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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA-templated DNA replication
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Accession:GO:0006261 term browser browse the term
Definition:A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.
Synonyms:exact_synonym: DNA-dependent DNA replication
 alt_id: GO:0006262;   GO:0006263
 xref: Reactome:R-HSA-69306 "DNA Replication"


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DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baz1a bromodomain adjacent to zinc finger domain 1A involved_in ISO (PMID:12434153) UniProt PMID:12434153 NCBI chrNW_004955409:26,136,961...26,231,960
Ensembl chrNW_004955409:26,149,665...26,231,180
JBrowse link
G Helb DNA helicase B acts_upstream_of_or_within ISO (PMID:11557815) MGI PMID:11557815 NCBI chrNW_004955458:12,929,345...12,971,059
Ensembl chrNW_004955458:12,929,447...12,974,154
JBrowse link
G Mcmbp minichromosome maintenance complex binding protein involved_in ISO (PMID:21196493) UniProt PMID:21196493 NCBI chrNW_004955551:643,760...688,299
Ensembl chrNW_004955551:643,760...688,299
JBrowse link
G Orc6 origin recognition complex subunit 6 acts_upstream_of_or_within ISO (PMID:20219456) MGI PMID:20219456 NCBI chrNW_004955448:240,518...248,379
Ensembl chrNW_004955448:240,697...247,986
JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit involved_in ISO (PMID:20334433) RGD
ComplexPortal
PMID:7503737 PMID:9620226 PMID:20334433 RGD:2299945 RGD:2307013 NCBI chrNW_004955559:712,375...730,551
Ensembl chrNW_004955559:712,321...725,661
JBrowse link
G Pold2 DNA polymerase delta 2, accessory subunit involved_in ISO (PMID:20334433) RGD
ComplexPortal
PMID:7503737 PMID:20334433 RGD:2307013 NCBI chrNW_004955456:7,853,476...7,860,108
Ensembl chrNW_004955456:7,853,476...7,860,108
JBrowse link
G Pold3 DNA polymerase delta 3, accessory subunit involved_in ISO (PMID:20334433) RGD
ComplexPortal
PMID:7503737 PMID:20334433 RGD:2307013 NCBI chrNW_004955414:17,064,379...17,111,946 JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit involved_in ISO (PMID:20334433) RGD
ComplexPortal
PMID:7503737 PMID:20334433 RGD:2307013 NCBI chrNW_004955422:18,116,604...18,118,280
Ensembl chrNW_004955422:18,116,610...18,118,280
JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit involved_in ISO (PMID:33051204) ComplexPortal PMID:33051204 NCBI chrNW_004955482:373,467...418,000
Ensembl chrNW_004955482:373,555...417,266
JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit involved_in ISO (PMID:33051204) ComplexPortal PMID:33051204 NCBI chrNW_004955409:12,983,488...13,014,669
Ensembl chrNW_004955409:12,983,586...13,014,578
JBrowse link
G Pole3 DNA polymerase epsilon 3, accessory subunit involved_in ISO (PMID:33051204) ComplexPortal PMID:33051204 NCBI chrNW_004955419:14,086,940...14,089,906
Ensembl chrNW_004955419:14,086,940...14,089,330
JBrowse link
G Pole4 DNA polymerase epsilon 4, accessory subunit involved_in ISO (PMID:33051204) ComplexPortal PMID:33051204 NCBI chrNW_004955424:10,839,639...10,844,985
Ensembl chrNW_004955424:10,839,639...10,844,985
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit involved_in ISO (PMID:10608893), (PMID:15167897), (PMID:19837034), (PMID:19858216), (PMID:26123486), (PMID:26446790), (PMID:28430993) UniProt PMID:10608893 PMID:15167897 PMID:19837034 PMID:19858216 PMID:26123486 More... NCBI chrNW_004955416:15,773,005...15,788,736
Ensembl chrNW_004955416:15,773,473...15,788,651
JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit involved_in ISO (PMID:10608893), (PMID:15167897), (PMID:19837034), (PMID:19858216), (PMID:26123486), (PMID:26446790), (PMID:28430993) FlyBase PMID:10608893 PMID:15167897 PMID:19837034 PMID:19858216 PMID:26123486 More... NCBI chrNW_004955478:7,376,240...7,396,647
Ensembl chrNW_004955478:7,376,712...7,396,647
JBrowse link
G Rfc1 replication factor C subunit 1 involved_in ISO (PMID:9488738) ComplexPortal PMID:9488738 NCBI chrNW_004955443:7,969,117...8,051,734
Ensembl chrNW_004955443:7,983,840...8,051,089
JBrowse link
G Rfc2 replication factor C subunit 2 involved_in ISO (PMID:9488738) ComplexPortal PMID:9488738 NCBI chrNW_004955456:13,659,122...13,671,405
Ensembl chrNW_004955456:13,659,157...13,671,181
JBrowse link
G Rfc3 replication factor C subunit 3 involved_in ISO (PMID:9488738) ComplexPortal PMID:9488738 NCBI chrNW_004955431:12,071,465...12,084,570
Ensembl chrNW_004955431:12,069,204...12,084,577
JBrowse link
G Rfc4 replication factor C subunit 4 involved_in ISO (PMID:9488738) ComplexPortal PMID:9488738 NCBI chrNW_004955420:20,948,549...20,967,845
Ensembl chrNW_004955420:20,948,549...20,967,845
JBrowse link
G Rfc5 replication factor C subunit 5 involved_in ISO (PMID:9488738) ComplexPortal PMID:9488738 NCBI chrNW_004955455:13,325,912...13,337,241
Ensembl chrNW_004955455:13,326,271...13,338,050
JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in ISO (PMID:26446790) FlyBase PMID:26446790 NCBI chrNW_004955494:1,807,885...1,826,375
Ensembl chrNW_004955494:1,814,106...1,826,375
JBrowse link
G Twnk twinkle mtDNA helicase involved_in ISO (PMID:15167897) FlyBase PMID:15167897 NCBI chrNW_004955485:9,193,838...9,198,697
Ensembl chrNW_004955485:9,191,919...9,198,697
JBrowse link
DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zpr1 ZPR1 zinc finger involved_in ISO (PMID:15767679) UniProt PMID:15767679 NCBI chrNW_004955412:18,117,957...18,127,552
Ensembl chrNW_004955412:18,116,531...18,127,552
JBrowse link
DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccne1 cyclin E1 acts_upstream_of_or_within ISO (PMID:12941272) MGI PMID:12941272 NCBI chrNW_004955468:7,803,610...7,814,872
Ensembl chrNW_004955468:7,803,346...7,814,872
JBrowse link
G Ccne2 cyclin E2 acts_upstream_of_or_within ISO (PMID:12941272) MGI PMID:12941272 NCBI chrNW_004955417:11,027,749...11,039,945
Ensembl chrNW_004955417:11,027,749...11,040,017
JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor involved_in ISO (PMID:32865517) UniProt PMID:32865517 NCBI chrNW_004955462:1,151,163...1,186,601
Ensembl chrNW_004955462:1,153,058...1,188,799
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 involved_in ISO (PMID:16899510) UniProt PMID:16899510 NCBI chrNW_004955429:16,012,345...16,027,151
Ensembl chrNW_004955429:16,012,173...16,027,277
JBrowse link
G Orc1 origin recognition complex subunit 1 involved_in ISO (PMID:16549788) ComplexPortal PMID:16549788 NCBI chrNW_004955464:6,761,046...6,787,144
Ensembl chrNW_004955464:6,764,992...6,787,066
JBrowse link
G Orc2 origin recognition complex subunit 2 involved_in ISO (PMID:16549788) ComplexPortal PMID:16549788 NCBI chrNW_004955403:576,268...628,068
Ensembl chrNW_004955403:577,955...628,068
JBrowse link
G Orc3 origin recognition complex subunit 3 involved_in ISO (PMID:16549788) ComplexPortal PMID:16549788 NCBI chrNW_004955411:14,527,987...14,595,216
Ensembl chrNW_004955411:14,528,043...14,595,616
JBrowse link
G Orc4 origin recognition complex subunit 4 involved_in ISO (PMID:9353276)
(PMID:16549788)
UniProt
ComplexPortal
PMID:9353276 PMID:16549788 NCBI chrNW_004955440:13,933,896...14,006,808
Ensembl chrNW_004955440:13,932,495...14,006,806
JBrowse link
G Orc5 origin recognition complex subunit 5 involved_in ISO (PMID:16549788) ComplexPortal PMID:16549788 NCBI chrNW_004955410:8,969,353...9,024,525
Ensembl chrNW_004955410:8,969,290...9,024,542
JBrowse link
G Orc6 origin recognition complex subunit 6 involved_in ISO (PMID:16549788) ComplexPortal PMID:16549788 NCBI chrNW_004955448:240,518...248,379
Ensembl chrNW_004955448:240,697...247,986
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit involved_in ISO (PMID:10523676)
(PMID:2175912), (PMID:26975377)
ComplexPortal PMID:2175912 PMID:10523676 PMID:26975377 NCBI chrNW_004955509:5,007,385...5,319,683
Ensembl chrNW_004955509:5,007,182...5,319,894
JBrowse link
G Pola2 DNA polymerase alpha 2, accessory subunit involved_in ISO (PMID:26975377)
(PMID:10523676)
ComplexPortal PMID:10523676 PMID:26975377 NCBI chrNW_004955422:19,939,971...19,963,753
Ensembl chrNW_004955422:19,939,933...19,963,753
JBrowse link
G Prim1 DNA primase subunit 1 involved_in ISO (PMID:26975377)
(PMID:10523676)
ComplexPortal PMID:10523676 PMID:26975377 NCBI chrNW_004955458:4,265,500...4,294,329
Ensembl chrNW_004955458:4,275,517...4,294,257
JBrowse link
G Prim2 DNA primase subunit 2 involved_in ISO (PMID:10523676)
(PMID:26975377)
ComplexPortal PMID:10523676 PMID:26975377 NCBI chrNW_004955502:2,642,328...2,898,919
Ensembl chrNW_004955502:2,647,462...2,898,919
JBrowse link
DNA replication preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:11125146) CAFA PMID:11125146 NCBI chrNW_004955541:2,683,030...2,687,883
Ensembl chrNW_004955541:2,683,408...2,687,102
JBrowse link
G Gmnn geminin DNA replication inhibitor involved_in ISO (PMID:11125146) CAFA PMID:11125146 NCBI chrNW_004955483:2,283,518...2,344,982
Ensembl chrNW_004955483:2,282,485...2,293,924
JBrowse link
DNA replication proofreading term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pold1 DNA polymerase delta 1, catalytic subunit acts_upstream_of_or_within ISO (PMID:12429860) MGI PMID:12429860 NCBI chrNW_004955559:712,375...730,551
Ensembl chrNW_004955559:712,321...725,661
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit involved_in ISO (PMID:11897778)
(PMID:37202477)
UniProt PMID:11897778 PMID:37202477 NCBI chrNW_004955416:15,773,005...15,788,736
Ensembl chrNW_004955416:15,773,473...15,788,651
JBrowse link
DNA replication, Okazaki fragment processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dna2 DNA replication helicase/nuclease 2 involved_in ISO (PMID:22570407) UniProt PMID:22570407 NCBI chrNW_004955425:20,664,412...20,705,070
Ensembl chrNW_004955425:20,661,727...20,702,754
JBrowse link
DNA replication, synthesis of primer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Helb DNA helicase B involved_in ISO (PMID:12181327) UniProt PMID:12181327 NCBI chrNW_004955458:12,929,345...12,971,059
Ensembl chrNW_004955458:12,929,447...12,974,154
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit involved_in ISO (PMID:2175912), (PMID:27019227), (PMID:8026492)
(PMID:8026492)
UniProt PMID:2175912 PMID:8026492 PMID:27019227 NCBI chrNW_004955509:5,007,385...5,319,683
Ensembl chrNW_004955509:5,007,182...5,319,894
JBrowse link
G Pola2 DNA polymerase alpha 2, accessory subunit involved_in ISO (PMID:8026492) UniProt PMID:8026492 NCBI chrNW_004955422:19,939,971...19,963,753
Ensembl chrNW_004955422:19,939,933...19,963,753
JBrowse link
G Prim1 DNA primase subunit 1 involved_in ISO (PMID:26975377), (PMID:8026492)
(PMID:8026492)
UniProt PMID:8026492 PMID:26975377 NCBI chrNW_004955458:4,265,500...4,294,329
Ensembl chrNW_004955458:4,275,517...4,294,257
JBrowse link
G Prim2 DNA primase subunit 2 involved_in ISO (PMID:8026492) UniProt PMID:8026492 NCBI chrNW_004955502:2,642,328...2,898,919
Ensembl chrNW_004955502:2,647,462...2,898,919
JBrowse link
DNA strand elongation involved in DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pola1 DNA polymerase alpha 1, catalytic subunit involved_in ISO (PMID:4084590) UniProt PMID:4084590 NCBI chrNW_004955509:5,007,385...5,319,683
Ensembl chrNW_004955509:5,007,182...5,319,894
JBrowse link
DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exo1 exonuclease 1 involved_in ISO (PMID:26240375) UniProt PMID:26240375 NCBI chrNW_004955406:10,248,981...10,276,207
Ensembl chrNW_004955406:10,245,886...10,275,522
JBrowse link
G Nbn nibrin involved_in ISO (PMID:27814491), (PMID:27889449), (PMID:30787182) UniProt PMID:27814491 PMID:27889449 PMID:30787182 NCBI chrNW_004955417:6,840,916...6,880,479
Ensembl chrNW_004955417:6,839,312...6,880,133
JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in ISO (PMID:27889449) UniProt PMID:27889449 NCBI chrNW_004955408:3,953,801...4,035,494
Ensembl chrNW_004955408:3,953,800...4,035,494
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease involved_in ISO (PMID:23273981), (PMID:27814491), (PMID:27889449), (PMID:30787182) UniProt PMID:23273981 PMID:27814491 PMID:27889449 PMID:30787182 NCBI chrNW_004955402:11,245,857...11,331,872
Ensembl chrNW_004955402:11,245,819...11,335,367
JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:28834754), (PMID:29670289) UniProt PMID:28834754 PMID:29670289 NCBI chrNW_004955422:24,714,103...24,780,672
Ensembl chrNW_004955422:24,735,161...24,778,830
JBrowse link
DNA synthesis involved in mitotic DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk2 cyclin dependent kinase 2 ISO RGD PMID:15696186 RGD:2301349 NCBI chrNW_004955458:3,555,603...3,561,063
Ensembl chrNW_004955458:3,555,603...3,562,120
JBrowse link
G Tk1 thymidine kinase 1 involved_in ISO (PMID:14697231) UniProt PMID:14697231 NCBI chrNW_004955506:4,379,830...4,390,729
Ensembl chrNW_004955506:4,379,830...4,394,713
JBrowse link
lagging strand elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pola1 DNA polymerase alpha 1, catalytic subunit involved_in ISO (PMID:2175912), (PMID:7910375) UniProt PMID:2175912 PMID:7910375 NCBI chrNW_004955509:5,007,385...5,319,683
Ensembl chrNW_004955509:5,007,182...5,319,894
JBrowse link
leading strand elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pola1 DNA polymerase alpha 1, catalytic subunit involved_in ISO (PMID:2175912), (PMID:7910375) UniProt PMID:2175912 PMID:7910375 NCBI chrNW_004955509:5,007,385...5,319,683
Ensembl chrNW_004955509:5,007,182...5,319,894
JBrowse link
mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mcm9 minichromosome maintenance 9 homologous recombination repair factor involved_in ISO (PMID:26300262) UniProt PMID:26300262 NCBI chrNW_004955436:1,642,337...1,661,362 JBrowse link
mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dna2 DNA replication helicase/nuclease 2 involved_in ISO (PMID:18995831), (PMID:19487465) UniProt PMID:18995831 PMID:19487465 NCBI chrNW_004955425:20,664,412...20,705,070
Ensembl chrNW_004955425:20,661,727...20,702,754
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 acts_upstream_of_or_within ISO (PMID:16327803) MGI PMID:16327803 NCBI chrNW_004955442:12,971,031...13,002,605
Ensembl chrNW_004955442:12,967,438...13,010,943
JBrowse link
G Mgme1 mitochondrial genome maintenance exonuclease 1 involved_in ISO (PMID:23313956) UniProt PMID:23313956 NCBI chrNW_004955415:26,805,883...26,814,485
Ensembl chrNW_004955415:26,805,396...26,828,702
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit involved_in
acts_upstream_of_or_within
ISO (PMID:19837034)
(PMID:15888483)
(PMID:26095671)
(PMID:26554610)
ComplexPortal
MGI
UniProt
PMID:15888483 PMID:19837034 PMID:26095671 PMID:26554610 NCBI chrNW_004955416:15,773,005...15,788,736
Ensembl chrNW_004955416:15,773,473...15,788,651
JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit involved_in
acts_upstream_of_or_within
ISO (PMID:19837034)
(PMID:23197651)
ComplexPortal
MGI
PMID:19837034 PMID:23197651 NCBI chrNW_004955478:7,376,240...7,396,647
Ensembl chrNW_004955478:7,376,712...7,396,647
JBrowse link
G Primpol primase and DNA directed polymerase involved_in ISO (PMID:24207056) UniProt PMID:24207056 NCBI chrNW_004955403:24,278,727...24,307,312
Ensembl chrNW_004955403:24,279,122...24,303,682
JBrowse link
G Rnaseh1 ribonuclease H1 acts_upstream_of_or_within ISO (PMID:12667461) MGI PMID:12667461 NCBI chrNW_004955487:3,808,426...3,815,682
Ensembl chrNW_004955487:3,808,419...3,815,682
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 involved_in ISO (PMID:17486094) ComplexPortal PMID:17486094 NCBI chrNW_004955414:19,850,523...19,904,879
Ensembl chrNW_004955414:19,850,530...19,905,266
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B involved_in
acts_upstream_of_or_within
ISO (PMID:17486094) ComplexPortal
MGI
PMID:17486094 NCBI chrNW_004955417:26,949,686...26,976,976
Ensembl chrNW_004955417:26,949,686...26,976,726
JBrowse link
G Tefm transcription elongation factor, mitochondrial NOT|involved_in ISO (PMID:21278163) UniProt PMID:21278163 NCBI chrNW_004955481:7,034,564...7,042,653
Ensembl chrNW_004955481:7,034,543...7,042,384
JBrowse link
G Tk2 thymidine kinase 2 acts_upstream_of_or_within ISO (PMID:18434326) MGI PMID:18434326 NCBI chrNW_004955433:23,075,930...23,106,281
Ensembl chrNW_004955433:23,075,879...23,106,288
JBrowse link
G Twnk twinkle mtDNA helicase involved_in ISO (PMID:18971204) UniProt PMID:18971204 NCBI chrNW_004955485:9,193,838...9,198,697
Ensembl chrNW_004955485:9,191,919...9,198,697
JBrowse link
mitotic DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Recql5 RecQ like helicase 5 involved_in ISO (PMID:28575661) UniProt PMID:28575661 NCBI chrNW_004955506:6,574,802...6,612,763
Ensembl chrNW_004955506:6,575,408...6,612,186
JBrowse link
mitotic recombination-dependent replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2 DNA repair associated involved_in ISO (PMID:21076401) BHF-UCL PMID:21076401 NCBI chrNW_004955431:13,449,287...13,526,878
Ensembl chrNW_004955431:13,449,543...13,527,432
JBrowse link
mitotic telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dna2 DNA replication helicase/nuclease 2 involved_in ISO (PMID:23604072) BHF-UCL PMID:23604072 NCBI chrNW_004955425:20,664,412...20,705,070
Ensembl chrNW_004955425:20,661,727...20,702,754
JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO (PMID:24115439) BHF-UCL PMID:24115439 NCBI chrNW_004955415:15,744,601...15,748,910
Ensembl chrNW_004955415:15,744,601...15,749,673
JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (PMID:24115439) BHF-UCL PMID:24115439 NCBI chrNW_004955528:531,680...578,003
Ensembl chrNW_004955528:532,385...572,398
JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:17875940) UniProt PMID:17875940 NCBI chrNW_004955439:8,830,658...8,843,653
Ensembl chrNW_004955439:8,830,975...8,843,828
JBrowse link
negative regulation of DNA strand resection involved in replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dynll1 dynein light chain LC8-type 1 involved_in ISO (PMID:30464262), (PMID:37696958) UniProt PMID:30464262 PMID:37696958 NCBI chrNW_004955455:11,148,041...11,150,860
Ensembl chrNW_004955455:11,148,047...11,150,859
JBrowse link
negative regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:19906994) ComplexPortal PMID:19906994 NCBI chrNW_004955541:2,683,030...2,687,883
Ensembl chrNW_004955541:2,683,408...2,687,102
JBrowse link
G Gmnn geminin DNA replication inhibitor involved_in ISO (PMID:11125146), (PMID:19906994) CAFA PMID:11125146 PMID:19906994 NCBI chrNW_004955483:2,283,518...2,344,982
Ensembl chrNW_004955483:2,282,485...2,293,924
JBrowse link
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 ISO RGD PMID:23800874 RGD:11557986 NCBI chrNW_004955429:14,076,976...14,301,034
Ensembl chrNW_004955429:14,076,960...14,304,236
JBrowse link
G Lig3 DNA ligase 3 involved_in ISO (PMID:21878356) CACAO PMID:21878356 NCBI chrNW_004955481:9,696,050...9,716,154
Ensembl chrNW_004955481:9,696,054...9,715,637
JBrowse link
nuclear DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 involved_in ISO (PMID:25404367) MGI PMID:25404367 NCBI chrNW_004955481:6,986,128...7,031,113
Ensembl chrNW_004955481:6,986,502...7,030,742
JBrowse link
G Rpa4 replication protein A4 NOT|involved_in ISO (PMID:19116208), (PMID:19942684) UniProt PMID:19116208 PMID:19942684 NCBI chrNW_004955503:2,514,460...2,516,973 JBrowse link
G Znf830 zinc finger protein 830 acts_upstream_of_or_within ISO (PMID:21191184) MGI PMID:21191184 NCBI chrNW_004955481:9,661,791...9,663,326
Ensembl chrNW_004955481:9,661,830...9,662,918
JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2f7 E2F transcription factor 7 involved_in ISO (PMID:23064266) UniProt PMID:23064266 NCBI chrNW_004955405:16,148,640...16,187,272
Ensembl chrNW_004955405:16,148,480...16,186,282
JBrowse link
G E2f8 E2F transcription factor 8 involved_in ISO (PMID:23064264), (PMID:23064266) UniProt PMID:23064264 PMID:23064266 NCBI chrNW_004955476:197,699...215,227
Ensembl chrNW_004955476:197,630...213,441
JBrowse link
positive regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor involved_in ISO (PMID:36807739) UniProt PMID:36807739 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:11125146) CAFA PMID:11125146 NCBI chrNW_004955541:2,683,030...2,687,883
Ensembl chrNW_004955541:2,683,408...2,687,102
JBrowse link
positive regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk2 cyclin dependent kinase 2 acts_upstream_of_or_within ISO (PMID:20215406) MGI PMID:20215406 NCBI chrNW_004955458:3,555,603...3,561,063
Ensembl chrNW_004955458:3,555,603...3,562,120
JBrowse link
G Ciz1 CDKN1A interacting zinc finger protein 1 acts_upstream_of_or_within ISO (PMID:15585571)
(PMID:20215406)
MGI PMID:15585571 PMID:20215406 NCBI chrNW_004955570:716,124...732,551
Ensembl chrNW_004955570:707,637...732,980
JBrowse link
positive regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Endog endonuclease G involved_in ISO (PMID:29719607) UniProt PMID:29719607 NCBI chrNW_004955570:1,200,461...1,203,566
Ensembl chrNW_004955570:1,200,996...1,203,566
JBrowse link
G Mtnap1 mitochondrial nucleoid associated protein 1 involved_in ISO (PMID:37676315) UniProt PMID:37676315 NCBI chrNW_004955553:251,370...328,606
Ensembl chrNW_004955553:252,095...362,568
JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in ISO (PMID:31550240) UniProt PMID:31550240 NCBI chrNW_004955494:1,807,885...1,826,375
Ensembl chrNW_004955494:1,814,106...1,826,375
JBrowse link
positive regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (PMID:2161540) MGI PMID:2161540 NCBI chrNW_004955463:14,013,247...14,064,354
Ensembl chrNW_004955463:14,013,247...14,064,111
JBrowse link
positive regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX chromatin remodeler involved_in ISO (PMID:24651726) UniProt PMID:24651726 NCBI chrNW_004955557:947,368...1,252,701
Ensembl chrNW_004955557:947,167...1,252,724
JBrowse link
G Cdc7 cell division cycle 7 involved_in ISO (PMID:15668232) UniProt PMID:15668232 NCBI chrNW_004955423:2,902,352...2,923,743
Ensembl chrNW_004955423:2,902,048...2,924,573
JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (PMID:20237820) UniProt PMID:20237820 NCBI chrNW_004955416:7,870,521...8,020,862
Ensembl chrNW_004955416:7,870,258...7,961,812
JBrowse link
G Wiz WIZ zinc finger involved_in ISO (PMID:23545495) UniProt PMID:23545495 NCBI chrNW_004955495:7,810,145...7,834,908
Ensembl chrNW_004955495:7,811,804...7,833,918
JBrowse link
regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Senp2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO (PMID:19090619) MGI PMID:19090619 NCBI chrNW_004955420:21,969,537...22,005,094
Ensembl chrNW_004955420:21,969,537...22,005,856
JBrowse link
regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:11125146)
(PMID:12192004)
UniProt PMID:11125146 PMID:12192004 NCBI chrNW_004955541:2,683,030...2,687,883
Ensembl chrNW_004955541:2,683,408...2,687,102
JBrowse link
G Gmnn geminin DNA replication inhibitor involved_in ISO (PMID:24064211) ComplexPortal PMID:24064211 NCBI chrNW_004955483:2,283,518...2,344,982
Ensembl chrNW_004955483:2,282,485...2,293,924
JBrowse link
G Kat7 lysine acetyltransferase 7 involved_in ISO (PMID:26620551) UniProt PMID:26620551 NCBI chrNW_004955451:11,770,201...11,802,992
Ensembl chrNW_004955451:11,770,201...11,802,992
JBrowse link
G Mcidas multiciliate differentiation and DNA synthesis associated cell cycle protein involved_in ISO (PMID:24064211) ComplexPortal PMID:24064211 NCBI chrNW_004955446:12,438,737...12,445,254
Ensembl chrNW_004955446:12,438,737...12,445,254
JBrowse link
G Ticrr TOPBP1 interacting checkpoint and replication regulator involved_in ISO (PMID:20116089) UniProt PMID:20116089 NCBI chrNW_004955416:15,572,789...15,615,556
Ensembl chrNW_004955416:15,572,331...15,615,603
JBrowse link
G Wrnip1 WRN helicase interacting protein 1 involved_in ISO (PMID:15670210) UniProt PMID:15670210 NCBI chrNW_004955465:10,574,601...10,594,570
Ensembl chrNW_004955465:10,574,551...10,593,780
JBrowse link
regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl4 methyltransferase 4, N6-adenosine involved_in ISO (PMID:32183942) UniProt PMID:32183942 NCBI chrNW_004955402:7,733,220...7,762,756
Ensembl chrNW_004955402:7,732,627...7,763,038
JBrowse link
regulation of mitotic cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO (PMID:15980864) MGI PMID:15980864 NCBI chrNW_004955537:82,724...134,609
Ensembl chrNW_004955537:81,920...134,609
JBrowse link
regulation of nuclear cell cycle DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 acts_upstream_of_or_within ISO (PMID:11850834) MGI PMID:11850834 NCBI chrNW_004955541:2,683,030...2,687,883
Ensembl chrNW_004955541:2,683,408...2,687,102
JBrowse link
G Dach1 dachshund family transcription factor 1 involved_in ISO (PMID:16980615) CACAO PMID:16980615 NCBI chrNW_004955404:34,739,780...35,118,037
Ensembl chrNW_004955404:34,740,026...35,137,490
JBrowse link
G Ilkap ILK associated serine/threonine phosphatase ISO RGD PMID:9857069 RGD:632254 NCBI chrNW_004955542:2,391,432...2,407,559
Ensembl chrNW_004955542:2,391,431...2,408,732
JBrowse link
G Nuggc nuclear GTPase, germinal center associated involved_in ISO (PMID:19734146) UniProt PMID:19734146 NCBI chrNW_004955403:50,507,971...50,558,881
Ensembl chrNW_004955403:50,507,116...50,558,826
JBrowse link
replication fork arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slfn11 schlafen family member 11 involved_in ISO (PMID:29395061) UniProt PMID:29395061 NCBI chrNW_004955481:9,885,798...9,900,330 JBrowse link
replication fork processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asf1a anti-silencing function 1A histone chaperone involved_in ISO (PMID:29478807) UniProt PMID:29478807 NCBI chrNW_004955436:1,635,397...1,640,989
Ensembl chrNW_004955436:1,635,399...1,645,075
JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (PMID:29125140) UniProt PMID:29125140 NCBI chrNW_004955508:3,337,036...3,440,313
Ensembl chrNW_004955508:3,337,432...3,440,257
JBrowse link
G Atrx ATRX chromatin remodeler involved_in ISO (PMID:24651726) UniProt PMID:24651726 NCBI chrNW_004955557:947,368...1,252,701
Ensembl chrNW_004955557:947,167...1,252,724
JBrowse link
G Blm BLM RecQ like helicase involved_in ISO (PMID:17115688)
(PMID:29125140)
UniProt PMID:17115688 PMID:29125140 NCBI chrNW_004955416:14,814,753...14,899,865
Ensembl chrNW_004955416:14,842,033...14,899,687
JBrowse link
G Bod1l1 biorientation of chromosomes in cell division 1 like 1 involved_in ISO (PMID:26166705) UniProt PMID:26166705 NCBI chrNW_004955480:10,143,053...10,189,194
Ensembl chrNW_004955480:10,142,739...10,189,322
JBrowse link
G Brca2 BRCA2 DNA repair associated acts_upstream_of_or_within ISO (PMID:14681210) MGI PMID:14681210 NCBI chrNW_004955431:13,449,287...13,526,878
Ensembl chrNW_004955431:13,449,543...13,527,432
JBrowse link
G Cdk9 cyclin dependent kinase 9 involved_in ISO (PMID:20930849) UniProt PMID:20930849 NCBI chrNW_004955419:874,959...883,160
Ensembl chrNW_004955419:873,289...883,160
JBrowse link
G Cenps centromere protein S involved_in ISO (PMID:20347428) UniProt PMID:20347428 NCBI chrNW_004955486:3,157,535...3,167,424
Ensembl chrNW_004955486:3,157,535...3,167,397
JBrowse link
G Cenpx centromere protein X involved_in ISO (PMID:20347428) UniProt PMID:20347428 NCBI chrNW_004955506:1,149,566...1,151,919
Ensembl chrNW_004955506:1,149,566...1,151,919
JBrowse link
G Ddx11 DEAD/H-box helicase 11 involved_in ISO (PMID:26503245) UniProt PMID:26503245 NCBI chrNW_004955524:1,932,988...1,957,231
Ensembl chrNW_004955524:1,932,729...1,957,231
JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) UniProt PMID:28191891 NCBI chrNW_004955407:33,007,257...33,014,600
Ensembl chrNW_004955407:33,007,257...33,015,039
JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 involved_in ISO (PMID:18413719) ComplexPortal PMID:18413719 NCBI chrNW_004955451:11,328,759...11,336,099
Ensembl chrNW_004955451:11,329,601...11,334,372
JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 involved_in ISO (PMID:17289582) ComplexPortal PMID:17289582 NCBI chrNW_004955442:15,492,925...15,496,639
Ensembl chrNW_004955442:15,493,911...15,496,620
JBrowse link
G Etaa1 ETAA1 activator of ATR kinase involved_in ISO (PMID:27723717), (PMID:27723720) UniProt PMID:27723717 PMID:27723720 NCBI chrNW_004955424:17,271,690...17,321,276
Ensembl chrNW_004955424:17,307,963...17,320,007
JBrowse link
G Exd2 exonuclease 3'-5' domain containing 2 involved_in ISO (PMID:31255466) UniProt PMID:31255466 NCBI chrNW_004955466:1,114,299...1,169,124
Ensembl chrNW_004955466:1,110,395...1,169,242
JBrowse link
G Fam111a FAM111 trypsin like peptidase A involved_in ISO (PMID:32165630) UniProt PMID:32165630 NCBI chrNW_004955511:3,722,483...3,736,001
Ensembl chrNW_004955511:3,731,116...3,740,140
JBrowse link
G Fancm FA complementation group M involved_in ISO (PMID:20347428) UniProt PMID:20347428 NCBI chrNW_004955409:16,751,658...16,809,352 JBrowse link
G Fbh1 F-box DNA helicase 1 involved_in ISO (PMID:24108124)
(PMID:25585578)
UniProt PMID:24108124 PMID:25585578 NCBI chrNW_004955421:22,535,777...22,579,965
Ensembl chrNW_004955421:22,535,777...22,579,965
JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in ISO (PMID:26578604) UniProt PMID:26578604 NCBI chrNW_004955469:552,850...590,792
Ensembl chrNW_004955469:552,677...592,137
JBrowse link
G LOC102020128 histone-lysine N-methyltransferase SETMAR involved_in ISO (PMID:20457750), (PMID:22231448), (PMID:24573677) UniProt PMID:20457750 PMID:22231448 PMID:24573677 NCBI chrNW_004955421:9,066,906...9,080,352 JBrowse link
G Mms22l MMS22 like, DNA repair protein involved_in ISO (PMID:21055983), (PMID:21055984), (PMID:21055985)
(PMID:21113133), (PMID:27797818)
UniProt PMID:21055983 PMID:21055984 PMID:21055985 PMID:21113133 PMID:27797818 NCBI chrNW_004955411:23,125,203...23,245,941
Ensembl chrNW_004955411:23,125,121...23,245,950
JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit involved_in ISO (PMID:17289582), (PMID:18413719) ComplexPortal PMID:17289582 PMID:18413719 NCBI chrNW_004955422:19,471,552...19,479,121
Ensembl chrNW_004955422:19,471,552...19,479,121
JBrowse link
G Nucks1 nuclear casein kinase and cyclin dependent kinase substrate 1 involved_in ISO (PMID:26323318) ParkinsonsUK-UCL PMID:26323318 NCBI chrNW_004955406:41,412,855...41,448,551
Ensembl chrNW_004955406:41,417,983...41,449,177
JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO (PMID:24115439) BHF-UCL PMID:24115439 NCBI chrNW_004955415:15,744,601...15,748,910
Ensembl chrNW_004955415:15,744,601...15,749,673
JBrowse link
G Polq DNA polymerase theta involved_in ISO (PMID:30655289) UniProt PMID:30655289 NCBI chrNW_004955427:20,779,332...20,895,094
Ensembl chrNW_004955427:20,778,952...20,894,989
JBrowse link
G Primpol primase and DNA directed polymerase involved_in ISO (PMID:24126761), (PMID:24240614), (PMID:24267451)
(PMID:28534480)
UniProt PMID:24126761 PMID:24240614 PMID:24267451 PMID:28534480 NCBI chrNW_004955403:24,278,727...24,307,312
Ensembl chrNW_004955403:24,279,122...24,303,682
JBrowse link
G Rad51 RAD51 recombinase involved_in
acts_upstream_of_or_within
ISO (PMID:22778135)
(PMID:18417535), (PMID:25585578)
BHF-UCL
MGI
UniProt
PMID:18417535 PMID:22778135 PMID:25585578 NCBI chrNW_004955416:7,566,715...7,590,628
Ensembl chrNW_004955416:7,566,686...7,590,628
JBrowse link
G Recql RecQ like helicase involved_in ISO (PMID:35025765) UniProt PMID:35025765 NCBI chrNW_004955413:17,115,443...17,148,708
Ensembl chrNW_004955413:17,113,408...17,148,708
JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:26474068) UniProt PMID:26474068 NCBI chrNW_004955484:2,824,057...2,857,321
Ensembl chrNW_004955484:2,824,422...2,858,283
JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (PMID:24115439) BHF-UCL PMID:24115439 NCBI chrNW_004955528:531,680...578,003
Ensembl chrNW_004955528:532,385...572,398
JBrowse link
G Smarcal1 SNF2 related chromatin remodeling annealing helicase 1 involved_in ISO (PMID:19793862) UniProt PMID:19793862 NCBI chrNW_004955453:16,724,286...16,784,129
Ensembl chrNW_004955453:16,719,931...16,784,709
JBrowse link
G Timeless timeless circadian regulator involved_in ISO (PMID:26503245) UniProt PMID:26503245 NCBI chrNW_004955458:3,999,143...4,029,523
Ensembl chrNW_004955458:3,997,725...4,029,766
JBrowse link
G Tonsl tonsoku like, DNA repair protein involved_in ISO (PMID:21055983), (PMID:21055984), (PMID:21055985)
(PMID:27338793), (PMID:29478807)
UniProt PMID:21055983 PMID:21055984 PMID:21055985 PMID:27338793 PMID:29478807 NCBI chrNW_004955454:3,054,727...3,067,785
Ensembl chrNW_004955454:3,054,400...3,068,028
JBrowse link
G Traip TRAF interacting protein involved_in ISO (PMID:26711499)
(PMID:27462463)
UniProt PMID:26711499 PMID:27462463 NCBI chrNW_004955532:1,725,608...1,746,690
Ensembl chrNW_004955532:1,726,061...1,746,591
JBrowse link
G Wrn WRN RecQ like helicase involved_in ISO (PMID:17115688)
(PMID:12882351)
UniProt PMID:12882351 PMID:17115688 NCBI chrNW_004955463:7,495,243...7,633,532
Ensembl chrNW_004955463:7,525,100...7,633,596
JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 involved_in ISO (PMID:22704558), (PMID:22705370) UniProt PMID:22704558 PMID:22705370 NCBI chrNW_004955440:2,683,041...2,907,859
Ensembl chrNW_004955440:2,680,787...2,888,345
JBrowse link
replication fork reversal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carm1 coactivator associated arginine methyltransferase 1 involved_in ISO (PMID:33412112) UniProt PMID:33412112 NCBI chrNW_004955495:1,983,599...2,002,174
Ensembl chrNW_004955495:1,983,599...2,002,174
JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:33412112) UniProt PMID:33412112 NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615
JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 involved_in ISO (PMID:22704558) UniProt PMID:22704558 NCBI chrNW_004955440:2,683,041...2,907,859
Ensembl chrNW_004955440:2,680,787...2,888,345
JBrowse link
telomere maintenance via semi-conservative replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Upf1 UPF1 RNA helicase and ATPase involved_in ISO (PMID:21829167) BHF-UCL PMID:21829167 NCBI chrNW_004955524:2,798,336...2,814,063
Ensembl chrNW_004955524:2,798,336...2,913,176
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12563
    cellular process 12002
      metabolic process 7932
        macromolecule metabolic process 6501
          nucleic acid metabolic process 3511
            DNA metabolic process 757
              DNA replication 216
                DNA-templated DNA replication 121
                  DNA replication initiation + 22
                  DNA replication termination + 0
                  DNA replication, synthesis of primer 5
                  DNA strand elongation involved in DNA replication + 2
                  DNA-templated DNA replication maintenance of fidelity + 48
                  cell cycle DNA replication + 27
                  mitochondrial DNA replication + 18
                  negative regulation of DNA-templated DNA replication + 7
                  plastid DNA replication 0
                  positive regulation of DNA-templated DNA replication + 14
                  pre-replicative complex assembly + 0
                  regulation of DNA-templated DNA replication + 30
                  replication of extrachromosomal circular DNA 0
                  rolling circle DNA replication 0
                  theta DNA replication 0
Path 2
Term Annotations click to browse term
  biological_process 12563
    cellular process 12002
      metabolic process 7932
        primary metabolic process 6950
          nucleobase-containing compound metabolic process 3907
            nucleic acid metabolic process 3511
              DNA metabolic process 757
                DNA replication 216
                  DNA-templated DNA replication 121
                    DNA replication initiation + 22
                    DNA replication termination + 0
                    DNA replication, synthesis of primer 5
                    DNA strand elongation involved in DNA replication + 2
                    DNA-templated DNA replication maintenance of fidelity + 48
                    cell cycle DNA replication + 27
                    mitochondrial DNA replication + 18
                    negative regulation of DNA-templated DNA replication + 7
                    plastid DNA replication 0
                    positive regulation of DNA-templated DNA replication + 14
                    pre-replicative complex assembly + 0
                    regulation of DNA-templated DNA replication + 30
                    replication of extrachromosomal circular DNA 0
                    rolling circle DNA replication 0
                    theta DNA replication 0
paths to the root