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ONTOLOGY REPORT - ANNOTATIONS

Term:mitochondrial DNA replication
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Accession:GO:0006264 term browser browse the term
Definition:The process in which new strands of DNA are synthesized in the mitochondrion.
Synonyms:exact_synonym: mtDNA replication;   replication of mitochondrial DNA
 related_synonym: mitochondrial DNA synthesis;   mtDNA synthesis
 only_in_taxon: NCBITaxon:2759 ! Eukaryota


show annotations for term's descendants           Sort by:
mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dna2 DNA replication helicase/nuclease 2 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:25,661,652...25,690,598
Ensembl chr20:25,662,055...25,716,319 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 acts_upstream_of_or_within ISO MGI:2182091|MGI:3040717 (PMID:16327803) RGD PMID:16327803 NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161 		JBrowse link
G Mgme1 mitochondrial genome maintenance exonuclease 1 involved_in ISO
IBA		 (PMID:23313956)
GO_REF:0000033		 RGD
GO_Central		 PMID:23313956 GO_REF:0000033 NCBI chr 3:131,640,770...131,649,933
Ensembl chr 3:131,640,944...131,649,932 		JBrowse link
G Polg DNA polymerase gamma, catalytic subunit involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:19837034), (PMID:26554610)
(PMID:26095671)
MGI:3584444 (PMID:15888483)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:15888483 PMID:19837034 PMID:26095671 PMID:26554610 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567 		JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:19837034)
MGI:5470227 (PMID:23197651)
GO_REF:0000033		 RGD
GO_Central		 PMID:19837034 PMID:23197651 GO_REF:0000033 NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008 		JBrowse link
G Primpol primase and DNA directed polymerase involved_in ISO
IBA		 (PMID:24207056)
GO_REF:0000033		 RGD
GO_Central		 PMID:24207056 GO_REF:0000033 NCBI chr16:45,681,252...45,715,758
Ensembl chr16:45,681,326...45,715,565 		JBrowse link
G Rnaseh1 ribonuclease H1 acts_upstream_of_or_within ISO MGI:2655784 (PMID:12667461) RGD PMID:12667461 NCBI chr 6:45,282,849...45,292,258
Ensembl chr 6:45,282,854...45,292,236 		JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 involved_in ISO (PMID:17486094) RGD PMID:17486094 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261 		JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B involved_in
acts_upstream_of_or_within		 ISO (PMID:17486094)
MGI:2672883 (PMID:17486094)		 RGD PMID:17486094 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135 		JBrowse link
G Tefm transcription elongation factor, mitochondrial NOT|involved_in ISO (PMID:21278163) RGD PMID:21278163 NCBI chr10:65,119,657...65,124,233
Ensembl chr10:65,119,659...65,124,486 		JBrowse link
G Tk2 thymidine kinase 2 acts_upstream_of_or_within ISO MGI:3802583 (PMID:18434326) RGD PMID:18434326 NCBI chr19:708,859...731,786
Ensembl chr19:708,891...730,924 		JBrowse link
G Twnk twinkle mtDNA helicase involved_in ISO
IBA		 (PMID:18971204)
GO_REF:0000033		 RGD
GO_Central		 PMID:18971204 GO_REF:0000033 NCBI chr 1:243,867,568...243,874,802
Ensembl chr 1:243,868,330...243,874,802 		JBrowse link
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 IMP RGD PMID:23800874 RGD:11557986 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Lig3 DNA ligase 3 involved_in ISO (PMID:21878356) RGD PMID:21878356 NCBI chr10:67,717,808...67,741,141
Ensembl chr10:67,717,812...67,798,414 		JBrowse link
positive regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Endog endonuclease G involved_in ISO (PMID:29719607) RGD PMID:29719607 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932 		JBrowse link
G Mtnap1 mitochondrial nucleoid associated protein 1 involved_in ISO (PMID:37676315) RGD PMID:37676315 NCBI chr10:98,728,661...98,738,693
Ensembl chr10:98,727,763...98,738,691 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in ISO
IEA
ISS		 (PMID:31550240)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:31550240 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135 		JBrowse link
regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl4 methyltransferase 4, N6-adenosine involved_in ISO (PMID:32183942) RGD PMID:32183942 NCBI chr 9:111,440,976...111,523,871
Ensembl chr 9:111,441,027...111,464,749 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        macromolecule metabolic process 9812
          nucleic acid metabolic process 5186
            DNA metabolic process 967
              mitochondrial DNA metabolic process 27
                mitochondrial DNA replication 18
                  DNA synthesis involved in mitochondrial DNA replication 0
                  kinetoplast DNA replication 0
                  negative regulation of mitochondrial DNA replication 2
                  positive regulation of mitochondrial DNA replication 3
                  regulation of mitochondrial DNA replication + 6
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        primary metabolic process 10582
          nucleobase-containing compound metabolic process 5795
            nucleic acid metabolic process 5186
              DNA metabolic process 967
                DNA replication 271
                  DNA-templated DNA replication 160
                    mitochondrial DNA replication 18
                      DNA synthesis involved in mitochondrial DNA replication 0
                      kinetoplast DNA replication 0
                      negative regulation of mitochondrial DNA replication 2
                      positive regulation of mitochondrial DNA replication 3
                      regulation of mitochondrial DNA replication + 6
paths to the root