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ONTOLOGY REPORT - ANNOTATIONS


Term:glycosaminoglycan catabolic process
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Accession:GO:0006027 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.
Synonyms:exact_synonym: glycosaminoglycan breakdown;   glycosaminoglycan catabolism;   glycosaminoglycan degradation



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glycosaminoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyal2 hyaluronidase 2 involved_in ISO
ISS
(PMID:9712871)
GO_REF:0000024
RGD
UniProt
PMID:9712871 GO_REF:0000024 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850
JBrowse link
G Hyal4 hyaluronidase 4 TAS RGD PMID:10989127 RGD:1331360 NCBI chr 4:53,256,179...53,274,819
Ensembl chr 4:53,256,179...53,274,819
JBrowse link
G Ids iduronate 2-sulfatase involved_in ISO (PMID:28593992) RGD PMID:28593992 NCBI chr  X:149,025,976...149,046,641
Ensembl chr  X:149,025,976...149,046,663
JBrowse link
G Idua alpha-L-iduronidase acts_upstream_of_or_within IDA
ISO
MGI:2176236|MGI:2651471|MGI:4415188 (MGI:3697540|PMID:16979922), (MGI:4397742|PMID:19834056), (MGI:4414887|PMID:19751987), (MGI:5295514|PMID:21873421), (MGI:5448924|PMID:22580166) RGD PMID:16979922 PMID:19751987 PMID:19834056 PMID:21873421 PMID:22580166 More... MGI:3697540 MGI:4397742 MGI:4414887 MGI:5295514 MGI:5448924, RGD:1599427 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 acts_upstream_of_or_within ISO (MGI:2135409|PMID:11278811) RGD PMID:11278811 MGI:2135409 NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309
JBrowse link
G Sgsh N-sulfoglucosamine sulfohydrolase involved_in ISO (PMID:15146460), (PMID:7493035) RGD PMID:7493035 PMID:15146460 NCBI chr10:104,596,810...104,613,510
Ensembl chr10:104,598,112...104,613,486
JBrowse link
chondroitin sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gusb glucuronidase, beta involved_in ISO MGI:1856041 (MGI:7281718|PMID:23897660) RGD PMID:23897660 MGI:7281718 NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G Hexb hexosaminidase subunit beta involved_in ISO
IEA
MGI:2429701 (MGI:5428797|PMID:22451654)
GO_REF:0000107
RGD
Ensembl
PMID:22451654 GO_REF:0000107 MGI:5428797 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hyal1 hyaluronidase 1 involved_in ISO
IEA
MGI:2658730 (MGI:5428797|PMID:22451654)
GO_REF:0000107
RGD
Ensembl
PMID:22451654 GO_REF:0000107 MGI:5428797 NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210
JBrowse link
G Hyal4 hyaluronidase 4 acts_upstream_of_or_within ISO (MGI:5490850|PMID:23086929) RGD PMID:23086929 MGI:5490850 NCBI chr 4:53,256,179...53,274,819
Ensembl chr 4:53,256,179...53,274,819
JBrowse link
dermatan sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arsb arylsulfatase B involved_in ISO MGI:3800577 (MGI:5608575|PMID:24240681) RGD PMID:24240681 MGI:5608575 NCBI chr 2:25,002,210...25,162,675
Ensembl chr 2:25,002,346...25,162,671
JBrowse link
G Hexa hexosaminidase subunit alpha involved_in ISO MGI:96074 (MGI:3722584|PMID:11707436) RGD PMID:11707436 MGI:3722584 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
JBrowse link
G Hexb hexosaminidase subunit beta involved_in ISO
IEA
MGI:96073 (MGI:3722584|PMID:11707436)
GO_REF:0000107
RGD
Ensembl
PMID:11707436 GO_REF:0000107 MGI:3722584 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Ids iduronate 2-sulfatase involved_in ISO MGI:5439833 (MGI:7310027|PMID:30064964) RGD PMID:30064964 MGI:7310027 NCBI chr  X:149,025,976...149,046,641
Ensembl chr  X:149,025,976...149,046,663
JBrowse link
G Idua alpha-L-iduronidase involved_in
acts_upstream_of_or_within
ISO (PMID:24036510)
MGI:2176236|MGI:4415188 (MGI:4414887|PMID:19751987), (MGI:7310026|PMID:25854773)
MGI:2176236|MGI:4415188 (MGI:4397742|PMID:19834056), (MGI:4414887|PMID:19751987)
RGD PMID:19751987 PMID:19834056 PMID:24036510 PMID:25854773 MGI:4397742 MGI:4414887 MGI:7310026 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
heparin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO MGI:2176236|MGI:4415188 (MGI:4397742|PMID:19834056), (MGI:4414887|PMID:19751987), (MGI:5295514|PMID:21873421)
(PMID:21873421)
RGD PMID:19751987 PMID:19834056 PMID:21873421 MGI:4397742 MGI:4414887 MGI:5295514 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
hyaluronan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule involved_in ISO
IEA
(PMID:17170110)
(MGI:7264268|PMID:26528478)
GO_REF:0000107
RGD
Ensembl
PMID:17170110 PMID:26528478 GO_REF:0000107 MGI:7264268 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cemip cell migration inducing hyaluronidase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:23509262)
(MGI:5545862|PMID:24251095)
UniProt
RGD
PMID:23509262 PMID:24251095 GO_REF:0000024 MGI:5545862 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 involved_in ISO (MGI:6810380|PMID:34624311) RGD PMID:34624311 MGI:6810380 NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760
JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in ISO (PMID:19577615) RGD PMID:19577615 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Gusb glucuronidase, beta involved_in ISO (MGI:4442520|PMID:20385825) RGD PMID:20385825 MGI:4442520 NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G Hexa hexosaminidase subunit alpha involved_in ISO MGI:2429698 (MGI:5428797|PMID:22451654) RGD PMID:22451654 MGI:5428797 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
JBrowse link
G Hexb hexosaminidase subunit beta involved_in ISO
IEA
MGI:2429701 (MGI:5428797|PMID:22451654)
GO_REF:0000107
RGD
Ensembl
PMID:22451654 GO_REF:0000107 MGI:5428797 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hmmr hyaluronan-mediated motility receptor involved_in ISO (MGI:7264268|PMID:26528478) RGD PMID:26528478 MGI:7264268 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
JBrowse link
G Hyal1 hyaluronidase 1 involved_in ISO
IEA
IBA
(PMID:12084718)
(PMID:11296287), (PMID:17170110), (PMID:20473947), (PMID:21695196), (PMID:21699545), (PMID:21829529)
MGI:2658730 (MGI:5428797|PMID:22451654), (MGI:5828047|PMID:26887442)
GO_REF:0000107
GO_REF:0000118
GO_REF:0000033
RGD
Ensembl
TreeGrafter
GO_Central
PMID:11296287 PMID:12084718 PMID:17170110 PMID:20473947 PMID:21695196 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:5428797 MGI:5828047 NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210
JBrowse link
G Hyal2 hyaluronidase 2 involved_in IDA
ISO
IEA
IBA
PMID:19635555
(PMID:17170110), (PMID:19443707), (PMID:20554532), (PMID:21699545)
GO_REF:0000107
MGI:3836764 (MGI:5469812|PMID:23172227), (MGI:5828047|PMID:26887442)
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:17170110 PMID:19443707 PMID:20554532 PMID:21699545 PMID:23172227 More... GO_REF:0000033 GO_REF:0000107 MGI:5469812 MGI:5828047, RGD:8553259 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850
JBrowse link
G Hyal3 hyaluronidase 3 involved_in ISS
ISO
IEA
IBA
GO_REF:0000024
(PMID:12084718)
(PMID:21699545)
(MGI:4834982|PMID:20586096)
GO_REF:0000002
GO_REF:0000118
GO_REF:0000033
UniProt
RGD
InterPro
TreeGrafter
GO_Central
PMID:12084718 PMID:20586096 PMID:21699545 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:4834982 NCBI chr 8:108,254,385...108,260,020
Ensembl chr 8:108,250,667...108,260,647
JBrowse link
G Hyal4 hyaluronidase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:53,256,179...53,274,819
Ensembl chr 4:53,256,179...53,274,819
JBrowse link
G Hyal5 hyaluronoglucosaminidase 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:53,341,105...53,412,280
Ensembl chr 4:53,343,475...53,370,785
JBrowse link
G Hyal6 hyaluronoglucosaminidase 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:53,238,118...53,250,783
Ensembl chr 4:53,237,983...53,250,783
JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 involved_in ISO (MGI:2135409|PMID:11278811) RGD PMID:11278811 MGI:2135409 NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309
JBrowse link
G Spam1 sperm adhesion molecule 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:53,302,745...53,312,913
Ensembl chr 4:53,302,745...53,312,908
JBrowse link
G Stab2 stabilin 2 involved_in ISO
IEA
MGI:5318244 (MGI:5315050|PMID:22371575)
GO_REF:0000107
RGD
Ensembl
PMID:22371575 GO_REF:0000107 MGI:5315050 NCBI chr 7:21,249,426...21,433,051
Ensembl chr 7:21,249,391...21,434,042
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS
(PMID:17324121)
GO_REF:0000024
RGD
UniProt
PMID:17324121 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
keratan sulfate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gns glucosamine (N-acetyl)-6-sulfatase IDA RGD PMID:3161730 RGD:1600571 NCBI chr 7:56,889,148...56,923,173
Ensembl chr 7:56,889,232...56,923,151
JBrowse link
peptidoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lyg1 lysozyme G1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:40,171,123...40,182,869
Ensembl chr 9:40,171,123...40,182,869
JBrowse link
G Lyg2 lysozyme G2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:40,141,144...40,150,821
Ensembl chr 9:40,141,381...40,150,821
JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:78,531,815...78,537,001
Ensembl chr 1:78,531,815...78,537,001
JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:11,418,674...11,432,162
Ensembl chr 7:11,418,880...11,427,773
JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:177,479,693...177,490,769
Ensembl chr 2:177,477,407...177,490,736
Ensembl chr 2:177,477,407...177,490,736
JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:176,202,654...176,322,859
Ensembl chr 2:176,218,519...176,242,251
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 20295
    metabolic process 11722
      organic substance metabolic process 11223
        macromolecule metabolic process 9475
          aminoglycan metabolic process 120
            aminoglycan catabolic process 37
              glycosaminoglycan catabolic process 29
                chondroitin sulfate catabolic process 4
                dermatan sulfate catabolic process 5
                galactosaminoglycan catabolic process 0
                heparin catabolic process 1
                hyaluronan catabolic process 18
                keratan sulfate catabolic process 1
                peptidoglycan catabolic process 6
paths to the root