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ONTOLOGY REPORT - ANNOTATIONS


Term:mRNA cleavage
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Accession:GO:0006379 term browser browse the term
Definition:Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
Synonyms:related_synonym: cleavage stimulation factor activity



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mRNA cleavage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (MGI:6114871|PMID:25164867) RGD PMID:25164867 MGI:6114871 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Pcf11 PCF11 cleavage and polyadenylation factor subunit involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:146,694,045...146,724,030
Ensembl chr 1:146,697,646...146,724,124
JBrowse link
G Polr1h RNA polymerase I subunit H involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:1,594,936...1,598,854
Ensembl chr20:1,594,936...1,598,854
JBrowse link
G Polr2i RNA polymerase II subunit I involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:85,483,515...85,484,952
Ensembl chr 1:85,483,515...85,484,952
JBrowse link
mRNA cleavage involved in mRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (PMID:21317875) RGD PMID:21317875 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
positive regulation of mRNA cleavage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt21 nudix hydrolase 21 involved_in ISO
ISS
(PMID:15937220)
GO_REF:0000024
RGD
UniProt
PMID:15937220 GO_REF:0000024 NCBI chr19:10,974,800...10,993,841
Ensembl chr19:10,974,241...10,991,682
JBrowse link
pre-mRNA cleavage required for polyadenylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC096468.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr10:98,743,649...98,751,590 JBrowse link
G Cpsf2 cleavage and polyadenylation specific factor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:121,123,941...121,152,756
Ensembl chr 6:121,120,569...121,151,921
JBrowse link
G Cpsf4 cleavage and polyadenylation specific factor 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:9,429,765...9,445,582
Ensembl chr12:9,429,523...9,445,586
JBrowse link
G Cpsf6 cleavage and polyadenylation specific factor 6 involved_in ISO (PMID:20695905) RGD PMID:20695905 NCBI chr 7:52,956,589...53,001,783
Ensembl chr 7:52,956,589...52,988,122
JBrowse link
G Cpsf7 cleavage and polyadenylation specific factor 7 involved_in ISO
IBA
ISS
(PMID:20695905), (PMID:23187700)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:20695905 PMID:23187700 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:207,167,690...207,191,865
Ensembl chr 1:207,167,859...207,191,905
JBrowse link
G Cstf2 cleavage stimulation factor subunit 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:97,253,559...97,279,476
Ensembl chr  X:97,253,586...97,279,476
JBrowse link
G Cstf2t cleavage stimulation factor subunit 2, tau variant involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:228,952,617...228,956,183
Ensembl chr 1:228,952,504...228,955,873
JBrowse link
G Fip1l1 factor interacting with PAPOLA and CPSF1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:33,615,210...33,675,742
Ensembl chr14:33,617,720...33,675,708
JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 involved_in ISO
ISS
(PMID:9342333)
GO_REF:0000024
RGD
UniProt
PMID:9342333 GO_REF:0000024 NCBI chr 5:60,416,023...60,449,004
Ensembl chr 5:60,415,982...60,449,089
JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 involved_in ISO (PMID:9342333) RGD PMID:9342333 NCBI chr11:68,821,026...68,829,863
Ensembl chr11:68,817,740...68,851,885
JBrowse link
G Nudt21 nudix hydrolase 21 involved_in ISO (PMID:20695905) RGD PMID:20695905 NCBI chr19:10,974,800...10,993,841
Ensembl chr19:10,974,241...10,991,682
JBrowse link
G Tut1 terminal uridylyl transferase 1, U6 snRNA-specific involved_in ISO
ISS
(PMID:21102410)
GO_REF:0000024
RGD
UniProt
PMID:21102410 GO_REF:0000024 NCBI chr 1:205,848,691...205,859,767
Ensembl chr 1:205,848,772...205,859,764
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      primary metabolic process 10535
        nucleobase-containing compound metabolic process 5410
          nucleic acid metabolic process 4926
            RNA metabolic process 4397
              mRNA metabolic process 683
                mRNA cleavage 16
                  mRNA cleavage involved in mRNA processing + 13
                  negative regulation of mRNA cleavage 0
                  positive regulation of mRNA cleavage 1
                  regulation of mRNA cleavage + 1
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      cellular metabolic process 10719
        cellular aromatic compound metabolic process 5635
          nucleobase-containing compound metabolic process 5410
            nucleic acid metabolic process 4926
              RNA metabolic process 4397
                mRNA metabolic process 683
                  mRNA cleavage 16
                    mRNA cleavage involved in mRNA processing + 13
                    negative regulation of mRNA cleavage 0
                    positive regulation of mRNA cleavage 1
                    regulation of mRNA cleavage + 1
paths to the root