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ONTOLOGY REPORT - ANNOTATIONS


Term:base-excision repair, gap-filling
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Accession:GO:0006287 term browser browse the term
Definition:Repair of the damaged strand by the combined action of an apurinic endouclease that degrades a few bases on the damaged strand and a polymerase that synthesizes a 'patch' in the 5' to 3' direction, using the undamaged strand as a template.



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base-excision repair, gap-filling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC020909.1 novel protein involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr19:50,415,799...50,428,409 JBrowse link
G ADPRS ADP-ribosylserine hydrolase involved_in TAS Reactome Reactome:R-HSA-110373 NCBI chr 1:36,088,892...36,093,932
Ensembl chr 1:36,088,892...36,093,932
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 involved_in TAS Reactome Reactome:R-HSA-73933 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
JBrowse link
G BPHL biphenyl hydrolase like involved_in TAS Reactome Reactome:R-HSA-110373 NCBI chr 6:3,118,376...3,153,578
Ensembl chr 6:3,118,374...3,153,578
JBrowse link
G FEN1 flap structure-specific endonuclease 1 involved_in TAS Reactome Reactome:R-HSA-110373 NCBI chr11:61,792,911...61,797,238
Ensembl chr11:61,792,911...61,797,238
JBrowse link
G LIG1 DNA ligase 1 involved_in TAS Reactome Reactome:R-HSA-110373 NCBI chr19:48,115,445...48,170,344
Ensembl chr19:48,115,445...48,170,603
JBrowse link
G LIG3 DNA ligase 3 involved_in TAS Reactome Reactome:R-HSA-5649702 NCBI chr17:34,980,512...35,010,872
Ensembl chr17:34,980,512...35,009,743
JBrowse link
G NEIL1 nei like DNA glycosylase 1 involved_in TAS Reactome Reactome:R-HSA-5649702 NCBI chr15:75,347,039...75,357,115
Ensembl chr15:75,346,955...75,357,115
JBrowse link
G PARG poly(ADP-ribose) glycohydrolase involved_in TAS Reactome Reactome:R-HSA-110373 NCBI chr10:49,818,279...49,942,027
Ensembl chr10:49,818,279...49,970,203
JBrowse link
G PCNA proliferating cell nuclear antigen involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15177179) Ensembl
MGI
PMID:15177179 GO_REF:0000107 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in TAS Reactome Reactome:R-HSA-5649702 NCBI chr19:49,861,204...49,867,576
Ensembl chr19:49,859,882...49,878,351
JBrowse link
G POLB DNA polymerase beta acts_upstream_of_or_within
involved_in
ISO
TAS
IEA
(PMID:15177179) RGD
MGI
Reactome
Ensembl
PMID:15177179 PMID:17412650 GO_REF:0000107 RGD:2302580 Reactome:R-HSA-110373 Reactome:R-HSA-110381 Reactome:R-HSA-5649702 NCBI chr 8:42,338,494...42,371,808
Ensembl chr 8:42,338,454...42,371,808
JBrowse link
G POLD1 DNA polymerase delta 1, catalytic subunit involved_in
acts_upstream_of_or_within
IDA
ISO
IEA
IBA
(PMID:10559260), (PMID:10559261)
(PMID:15177179)
UniProt
MGI
TreeGrafter
GO_Central
Ensembl
PMID:10559260 PMID:10559261 PMID:15177179 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr19:50,384,323...50,418,018
Ensembl chr19:50,384,204...50,418,018
JBrowse link
G POLE DNA polymerase epsilon, catalytic subunit involved_in IDA
IBA
IEA
(PMID:10559260) UniProt
GO_Central
TreeGrafter
PMID:10559260 GO_REF:0000033 GO_REF:0000118 NCBI chr12:132,623,762...132,687,342
Ensembl chr12:132,623,753...132,687,376
JBrowse link
G POLG DNA polymerase gamma, catalytic subunit acts_upstream_of_or_within IDA (PMID:15177179) MGI PMID:15177179 NCBI chr15:89,316,320...89,334,824
Ensembl chr15:89,305,198...89,334,861
JBrowse link
G POLL DNA polymerase lambda involved_in IDA (PMID:19806195) UniProt PMID:19806195 NCBI chr10:101,578,882...101,588,270
Ensembl chr10:101,578,882...101,588,270
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19770
    metabolic process 12509
      organic substance metabolic process 12005
        macromolecule metabolic process 10270
          nucleic acid metabolic process 5957
            DNA metabolic process 1100
              base-excision repair, gap-filling 16
Path 2
Term Annotations click to browse term
  biological_process 19770
    cellular process 18460
      cellular metabolic process 11168
        heterocycle metabolic process 6764
          nucleobase-containing compound metabolic process 6564
            nucleic acid metabolic process 5957
              DNA metabolic process 1100
                DNA repair 652
                  base-excision repair 53
                    base-excision repair, gap-filling 16
paths to the root