This term is obsolete.
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Definition:
OBSOLETE. The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
Comment:
Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'.\nThe reason for obsoletion is that the term represents a molecular function.
Synonyms:
related_synonym:
DNA unwinding during replication; DNA unwinding factor