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Term:glycerophosphate shuttle
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Accession:GO:0006127 term browser browse the term
Definition:The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.
Synonyms:xref: MetaCyc:PWY-6118

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glycerophosphate shuttle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPD1 glycerol-3-phosphate dehydrogenase 1 acts_upstream_of_or_within
(MGI:1927687|PMID:11147825) MGI
PMID:11147825 GO_REF:0000107 MGI:1927687 NCBI chr12:38,644,466...38,651,924
Ensembl chr12:39,541,550...39,549,040
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15332
    metabolic process 10016
      NADH metabolic process 35
        NADH oxidation 4
          glycerophosphate shuttle 1
Path 2
Term Annotations click to browse term
  biological_process 15332
    cellular process 14173
      cellular metabolic process 8332
        generation of precursor metabolites and energy 428
          energy derivation by oxidation of organic compounds 295
            cellular respiration 206
              respiratory electron transport chain 88
                glycerophosphate shuttle 1
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