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ONTOLOGY REPORT - ANNOTATIONS


Term:RNA-dependent DNA biosynthetic process
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Accession:GO:0006278 term browser browse the term
Definition:A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand.



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RNA-dependent DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TERT telomerase reverse transcriptase involved_in ISO (PMID:9398860) BHF-UCL PMID:9398860 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951
JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in ISO (PMID:15181449)
(PMID:15380063)
BHF-UCL PMID:15181449 PMID:15380063 NCBI chr 5:81,789,915...81,792,725
Ensembl chr 5:81,789,997...81,792,639
JBrowse link
G CTC1 CST telomere replication complex component 1 involved_in ISO (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr 5:33,033,474...33,055,004
Ensembl chr 5:33,033,596...33,055,142
JBrowse link
G DCP2 decapping mRNA 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:35,256,772...35,298,974
Ensembl chr 4:35,256,970...35,299,021
JBrowse link
G EXOSC10 exosome component 10 involved_in ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 2:84,942,801...84,964,129
Ensembl chr 2:84,942,777...84,964,130
JBrowse link
G GNL3L G protein nucleolar 3 like involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr  X:46,270,162...46,296,972
Ensembl chr  X:46,189,870...46,296,966
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr27:1,013,459...1,020,083
Ensembl chr27:1,015,868...1,019,891
JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr 7:35,832,956...35,842,898
Ensembl chr 7:35,833,988...35,843,754
JBrowse link
G LOC475399 heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr15:18,239,810...18,299,065 JBrowse link
G NAT10 N-acetyltransferase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:33,654,701...33,692,642
Ensembl chr18:33,655,311...33,689,923
JBrowse link
G PIF1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:23657261) BHF-UCL PMID:23657261 NCBI chr30:29,223,507...29,232,584
Ensembl chr30:29,157,119...29,232,043
JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in ISO (PMID:21119197)
(PMID:11701125)
BHF-UCL PMID:11701125 PMID:21119197 NCBI chr25:27,090,244...27,182,377
Ensembl chr25:27,021,704...27,181,968
JBrowse link
G PML PML nuclear body scaffold involved_in ISO (PMID:19567472) UniProt PMID:19567472 NCBI chr30:37,232,337...37,278,434
Ensembl chr30:37,232,306...37,277,741
JBrowse link
G POT1 protection of telomeres 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:10,987,385...11,067,473
Ensembl chr14:10,987,494...11,066,956
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077
JBrowse link
G STN1 STN1 subunit of CST complex involved_in ISO (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr28:16,203,607...16,246,468
Ensembl chr28:16,204,073...16,246,058
JBrowse link
G TEN1 TEN1 subunit of CST complex involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:4,635,192...4,658,455
Ensembl chr 9:4,635,354...4,658,252
JBrowse link
G TENT4B terminal nucleotidyltransferase 4B involved_in ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 2:65,068,088...65,147,853
Ensembl chr 2:65,071,111...65,147,896
JBrowse link
G TERF1 telomeric repeat binding factor 1 involved_in ISO (PMID:11971978) BHF-UCL PMID:11971978 NCBI chr29:21,664,378...21,701,491
Ensembl chr29:21,664,186...21,700,495
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in ISO (PMID:17055345)
(PMID:11971978)
BHF-UCL PMID:11971978 PMID:17055345 NCBI chr 5:80,278,224...80,305,315
Ensembl chr 5:80,277,505...80,306,342
JBrowse link
G TINF2 TERF1 interacting nuclear factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:4,221,183...4,223,863
Ensembl chr 8:4,221,269...4,223,512
JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in ISO (PMID:17237768) BHF-UCL PMID:17237768 NCBI chr 5:81,789,915...81,792,725
Ensembl chr 5:81,789,997...81,792,639
JBrowse link
G ATM ATM serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:5705431 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
JBrowse link
G ATR ATR serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:5705431 NCBI chr23:38,131,956...38,223,888
Ensembl chr23:38,132,788...38,224,016
JBrowse link
G AURKB aurora kinase B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:33,014,098...33,028,951
Ensembl chr 5:33,014,102...33,033,948
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr10:11,560,287...11,586,559
Ensembl chr10:11,560,396...11,578,433
JBrowse link
G CCT3 chaperonin containing TCP1 subunit 3 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 7:41,566,274...41,583,903
Ensembl chr 7:41,566,292...41,584,863
JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:61,859,148...61,874,030
Ensembl chr10:61,859,245...61,874,389
JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr34:4,035,851...4,049,131
Ensembl chr34:4,035,857...4,049,244
JBrowse link
G CCT6A chaperonin containing TCP1 subunit 6A involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 6:546,278...556,996
Ensembl chr 6:546,307...557,001
JBrowse link
G CCT8 chaperonin containing TCP1 subunit 8 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr31:24,061,185...24,075,002
Ensembl chr31:24,061,252...24,075,364
JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of ISO (MGI:5428344|PMID:22723415) BHF-UCL PMID:22723415 MGI:5428344 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927
JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3047190|PMID:15240872) Ensembl
MGI
PMID:15240872 GO_REF:0000107 MGI:3047190 NCBI chr  X:122,838,787...122,850,870
Ensembl chr  X:122,838,645...122,850,884
JBrowse link
G FBXO4 F-box protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:67,620,947...67,664,862
Ensembl chr 4:67,651,275...67,664,915
JBrowse link
G HMBOX1 homeobox containing 1 involved_in ISO (PMID:23685356) BHF-UCL PMID:23685356 NCBI chr25:28,489,472...28,679,322
Ensembl chr25:28,489,506...28,679,748
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr27:1,013,459...1,020,083
Ensembl chr27:1,015,868...1,019,891
JBrowse link
G LOC100856782 T-complex protein 1 subunit eta involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr34:37,026,053...37,027,839 JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:52,594,450...52,604,236
Ensembl chr20:52,594,536...52,602,150
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:49,590,615...49,702,289
Ensembl chr 1:49,548,274...49,702,289
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G MAPK15 mitogen-activated protein kinase 15 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr13:37,317,061...37,322,792
Ensembl chr13:37,316,424...37,322,792
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425
JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:9,380,551...9,420,564
Ensembl chr26:9,319,180...9,419,236
JBrowse link
G NEK2 NIMA related kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:10,039,617...10,052,511
Ensembl chr 7:10,040,187...10,052,512
JBrowse link
G NEK7 NIMA related kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 7:4,557,754...4,755,912
Ensembl chr 7:4,555,231...4,704,955
JBrowse link
G PARN poly(A)-specific ribonuclease involved_in ISO (PMID:26482878), (PMID:26950371) BHF-UCL PMID:26482878 PMID:26950371 NCBI chr 6:28,629,137...28,783,671
Ensembl chr 6:28,629,174...28,783,901
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:61,960,466...62,049,553
Ensembl chr 1:61,967,129...62,088,547
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:106,695,649...106,707,229
Ensembl chr 1:106,694,589...106,702,150
JBrowse link
G POT1 protection of telomeres 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:10,987,385...11,067,473
Ensembl chr14:10,987,494...11,066,956
JBrowse link
G PRKCQ protein kinase C theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:29,319,123...29,505,338
Ensembl chr 2:29,318,870...29,505,337
JBrowse link
G TCP1 t-complex 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,029,260...49,038,023
Ensembl chr 1:49,029,282...49,038,020
JBrowse link
G TNKS tankyrase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:34,826,248...35,040,004
Ensembl chr16:34,831,662...35,039,946
JBrowse link
G XRCC5 X-ray repair cross complementing 5 involved_in ISO (PMID:19188702) BHF-UCL PMID:19188702 NCBI chr37:23,095,769...23,185,680
Ensembl chr37:23,095,754...23,185,586
JBrowse link
regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase involved_in ISO (PMID:26586433) BHF-UCL PMID:26586433 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
JBrowse link
G POT1 protection of telomeres 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:10,987,385...11,067,473
Ensembl chr14:10,987,494...11,066,956
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in ISO (PMID:19864690)
(PMID:23685356)
BHF-UCL PMID:19864690 PMID:23685356 NCBI chr 5:80,278,224...80,305,315
Ensembl chr 5:80,277,505...80,306,342
JBrowse link
telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKC1 dyskerin pseudouridine synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:122,838,787...122,850,870
Ensembl chr  X:122,838,645...122,850,884
JBrowse link
G GAR1 GAR1 ribonucleoprotein involved_in ISO (PMID:29695869) UniProt PMID:29695869 NCBI chr32:29,995,710...30,004,545
Ensembl chr32:29,996,148...30,004,536
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 involved_in ISO (PMID:10197982) BHF-UCL PMID:10197982 NCBI chr 8:70,091,203...70,096,107
Ensembl chr 8:70,092,217...70,095,243
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:12,658,415...12,664,945
Ensembl chr12:12,660,008...12,664,940
JBrowse link
G NHP2 NHP2 ribonucleoprotein involved_in ISO (PMID:29695869) UniProt PMID:29695869 NCBI chr11:3,389,549...3,393,010
Ensembl chr11:3,389,591...3,395,313
JBrowse link
G NOP10 NOP10 ribonucleoprotein involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:766,801...767,615
Ensembl chr30:766,853...767,613
JBrowse link
G PARP4 poly(ADP-ribose) polymerase family member 4 NOT|acts_upstream_of_or_within ISO (MGI:3045914|PMID:15169895) MGI PMID:15169895 MGI:3045914 NCBI chr25:18,447,413...18,544,990
Ensembl chr25:18,447,413...18,544,777
JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 acts_upstream_of_or_within ISO (PMID:11701125) MGI PMID:11701125 NCBI chr25:27,090,244...27,182,377
Ensembl chr25:27,021,704...27,181,968
JBrowse link
G POT1 protection of telomeres 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:10,987,385...11,067,473
Ensembl chr14:10,987,494...11,066,956
JBrowse link
G PTGES3 prostaglandin E synthase 3 involved_in ISO (PMID:19740745)
(MGI:5819359|PMID:10197982)
(PMID:10197982), (PMID:19740745)
BHF-UCL PMID:10197982 PMID:19740745 MGI:5819359 NCBI chr10:885,744...903,814
Ensembl chr10:870,392...909,161
JBrowse link
G RAD50 RAD50 double strand break repair protein involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:20,836,863...20,928,930
Ensembl chr11:20,836,879...20,928,819
JBrowse link
G RPA1 replication protein A1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:45,958,566...46,034,850
Ensembl chr 9:45,958,619...46,034,328
JBrowse link
G TEP1 telomerase associated protein 1 NOT|acts_upstream_of_or_within ISO (MGI:3045914|PMID:15169895) MGI PMID:15169895 MGI:3045914 NCBI chr15:17,716,887...17,748,485
Ensembl chr15:17,716,887...17,764,356
JBrowse link
G TERF1 telomeric repeat binding factor 1 involved_in ISO (PMID:9034193)
(PMID:23685356)
UniProt
BHF-UCL
PMID:9034193 PMID:23685356 NCBI chr29:21,664,378...21,701,491
Ensembl chr29:21,664,186...21,700,495
JBrowse link
G TERT telomerase reverse transcriptase involved_in ISS
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951
JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in ISO (PMID:23685356)
(PMID:23685356), (PMID:29695869), (PMID:29804836)
BHF-UCL
UniProt
PMID:23685356 PMID:29695869 PMID:29804836 NCBI chr 5:32,574,153...32,586,222
Ensembl chr 5:32,574,134...32,594,333
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13874
    metabolic process 8976
      biosynthetic process 4553
        cellular biosynthetic process 4413
          cellular macromolecule biosynthetic process 3659
            DNA biosynthetic process 166
              RNA-dependent DNA biosynthetic process 61
                reverse transcription + 0
                telomere maintenance via telomerase + 61
Path 2
Term Annotations click to browse term
  biological_process 13874
    metabolic process 8976
      cellular metabolic process 8165
        heterocycle metabolic process 4313
          nucleobase-containing compound metabolic process 4193
            nucleic acid metabolic process 3832
              DNA metabolic process 737
                DNA biosynthetic process 166
                  RNA-dependent DNA biosynthetic process 61
                    reverse transcription + 0
                    telomere maintenance via telomerase + 61
paths to the root