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ONTOLOGY REPORT - ANNOTATIONS


Term:RNA-dependent DNA biosynthetic process
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Accession:GO:0006278 term browser browse the term
Definition:A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand.


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RNA-dependent DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tert telomerase reverse transcriptase involved_in ISO (PMID:9398860) BHF-UCL PMID:9398860 NCBI chrNW_004936815:468,987...492,666 JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD shelterin complex subunit and telomerase recruitment factor involved_in ISO (PMID:15181449)
(PMID:15380063)
BHF-UCL PMID:15181449 PMID:15380063 NCBI chrNW_004936475:18,049,134...18,052,123 JBrowse link
G Ctc1 CST telomere replication complex component 1 involved_in ISO (PMID:22763445) BHF-UCL PMID:22763445 NCBI chrNW_004936595:1,456,911...1,476,331 JBrowse link
G Dcp2 decapping mRNA 2 involved_in ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chrNW_004936597:4,884,458...4,918,041 JBrowse link
G Exosc10 exosome component 10 involved_in ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chrNW_004936474:130,735...153,608 JBrowse link
G Gnl3l G protein nucleolar 3 like involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chrNW_004936751:1,423,822...1,457,257 JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) BHF-UCL PMID:23935072 NCBI chrNW_004936512:11,481,017...11,487,737 JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chrNW_004936880:368,041...425,967 JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chrNW_004936526:6,014,745...6,022,213 JBrowse link
G Nat10 N-acetyltransferase 10 involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chrNW_004936533:3,870,795...3,911,498 JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:23657261) BHF-UCL PMID:23657261 NCBI chrNW_004936471:25,165,850...25,173,503 JBrowse link
G Pinx1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in ISO (PMID:21119197)
(PMID:11701125)
BHF-UCL PMID:11701125 PMID:21119197 NCBI chrNW_004936675:2,641,851...2,706,201 JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:19567472) UniProt PMID:19567472 NCBI chrNW_004936471:33,135,186...33,173,218 JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:15181449) BHF-UCL PMID:15181449 NCBI chrNW_004936605:836,824...919,099 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chrNW_004936561:3,826,802...3,844,406 JBrowse link
G Stn1 STN1 subunit of CST complex involved_in ISO (PMID:22763445) BHF-UCL PMID:22763445 NCBI chrNW_004936600:2,230,754...2,266,956 JBrowse link
G Ten1 TEN1 subunit of CST complex involved_in ISO (PMID:22763445) BHF-UCL PMID:22763445 NCBI chrNW_004936594:1,139,926...1,159,611 JBrowse link
G Tent4b terminal nucleotidyltransferase 4B involved_in ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chrNW_004936475:3,266,763...3,328,209 JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO (PMID:11971978) BHF-UCL PMID:11971978 NCBI chrNW_004936648:1,809,395...1,835,890 JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:11971978)
(PMID:17055345)
BHF-UCL PMID:11971978 PMID:17055345 NCBI chrNW_004936475:19,469,501...19,498,494 JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 involved_in ISO (PMID:10581025)
(PMID:15133513)
BHF-UCL PMID:10581025 PMID:15133513 NCBI chrNW_004936722:320,171...323,703 JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD shelterin complex subunit and telomerase recruitment factor involved_in ISO (PMID:17237768) BHF-UCL PMID:17237768 NCBI chrNW_004936475:18,049,134...18,052,123 JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:5705431 NCBI chrNW_004936551:359,134...534,672 JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:5705431 NCBI chrNW_004936540:4,074,543...4,178,859 JBrowse link
G Aurkb aurora kinase B involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chrNW_004936595:1,435,601...1,437,423 JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chrNW_004936545:7,416,257...7,436,024 JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chrNW_004936580:5,537,338...5,554,384 JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chrNW_004936491:7,224,989...7,241,348 JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chrNW_004936643:2,354,799...2,368,048 JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chrNW_004936543:7,887,511...7,900,174 JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chrNW_004936491:17,017,687...17,033,526 JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chrNW_004936500:12,949,563...12,962,699 JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of ISO (MGI:5428344|PMID:22723415) BHF-UCL PMID:22723415 MGI:5428344 NCBI chrNW_004936473:29,999,542...30,034,610 JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 acts_upstream_of_or_within ISO (MGI:3047190|PMID:15240872) MGI PMID:15240872 MGI:3047190 NCBI chrNW_004936927:134,770...144,057 JBrowse link
G Fbxo4 F-box protein 4 involved_in ISO (PMID:16275645) BHF-UCL PMID:16275645 NCBI chrNW_004936518:855,304...873,927 JBrowse link
G Hmbox1 homeobox containing 1 involved_in ISO (PMID:23685356) BHF-UCL PMID:23685356 NCBI chrNW_004936675:1,578,705...1,741,283 JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) BHF-UCL PMID:23935072 NCBI chrNW_004936512:11,481,017...11,487,737 JBrowse link
G LOC101966755 polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chrNW_004936664:3,649,020...3,656,545 JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chrNW_004936588:4,882,191...4,891,807 JBrowse link
G Map3k4 mitogen-activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chrNW_004936489:11,908,083...11,972,186 JBrowse link
G Mapk1 mitogen-activated protein kinase 1 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chrNW_004936619:1,889,841...1,932,646 JBrowse link
G Mapk15 mitogen-activated protein kinase 15 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chrNW_004936470:8,420,850...8,425,996 JBrowse link
G Mapk3 mitogen-activated protein kinase 3 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chrNW_004936501:12,342,670...12,390,650 JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chrNW_004936558:4,414,283...4,448,291 JBrowse link
G Nek2 NIMA related kinase 2 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chrNW_004936557:1,683,027...1,695,410 JBrowse link
G Nek7 NIMA related kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chrNW_004936567:5,685,619...5,815,094 JBrowse link
G Parn poly(A)-specific ribonuclease involved_in ISO (PMID:26482878), (PMID:26950371) BHF-UCL PMID:26482878 PMID:26950371 NCBI chrNW_004936501:2,666,908...2,810,159 JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chrNW_004936802:1,130,341...1,236,715 JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:12768206), (PMID:12781132)
(PMID:17237768)
BHF-UCL PMID:12768206 PMID:12781132 PMID:17237768 NCBI chrNW_004936605:836,824...919,099 JBrowse link
G Prkcq protein kinase C theta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chrNW_004936484:8,048,239...8,166,058 JBrowse link
G Tcp1 t-complex 1 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chrNW_004936489:11,273,335...11,282,811 JBrowse link
G Tnks tankyrase involved_in ISO (PMID:12782650), (PMID:18221737)
(PMID:11739745)
BHF-UCL PMID:11739745 PMID:12782650 PMID:18221737 NCBI chrNW_004936573:788,909...993,453 JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:19188702) BHF-UCL PMID:19188702 NCBI chrNW_004936586:1,055,478...1,137,924 JBrowse link
regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:26586433) BHF-UCL PMID:26586433 NCBI chrNW_004936551:359,134...534,672 JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:26586433) BHF-UCL PMID:26586433 NCBI chrNW_004936605:836,824...919,099 JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:19864690)
(PMID:23685356)
BHF-UCL PMID:19864690 PMID:23685356 NCBI chrNW_004936475:19,469,501...19,498,494 JBrowse link
telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkc1 dyskerin pseudouridine synthase 1 involved_in ISO (PMID:23685356), (PMID:29695869)
(PMID:26950371)
UniProt
BHF-UCL
PMID:23685356 PMID:26950371 PMID:29695869 NCBI chrNW_004936927:134,770...144,057 JBrowse link
G Gar1 GAR1 ribonucleoprotein involved_in ISO (PMID:29695869) UniProt PMID:29695869 NCBI chrNW_004936563:1,006,475...1,014,808 JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO (PMID:10197982) BHF-UCL PMID:10197982 NCBI chrNW_004936835:316,767...321,999 JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISO (PMID:10197982) BHF-UCL PMID:10197982 NCBI chrNW_004936476:15,830,459...15,836,994 JBrowse link
G Nhp2 NHP2 ribonucleoprotein involved_in ISO (PMID:29695869) UniProt PMID:29695869 NCBI chrNW_004936647:520,542...525,226 JBrowse link
G Nop10 NOP10 ribonucleoprotein involved_in ISO (PMID:29695869) UniProt PMID:29695869 NCBI chrNW_004936673:2,829,599...2,830,407 JBrowse link
G Parp4 poly(ADP-ribose) polymerase family member 4 NOT|acts_upstream_of_or_within ISO (MGI:3045914|PMID:15169895) MGI PMID:15169895 MGI:3045914 NCBI chrNW_004936720:2,049,045...2,138,649 JBrowse link
G Pinx1 PIN2 (TERF1) interacting telomerase inhibitor 1 acts_upstream_of_or_within ISO (PMID:11701125) MGI PMID:11701125 NCBI chrNW_004936675:2,641,851...2,706,201 JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:12768206) UniProt PMID:12768206 NCBI chrNW_004936605:836,824...919,099 JBrowse link
G Ptges3 prostaglandin E synthase 3 involved_in ISO (PMID:19740745)
(MGI:5819359|PMID:10197982)
(PMID:10197982), (PMID:19740745)
BHF-UCL PMID:10197982 PMID:19740745 MGI:5819359 NCBI chrNW_004936646:969,674...990,532 JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in ISO (PMID:9705271) UniProt PMID:9705271 NCBI chrNW_004936647:2,546,100...2,637,524 JBrowse link
G Tep1 telomerase associated protein 1 NOT|acts_upstream_of_or_within ISO (MGI:3045914|PMID:15169895) MGI PMID:15169895 MGI:3045914 NCBI chrNW_004936877:575,264...613,965 JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO (PMID:9034193)
(PMID:23685356)
UniProt
BHF-UCL
PMID:9034193 PMID:23685356 NCBI chrNW_004936648:1,809,395...1,835,890 JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO (PMID:9454332)
(PMID:16043710), (PMID:17940095), (PMID:19701182), (PMID:21531765), (PMID:29695869), (PMID:9443919)
BHF-UCL
UniProt
PMID:9443919 PMID:9454332 PMID:16043710 PMID:17940095 PMID:19701182 More... NCBI chrNW_004936815:468,987...492,666 JBrowse link
G Wrap53 WD repeat containing antisense to TP53 involved_in ISO (PMID:23685356)
(PMID:23685356), (PMID:29695869), (PMID:29804836)
BHF-UCL
UniProt
PMID:23685356 PMID:29695869 PMID:29804836 NCBI chrNW_004936595:936,184...952,784 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12173
    metabolic process 7652
      biosynthetic process 3941
        cellular biosynthetic process 3821
          cellular macromolecule biosynthetic process 3148
            DNA biosynthetic process 161
              RNA-dependent DNA biosynthetic process 60
                reverse transcription + 0
                telomere maintenance via telomerase + 60
Path 2
Term Annotations click to browse term
  biological_process 12173
    metabolic process 7652
      cellular metabolic process 7017
        heterocycle metabolic process 3727
          nucleobase-containing compound metabolic process 3616
            nucleic acid metabolic process 3315
              DNA metabolic process 669
                DNA biosynthetic process 161
                  RNA-dependent DNA biosynthetic process 60
                    reverse transcription + 0
                    telomere maintenance via telomerase + 60
paths to the root