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ONTOLOGY REPORT - ANNOTATIONS


Term:pyrimidine nucleotide catabolic process
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Accession:GO:0006244 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
Synonyms:exact_synonym: pyrimidine nucleotide breakdown;   pyrimidine nucleotide catabolism;   pyrimidine nucleotide degradation


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dCTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCTPP1 dCTP pyrophosphatase 1 IMP
IBA
(PMID:24467396)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:24467396 NCBI chr16:30,423,615...30,430,030
Ensembl chr16:30,423,615...30,430,030
JBrowse link
depyrimidination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MBD4 methyl-CpG binding domain 4, DNA glycosylase TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr 3:129,430,947...129,440,029
Ensembl chr 3:129,430,944...129,440,179
JBrowse link
G NEIL1 nei like DNA glycosylase 1 TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr15:75,346,638...75,357,115
Ensembl chr15:75,346,955...75,357,115
JBrowse link
G NEIL2 nei like DNA glycosylase 2 TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr 8:11,769,710...11,787,345
Ensembl chr 8:11,769,639...11,787,345
JBrowse link
G NTHL1 nth like DNA glycosylase 1 TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr16:2,039,820...2,047,834
Ensembl chr16:2,039,815...2,047,866
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr 3:9,749,952...9,788,246
Ensembl chr 3:9,749,944...9,788,219
JBrowse link
G SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr12:54,121,274...54,188,985
Ensembl chr12:54,121,277...54,189,008
JBrowse link
G TDG thymine DNA glycosylase TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr12:103,965,842...103,988,874
Ensembl chr12:103,965,822...103,988,874
JBrowse link
G UNG uracil DNA glycosylase TAS Reactome Reactome:R-HSA-110328, Reactome:R-HSA-110329 NCBI chr12:109,097,597...109,110,992
Ensembl chr12:109,097,574...109,110,992
Ensembl chr12:109,097,574...109,110,992
JBrowse link
dTTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCTPP1 dCTP pyrophosphatase 1 NOT IMP (PMID:24467396) UniProtKB PMID:24467396 NCBI chr16:30,423,615...30,430,030
Ensembl chr16:30,423,615...30,430,030
JBrowse link
dUMP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NT5M 5',3'-nucleotidase, mitochondrial IEA Ensembl GO_REF:0000107 NCBI chr17:17,303,373...17,347,663
Ensembl chr17:17,303,335...17,347,663
JBrowse link
dUTP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AL353753.1 putative deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:26,066,675...26,126,108
Ensembl chr 9:26,066,675...26,118,408
JBrowse link
G DUT deoxyuridine triphosphatase IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000104 NCBI chr15:48,329,991...48,343,373
Ensembl chr15:48,331,011...48,343,373
JBrowse link
pyrimidine deoxyribonucleotide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NT5C 5', 3'-nucleotidase, cytosolic IDA
IBA
(PMID:10681516)
(PMID:21873635)
UniProtKB
GO_Central
PMID:10681516, PMID:21873635 NCBI chr17:75,130,228...75,131,965
Ensembl chr17:75,130,225...75,131,757
JBrowse link
G NT5M 5',3'-nucleotidase, mitochondrial IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:17,303,373...17,347,663
Ensembl chr17:17,303,335...17,347,663
JBrowse link
UDP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 IDA (PMID:9556635) UniProtKB PMID:9556635 NCBI chr 8:23,429,162...23,457,647
Ensembl chr 8:23,385,783...23,457,695
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18672
    cellular process 17690
      cellular metabolic process 11278
        cellular nitrogen compound metabolic process 6772
          cellular nitrogen compound catabolic process 631
            pyrimidine-containing compound catabolic process 45
              pyrimidine nucleotide catabolic process 14
                pyrimidine deoxyribonucleotide catabolic process + 13
                pyrimidine ribonucleotide catabolic process + 1
Path 2
Term Annotations click to browse term
  biological_process 18672
    metabolic process 12302
      cellular metabolic process 11278
        cellular aromatic compound metabolic process 6222
          nucleobase-containing compound metabolic process 5984
            nucleobase-containing small molecule metabolic process 672
              nucleoside phosphate metabolic process 582
                nucleotide metabolic process 574
                  pyrimidine nucleotide metabolic process 48
                    pyrimidine nucleotide catabolic process 14
                      pyrimidine deoxyribonucleotide catabolic process + 13
                      pyrimidine ribonucleotide catabolic process + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.