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ONTOLOGY REPORT - ANNOTATIONS


Term:fructose 2,6-bisphosphate metabolic process
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Accession:GO:0006003 term browser browse the term
Definition:The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase.
Synonyms:exact_synonym: fructose 2,6-bisphosphate metabolism


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fructose 2,6-bisphosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gck glucokinase ISO Gck and Pfkfb3 act synergistically to increase cellular levels of fructose-2,6-bisphosphate RGD PMID:17553851 RGD:2301905 NCBI chrNW_004955456:7,784,269...7,838,260
Ensembl chrNW_004955456:7,783,760...7,842,129
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in ISO (PMID:2837207) UniProt PMID:2837207 NCBI chrNW_004955475:2,279,390...2,343,881
Ensembl chrNW_004955475:2,279,390...2,342,750
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 ISO Gck and Pfkfb3 act synergistically to increase cellular levels of fructose-2,6-bisphosphate RGD PMID:17553851 RGD:2301905 NCBI chrNW_004955421:22,762,290...22,868,677
Ensembl chrNW_004955421:22,848,548...22,866,035
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
ISO (PMID:19015259)
(MGI:4867601|PMID:20935145)
UniProt
MGI
PMID:19015259 PMID:20935145 MGI:4867601 NCBI chrNW_004955413:2,129,719...2,153,873
Ensembl chrNW_004955413:2,129,678...2,154,380
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12107
    metabolic process 7728
      organic substance metabolic process 7443
        organophosphate metabolic process 656
          fructose 2,6-bisphosphate metabolic process 4
Path 2
Term Annotations click to browse term
  biological_process 12107
    metabolic process 7728
      cellular metabolic process 7085
        phosphorus metabolic process 2124
          phosphate-containing compound metabolic process 2110
            fructose 2,6-bisphosphate metabolic process 4
paths to the root