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ONTOLOGY REPORT - ANNOTATIONS


Term:base-excision repair, AP site formation
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Accession:GO:0006285 term browser browse the term
Definition:The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired.



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base-excision repair, AP site formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc5 ERCC excision repair 5, endonuclease involved_in ISO (PMID:9927729) RGD PMID:9927729 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472
JBrowse link
G Nthl1 nth-like DNA glycosylase 1 involved_in IBA
ISO
PMID:21873635
(PMID:15358233), (PMID:9927729)
RGD PMID:9927729 PMID:15358233 PMID:21873635 RGD:13792537 NCBI chr10:13,655,791...13,661,958
Ensembl chr10:13,655,785...13,661,957
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Tdg thymine-DNA glycosylase involved_in IBA
ISO
PMID:21873635
(PMID:11889051), (PMID:18512959)
RGD PMID:11889051 PMID:18512959 PMID:21873635 RGD:13792537 NCBI chr 7:21,077,853...21,097,617
Ensembl chr 7:21,077,853...21,097,567
JBrowse link
base-excision repair, AP site formation via deaminated base removal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ung uracil-DNA glycosylase involved_in ISO (PMID:18973764) RGD PMID:18973764 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    metabolic process 11461
      cellular metabolic process 9699
        cellular macromolecule metabolic process 3404
          DNA metabolic process 992
            base-excision repair, AP site formation 5
              base-excision repair, AP site formation via deaminated base removal 1
              depurination 0
              depyrimidination 0
Path 2
Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      cellular metabolic process 9699
        cellular nitrogen compound metabolic process 6419
          nucleobase-containing compound metabolic process 5336
            nucleic acid metabolic process 4845
              DNA metabolic process 992
                DNA repair 509
                  base-excision repair 43
                    base-excision repair, AP site formation 5
                      base-excision repair, AP site formation via deaminated base removal 1
                      depurination 0
                      depyrimidination 0
paths to the root