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ONTOLOGY REPORT - ANNOTATIONS

Term:UDP-N-acetylglucosamine biosynthetic process
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Accession:GO:0006048 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
Synonyms:exact_synonym: UDP-GlcNAc biosynthesis;   UDP-GlcNAc biosynthetic process;   UDP-N-acetylglucosamine anabolism;   UDP-N-acetylglucosamine biosynthesis;   UDP-N-acetylglucosamine formation;   UDP-N-acetylglucosamine synthesis
 xref: Reactome:R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine"


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UDP-N-acetylglucosamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07059877.1 involved_in IEA GO_REF:0000041
GO_REF:0000104 		UniProt GO_REF:0000041 GO_REF:0000104 Ensembl chr 4:41,548,914...41,549,455 JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 involved_in IEA
ISO
ISS 		GO_REF:0000041
(PMID:26887390), (PMID:35229715)
GO_REF:0000024 		UniProt
RGD		 PMID:26887390 PMID:35229715 GO_REF:0000024 GO_REF:0000041 NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471 		JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 involved_in IEA
ISO 		GO_REF:0000041
(PMID:35229715)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:35229715 GO_REF:0000041 GO_REF:0000107 NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329 		JBrowse link
G Gnpda1 glucosamine-6-phosphate deaminase 1 involved_in ISO
IEA 		(PMID:26887390)
GO_REF:0000107
GO_REF:0000041 		RGD
Ensembl
UniProt		 PMID:26887390 GO_REF:0000041 GO_REF:0000107 NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486 		JBrowse link
G Gnpda2 glucosamine-6-phosphate deaminase 2 involved_in ISO
IEA 		(PMID:26887390)
GO_REF:0000107
GO_REF:0000041 		RGD
Ensembl
UniProt		 PMID:26887390 GO_REF:0000041 GO_REF:0000107 NCBI chr14:38,520,663...38,538,713
Ensembl chr14:38,520,705...38,538,713 		JBrowse link
G Gnpnat1 glucosamine-phosphate N-acetyltransferase 1 involved_in IEA
ISO 		GO_REF:0000041
GO_REF:0000104
(PMID:11013212) 		UniProt
RGD		 PMID:11013212 GO_REF:0000041 GO_REF:0000104 NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739 		JBrowse link
G Nagk N-acetylglucosamine kinase involved_in ISO (PMID:34844667) RGD PMID:34844667 NCBI chr 4:116,281,179...116,293,870
Ensembl chr 4:116,281,328...116,313,137 		JBrowse link
G Pgm3 phosphoglucomutase 3 involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		(PMID:24589341)
GO_REF:0000104
MGI:3758645 (PMID:17548465)
GO_REF:0000033
GO_REF:0000041 		RGD
UniProt
GO_Central		 PMID:17548465 PMID:24589341 GO_REF:0000033 GO_REF:0000041 GO_REF:0000104 NCBI chr 8:87,518,317...87,536,021
Ensembl chr 8:87,517,701...87,536,022 		JBrowse link
G Uap1 UDP-N-acetylglucosamine pyrophosphorylase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:82,342,946...82,377,558
Ensembl chr13:82,342,946...82,377,469
Ensembl chr 6:82,342,946...82,377,469 		JBrowse link
G Uap1l1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:8,172,335...8,180,505
Ensembl chr 3:8,173,216...8,180,443 		JBrowse link
G Uap1l2 UDP-N-acetylglucosamine pyrophosphorylase 1 like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:1,714,320...1,741,396 JBrowse link
negative regulation of UDP-N-acetylglucosamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amdhd2 amidohydrolase domain containing 2 involved_in ISO
IEA 		(PMID:35229715)
GO_REF:0000107 		RGD
Ensembl		 PMID:35229715 GO_REF:0000107 NCBI chr10:13,187,579...13,196,148
Ensembl chr10:13,187,578...13,196,095 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        carbohydrate derivative metabolic process 1062
          amino sugar metabolic process 46
            UDP-N-acetylglucosamine metabolic process 15
              UDP-N-acetylglucosamine biosynthetic process 12
                negative regulation of UDP-N-acetylglucosamine biosynthetic process 1
                positive regulation of UDP-N-acetylglucosamine biosynthetic process 0
                regulation of UDP-N-acetylglucosamine biosynthetic process + 1
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        primary metabolic process 10727
          nucleobase-containing compound metabolic process 5900
            nucleobase-containing small molecule metabolic process 730
              nucleoside phosphate metabolic process 699
                nucleotide-sugar metabolic process 50
                  nucleotide-sugar biosynthetic process 34
                    UDP-N-acetylglucosamine biosynthetic process 12
                      negative regulation of UDP-N-acetylglucosamine biosynthetic process 1
                      positive regulation of UDP-N-acetylglucosamine biosynthetic process 0
                      regulation of UDP-N-acetylglucosamine biosynthetic process + 1
paths to the root