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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA modification
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Accession:GO:0006304 term browser browse the term
Definition:The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.



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DNA modification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO positive regulation of DNA adduct formation RGD PMID:24025706 RGD:7829724 NCBI chr2A:38,087,863...38,096,529
Ensembl chr2A:38,851,000...38,859,824
JBrowse link
G DNTT DNA nucleotidylexotransferase involved_in IEA UniProt GO_REF:0000043 NCBI chr10:92,916,783...92,958,216
Ensembl chr10:96,423,819...96,457,742
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase involved_in IEA UniProt GO_REF:0000117 NCBI chr10:126,059,701...126,365,850
Ensembl chr10:130,305,485...130,609,422
JBrowse link
G TREX1 three prime repair exonuclease 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5566725|PMID:24205360) MGI
Ensembl
PMID:24205360 GO_REF:0000107 MGI:5566725 NCBI chr 3:48,387,762...48,389,693
Ensembl chr 3:49,470,222...49,471,331
JBrowse link
C-5 methylation of cytosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha involved_in IEA GOC
Ensembl
GO_REF:0000107 GO_REF:0000108 NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605
JBrowse link
G DNMT3B DNA methyltransferase 3 beta acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5811689|PMID:27856912) MGI
Ensembl
GOC
PMID:27856912 GO_REF:0000107 GO_REF:0000108 MGI:5811689 NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487
JBrowse link
G DNMT3L DNA methyltransferase 3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:30,503,194...30,520,237 JBrowse link
G STPG4 sperm-tail PG-rich repeat containing 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5762940|PMID:23560077) MGI
Ensembl
PMID:23560077 GO_REF:0000107 MGI:5762940 NCBI chr2A:47,201,536...47,271,253
Ensembl chr2A:48,131,547...48,199,596
JBrowse link
chromatin reprogramming in the zygote term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL23 methyltransferase like 23 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:70,803,797...70,809,702
Ensembl chr17:76,370,184...76,375,727
JBrowse link
DNA ADP-ribosylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G PARP2 poly(ADP-ribose) polymerase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:1,215,727...1,230,006
Ensembl chr14:19,269,046...19,282,853
JBrowse link
G PARP3 poly(ADP-ribose) polymerase family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:51,883,695...51,890,266
Ensembl chr 3:53,112,494...53,119,053
JBrowse link
DNA cytosine deamination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 ISO RGD PMID:12697753 RGD:1358271 NCBI chr12:7,777,734...7,793,960
Ensembl chr12:7,939,262...7,944,203
JBrowse link
G APOBEC3A apolipoprotein B mRNA editing enzyme catalytic subunit 3A involved_in ISO (PMID:16527742), (PMID:21123384)
(PMID:20062055)
UniProt PMID:16527742 PMID:20062055 PMID:21123384 NCBI chr22:19,866,522...19,872,836 JBrowse link
G APOBEC3D apolipoprotein B mRNA editing enzyme catalytic subunit 3D involved_in ISO (PMID:21835787) UniProt PMID:21835787 NCBI chr22:19,931,452...19,942,829 JBrowse link
G APOBEC3F apolipoprotein B mRNA editing enzyme catalytic subunit 3F involved_in ISO (PMID:21835787) UniProt PMID:21835787 NCBI chr22:19,950,036...19,966,002 JBrowse link
G APOBEC3G apolipoprotein B mRNA editing enzyme catalytic subunit 3G involved_in ISS UniProt GO_REF:0000024 NCBI chr22:19,977,184...19,994,769 JBrowse link
G APOBEC3H apolipoprotein B mRNA editing enzyme catalytic subunit 3H involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:20,003,585...20,010,741
Ensembl chr22:37,821,315...37,828,153
JBrowse link
G CDADC1 cytidine and dCMP deaminase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:30,386,671...30,432,112
Ensembl chr13:49,138,498...49,186,541
JBrowse link
DNA dealkylation involved in DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH1 alkB homolog 1, histone H2A dioxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:58,227,094...58,262,107
Ensembl chr14:77,428,033...77,462,905
JBrowse link
G ALKBH2 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,664,678...106,670,558
Ensembl chr12:110,058,507...110,063,946
JBrowse link
G ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr11:43,841,083...43,880,608
Ensembl chr11:44,336,655...44,376,057
JBrowse link
G ASCC3 activating signal cointegrator 1 complex subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:98,345,023...98,720,332
Ensembl chr 6:102,224,820...102,599,521
JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr16:33,939,300...34,343,419
Ensembl chr16:53,023,425...53,490,231
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:50172|PMID:1554415) RGD
Ensembl
MGI
PMID:1554415 PMID:15025514 GO_REF:0000107 MGI:50172 RGD:2316914 NCBI chr10:126,059,701...126,365,850
Ensembl chr10:130,305,485...130,609,422
JBrowse link
DNA deamination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXOSC3 exosome component 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:37,611,173...37,634,869
Ensembl chr 9:38,552,659...38,558,078
JBrowse link
G EXOSC5 exosome component 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:38,379,884...38,391,309
Ensembl chr19:46,886,326...46,897,703
JBrowse link
G EXOSC6 exosome component 6 involved_in ISO (PMID:21255825) UniProt PMID:21255825 NCBI chr16:54,763,706...54,766,443 JBrowse link
DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AICDA activation induced cytidine deaminase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:8,688,392...8,699,008
Ensembl chr12:8,904,273...8,913,917
JBrowse link
G ALKBH1 alkB homolog 1, histone H2A dioxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:58,227,094...58,262,107
Ensembl chr14:77,428,033...77,462,905
JBrowse link
G ALKBH4 alkB homolog 4, lysine demethylase involved_in ISO (MGI:6323482|PMID:30982744) UniProt PMID:30982744 MGI:6323482 NCBI chr 7:94,596,641...94,605,369 JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr14:1,329,745...1,332,315
Ensembl chr14:19,381,911...19,384,542
JBrowse link
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 involved_in ISO (MGI:5285126|PMID:21496894) UniProt PMID:21496894 MGI:5285126 NCBI chr12:7,777,734...7,793,960
Ensembl chr12:7,939,262...7,944,203
JBrowse link
G APOBEC2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,641,211...40,652,975
Ensembl chr 6:41,950,194...41,963,086
JBrowse link
G APOBEC3A apolipoprotein B mRNA editing enzyme catalytic subunit 3A involved_in ISO (PMID:21496894) UniProt PMID:21496894 NCBI chr22:19,866,522...19,872,836 JBrowse link
G APOBEC3C apolipoprotein B mRNA editing enzyme catalytic subunit 3C involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:19,924,116...19,930,771
Ensembl chr22:37,743,388...37,749,725
JBrowse link
G APOBEC3F apolipoprotein B mRNA editing enzyme catalytic subunit 3F involved_in ISO (PMID:21496894) UniProt PMID:21496894 NCBI chr22:19,950,036...19,966,002 JBrowse link
G EOMES eomesodermin involved_in ISO (MGI:6220563|PMID:30186101) MGI PMID:30186101 MGI:6220563 NCBI chr 3:27,601,829...27,608,701
Ensembl chr 3:27,925,086...27,930,274
JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:33,939,300...34,343,419
Ensembl chr16:53,023,425...53,490,231
JBrowse link
G PAX6 paired box 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474
JBrowse link
G TDG thymine DNA glycosylase involved_in ISO (MGI:5287540|PMID:21817016)
(MGI:5141157|PMID:21722948), (MGI:5487523|PMID:21278727)
UniProt PMID:21278727 PMID:21722948 PMID:21817016 MGI:5141157 MGI:5287540 MGI:5487523 NCBI chr12:101,543,945...101,567,035
Ensembl chr12:104,938,519...104,961,284
JBrowse link
G TET1 tet methylcytosine dioxygenase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4822076|PMID:20639862) MGI
UniProt
InterPro
Ensembl
PMID:20639862 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 MGI:4822076 NCBI chr10:65,036,313...65,168,051
Ensembl chr10:67,586,586...67,703,160
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4822076|PMID:20639862) MGI
Ensembl
InterPro
UniProt
PMID:20639862 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 MGI:4822076 NCBI chr 4:97,612,439...97,745,544
Ensembl chr 4:108,269,082...108,358,400
JBrowse link
G TET3 tet methylcytosine dioxygenase 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4822076|PMID:20639862), (MGI:5525037|PMID:23690950) MGI
InterPro
UniProt
Ensembl
PMID:20639862 PMID:23690950 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 MGI:4822076 MGI:5525037 NCBI chr2A:74,058,948...74,180,046
Ensembl chr2A:75,568,636...75,682,701
JBrowse link
DNA demethylation of male pronucleus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL23 methyltransferase like 23 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6103984|PMID:28930672) UniProt
Ensembl
PMID:28930672 GO_REF:0000107 MGI:6103984 NCBI chr17:70,803,797...70,809,702
Ensembl chr17:76,370,184...76,375,727
JBrowse link
G STPG4 sperm-tail PG-rich repeat containing 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:6103984|PMID:28930672) Ensembl
UniProt
PMID:28930672 GO_REF:0000107 MGI:6103984 NCBI chr2A:47,201,536...47,271,253
Ensembl chr2A:48,131,547...48,199,596
JBrowse link
G TET3 tet methylcytosine dioxygenase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:74,058,948...74,180,046
Ensembl chr2A:75,568,636...75,682,701
JBrowse link
DNA hypermethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:21682946 RGD:9588311 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G MORC1 MORC family CW-type zinc finger 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5694015|PMID:25503965) MGI
Ensembl
PMID:25503965 GO_REF:0000107 MGI:5694015 NCBI chr 3:106,091,990...106,251,790
Ensembl chr 3:113,021,874...113,180,331
JBrowse link
DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF7IP activating transcription factor 7 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:14,373,084...14,504,286
Ensembl chr12:14,789,794...14,900,411
JBrowse link
G BAZ2A bromodomain adjacent to zinc finger domain 2A involved_in ISO (MGI:3587127|PMID:16085498), (MGI:3852588|PMID:19578370) UniProt PMID:16085498 PMID:19578370 MGI:3587127 MGI:3852588 NCBI chr12:32,274,240...32,313,839
Ensembl chr12:32,529,634...32,566,248
JBrowse link
G BEND3 BEN domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:104,875,201...104,926,926
Ensembl chr 6:108,745,993...108,778,116
JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5522578|PMID:24105743) MGI
Ensembl
PMID:24105743 GO_REF:0000107 MGI:5522578 NCBI chr10:22,477,755...22,487,894 JBrowse link
G CTCF CCCTC-binding factor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5522578|PMID:24105743)
(MGI:2450195|PMID:12461525)
MGI
Ensembl
PMID:12461525 PMID:24105743 GO_REF:0000107 MGI:2450195 MGI:5522578 NCBI chr16:47,906,503...47,983,271
Ensembl chr16:67,302,952...67,372,041
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:29115507 RGD:25823175 NCBI chr15:53,664,968...53,672,277
Ensembl chr15:73,284,566...73,290,636
JBrowse link
G DNMT1 DNA methyltransferase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2152690|PMID:11399088)
(MGI:6151717|PMID:27841881)
(MGI:5522578|PMID:24105743), (MGI:5888829|PMID:27892467)
(MGI:3655888|PMID:16887828)
MGI
Ensembl
PMID:11399088 PMID:16887828 PMID:24105743 PMID:27841881 PMID:27892467 GO_REF:0000107 MGI:2152690 MGI:3655888 MGI:5522578 MGI:5888829 MGI:6151717 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2152692|PMID:11399089), (MGI:2178074|PMID:11934864)
(MGI:6151717|PMID:27841881)
(MGI:3768461|PMID:17938196)
MGI
InterPro
Ensembl
PMID:11399089 PMID:11934864 PMID:17938196 PMID:27841881 GO_REF:0000002 GO_REF:0000107 MGI:2152692 MGI:2178074 MGI:3768461 MGI:6151717 NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605
JBrowse link
G DNMT3B DNA methyltransferase 3 beta acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3623538|PMID:16543361)
(MGI:6151717|PMID:27841881)
(MGI:3768461|PMID:17938196)
(MGI:5320860|PMID:22133874)
MGI
InterPro
PMID:16543361 PMID:17938196 PMID:22133874 PMID:27841881 GO_REF:0000002 MGI:3623538 MGI:3768461 MGI:5320860 MGI:6151717 NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487
JBrowse link
G DNMT3L DNA methyltransferase 3 like acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5694015|PMID:25503965) MGI
InterPro
Ensembl
PMID:25503965 GO_REF:0000002 GO_REF:0000107 MGI:5694015 NCBI chr21:30,503,194...30,520,237 JBrowse link
G EHMT1 euchromatic histone lysine methyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:108,724,568...108,951,077
Ensembl chr 9:137,764,950...137,895,564
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,542,946...31,560,894
Ensembl chr 6:32,429,271...32,451,844
JBrowse link
G EOMES eomesodermin involved_in ISO (MGI:6220563|PMID:30186101) MGI PMID:30186101 MGI:6220563 NCBI chr 3:27,601,829...27,608,701
Ensembl chr 3:27,925,086...27,930,274
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5522578|PMID:24105743) MGI
Ensembl
PMID:24105743 GO_REF:0000107 MGI:5522578 NCBI chr 7:140,536,962...140,613,104
Ensembl chr 7:153,017,590...153,059,726
JBrowse link
G HELLS helicase, lymphoid specific acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2153312|PMID:11711429) MGI
Ensembl
PMID:11711429 GO_REF:0000107 MGI:2153312 NCBI chr10:91,282,330...91,344,156
Ensembl chr10:94,790,292...94,847,209
JBrowse link
G HEMK1 HemK methyltransferase family member 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:50,494,129...50,521,637
Ensembl chr 3:51,732,404...51,747,791
JBrowse link
G KMT2A lysine methyltransferase 2A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3625774|PMID:16618927) MGI
Ensembl
PMID:16618927 GO_REF:0000107 MGI:3625774 NCBI chr11:113,273,198...113,364,404 JBrowse link
G KMT2E lysine methyltransferase 2E (inactive) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:97,001,250...97,099,956
Ensembl chr 7:109,734,808...109,832,851
JBrowse link
G LOC100978090 protein ALEX involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,204,188...55,206,608
Ensembl chr20:56,474,459...56,621,747
JBrowse link
G LOC100990650 guanine nucleotide-binding protein G(s) subunit alpha acts_upstream_of_or_within ISO (MGI:4454202|PMID:20427744) MGI PMID:20427744 MGI:4454202 NCBI chr20:55,190,607...55,262,245 JBrowse link
G MTA2 metastasis associated 1 family member 2 acts_upstream_of_or_within ISO (MGI:4888087|PMID:20720167) MGI PMID:20720167 MGI:4888087 NCBI chr11:57,950,770...57,959,615
Ensembl chr11:61,305,373...61,324,592
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (MGI:5512657|PMID:24074862) UniProt PMID:24074862 MGI:5512657 NCBI chr 5:8,195,868...8,228,071
Ensembl chr 5:8,017,403...8,049,322
JBrowse link
G PAX6 paired box 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474
JBrowse link
G PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:54,698,338...54,761,889
Ensembl chr17:59,824,566...59,887,015
JBrowse link
G SPOCD1 SPOC domain containing 1 involved_in ISO (MGI:6453929|PMID:32674113) UniProt PMID:32674113 MGI:6453929 NCBI chr 1:31,074,169...31,100,378 JBrowse link
G TEX15 testis expressed 15, meiosis and synapsis associated involved_in ISO (MGI:6434559|PMID:32381626), (MGI:6447460|PMID:32719317) UniProt PMID:32381626 PMID:32719317 MGI:6434559 MGI:6447460 NCBI chr 8:30,145,628...30,232,903
Ensembl chr 8:27,334,129...27,420,049
JBrowse link
DNA methylation involved in embryo development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 acts_upstream_of_or_within
involved_in
acts_upstream_of_or_within_positive_effect
ISO
IEA
(MGI:49689|PMID:1606615)
(MGI:6151717|PMID:27841881)
(MGI:6270117|PMID:29117290)
MGI
Ensembl
PMID:1606615 PMID:27841881 PMID:29117290 GO_REF:0000107 MGI:49689 MGI:6151717 MGI:6270117 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1347183|PMID:10555141)
(MGI:6151717|PMID:27841881)
(MGI:5014027|PMID:20385583)
MGI
Ensembl
PMID:10555141 PMID:20385583 PMID:27841881 GO_REF:0000107 MGI:1347183 MGI:5014027 MGI:6151717 NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605
JBrowse link
G DNMT3B DNA methyltransferase 3 beta acts_upstream_of_or_within ISO (MGI:1347183|PMID:10555141)
(MGI:6151717|PMID:27841881)
(PMID:18814855)
MGI
UniProt
PMID:10555141 PMID:18814855 PMID:27841881 MGI:1347183 MGI:6151717 NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487
JBrowse link
G TRIM28 tripartite motif containing 28 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5319411|PMID:22495301) MGI
Ensembl
PMID:22495301 GO_REF:0000107 MGI:5319411 NCBI chr19:55,557,130...55,563,802
Ensembl chr19:64,371,477...64,377,144
JBrowse link
G ZDBF2 zinc finger DBF-type containing 2 acts_upstream_of_or_within ISO (MGI:6151717|PMID:27841881) MGI PMID:27841881 MGI:6151717 NCBI chr2B:93,516,875...93,556,652
Ensembl chr2B:211,645,765...211,685,047
JBrowse link
G ZFP57 ZFP57 zinc finger protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6506156|PMID:33500348) MGI
Ensembl
PMID:33500348 GO_REF:0000107 MGI:6506156 NCBI chr 6:29,476,459...29,485,480
Ensembl chr 6:30,134,263...30,143,045
JBrowse link
DNA methylation involved in gamete generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:109,330,983...109,397,864
Ensembl chr 7:122,025,611...122,091,923
JBrowse link
G CTCFL CCCTC-binding factor like involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:53,836,295...53,865,974
Ensembl chr20:55,114,405...55,143,717
JBrowse link
G DDX4 DEAD-box helicase 4 involved_in ISO (MGI:4443217|PMID:20439430) UniProt PMID:20439430 MGI:4443217 NCBI chr 5:58,202,037...58,286,518
Ensembl chr 5:59,827,031...59,910,681
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605
JBrowse link
G DNMT3L DNA methyltransferase 3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:30,503,194...30,520,237 JBrowse link
G FKBP6 FKBP prolyl isomerase family member 6 (inactive) involved_in ISO (MGI:5439219|PMID:22902560) UniProt PMID:22902560 MGI:5439219 Ensembl chr 7:80,481,443...80,511,813 JBrowse link
G KDM1B lysine demethylase 1B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4358629|PMID:19727073) MGI
Ensembl
PMID:19727073 GO_REF:0000107 MGI:4358629 NCBI chr 6:18,002,763...18,071,598
Ensembl chr 6:18,355,907...18,425,552
JBrowse link
G MAEL maelstrom spermatogenic transposon silencer involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:142,341,646...142,442,521
Ensembl chr 1:146,195,482...146,228,669
JBrowse link
G MORC1 MORC family CW-type zinc finger 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5694015|PMID:25503965) MGI
Ensembl
PMID:25503965 GO_REF:0000107 MGI:5694015 NCBI chr 3:106,091,990...106,251,790
Ensembl chr 3:113,021,874...113,180,331
JBrowse link
G MOV10L1 Mov10 like RISC complex RNA helicase 1 involved_in ISO (MGI:4457283|PMID:20534472) UniProt PMID:20534472 MGI:4457283 NCBI chr22:30,320,202...30,391,121
Ensembl chr22:49,319,203...49,389,765
JBrowse link
G PIWIL2 piwi like RNA-mediated gene silencing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:21,520,166...21,608,374
Ensembl chr 8:18,463,173...18,544,186
JBrowse link
G PIWIL4 piwi like RNA-mediated gene silencing 4 involved_in ISO (MGI:3778312|PMID:18381894), (MGI:3815367|PMID:18922463) UniProt PMID:18381894 PMID:18922463 MGI:3778312 MGI:3815367 NCBI chr11:89,572,252...89,628,251
Ensembl chr11:93,097,709...93,150,981
JBrowse link
G PLD6 phospholipase D family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,084,634...34,091,470
Ensembl chr17:39,016,859...39,023,398
JBrowse link
G PRMT7 protein arginine methyltransferase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:48,687,324...48,734,883
Ensembl chr16:68,086,620...68,127,953
JBrowse link
G TDRD1 tudor domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:110,778,772...110,832,545
Ensembl chr10:114,210,165...114,262,386
JBrowse link
G TDRD12 tudor domain containing 12 involved_in ISO (MGI:5516419|PMID:24067652) UniProt PMID:24067652 MGI:5516419 NCBI chr19:29,638,686...29,750,249
Ensembl chr19:38,386,557...38,489,791
JBrowse link
G TDRD5 tudor domain containing 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:155,080,083...155,171,734
Ensembl chr 1:158,761,013...158,852,660
JBrowse link
G TDRD9 tudor domain containing 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:84,553,807...84,677,904
Ensembl chr14:104,388,558...104,483,552
JBrowse link
G TDRKH tudor and KH domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:127,128,857...127,149,197
Ensembl chr 1:130,774,515...130,792,942
JBrowse link
DNA methylation on adenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL4 methyltransferase 4, N6-adenosine involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:11,711,502...11,745,222
Ensembl chr18:14,018,279...14,051,974
JBrowse link
G N6AMT1 N-6 adenine-specific DNA methyltransferase 1 NOT|involved_in ISO
IEA
(PMID:30392959), (PMID:31632689), (PMID:31636962) UniProt
Ensembl
PMID:30392959 PMID:31632689 PMID:31636962 GO_REF:0000107 NCBI chr21:15,303,430...15,316,596
Ensembl chr21:28,694,294...28,704,745
JBrowse link
DNA methylation on cytosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:49689|PMID:1606615) RGD
UniProt
Ensembl
MGI
PMID:1606615 PMID:22880885 GO_REF:0000107 GO_REF:0000117 MGI:49689 RGD:9588218 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha involved_in ISO
IEA
RGD
UniProt
PMID:22880885 GO_REF:0000117 RGD:9588218 NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605
JBrowse link
G DNMT3B DNA methyltransferase 3 beta involved_in IEA UniProt GO_REF:0000117 NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487
JBrowse link
G DNMT3L DNA methyltransferase 3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:30,503,194...30,520,237 JBrowse link
DNA methylation on cytosine within a CG sequence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:3856245 RGD:2301219 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3718157|PMID:17212651) MGI
Ensembl
PMID:17212651 GO_REF:0000107 MGI:3718157 NCBI chr 6:31,542,946...31,560,894
Ensembl chr 6:32,429,271...32,451,844
JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO (MGI:3610843|PMID:16287714) MGI PMID:16287714 MGI:3610843 NCBI chr19:10,515,216...10,616,155
Ensembl chr19:11,250,006...11,334,952
JBrowse link
hypermethylation of CpG island term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3A DNA methyltransferase 3 alpha involved_in ISO (MGI:5009774|PMID:21047779) BHF-UCL PMID:21047779 MGI:5009774 NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605
JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:39,118,330...39,130,768
Ensembl chr19:47,710,197...47,726,948
JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in ISO (MGI:5009774|PMID:21047779) BHF-UCL PMID:21047779 MGI:5009774 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:47,301,245...47,326,891
Ensembl chr11:47,853,991...47,880,259
JBrowse link
hypomethylation of CpG island term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5607719|PMID:20961378) MGI
Ensembl
PMID:20961378 GO_REF:0000107 MGI:5607719 NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747
JBrowse link
negative regulation of DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPPA3 developmental pluripotency associated 3 involved_in ISO (MGI:5432962|PMID:22722204), (MGI:5447615|PMID:17143267), (MGI:5465527|PMID:21407207) UniProt PMID:17143267 PMID:21407207 PMID:22722204 MGI:5432962 MGI:5447615 MGI:5465527 NCBI chr12:7,834,298...7,841,064 JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:3046385|PMID:15087456) MGI PMID:15087456 MGI:3046385 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272
JBrowse link
G TRIM28 tripartite motif containing 28 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5319411|PMID:22495301) MGI
Ensembl
PMID:22495301 GO_REF:0000107 MGI:5319411 NCBI chr19:55,557,130...55,563,802
Ensembl chr19:64,371,477...64,377,144
JBrowse link
negative regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3L DNA methyltransferase 3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:30,503,194...30,520,237 JBrowse link
G KMT2A lysine methyltransferase 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:113,273,198...113,364,404 JBrowse link
oxidative DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH2 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,664,678...106,670,558
Ensembl chr12:110,058,507...110,063,946
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:97,612,439...97,745,544
Ensembl chr 4:108,269,082...108,358,400
JBrowse link
oxidative single-stranded DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr11:43,841,083...43,880,608
Ensembl chr11:44,336,655...44,376,057
JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chr16:33,939,300...34,343,419
Ensembl chr16:53,023,425...53,490,231
JBrowse link
positive regulation of DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTUD4 OTU deubiquitinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:137,480,809...137,527,651
Ensembl chr 4:149,135,900...149,182,476
JBrowse link
G STPG4 sperm-tail PG-rich repeat containing 4 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr2A:47,201,536...47,271,253
Ensembl chr2A:48,131,547...48,199,596
JBrowse link
G TOX thymocyte selection associated high mobility group box involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:55,246,933...55,553,839
Ensembl chr 8:56,922,773...57,219,410
JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:7,825,332...7,895,095
Ensembl chr16:9,065,858...9,106,146
JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:33,535,543...33,683,220
Ensembl chr  X:41,232,041...41,379,910
JBrowse link
positive regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3L DNA methyltransferase 3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:30,503,194...30,520,237 JBrowse link
G MECP2 methyl-CpG binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:143,571,864...143,647,192
Ensembl chr  X:153,465,204...153,527,854
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G WT1 WT1 transcription factor acts_upstream_of
involved_in
ISO
IEA
(PMID:23042785) ARUK-UCL
Ensembl
PMID:23042785 GO_REF:0000107 NCBI chr11:32,349,807...32,398,494
Ensembl chr11:32,238,720...32,287,249
JBrowse link
protection of DNA demethylation of female pronucleus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPPA3 developmental pluripotency associated 3 involved_in ISO (MGI:5432962|PMID:22722204), (MGI:5447615|PMID:17143267), (MGI:5465527|PMID:21407207) UniProt PMID:17143267 PMID:21407207 PMID:22722204 MGI:5432962 MGI:5447615 MGI:5465527 NCBI chr12:7,834,298...7,841,064 JBrowse link
regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAZ2A bromodomain adjacent to zinc finger domain 2A involved_in ISO (MGI:2389510|PMID:12368916) ComplexPortal PMID:12368916 MGI:2389510 NCBI chr12:32,274,240...32,313,839
Ensembl chr12:32,529,634...32,566,248
JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 ISO RGD PMID:22880885 RGD:9588218 NCBI chr 6:31,542,946...31,560,894
Ensembl chr 6:32,429,271...32,451,844
JBrowse link
G GRHL2 grainyhead like transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:98,129,147...98,308,120
Ensembl chr 8:100,308,575...100,471,830
JBrowse link
G KDM1B lysine demethylase 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,002,763...18,071,598
Ensembl chr 6:18,355,907...18,425,552
JBrowse link
G MBD1 methyl-CpG binding domain protein 1 ISO RGD PMID:20735989 RGD:9588647 NCBI chr18:43,647,395...43,662,266
Ensembl chr18:46,996,905...47,009,831
JBrowse link
G MBD2 methyl-CpG binding domain protein 2 ISO RGD PMID:20735989 RGD:9588647 NCBI chr18:47,534,356...47,609,481 JBrowse link
G MBD3 methyl-CpG binding domain protein 3 ISO RGD PMID:20735989 RGD:9588647 Ensembl chr19:1,549,184...1,559,254 JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:20735989 RGD:9588647 NCBI chr  X:143,571,864...143,647,192
Ensembl chr  X:153,465,204...153,527,854
JBrowse link
G MIS18A MIS18 kinetochore protein A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5438906|PMID:22516971) MGI
Ensembl
PMID:22516971 GO_REF:0000107 MGI:5438906 NCBI chr21:18,635,735...18,646,611
Ensembl chr21:32,016,547...32,027,430
JBrowse link
G MPHOSPH8 M-phase phosphoprotein 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:932,620...999,853
Ensembl chr13:19,278,149...19,316,389
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:23260200 RGD:10413908 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G PRDM14 PR/SET domain 14 acts_upstream_of_or_within ISO (MGI:5506832|PMID:23670199) MGI PMID:23670199 MGI:5506832 NCBI chr 8:66,578,674...66,599,360
Ensembl chr 8:68,240,741...68,260,263
JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO RGD PMID:22041901 RGD:9491827 NCBI chr14:3,737,741...3,746,646
Ensembl chr14:21,836,984...21,846,018
JBrowse link
G RLF RLF zinc finger acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5693990|PMID:25857663) MGI
Ensembl
PMID:25857663 GO_REF:0000107 MGI:5693990 NCBI chr 1:39,448,869...39,528,061
Ensembl chr 1:40,773,638...40,852,218
JBrowse link
G SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:135,874,888...135,917,096
Ensembl chr 4:147,174,060...147,214,809
JBrowse link
G TET1 tet methylcytosine dioxygenase 1 acts_upstream_of_or_within ISO (MGI:4939073|PMID:21295276) MGI PMID:21295276 MGI:4939073 NCBI chr10:65,036,313...65,168,051
Ensembl chr10:67,586,586...67,703,160
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5607719|PMID:20961378) MGI
Ensembl
PMID:20961378 GO_REF:0000107 MGI:5607719 NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747
JBrowse link
G ZNF595 zinc finger protein 595 acts_upstream_of_or_within ISO (MGI:5442238|PMID:22801370) MGI PMID:22801370 MGI:5442238 NCBI chr 4:50,243...92,219 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15332
    metabolic process 10016
      organic substance metabolic process 9632
        macromolecule metabolic process 8273
          macromolecule modification 3433
            DNA modification 108
              DNA ADP-ribosylation 3
              DNA alkylation + 75
              DNA dealkylation + 28
              DNA deamination + 10
              DNA methylation or demethylation + 94
              DNA restriction-modification system 0
              base J metabolic process 0
              depurination 0
              depyrimidination 0
Path 2
Term Annotations click to browse term
  biological_process 15332
    metabolic process 10016
      cellular metabolic process 8332
        cellular nitrogen compound metabolic process 5494
          nucleobase-containing compound metabolic process 4737
            nucleic acid metabolic process 4328
              DNA metabolic process 905
                DNA modification 108
                  DNA ADP-ribosylation 3
                  DNA alkylation + 75
                  DNA dealkylation + 28
                  DNA deamination + 10
                  DNA methylation or demethylation + 94
                  DNA restriction-modification system 0
                  base J metabolic process 0
                  depurination 0
                  depyrimidination 0
paths to the root