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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA unwinding involved in DNA replication
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Accession:GO:0006268 term browser browse the term
Definition:The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
Comment:Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'.
Synonyms:related_synonym: DNA unwinding during replication;   DNA unwinding factor


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DNA unwinding involved in DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Cdc45 cell division cycle 45 involved_in ISO (PMID:22474384) RGD PMID:22474384 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619 		JBrowse link
G Gins1 GINS complex subunit 1 involved_in ISO (PMID:22474384) RGD PMID:22474384 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936 		JBrowse link
G Gins2 GINS complex subunit 2 involved_in ISO (PMID:22474384) RGD PMID:22474384 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339 		JBrowse link
G Gins3 GINS complex subunit 3 involved_in ISO (PMID:22474384) RGD PMID:22474384 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687 		JBrowse link
G Gins4 GINS complex subunit 4 involved_in ISO
IEA		 (PMID:22474384)
GO_REF:0000107		 RGD
Ensembl		 PMID:22474384 GO_REF:0000107 NCBI chr16:68,787,572...68,799,938
Ensembl chr16:68,767,339...68,802,273 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2156014|PMID:10531422)
PMID:21873635
(PMID:22474384)		 RGD PMID:10531422 PMID:22474384 PMID:21873635 MGI:2156014, RGD:13792537 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 involved_in ISO (PMID:22474384) RGD PMID:22474384 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314 		JBrowse link
G Mcm4 minichromosome maintenance complex component 4 acts_upstream_of_or_within
involved_in		 ISO
IBA		 PR:P97311|PR:Q61881 (MGI:3582148|PMID:15917436)
PMID:21873635
(PMID:22474384)		 RGD PMID:15917436 PMID:22474384 PMID:21873635 MGI:3582148, RGD:13792537 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 involved_in ISO (PMID:22474384) RGD PMID:22474384 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:22474384)
PR:P49717|PR:Q61881 (MGI:3582148|PMID:15917436)		 Ensembl
RGD		 PMID:15917436 PMID:22474384 GO_REF:0000107 MGI:3582148 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960 		JBrowse link
G Mcm7 minichromosome maintenance complex component 7 acts_upstream_of_or_within
involved_in		 ISO
IBA		 PR:P49717|PR:P97311 (MGI:3582148|PMID:15917436)
PMID:21873635
(PMID:22474384)		 RGD PMID:15917436 PMID:22474384 PMID:21873635 MGI:3582148, RGD:13792537 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063 		JBrowse link
G Pura purine rich element binding protein A involved_in ISO (PMID:15777841) RGD PMID:15777841 NCBI chr18:27,884,618...27,905,500
Ensembl chr18:27,884,556...27,905,513 		JBrowse link
G Rad51 RAD51 recombinase involved_in ISO (PMID:7988572) RGD PMID:7988572 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Recql RecQ like helicase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945 		JBrowse link
G Recql4 RecQ like helicase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619 		JBrowse link
G Recql5 RecQ like helicase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in ISO (PMID:26446790) RGD PMID:26446790 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135 		JBrowse link
G Twnk twinkle mtDNA helicase involved_in
acts_upstream_of_or_within		 ISO (PMID:15167897)
(MGI:2136707|PMID:11431692)		 RGD PMID:11431692 PMID:15167897 MGI:2136707 NCBI chr 1:243,867,568...243,874,802
Ensembl chr 1:243,868,330...243,874,802 		JBrowse link
G Wrn WRN RecQ like helicase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      primary metabolic process 8886
        nucleobase-containing compound metabolic process 2783
          nucleic acid metabolic process 2274
            DNA metabolic process 1001
              DNA replication 274
                DNA-templated DNA replication 156
                  DNA unwinding involved in DNA replication 20
                    cell cycle DNA replication DNA unwinding + 0
Path 2
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      cellular metabolic process 7444
        cellular aromatic compound metabolic process 3032
          nucleobase-containing compound metabolic process 2783
            nucleic acid metabolic process 2274
              DNA metabolic process 1001
                DNA replication 274
                  DNA-templated DNA replication 156
                    DNA unwinding involved in DNA replication 20
                      cell cycle DNA replication DNA unwinding + 0
paths to the root