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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular protein modification process
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Accession:GO:0006464 term browser browse the term
Definition:The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
Synonyms:broad_synonym: protein modification process
 related_synonym: process resulting in protein modification;   protein tagging activity


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    Path 1
    Term Annotations click to browse term
      biological_process 19610
        metabolic process 11878
          cellular metabolic process 10831
            cellular macromolecule metabolic process 8304
              cellular protein metabolic process 5295
                cellular protein modification process 3653
                  ISG15-protein conjugation 5
                  N-terminal protein amino acid modification + 30
                  actin modification + 4
                  attachment of GPI anchor to protein 5
                  charged-tRNA amino acid modification + 1
                  co-translational protein modification + 3
                  histone modification + 504
                  metal incorporation into metallo-molybdopterin complex + 1
                  metal incorporation into metallo-oxygen cluster + 0
                  metal incorporation into metallo-sulfur cluster + 2
                  negative regulation of protein modification process + 565
                  nucleic acid-protein covalent cross-linking + 1
                  peptide cross-linking + 36
                  peptidyl-amino acid modification + 1314
                  positive regulation of protein modification process + 1039
                  post-translational protein modification + 25
                  protein ADP-ribosylation + 38
                  protein acylation + 257
                  protein alkylation + 205
                  protein amidation + 1
                  protein arginylation 2
                  protein biotinylation + 1
                  protein carbamoylation + 0
                  protein carboxylation + 3
                  protein de-ADP-ribosylation + 6
                  protein deacylation + 123
                  protein dealkylation + 33
                  protein deamination + 1
                  protein deglutathionylation 0
                  protein deglycation + 2
                  protein deglycosylation + 12
                  protein dehydration + 0
                  protein delipidation 1
                  protein denucleotidylation + 1
                  protein dephosphorylation + 316
                  protein desulfurization 0
                  protein esterification + 0
                  protein flavinylation 0
                  protein glucuronidation + 1
                  protein glutathionylation + 2
                  protein glycosylation + 215
                  protein halogenation + 0
                  protein hydroxylation + 31
                  protein initiator methionine removal + 3
                  protein lipidation + 91
                  protein modification by small protein conjugation or removal + 952
                  protein nitrosylation + 18
                  protein nucleotidylation + 2
                  protein oxidation + 14
                  protein phosphopantetheinylation + 1
                  protein phosphorylation + 1633
                  protein polyamination + 0
                  protein prenylation + 12
                  protein sialylation 6
                  protein sulfation + 6
                  protein sulfhydration + 1
                  protein tyrosinylation + 1
                  protein-FAD linkage + 1
                  protein-FMN linkage + 0
                  protein-chromophore linkage + 10
                  protein-coenzyme A linkage + 0
                  protein-pyridoxal-5-phosphate linkage + 1
                  protein-tetrapyrrole linkage + 1
                  regulation of protein modification process + 1624
                  sulfur incorporation into metallo-sulfur cluster 0
                  trans-translation-dependent protein tagging 0
    Path 2
    Term Annotations click to browse term
      biological_process 19610
        metabolic process 11878
          organic substance metabolic process 11408
            macromolecule metabolic process 9863
              protein metabolic process 5967
                protein modification process 3653
                  cellular protein modification process 3653
                    ISG15-protein conjugation 5
                    N-terminal protein amino acid modification + 30
                    actin modification + 4
                    attachment of GPI anchor to protein 5
                    charged-tRNA amino acid modification + 1
                    co-translational protein modification + 3
                    histone modification + 504
                    metal incorporation into metallo-molybdopterin complex + 1
                    metal incorporation into metallo-oxygen cluster + 0
                    metal incorporation into metallo-sulfur cluster + 2
                    negative regulation of protein modification process + 565
                    nucleic acid-protein covalent cross-linking + 1
                    peptide cross-linking + 36
                    peptidyl-amino acid modification + 1314
                    positive regulation of protein modification process + 1039
                    post-translational protein modification + 25
                    protein ADP-ribosylation + 38
                    protein acylation + 257
                    protein alkylation + 205
                    protein amidation + 1
                    protein arginylation 2
                    protein biotinylation + 1
                    protein carbamoylation + 0
                    protein carboxylation + 3
                    protein de-ADP-ribosylation + 6
                    protein deacylation + 123
                    protein dealkylation + 33
                    protein deamination + 1
                    protein deglutathionylation 0
                    protein deglycation + 2
                    protein deglycosylation + 12
                    protein dehydration + 0
                    protein delipidation 1
                    protein denucleotidylation + 1
                    protein dephosphorylation + 316
                    protein desulfurization 0
                    protein esterification + 0
                    protein flavinylation 0
                    protein glucuronidation + 1
                    protein glutathionylation + 2
                    protein glycosylation + 215
                    protein halogenation + 0
                    protein hydroxylation + 31
                    protein initiator methionine removal + 3
                    protein lipidation + 91
                    protein modification by small protein conjugation or removal + 952
                    protein nitrosylation + 18
                    protein nucleotidylation + 2
                    protein oxidation + 14
                    protein phosphopantetheinylation + 1
                    protein phosphorylation + 1633
                    protein polyamination + 0
                    protein prenylation + 12
                    protein sialylation 6
                    protein sulfation + 6
                    protein sulfhydration + 1
                    protein tyrosinylation + 1
                    protein-FAD linkage + 1
                    protein-FMN linkage + 0
                    protein-chromophore linkage + 10
                    protein-coenzyme A linkage + 0
                    protein-pyridoxal-5-phosphate linkage + 1
                    protein-tetrapyrrole linkage + 1
                    regulation of protein modification process + 1624
                    sulfur incorporation into metallo-sulfur cluster 0
                    trans-translation-dependent protein tagging 0
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