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ONTOLOGY REPORT - ANNOTATIONS


Term:calcium- and calmodulin-dependent protein kinase complex
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Accession:GO:0005954 term browser browse the term
Definition:An enzyme complex which in eukaryotes is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Catalyzes the phosphorylation of proteins to O-phosphoproteins.
Synonyms:exact_synonym: CAMK2;   calcium/calmodulin-dependent protein kinase complex
 related_synonym: CaMKII


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calcium- and calmodulin-dependent protein kinase complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk1g calcium/calmodulin-dependent protein kinase IG ISO (MGI:MGI:2662679|PMID:12637513) RGD PMID:12637513 MGI:MGI:2662679 NCBI chr13:112,075,689...112,099,472
Ensembl chr13:112,075,690...112,099,336
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:20668654), (PMID:28130356)
UniProt
Ensembl
RGD
PMID:20668654, PMID:28130356 GO_REF:0000024, GO_REF:0000107 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta ISO
IEA
(PMID:20668654)
GO_REF:0000107
RGD
Ensembl
PMID:20668654 GO_REF:0000107 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta ISO (PMID:20668654) RGD PMID:20668654 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma ISO (PMID:20668654) RGD PMID:20668654 NCBI chr15:3,936,721...3,995,740
Ensembl chr15:3,936,786...3,995,915
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20610
    protein-containing complex 6104
      calcium- and calmodulin-dependent protein kinase complex 5
Path 2
Term Annotations click to browse term
  cellular_component 20610
    cellular anatomical entity 20359
      intracellular anatomical structure 14705
        calcium- and calmodulin-dependent protein kinase complex 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.