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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA unwinding involved in DNA replication
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Accession:GO:0006268 term browser browse the term
Definition:The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
Comment:Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'.
Synonyms:related_synonym: DNA unwinding during replication;   DNA unwinding factor



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DNA unwinding involved in DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2156014|PMID:10531422)
RGD PMID:10531422 PMID:21873635 MGI:2156014, RGD:13792537 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
PR:P97311|PR:Q61881 (MGI:3582148|PMID:15917436)
RGD PMID:15917436 PMID:21873635 MGI:3582148, RGD:13792537 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
PR:P49717|PR:Q61881 (MGI:3582148|PMID:15917436)
PMID:21873635
Ensembl
RGD
PMID:15917436 PMID:21873635 GO_REF:0000107 MGI:3582148, RGD:13792537 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
PR:P49717|PR:P97311 (MGI:3582148|PMID:15917436)
RGD PMID:15917436 PMID:21873635 MGI:3582148, RGD:13792537 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
JBrowse link
G Pura purine rich element binding protein A involved_in IEA
ISO
GO_REF:0000107
(PMID:15777841)
Ensembl
RGD
PMID:15777841 GO_REF:0000107
G Rad51 RAD51 recombinase involved_in ISO (PMID:7988572) RGD PMID:7988572 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Recql RecQ like helicase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945
JBrowse link
G Recql4 RecQ like helicase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619
JBrowse link
G Recql5 RecQ like helicase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652
JBrowse link
G Rpa1 replication protein A1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:60,148,869...60,199,999
Ensembl chr10:60,148,793...60,199,949
JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in ISO
IEA
(PMID:26446790)
GO_REF:0000107
RGD
Ensembl
PMID:26446790 GO_REF:0000107 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135
JBrowse link
G Twnk twinkle mtDNA helicase involved_in
acts_upstream_of_or_within
ISO (PMID:15167897)
(MGI:2136707|PMID:11431692)
RGD PMID:11431692 PMID:15167897 MGI:2136707 NCBI chr 1:243,867,568...243,874,802
Ensembl chr 1:243,868,330...243,874,802
JBrowse link
G Wrn WRN RecQ like helicase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      cellular metabolic process 10656
        cellular biosynthetic process 5862
          cellular macromolecule biosynthetic process 4937
            DNA replication 253
              DNA-dependent DNA replication 150
                DNA unwinding involved in DNA replication 14
                  cell cycle DNA replication DNA unwinding + 0
Path 2
Term Annotations click to browse term
  biological_process 19390
    cellular process 18252
      cellular component organization or biogenesis 6492
        cellular component organization 6250
          organelle organization 3788
            chromosome organization 900
              DNA conformation change 266
                DNA geometric change 84
                  DNA duplex unwinding 78
                    DNA unwinding involved in DNA replication 14
                      cell cycle DNA replication DNA unwinding + 0
paths to the root