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ONTOLOGY REPORT - ANNOTATIONS


Term:N-glycan processing
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Accession:GO:0006491 term browser browse the term
Definition:The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking.
Synonyms:exact_synonym: N-linked glycoprotein maturation
 narrow_synonym: glycoprotein trimming involved in glycoprotein maturation
 alt_id: GO:0006492



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N-glycan processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fut8 fucosyltransferase 8 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5613435|PMID:24619415)
Ensembl
RGD
PMID:24619415 GO_REF:0000107 MGI:5613435 NCBI chr 6:95,949,246...96,176,677
Ensembl chr 6:95,949,991...96,176,677
JBrowse link
G Ganab glucosidase II alpha subunit involved_in ISO
IBA
(PMID:10929008)
(MGI:6158858|PMID:27462106)
GO_REF:0000033
RGD
GO_Central
PMID:10929008 PMID:27462106 GO_REF:0000033 MGI:6158858 NCBI chr 1:205,793,910...205,813,704
Ensembl chr 1:205,793,895...205,813,695
JBrowse link
G Ganc glucosidase, alpha; neutral C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:107,353,369...107,406,104
Ensembl chr 3:107,353,369...107,405,241
JBrowse link
G Gnptg N-acetylglucosamine-1-phosphate transferase subunit gamma involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr10:14,252,186...14,257,128
Ensembl chr10:14,251,136...14,257,096
JBrowse link
G Man2a1 mannosidase, alpha, class 2A, member 1 involved_in
acts_upstream_of_or_within
IDA
ISO
IEA
IBA
PMID:1885615
MGI:2150656 (MGI:3652665|PMID:16754854)
GO_REF:0000118
GO_REF:0000033
RGD
TreeGrafter
GO_Central
PMID:16754854 PMID:1885615 GO_REF:0000033 GO_REF:0000118 MGI:3652665, RGD:38501079 NCBI chr 9:104,252,001...104,408,349
Ensembl chr 9:104,252,001...104,408,349
JBrowse link
G Man2a2 mannosidase, alpha, class 2A, member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:134,304,714...134,327,611
Ensembl chr 1:134,306,236...134,327,315
JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389
JBrowse link
G Mgat4a alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A involved_in ISO
ISS
(MGI:3696712|PMID:16377570)
GO_REF:0000024
RGD
UniProt
PMID:16377570 GO_REF:0000024 MGI:3696712 NCBI chr 9:39,673,427...39,786,747
Ensembl chr 9:39,673,430...39,766,890
JBrowse link
G Prkcsh PRKCSH beta subunit of glucosidase II involved_in ISO
IBA
(PMID:10929008)
GO_REF:0000033
RGD
GO_Central
PMID:10929008 GO_REF:0000033 NCBI chr 8:20,534,787...20,546,493
Ensembl chr 8:20,534,880...20,546,492
JBrowse link
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708
JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in ISO
IBA
(PMID:10766765)
GO_REF:0000033
RGD
GO_Central
PMID:10766765 GO_REF:0000033 NCBI chr 1:127,762,573...127,838,017
Ensembl chr 1:127,762,573...127,838,091
JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in ISO
IBA
(PMID:10766765), (PMID:26192331)
GO_REF:0000033
RGD
GO_Central
PMID:10766765 PMID:26192331 GO_REF:0000033 NCBI chr18:57,754,349...57,760,839
Ensembl chr18:57,754,347...57,760,839
JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in ISO
IBA
(PMID:10766765)
GO_REF:0000033
RGD
GO_Central
PMID:10766765 GO_REF:0000033 NCBI chr 9:95,990,131...96,084,661
Ensembl chr 9:95,993,503...96,084,653
JBrowse link
G St8sia5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:70,736,395...70,802,537
Ensembl chr18:70,736,602...70,797,789
JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:76,740,755...76,884,178
Ensembl chr17:76,745,224...76,884,299
JBrowse link
N-glycan processing to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in ISO
IBA
(PMID:19938078), (PMID:25505245)
GO_REF:0000033
RGD
GO_Central
PMID:19938078 PMID:25505245 GO_REF:0000033 NCBI chr 7:22,800,502...22,866,336
Ensembl chr 7:22,800,485...22,866,933
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20325
    metabolic process 11737
      primary metabolic process 10282
        protein metabolic process 4706
          glycoprotein metabolic process 387
            N-glycan processing 16
              Golgi apparatus mannose trimming 0
              N-glycan diversification 0
              N-glycan processing to lysosome 1
              N-glycan processing to secreted and cell-surface N-glycans 0
Path 2
Term Annotations click to browse term
  biological_process 20325
    metabolic process 11737
      organic substance metabolic process 11231
        macromolecule metabolic process 9483
          protein metabolic process 4706
            glycoprotein metabolic process 387
              N-glycan processing 16
                Golgi apparatus mannose trimming 0
                N-glycan diversification 0
                N-glycan processing to lysosome 1
                N-glycan processing to secreted and cell-surface N-glycans 0
paths to the root