 WW domain containing transcription regulator 1 JBrowse link 3 146,536,564 146,678,847 RGD:9068941
transcription factor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TAF1 TATA-box binding protein associated factor 1 JBrowse link X 60,630,137 60,729,904 RGD:9068941
ubiquitin-dependent ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AMFR autocrine motility factor receptor JBrowse link 16 36,647,792 36,711,782 RGD:9068941
G AUP1 AUP1 lipid droplet regulating VLDL assembly factor JBrowse link 2A 74,593,260 74,596,372 RGD:9068941
G BAG6 BAG cochaperone 6 JBrowse link 6 31,300,126 31,313,829 RGD:9068941
G CCDC47 coiled-coil domain containing 47 JBrowse link 17 57,825,328 57,853,626 RGD:9068941
G DERL1 derlin 1 JBrowse link 8 119,707,397 119,736,502 RGD:9068941
G DERL2 derlin 2 JBrowse link 17 5,519,183 5,534,145 RGD:9068941
G DERL3 derlin 3 JBrowse link 22 4,589,448 4,594,628 RGD:9068941
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 JBrowse link 2B 106,536,846 106,544,430 RGD:9068941
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 JBrowse link 7 100,555,527 100,560,052 RGD:9068941
G DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 JBrowse link 2B 69,991,321 70,059,693 RGD:9068941
G ECPAS Ecm29 proteasome adaptor and scaffold JBrowse link 9 82,499,075 82,623,007 RGD:9068941
G EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 3 5,133,927 5,162,485 RGD:9068941
G ERLEC1 endoplasmic reticulum lectin 1 JBrowse link 2A 53,930,280 53,962,178 RGD:9068941
G ERLIN1 ER lipid raft associated 1 JBrowse link 10 96,756,261 96,791,925 RGD:9068941
G ERLIN2 ER lipid raft associated 2 JBrowse link 8 37,034,391 37,057,164 RGD:9068941
G FAF2 Fas associated factor family member 2 JBrowse link 5 171,743,071 171,804,687 RGD:9068941
G FBXO2 F-box protein 2 JBrowse link 1 10,408,853 10,415,174 RGD:9068941
G FOXRED2 FAD dependent oxidoreductase domain containing 2 JBrowse link 22 17,402,084 17,421,990 RGD:9068941
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 16 37,210,170 37,221,961 RGD:9068941
G HSP90B1 heat shock protein 90 beta family member 1 JBrowse link 12 101,506,845 101,524,407 RGD:9068941
G JKAMP JNK1/MAPK8 associated membrane protein JBrowse link 14 40,087,037 40,107,897 RGD:9068941
G MAN1B1 mannosidase alpha class 1B member 1 JBrowse link 9 108,148,020 108,168,931 RGD:9068941
G OS9 OS9 endoplasmic reticulum lectin JBrowse link 12 31,205,239 31,232,769 RGD:9068941
G RNF103 ring finger protein 103 JBrowse link 2A 86,659,672 86,680,154 RGD:9068941
G RNF185 ring finger protein 185 JBrowse link 22 12,183,591 12,230,371 RGD:9068941
G RNF5 ring finger protein 5 JBrowse link 6 31,825,799 31,828,188 RGD:9068941
G SEC61B SEC61 translocon subunit beta JBrowse link 9 70,312,061 70,320,448 RGD:9068941
G SELENOS selenoprotein S JBrowse link 15 79,995,678 80,002,159 RGD:9068941
G SGTA small glutamine rich tetratricopeptide repeat containing alpha JBrowse link 19 1,778,728 1,808,199 RGD:9068941
G STT3B STT3 oligosaccharyltransferase complex catalytic subunit B JBrowse link 3 31,454,297 31,557,189 RGD:9068941
G STUB1 STIP1 homology and U-box containing protein 1 RGD:9068941
G SYVN1 synoviolin 1 JBrowse link 11 60,489,626 60,496,945 RGD:9068941
G TMEM129 transmembrane protein 129, E3 ubiquitin ligase JBrowse link 4 1,853,126 1,858,461 RGD:9068941
G TMEM67 transmembrane protein 67 JBrowse link 8 90,378,623 90,442,904 RGD:9068941
G TMUB1 transmembrane and ubiquitin like domain containing 1 JBrowse link 7 142,667,937 142,670,443 RGD:9068941
G TRIM13 tripartite motif containing 13 JBrowse link 13 31,137,236 31,153,398 RGD:9068941
G TRIM25 tripartite motif containing 25 JBrowse link 17 50,965,592 50,991,630 RGD:9068941
G UBE2G2 ubiquitin conjugating enzyme E2 G2 JBrowse link 21 31,062,516 31,095,044 RGD:9068941
G UBE2J1 ubiquitin conjugating enzyme E2 J1 JBrowse link 6 87,196,938 87,223,414 RGD:9068941
G UBE2J2 ubiquitin conjugating enzyme E2 J2 JBrowse link 1 8,756 28,672 RGD:9068941
G UBQLN1 ubiquilin 1 JBrowse link 9 41,170,416 41,218,656 RGD:9068941
G UBQLN2 ubiquilin 2 JBrowse link X 48,829,844 48,835,040 RGD:9068941
G UBXN4 UBX domain protein 4 JBrowse link 2B 24,081,450 24,124,876 RGD:9068941
G UBXN8 UBX domain protein 8 JBrowse link 8 30,057,469 30,080,778 RGD:9068941
G UMOD uromodulin JBrowse link 16 17,960,456 17,980,338 RGD:9068941
G USP19 ubiquitin specific peptidase 19 JBrowse link 3 49,032,373 49,045,238 RGD:9068941
G VCP valosin containing protein JBrowse link 9 34,907,147 34,923,227 RGD:9068941
G WFS1 wolframin ER transmembrane glycoprotein RGD:9068941
G YOD1 YOD1 deubiquitinase JBrowse link 1 182,646,727 182,655,141 RGD:9068941
ubiquitin-dependent glycoprotein ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 3 5,133,927 5,162,485 RGD:9068941
G EDEM2 ER degradation enhancing alpha-mannosidase like protein 2 JBrowse link 20 31,443,590 31,475,430 RGD:9068941
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HDAC6 histone deacetylase 6 JBrowse link X 41,099,539 41,122,650 RGD:9068941
G NEDD4 NEDD4 E3 ubiquitin protein ligase JBrowse link 15 34,798,880 34,963,823 RGD:9068941
G PLAA phospholipase A2 activating protein JBrowse link 9 26,749,607 26,793,580 RGD:9068941
G PTPN23 protein tyrosine phosphatase non-receptor type 23 JBrowse link 3 47,280,706 47,314,268 RGD:9068941
G RNF115 ring finger protein 115 JBrowse link 1 121,936,054 122,016,273 RGD:9068941
G TSG101 tumor susceptibility 101 JBrowse link 11 18,518,110 18,564,814 RGD:9068941
G UBAP1 ubiquitin associated protein 1 JBrowse link 9 34,015,077 34,088,908 RGD:9068941
G VPS28 VPS28 subunit of ESCRT-I JBrowse link 8 141,189,967 141,195,482 RGD:9068941
G VPS37A VPS37A subunit of ESCRT-I JBrowse link 8 16,459,660 16,508,333 RGD:9068941
G VPS4A vacuolar protein sorting 4 homolog A JBrowse link 16 49,685,827 49,699,542 RGD:9068941
G VPS4B vacuolar protein sorting 4 homolog B JBrowse link 18 56,749,439 56,782,660 RGD:9068941
ubiquitin-dependent SMAD protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RNF111 ring finger protein 111 JBrowse link 15 37,957,390 38,068,006 RGD:9068941
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 JBrowse link 7 90,995,923 91,112,240 RGD:9068941
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 JBrowse link 17 58,638,995 58,759,443 RGD:9068941
G STUB1 STIP1 homology and U-box containing protein 1 RGD:9068941
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 JBrowse link 16 23,487,561 23,493,452 RGD:9068941
G WNT1 Wnt family member 1 JBrowse link 12 39,767,839 39,772,460 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12489
    metabolic process 7937
      catabolic process 1686
        cellular catabolic process 1466
          cellular macromolecule catabolic process 757
            modification-dependent macromolecule catabolic process 394
              modification-dependent protein catabolic process 388
                ubiquitin-dependent protein catabolic process 383
                  negative regulation of ubiquitin-dependent protein catabolic process + 52
                  positive regulation of ubiquitin-dependent protein catabolic process + 87
                  proteasome-mediated ubiquitin-dependent protein catabolic process + 262
                  protein arginylation 1
                  protein deubiquitination involved in ubiquitin-dependent protein catabolic process 2
                  regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism 0
                  regulation of ubiquitin-dependent protein catabolic process + 146
                  ubiquitin-dependent SMAD protein catabolic process 6
                  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway + 11
Path 2
Term Annotations click to browse term
  biological_process 12489
    metabolic process 7937
      catabolic process 1686
        organic substance catabolic process 1397
          macromolecule catabolic process 945
            cellular macromolecule catabolic process 757
              cellular protein catabolic process 530
                proteolysis involved in cellular protein catabolic process 477
                  modification-dependent protein catabolic process 388
                    ubiquitin-dependent protein catabolic process 383
                      negative regulation of ubiquitin-dependent protein catabolic process + 52
                      positive regulation of ubiquitin-dependent protein catabolic process + 87
                      proteasome-mediated ubiquitin-dependent protein catabolic process + 262
                      protein arginylation 1
                      protein deubiquitination involved in ubiquitin-dependent protein catabolic process 2
                      regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism 0
                      regulation of ubiquitin-dependent protein catabolic process + 146
                      ubiquitin-dependent SMAD protein catabolic process 6
                      ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.