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ONTOLOGY REPORT - ANNOTATIONS


Term:glycerophosphate shuttle
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Accession:GO:0006127 term browser browse the term
Definition:The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.
Synonyms:xref: MetaCyc:PWY-6118



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glycerophosphate shuttle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) acts_upstream_of_or_within IMP (PMID:11147825) MGI PMID:11147825 NCBI chr15:99,615,468...99,622,895
Ensembl chr15:99,615,396...99,622,886
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G Slc37a2 solute carrier family 37 (glycerol-3-phosphate transporter), member 2 acts_upstream_of_or_within ISA (PMID:11112347) MGI PMID:11112347 NCBI chr 9:37,140,445...37,166,709
Ensembl chr 9:37,138,881...37,167,034
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    metabolic process 11001
      organic substance metabolic process 10573
        organic hydroxy compound metabolic process 591
          phenol-containing compound metabolic process 143
            glycerophosphate shuttle 2
Path 2
Term Annotations click to browse term
  biological_process 28573
    metabolic process 11001
      organic substance metabolic process 10573
        organic cyclic compound metabolic process 5906
          nucleobase-containing compound metabolic process 5390
            nucleobase-containing small molecule metabolic process 667
              nucleoside phosphate metabolic process 608
                nucleotide metabolic process 600
                  pyridine nucleotide metabolic process 189
                    nicotinamide nucleotide metabolic process 187
                      NAD metabolic process 61
                        NADH metabolic process 40
                          NADH oxidation 7
                            glycerophosphate shuttle 2
paths to the root