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ONTOLOGY REPORT - ANNOTATIONS


Term:GPI anchor metabolic process
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Accession:GO:0006505 term browser browse the term
Definition:The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.
Synonyms:exact_synonym: GPI anchor metabolism;   glycosylphosphatidylinositol metabolic process;   glycosylphosphatidylinositol metabolism
 broad_synonym: GPI/GSI anchor metabolic process;   GPI/GSI anchor metabolism
 alt_id: GO:0046472



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GPI anchor metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgap1 post-GPI attachment to proteins 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 1:54,512,159...54,596,843
Ensembl chr 1:54,512,153...54,596,843
JBrowse link
G Pgap3 post-GPI attachment to proteins 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:98,279,498...98,292,022
Ensembl chr11:98,279,503...98,291,316
JBrowse link
G Pigb phosphatidylinositol glycan anchor biosynthesis, class B acts_upstream_of_or_within ISS (MGI:1890020|PMID:8861954) MGI PMID:8861954 MGI:1890020 NCBI chr 9:72,920,639...72,946,973
Ensembl chr 9:72,914,701...72,947,660
JBrowse link
attachment of GPI anchor to protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpaa1 GPI anchor attachment protein 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr15:76,215,494...76,219,099
Ensembl chr15:76,215,431...76,219,107
JBrowse link
G Pigk phosphatidylinositol glycan anchor biosynthesis, class K involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:152,419,718...152,548,705
Ensembl chr 3:152,419,737...152,686,045
JBrowse link
G Pigs phosphatidylinositol glycan anchor biosynthesis, class S involved_in IMP
IBA
(MGI:3688056|PMID:11483512)
(MGI:6201960|PMID:21873635)
UniProt
GO_Central
PMID:11483512 PMID:21873635 MGI:3688056 MGI:6201960 NCBI chr11:78,219,272...78,233,602
Ensembl chr11:78,219,241...78,233,608
JBrowse link
G Pigt phosphatidylinositol glycan anchor biosynthesis, class T involved_in IMP
IBA
(MGI:3688056|PMID:11483512)
(MGI:6201960|PMID:21873635)
UniProt
GO_Central
PMID:11483512 PMID:21873635 MGI:3688056 MGI:6201960 NCBI chr 2:164,339,461...164,350,221
Ensembl chr 2:164,339,440...164,350,221
JBrowse link
G Pigu phosphatidylinositol glycan anchor biosynthesis, class U involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000119 MGI:4834177 MGI:6201960 NCBI chr 2:155,120,163...155,199,344
Ensembl chr 2:155,120,163...155,199,350
JBrowse link
GPI anchor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cwh43 cell wall biogenesis 43 C-terminal homolog involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 5:73,563,394...73,610,778
Ensembl chr 5:73,563,418...73,610,778
JBrowse link
G Dpm1 dolichyl-phosphate mannosyltransferase subunit 1, catalytic acts_upstream_of_or_within
involved_in
ISO
IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:1329093|PMID:9535917)
MGI
GO_Central
PMID:9535917 PMID:21873635 GO_REF:0000008 MGI:1329093 MGI:2154458 MGI:6201960 NCBI chr 2:168,050,968...168,072,299
Ensembl chr 2:168,050,968...168,072,511
JBrowse link
G Dpm2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:1329091|PMID:9724629)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:9724629 PMID:21873635 GO_REF:0000119 MGI:1329091 MGI:4834177 MGI:6201960 NCBI chr 2:32,460,870...32,463,583
Ensembl chr 2:32,460,870...32,463,591
JBrowse link
G Dpm3 dolichyl-phosphate mannosyltransferase polypeptide 3 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000119 MGI:4834177 MGI:6201960 NCBI chr 3:89,166,567...89,174,386
Ensembl chr 3:89,166,665...89,174,386
JBrowse link
G Gpaa1 GPI anchor attachment protein 1 acts_upstream_of_or_within ISS (MGI:1340145|PMID:10393431) MGI PMID:10393431 MGI:1340145 NCBI chr15:76,215,494...76,219,099
Ensembl chr15:76,215,431...76,219,107
JBrowse link
G Mppe1 metallophosphoesterase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:67,358,119...67,378,901
Ensembl chr18:67,358,114...67,378,901
JBrowse link
G Pgap1 post-GPI attachment to proteins 1 involved_in ISO RGD
MGI
PMID:14734546 GO_REF:0000096 MGI:4417868 RGD:1303970 NCBI chr 1:54,512,159...54,596,843
Ensembl chr 1:54,512,153...54,596,843
JBrowse link
G Pgap2 post-GPI attachment to proteins 2 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 MGI:6201960 NCBI chr 7:101,859,153...101,887,771
Ensembl chr 7:101,859,415...101,887,774
JBrowse link
G Pgap3 post-GPI attachment to proteins 3 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000119 MGI:4834177 MGI:6201960 NCBI chr11:98,279,498...98,292,022
Ensembl chr11:98,279,503...98,291,316
JBrowse link
G Pgap4 post-GPI attachment to proteins GalNAc transferase 4 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000119 MGI:4834177 MGI:6201960 NCBI chr 4:49,584,506...49,597,876
Ensembl chr 4:49,584,506...49,597,876
JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:80283|PMID:8611683)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:8611683 PMID:21873635 MGI:6201960 MGI:80283 NCBI chr  X:163,202,814...163,216,912
Ensembl chr  X:163,202,783...163,216,912
JBrowse link
G Pigb phosphatidylinositol glycan anchor biosynthesis, class B involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000119 MGI:4834177 MGI:6201960 NCBI chr 9:72,920,639...72,946,973
Ensembl chr 9:72,914,701...72,947,660
JBrowse link
G Pigc phosphatidylinositol glycan anchor biosynthesis, class C involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:161,796,757...161,801,029
Ensembl chr 1:161,796,755...161,801,004
JBrowse link
G Pigf phosphatidylinositol glycan anchor biosynthesis, class F involved_in IDA
IBA
ISO
(MGI:1860649|PMID:10781593)
(MGI:6201960|PMID:21873635)
UniProt
GO_Central
MGI
PMID:10781593 PMID:21873635 GO_REF:0000119 MGI:1860649 MGI:4834177 MGI:6201960 NCBI chr17:87,304,686...87,332,972
Ensembl chr17:87,304,684...87,332,834
JBrowse link
G Pigg phosphatidylinositol glycan anchor biosynthesis, class G acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:3576398|PMID:15632136)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:15632136 PMID:21873635 MGI:3576398 MGI:6201960 NCBI chr 5:108,460,679...108,497,225
Ensembl chr 5:108,460,475...108,497,221
JBrowse link
G Pigh phosphatidylinositol glycan anchor biosynthesis, class H involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000119 MGI:4834177 MGI:6201960 NCBI chr12:79,127,443...79,136,478
Ensembl chr12:79,127,438...79,136,425
JBrowse link
G Pigk phosphatidylinositol glycan anchor biosynthesis, class K acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr 3:152,419,718...152,548,705
Ensembl chr 3:152,419,737...152,686,045
JBrowse link
G Pigl phosphatidylinositol glycan anchor biosynthesis, class L involved_in ISO RGD
MGI
PMID:9188481 GO_REF:0000096 MGI:4417868 RGD:729509 NCBI chr11:62,349,267...62,406,863
Ensembl chr11:62,349,286...62,405,243
JBrowse link
G Pigm phosphatidylinositol glycan anchor biosynthesis, class M involved_in ISO
IBA
(MGI:6201960|PMID:21873635) RGD
GO_Central
MGI
PMID:11226175 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:70624 NCBI chr 1:172,204,098...172,211,666
Ensembl chr 1:172,204,113...172,211,666
JBrowse link
G Pign phosphatidylinositol glycan anchor biosynthesis, class N involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 1:105,446,147...105,591,466
Ensembl chr 1:105,446,147...105,591,402
JBrowse link
G Pigo phosphatidylinositol glycan anchor biosynthesis, class O involved_in IDA
IBA
(MGI:1860649|PMID:10781593)
(MGI:6201960|PMID:21873635)
UniProt
GO_Central
PMID:10781593 PMID:21873635 MGI:1860649 MGI:6201960 NCBI chr 4:43,016,964...43,026,369
Ensembl chr 4:43,017,635...43,025,819
JBrowse link
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P acts_upstream_of_or_within
involved_in
IMP
IBA
ISO
(MGI:3804747|PMID:10944123)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:10944123 PMID:21873635 GO_REF:0000119 MGI:3804747 MGI:4834177 MGI:6201960 NCBI chr16:94,159,622...94,171,874
Ensembl chr16:94,159,622...94,172,701
JBrowse link
G Pigq phosphatidylinositol glycan anchor biosynthesis, class Q acts_upstream_of_or_within
involved_in
IMP
IBA
ISO
IGI
(MGI:1339481|PMID:10373468)
(MGI:6201960|PMID:21873635)
(MGI:1307040|PMID:9729469)
MGI
GO_Central
PMID:9729469 PMID:10373468 PMID:21873635 GO_REF:0000119 MGI:1307040 MGI:1339481 MGI:4834177 MGI:6201960 NCBI chr17:26,145,398...26,161,855
Ensembl chr17:26,145,395...26,163,910
JBrowse link
G Pigs phosphatidylinositol glycan anchor biosynthesis, class S acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr11:78,219,272...78,233,602
Ensembl chr11:78,219,241...78,233,608
JBrowse link
G Pigt phosphatidylinositol glycan anchor biosynthesis, class T acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr 2:164,339,461...164,350,221
Ensembl chr 2:164,339,440...164,350,221
JBrowse link
G Pigu phosphatidylinositol glycan anchor biosynthesis, class U involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:155,120,163...155,199,344
Ensembl chr 2:155,120,163...155,199,350
JBrowse link
G Pigv phosphatidylinositol glycan anchor biosynthesis, class V involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000119 MGI:4834177 MGI:6201960 NCBI chr 4:133,387,071...133,401,498
Ensembl chr 4:133,387,698...133,399,958
JBrowse link
G Pigw phosphatidylinositol glycan anchor biosynthesis, class W involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr11:84,767,139...84,771,111
Ensembl chr11:84,767,141...84,771,111
JBrowse link
G Pigx phosphatidylinositol glycan anchor biosynthesis, class X involved_in
acts_upstream_of_or_within
IEA UniProt GO_REF:0000002 GO_REF:0000043 MGI:1354194 MGI:2152098 NCBI chr16:31,903,234...31,918,545
Ensembl chr16:31,903,234...31,918,558
JBrowse link
G Pigyl phosphatidylinositol glycan anchor biosynthesis, class Y-like involved_in
acts_upstream_of_or_within
IBA
ISO
(MGI:6201960|PMID:21873635)
(PMID:16162815)
GO_Central
MGI
PMID:16162815 PMID:21873635 MGI:6201960 NCBI chr 9:22,068,142...22,069,651
Ensembl chr 9:22,068,142...22,069,654
JBrowse link
G Pigz phosphatidylinositol glycan anchor biosynthesis, class Z involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000119 MGI:4834177 MGI:6201960 NCBI chr16:31,745,797...31,764,866
Ensembl chr16:31,752,669...31,764,864
JBrowse link
G Pyurf Pigy upstream reading frame acts_upstream_of_or_within ISA (MGI:3699386|PMID:16162815) MGI PMID:16162815 MGI:3699386 NCBI chr 6:57,661,724...57,669,063
Ensembl chr 6:57,663,561...57,669,063
JBrowse link
G Slc30a5 solute carrier family 30 (zinc transporter), member 5 acts_upstream_of_positive_effect ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:100,939,153...100,969,988
Ensembl chr13:100,939,156...100,969,935
JBrowse link
GPI anchor release term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpep1 dipeptidase 1 involved_in ISO (PMID:17615681) UniProt PMID:17615681 NCBI chr 8:123,913,069...123,928,551
Ensembl chr 8:123,912,981...123,928,551
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in
acts_upstream_of_or_within
IGI
IBA
ISO
IDA
(MGI:5447609|PMID:17720976)
(MGI:6201960|PMID:21873635)
(MGI:3583476|PMID:15946906), (MGI:3703397|PMID:16822939)
(MGI:1097182|PMID:9716655)
UniProt
GO_Central
MGI
PMID:9716655 PMID:15946906 PMID:16822939 PMID:17720976 PMID:21873635 GO_REF:0000119 MGI:1097182 MGI:3583476 MGI:3703397 MGI:4834177 MGI:5447609 MGI:6201960 NCBI chr13:25,127,135...25,175,919
Ensembl chr13:25,127,135...25,176,484
JBrowse link
G Notum notum palmitoleoyl-protein carboxylesterase NOT|involved_in IDA (MGI:5640887|PMID:25771893) UniProt PMID:25771893 MGI:5640887 NCBI chr11:120,544,614...120,552,019
Ensembl chr11:120,544,614...120,552,001
JBrowse link
preassembly of GPI anchor in ER membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pigl phosphatidylinositol glycan anchor biosynthesis, class L involved_in ISO MGI GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 NCBI chr11:62,349,267...62,406,863
Ensembl chr11:62,349,286...62,405,243
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28558
    metabolic process 10986
      organic substance metabolic process 10547
        carbohydrate derivative metabolic process 1098
          liposaccharide metabolic process 102
            glycolipid metabolic process 101
              GPI anchor metabolic process 36
                GPI anchor biosynthetic process + 33
                GPI anchor release 3
                mannosyl diphosphorylinositol ceramide metabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 28558
    metabolic process 10986
      cellular metabolic process 9649
        phosphorus metabolic process 1906
          organophosphate metabolic process 1025
            phospholipid metabolic process 375
              glycerophospholipid metabolic process 283
                phosphatidylinositol metabolic process 155
                  GPI anchor metabolic process 36
                    GPI anchor biosynthetic process + 33
                    GPI anchor release 3
                    mannosyl diphosphorylinositol ceramide metabolic process 0
paths to the root