ONTOLOGY REPORT - ANNOTATIONS
Term: N-glycan processing
Accession: GO:0006491
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Definition: The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking.
Synonyms: exact_synonym: N-linked glycoprotein maturation
narrow_synonym: glycoprotein trimming involved in glycoprotein maturation
alt_id: GO:0006492
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Engase
endo-beta-N-acetylglucosaminidase
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr10:103,707,169...103,719,833
Ensembl chr10:103,707,169...103,719,819
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Fut8
fucosyltransferase 8
acts_upstream_of_or_within
ISO IEA
(PMID:24619415) GO_REF:0000107
RGD Ensembl
PMID:24619415
GO_REF:0000107
NCBI chr 6:101,682,354...101,909,784
Ensembl chr 6:95,949,991...96,176,677
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Ganab
glucosidase II alpha subunit
involved_in
ISO IBA IEA
(PMID:10929008) GO_REF:0000033 (PMID:27462106) GO_REF:0000107
RGD GO_Central Ensembl
PMID:10929008 PMID:27462106
GO_REF:0000033 GO_REF:0000107
NCBI chr 1:205,793,910...205,813,704
Ensembl chr 1:205,793,895...205,813,695
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Ganc
glucosidase, alpha; neutral C
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 3:107,353,369...107,406,104
Ensembl chr 3:107,353,369...107,405,241
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Hexa
hexosaminidase subunit alpha
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 8:68,832,524...68,857,462
Ensembl chr 8:59,936,660...59,962,013
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Hexb
hexosaminidase subunit beta
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 2:30,218,608...30,238,771
Ensembl chr 2:28,484,012...28,504,223
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Man2a1
mannosidase, alpha, class 2A, member 1
involved_in acts_upstream_of_or_within
IDA IBA ISO
PMID:1885615 GO_REF:0000033 MGI:2150656 (PMID:16754854)
GO_Central RGD
PMID:16754854 PMID:1885615
GO_REF:0000033, RGD:38501079
NCBI chr 9:111,698,913...111,855,257
Ensembl chr 9:104,252,001...104,408,349
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Man2a2
mannosidase, alpha, class 2A, member 2
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:134,304,714...134,327,611
Ensembl chr 1:134,306,236...134,327,315
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Mgat4a
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
involved_in
ISS ISO
GO_REF:0000024 (PMID:16377570)
UniProt RGD
PMID:16377570
GO_REF:0000024
NCBI chr 9:39,673,427...39,786,747
Ensembl chr 9:39,673,430...39,766,890
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Prkcsh
PRKCSH beta subunit of glucosidase II
involved_in
ISO IBA
(PMID:10929008) GO_REF:0000033
RGD GO_Central
PMID:10929008
GO_REF:0000033
NCBI chr 8:28,810,836...28,822,503
Ensembl chr 8:20,534,880...20,546,492
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St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 4:177,513,966...177,651,553
Ensembl chr 4:175,789,947...175,920,708
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St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
involved_in
ISO IBA IEA
(PMID:10766765) GO_REF:0000033 GO_REF:0000107
RGD GO_Central Ensembl
PMID:10766765
GO_REF:0000033 GO_REF:0000107
NCBI chr 1:127,762,573...127,838,017
Ensembl chr 1:127,762,573...127,838,091
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St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
involved_in
ISO IBA IEA
(PMID:10766765), (PMID:26192331) GO_REF:0000033 GO_REF:0000107
RGD GO_Central Ensembl
PMID:10766765 PMID:26192331
GO_REF:0000033 GO_REF:0000107
NCBI chr18:57,754,349...57,760,839
Ensembl chr18:57,754,347...57,760,839
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St8sia4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
involved_in
ISO IBA IEA
(PMID:10766765) GO_REF:0000033 GO_REF:0000107
RGD GO_Central Ensembl
PMID:10766765
GO_REF:0000033 GO_REF:0000107
NCBI chr 9:103,437,479...103,532,008
Ensembl chr 9:95,993,503...96,084,653
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St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr18:70,736,395...70,802,537
Ensembl chr18:70,736,602...70,797,789
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Gnptab
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
involved_in
ISO IBA IEA
(PMID:19938078), (PMID:25505245) GO_REF:0000033 GO_REF:0000107
RGD GO_Central Ensembl
PMID:19938078 PMID:25505245
GO_REF:0000033 GO_REF:0000107
NCBI chr 7:22,800,502...22,866,336
Ensembl chr 7:22,800,485...22,866,933
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