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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA aminoacylation for protein translation
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Accession:GO:0006418 term browser browse the term
Definition:The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.
Synonyms:narrow_synonym: tRNA charging
 xref: MetaCyc:TRNA-CHARGING-PWY

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tRNA aminoacylation for protein translation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr25:55,334,669...55,367,257
Ensembl chr25:55,332,340...55,367,248 		JBrowse link
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr25:9,534,747...9,618,119
Ensembl chr25:9,534,114...9,618,141 		JBrowse link
G GARS1 glycyl-tRNA synthetase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr21:27,750,532...27,791,143
Ensembl chr21:27,749,514...27,790,881 		JBrowse link
G PARS2 prolyl-tRNA synthetase 2, mitochondrial involved_in IEA UniProt GO_REF:0000117 NCBI chr20:78,172,890...78,180,901
Ensembl chr20:78,178,634...78,180,061 		JBrowse link
G TARS1 threonyl-tRNA synthetase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr 4:32,670,020...32,697,608
Ensembl chr 4:32,670,203...32,699,168 		JBrowse link
G TARS2 threonyl-tRNA synthetase 2, mitochondrial involved_in IEA UniProt GO_REF:0000117
G TARS3 threonyl-tRNA synthetase 3 involved_in IEA UniProt GO_REF:0000117 NCBI chr29:20,106,215...20,198,227
Ensembl chr29:20,105,747...20,185,159 		JBrowse link
alanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS1 alanyl-tRNA synthetase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:16906134) RGD
TreeGrafter
MGI
InterPro		 PMID:2040280 PMID:16906134 GO_REF:0000002 GO_REF:0000118 RGD:2302982 NCBI chr 5:53,399,717...53,433,472
Ensembl chr 5:53,395,638...53,433,461 		JBrowse link
G AARS2 alanyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr17:27,855,688...27,869,427
Ensembl chr17:27,855,713...27,870,409 		JBrowse link
G LOC103243378 alanyl-tRNA editing protein Aarsd1 involved_in IEA InterPro GO_REF:0000002 NCBI chr16:63,323,110...63,337,167
Ensembl chr16:63,322,885...63,339,596 		JBrowse link
arginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DALRD3 DALR anticodon binding domain containing 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr22:10,415,833...10,419,492
Ensembl chr22:10,411,353...10,419,770 		JBrowse link
G RARS1 arginyl-tRNA synthetase 1 involved_in ISO
IEA		 RGD
TreeGrafter
InterPro		 PMID:7082655 GO_REF:0000002 GO_REF:0000118 RGD:2303394 NCBI chr23:70,711,435...70,746,000
Ensembl chr23:70,711,016...70,745,884 		JBrowse link
G RARS2 arginyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr13:11,995,422...12,068,150
Ensembl chr13:11,995,453...12,068,138 		JBrowse link
asparaginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NARS1 asparaginyl-tRNA synthetase 1 involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr18:22,107,287...22,129,378
Ensembl chr18:22,107,291...22,131,140 		JBrowse link
G NARS2 asparaginyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 1:69,647,713...69,778,390
Ensembl chr 1:69,643,531...69,778,361 		JBrowse link
aspartyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS1 aspartyl-tRNA synthetase 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr10:20,120,999...20,202,019
Ensembl chr10:20,119,914...20,201,991 		JBrowse link
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr25:55,334,669...55,367,257
Ensembl chr25:55,332,340...55,367,248 		JBrowse link
cysteinyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARS1 cysteinyl-tRNA synthetase 1 involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:2,812,169...2,871,835
Ensembl chr 1:2,812,016...2,871,800 		JBrowse link
G CARS2 cysteinyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 3:88,871,338...88,929,454
Ensembl chr 3:88,871,460...88,929,436 		JBrowse link
glutaminyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LARS1 leucyl-tRNA synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:48,691,361...48,761,664
Ensembl chr23:48,677,622...48,761,596 		JBrowse link
G QARS1 glutaminyl-tRNA synthetase 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr22:10,497,921...10,507,673
Ensembl chr22:10,497,658...10,507,325 		JBrowse link
glutamyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EARS2 glutamyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:21,248,866...21,282,725
Ensembl chr 5:21,251,224...21,282,966 		JBrowse link
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr25:9,534,747...9,618,119
Ensembl chr25:9,534,114...9,618,141 		JBrowse link
glycyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GARS1 glycyl-tRNA synthetase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19470612) InterPro
MGI		 PMID:19470612 GO_REF:0000002 NCBI chr21:27,750,532...27,791,143
Ensembl chr21:27,749,514...27,790,881 		JBrowse link
histidyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HARS1 histidyl-tRNA synthetase 1 involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr23:43,307,573...43,324,140
Ensembl chr23:43,307,415...43,323,767 		JBrowse link
G HARS2 histidyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr23:43,323,847...43,333,620
Ensembl chr23:43,323,892...43,331,401 		JBrowse link
isoleucyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IARS1 isoleucyl-tRNA synthetase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:8052601) MGI
TreeGrafter
Ensembl
InterPro		 PMID:8052601 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr12:102,745,155...102,819,638
Ensembl chr12:102,744,569...102,819,603 		JBrowse link
G IARS2 isoleucyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr25:9,414,316...9,485,542
Ensembl chr25:9,414,711...9,485,429 		JBrowse link
leucyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LARS1 leucyl-tRNA synthetase 1 involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr23:48,691,361...48,761,664
Ensembl chr23:48,677,622...48,761,596 		JBrowse link
G LARS2 leucyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr22:6,861,105...7,021,325
Ensembl chr22:6,861,006...7,020,009 		JBrowse link
lysyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KARS1 lysyl-tRNA synthetase 1 involved_in ISO
IEA		 RGD
TreeGrafter
InterPro
Ensembl		 PMID:7082655 PMID:7372681 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:2303393 RGD:2303394 NCBI chr 5:61,113,215...61,133,093
Ensembl chr 5:61,113,213...61,132,995 		JBrowse link
methionyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MARS1 methionyl-tRNA synthetase 1 involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr11:53,397,380...53,410,596 JBrowse link
G MARS2 methionyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr10:83,186,370...83,193,464
Ensembl chr10:83,187,344...83,189,125 		JBrowse link
mitochondrial alanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS2 alanyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,855,688...27,869,427
Ensembl chr17:27,855,713...27,870,409 		JBrowse link
mitochondrial asparaginyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial involved_in ISO (PMID:23275545) UniProt PMID:23275545 NCBI chr25:55,334,669...55,367,257
Ensembl chr25:55,332,340...55,367,248 		JBrowse link
mitochondrial glycyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GARS1 glycyl-tRNA synthetase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:27,750,532...27,791,143
Ensembl chr21:27,749,514...27,790,881 		JBrowse link
mitochondrial seryl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SARS2 seryl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:33,536,160...33,552,160
Ensembl chr 6:33,536,498...33,552,000 		JBrowse link
mitochondrial tryptophanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WARS2 tryptophanyl tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:14,614,902...14,726,630
Ensembl chr20:14,615,349...14,726,780 		JBrowse link
mitochondrial tyrosyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G YARS2 tyrosyl-tRNA synthetase 2 involved_in ISO (PMID:20598274) BHF-UCL PMID:20598274 NCBI chr11:32,181,214...32,192,654
Ensembl chr11:32,181,397...32,192,454 		JBrowse link
phenylalanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:66,356,479...66,921,276
Ensembl chr17:66,543,452...66,898,446 		JBrowse link
G FARSA phenylalanyl-tRNA synthetase subunit alpha involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:11,602,352...11,613,851
Ensembl chr 6:11,600,516...11,613,345 		JBrowse link
G FARSB phenylalanyl-tRNA synthetase subunit beta involved_in IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000117 GO_REF:0000118 NCBI chr10:108,492,463...108,568,226
Ensembl chr10:108,492,652...108,568,293 		JBrowse link
G LRRC47 leucine rich repeat containing 47 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:127,881,446...127,896,138
Ensembl chr20:127,881,473...127,895,959 		JBrowse link
prolyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr25:9,534,747...9,618,119
Ensembl chr25:9,534,114...9,618,141 		JBrowse link
G PARS2 prolyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr20:78,172,890...78,180,901
Ensembl chr20:78,178,634...78,180,061 		JBrowse link
seryl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SARS1 seryl-tRNA synthetase 1 involved_in ISO (PMID:24095058), (PMID:36041817)
(PMID:28236339), (PMID:34570399)		 UniProt PMID:24095058 PMID:28236339 PMID:34570399 PMID:36041817
G SARS2 seryl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:33,536,160...33,552,160
Ensembl chr 6:33,536,498...33,552,000 		JBrowse link
threonyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TARS1 threonyl-tRNA synthetase 1 involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:32,670,020...32,697,608
Ensembl chr 4:32,670,203...32,699,168 		JBrowse link
G TARS2 threonyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118
G TARS3 threonyl-tRNA synthetase 3 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr29:20,106,215...20,198,227
Ensembl chr29:20,105,747...20,185,159 		JBrowse link
tRNA aminoacylation for mitochondrial protein translation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EARS2 glutamyl-tRNA synthetase 2, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:21,248,866...21,282,725
Ensembl chr 5:21,251,224...21,282,966 		JBrowse link
tryptophanyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WARS1 tryptophanyl-tRNA synthetase 1 involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr24:78,296,154...78,340,683
Ensembl chr24:78,295,741...78,339,732 		JBrowse link
G WARS2 tryptophanyl tRNA synthetase 2, mitochondrial involved_in IEA InterPro GO_REF:0000002 NCBI chr20:14,614,902...14,726,630
Ensembl chr20:14,615,349...14,726,780 		JBrowse link
tyrosyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103228400 tyrosine--tRNA ligase, mitochondrial-like involved_in IEA InterPro GO_REF:0000002 NCBI chr22:74,734,656...74,736,422 JBrowse link
G YARS1 tyrosyl-tRNA synthetase 1 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr20:100,050,717...100,096,719
Ensembl chr20:100,052,535...100,095,980 		JBrowse link
G YARS2 tyrosyl-tRNA synthetase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:32,181,214...32,192,654
Ensembl chr11:32,181,397...32,192,454 		JBrowse link
valyl-tRNA aminoacylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VARS1 valyl-tRNA synthetase 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr17:40,228,217...40,245,366
Ensembl chr17:40,228,938...40,245,287 		JBrowse link
G VARS2 valyl-tRNA synthetase 2, mitochondrial involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr17:41,537,842...41,550,063
Ensembl chr17:41,534,552...41,549,439 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17106
    cellular process 16633
      metabolic process 11190
        macromolecule metabolic process 9238
          macromolecule biosynthetic process 6727
            translation 772
              tRNA aminoacylation for protein translation 42
                alanyl-tRNA aminoacylation + 3
                arginyl-tRNA aminoacylation + 3
                asparaginyl-tRNA aminoacylation + 3
                aspartyl-tRNA aminoacylation + 2
                cysteinyl-tRNA aminoacylation + 2
                glutaminyl-tRNA aminoacylation + 2
                glutamyl-tRNA aminoacylation + 2
                glycyl-tRNA aminoacylation + 1
                histidyl-tRNA aminoacylation + 2
                isoleucyl-tRNA aminoacylation + 2
                leucyl-tRNA aminoacylation + 2
                lysyl-tRNA aminoacylation + 1
                methionyl-tRNA aminoacylation + 2
                phenylalanyl-tRNA aminoacylation + 4
                prolyl-tRNA aminoacylation + 2
                seryl-tRNA aminoacylation + 2
                tRNA aminoacylation for mitochondrial protein translation + 7
                threonyl-tRNA aminoacylation + 3
                tryptophanyl-tRNA aminoacylation + 2
                tyrosyl-tRNA aminoacylation + 3
                valyl-tRNA aminoacylation + 2
Path 2
Term Annotations click to browse term
  biological_process 17106
    cellular process 16633
      metabolic process 11190
        primary metabolic process 10005
          nucleobase-containing compound metabolic process 5387
            nucleic acid metabolic process 4866
              RNA metabolic process 4326
                tRNA metabolic process 187
                  tRNA aminoacylation 45
                    tRNA aminoacylation for protein translation 42
                      alanyl-tRNA aminoacylation + 3
                      arginyl-tRNA aminoacylation + 3
                      asparaginyl-tRNA aminoacylation + 3
                      aspartyl-tRNA aminoacylation + 2
                      cysteinyl-tRNA aminoacylation + 2
                      glutaminyl-tRNA aminoacylation + 2
                      glutamyl-tRNA aminoacylation + 2
                      glycyl-tRNA aminoacylation + 1
                      histidyl-tRNA aminoacylation + 2
                      isoleucyl-tRNA aminoacylation + 2
                      leucyl-tRNA aminoacylation + 2
                      lysyl-tRNA aminoacylation + 1
                      methionyl-tRNA aminoacylation + 2
                      phenylalanyl-tRNA aminoacylation + 4
                      prolyl-tRNA aminoacylation + 2
                      seryl-tRNA aminoacylation + 2
                      tRNA aminoacylation for mitochondrial protein translation + 7
                      threonyl-tRNA aminoacylation + 3
                      tryptophanyl-tRNA aminoacylation + 2
                      tyrosyl-tRNA aminoacylation + 3
                      valyl-tRNA aminoacylation + 2
paths to the root