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ONTOLOGY REPORT - ANNOTATIONS


Term:ubiquitin-dependent protein catabolic process
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Accession:GO:0006511 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
Synonyms:exact_synonym: ubiquitin-dependent protein breakdown;   ubiquitin-dependent protein catabolism;   ubiquitin-dependent protein degradation;   ubiquitin-dependent proteolysis
 narrow_synonym: myofibrillar protein ubiquitination during ubiquitin-dependent protein breakdown;   myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process;   myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolism;   myofibrillar protein ubiquitination during ubiquitin-dependent protein degradation;   protein ubiquitination during ubiquitin-dependent protein breakdown;   protein ubiquitination during ubiquitin-dependent protein catabolism;   protein ubiquitination during ubiquitin-dependent protein degradation;   protein ubiquitinylation during ubiquitin-dependent protein catabolic process;   protein ubiquitinylation during ubiquitin-dependent protein catabolism;   protein ubiquitylation during ubiquitin-dependent protein catabolic process;   protein ubiquitylation during ubiquitin-dependent protein catabolism
 broad_synonym: protein degradation tagging activity
 related_synonym: protein ubiquitination during ubiquitin-dependent protein catabolic process;   protein ubiquitination involved in ubiquitin-dependent protein catabolic process
 alt_id: GO:0042787;   GO:0043432


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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 130258
    metabolic process 79339
      catabolic process 17029
        cellular catabolic process 14751
          cellular macromolecule catabolic process 7723
            modification-dependent macromolecule catabolic process 4365
              modification-dependent protein catabolic process 4293
                ubiquitin-dependent protein catabolic process 4221
                  negative regulation of ubiquitin-dependent protein catabolic process + 405
                  positive regulation of ubiquitin-dependent protein catabolic process + 777
                  proteasome-mediated ubiquitin-dependent protein catabolic process + 2810
                  protein arginylation 15
                  protein deubiquitination involved in ubiquitin-dependent protein catabolic process 41
                  regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism 0
                  regulation of ubiquitin-dependent protein catabolic process + 1238
                  ubiquitin-dependent SMAD protein catabolic process 48
                  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway + 136
Path 2
Term Annotations click to browse term
  biological_process 130258
    metabolic process 79339
      catabolic process 17029
        organic substance catabolic process 14133
          macromolecule catabolic process 9343
            cellular macromolecule catabolic process 7723
              cellular protein catabolic process 5473
                proteolysis involved in cellular protein catabolic process 5050
                  modification-dependent protein catabolic process 4293
                    ubiquitin-dependent protein catabolic process 4221
                      negative regulation of ubiquitin-dependent protein catabolic process + 405
                      positive regulation of ubiquitin-dependent protein catabolic process + 777
                      proteasome-mediated ubiquitin-dependent protein catabolic process + 2810
                      protein arginylation 15
                      protein deubiquitination involved in ubiquitin-dependent protein catabolic process 41
                      regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism 0
                      regulation of ubiquitin-dependent protein catabolic process + 1238
                      ubiquitin-dependent SMAD protein catabolic process 48
                      ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway + 136
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.