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Term:glycerophosphate shuttle
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Accession:GO:0006127 term browser browse the term
Definition:The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.
Synonyms:xref: MetaCyc:PWY-6118

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glycerophosphate shuttle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpd1 glycerol-3-phosphate dehydrogenase 1 acts_upstream_of_or_within ISO MGI:3692960 (MGI:1927687|PMID:11147825) RGD PMID:11147825 MGI:1927687 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
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Term Annotations click to browse term
  biological_process 19553
    metabolic process 11538
      cellular metabolic process 10124
        cellular ketone metabolic process 256
          glycerophosphate shuttle 1
Path 2
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  biological_process 19553
    metabolic process 11538
      organic substance metabolic process 10895
        organic cyclic compound metabolic process 6033
          nucleobase-containing compound metabolic process 5539
            nucleobase-containing small molecule metabolic process 684
              nucleoside phosphate metabolic process 612
                nucleotide metabolic process 602
                  pyridine nucleotide metabolic process 212
                    nicotinamide nucleotide metabolic process 212
                      NAD metabolic process 56
                        NADH metabolic process 34
                          NADH oxidation 5
                            glycerophosphate shuttle 1
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