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ONTOLOGY REPORT - ANNOTATIONS


Term:cGMP biosynthetic process
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Accession:GO:0006182 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate.
Synonyms:exact_synonym: cGMP anabolism;   cGMP biosynthesis;   cGMP formation;   cGMP synthesis


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cGMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3640802 (MGI:3640061|PMID:16614755)
(PMID:23505436)
Ensembl
RGD
PMID:16614755 PMID:23505436 GO_REF:0000107 MGI:3640061 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:500,212...900,201
Ensembl chr 8:500,212...889,203
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 involved_in ISO (PMID:23505436) RGD PMID:23505436 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
JBrowse link
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 involved_in IEA GO_REF:0000002
GO_REF:0000043
InterPro
UniProt
GO_REF:0000002 GO_REF:0000043 NCBI chr15:36,589,501...36,669,441
Ensembl chr15:36,598,883...36,669,441
JBrowse link
G Gucy2c guanylate cyclase 2C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:169,568,505...169,649,092
Ensembl chr 4:169,568,529...169,649,092
JBrowse link
G Gucy2d guanylate cyclase 2D, retinal involved_in IEA
ISO
IBA
GO_REF:0000107
(MGI:5049799|PMID:21598940)
PMID:21873635
Ensembl
RGD
PMID:21598940 PMID:21873635 GO_REF:0000107 MGI:5049799, RGD:13792537 NCBI chr10:53,954,918...53,975,576
Ensembl chr10:53,959,010...53,974,067
JBrowse link
G Gucy2e guanylate cyclase 2E involved_in IBA
IDA
PMID:21873635
PMID:11580282
GO_Central
UniProt
PMID:21873635 PMID:11580282 RGD:13792537, RGD:15023466 NCBI chr 1:152,739,775...152,774,474
Ensembl chr 1:152,739,775...152,774,473
JBrowse link
G Gucy2f guanylate cyclase 2F involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:105,710,356...105,808,183
Ensembl chr  X:105,710,356...105,808,183
JBrowse link
G Gucy2g guanylate cyclase 2G involved_in IBA
IEA
PMID:21873635
GO_REF:0000043
UniProt PMID:21873635 GO_REF:0000043, RGD:13792537 NCBI chr 1:254,237,778...254,280,277
Ensembl chr 1:254,239,174...254,280,277
JBrowse link
G Nppa natriuretic peptide A involved_in
acts_upstream_of
IBA
ISO
PMID:21873635
(PMID:1672777)
RGD PMID:1672777 PMID:21873635 RGD:13792537 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B acts_upstream_of
involved_in
ISO
IBA
(PMID:1672777)
PMID:21873635
RGD PMID:1672777 PMID:21873635 RGD:13792537 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nppc natriuretic peptide C involved_in
acts_upstream_of
IBA
ISO
PMID:21873635
(MGI:2177134|PMID:11259675)
(PMID:1672777)
RGD PMID:1672777 PMID:11259675 PMID:21873635 MGI:2177134, RGD:13792537 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
JBrowse link
G Npr1 natriuretic peptide receptor 1 involved_in IBA
ISO
PMID:21873635
(PMID:1672777)
RGD PMID:1672777 PMID:21873635 RGD:13792537 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505
JBrowse link
G Npr2 natriuretic peptide receptor 2 acts_upstream_of
involved_in
ISO
IBA
(PMID:1672777)
PMID:21873635
RGD PMID:1672777 PMID:21873635 RGD:13792537 NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      organic substance metabolic process 11335
        organic substance biosynthetic process 5972
          carbohydrate derivative biosynthetic process 576
            ribose phosphate biosynthetic process 187
              ribonucleotide biosynthetic process 180
                purine ribonucleotide biosynthetic process 166
                  cGMP biosynthetic process 14
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      cellular metabolic process 10721
        cellular aromatic compound metabolic process 5598
          nucleobase-containing compound metabolic process 5380
            nucleobase-containing small molecule metabolic process 577
              nucleoside phosphate metabolic process 510
                nucleotide metabolic process 502
                  purine nucleotide metabolic process 426
                    purine ribonucleotide metabolic process 400
                      cGMP metabolic process 21
                        cGMP biosynthetic process 14
paths to the root