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Term:glycerophosphate shuttle
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Accession:GO:0006127 term browser browse the term
Definition:The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.
Synonyms:xref: MetaCyc:PWY-6118

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glycerophosphate shuttle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPD1 glycerol-3-phosphate dehydrogenase 1 acts_upstream_of_or_within
(MGI:1927687|PMID:11147825) MGI
PMID:11147825 GO_REF:0000107 MGI:1927687 NCBI chr27:4,614,878...4,622,013
Ensembl chr27:4,614,864...4,621,922
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16442
    metabolic process 10767
      NADH metabolic process 39
        NADH oxidation 5
          glycerophosphate shuttle 1
Path 2
Term Annotations click to browse term
  biological_process 16442
    cellular process 15494
      cellular metabolic process 9094
        generation of precursor metabolites and energy 442
          energy derivation by oxidation of organic compounds 311
            cellular respiration 217
              respiratory electron transport chain 97
                glycerophosphate shuttle 1
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