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ONTOLOGY REPORT - ANNOTATIONS
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Term:
fumarate metabolic process
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Accession:
GO:0006106
browse the term
Definition:
The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.
Synonyms:
exact_synonym:
fumarate metabolism
show annotations for term's descendants Sort by:
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reference
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Rat (3)
Mouse (3)
Human (3)
Chinchilla (3)
Bonobo (3)
Dog (3)
Squirrel (2)
Pig (3)
All
Genes (3)
fumarate metabolic process
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Fh
fumarate hydratase
involved_in
TAS
ISO
ISS
IBA
IDA
(MGI:5496931|PMID:23643539)
GO_REF:0000024
(PMID:21498518)
(PMID:26237645), (PMID:30718813)
(PMID:30761759)
PMID:21873635
RGD
UniProt
PMID:21498518
PMID:23643539
PMID:26237645
PMID:30718813
PMID:30761759
,
PMID:2914923
,
PMID:21873635
,
PMID:938457
GO_REF:0000024
MGI:5496931
,
RGD:632664
,
RGD:13792537
,
RGD:2306828
NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377
glutamate catabolic process to 2-oxoglutarate
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Got1
glutamic-oxaloacetic transaminase 1
acts_upstream_of_or_within
IDA
ISO
(MGI:53641|PMID:4193185)
RGD
PMID:4193185
,
PMID:16489927
MGI:53641
,
RGD:13504861
NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
G
Got2
glutamic-oxaloacetic transaminase 2
acts_upstream_of_or_within
IDA
ISO
(MGI:53641|PMID:4193185)
RGD
PMID:4193185
,
PMID:16489927
MGI:53641
,
RGD:13504861
NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
Term paths to the root
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all shortest
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Path 1
Term
Annotations
biological_process
19634
metabolic process
11911
cellular metabolic process
10866
organic acid metabolic process
1004
oxoacid metabolic process
966
carboxylic acid metabolic process
948
dicarboxylic acid metabolic process
104
fumarate metabolic process
3
2,5-dihydroxypyridine catabolic process to fumarate
0
glutamate catabolic process to 2-oxoglutarate
2
glutamine catabolic process to fumarate
+
0
tyrosine catabolic process to fumarate
0