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ONTOLOGY REPORT - ANNOTATIONS

Term:cAMP-dependent protein kinase complex
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Accession:GO:0005952 term browser browse the term
Definition:An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
Synonyms:exact_synonym: 3',5' cAMP-dependent protein kinase complex;   adenosine 3',5'-cyclophosphate-dependent protein kinase complex;   cyclic AMP-dependent protein kinase complex
 related_synonym: PKA


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cAMP-dependent protein kinase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap14 A-kinase anchoring protein 14 part_of ISO
IBA
IEA		 (PMID:12475942)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:12475942 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:116,395,512...116,410,697
Ensembl chr  X:116,395,516...116,410,697 		JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 IDA RGD PMID:10544261 RGD:631899 NCBI chr 2:185,257,218...185,272,846
Ensembl chr 2:185,257,213...185,269,872 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha part_of IDA
ISO
IEA
IBA		 (PMID:12475942)
(MGI:3694188|PMID:15692043)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:12475942 PMID:15692043 PMID:16816331 PMID:11907174 GO_REF:0000033 GO_REF:0000107 MGI:3694188, RGD:2312556, RGD:2312572 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta part_of IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16816331 PMID:11907174 GO_REF:0000033, RGD:2312556, RGD:2312572 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha part_of IDA
IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000117
GO_REF:0000033
(PMID:21502359)		 InterPro
UniProt
GO_Central
RGD		 PMID:21502359 PMID:16816331 PMID:11907174 GO_REF:0000002 GO_REF:0000033 GO_REF:0000117, RGD:2312556, RGD:2312572 NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041 		JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta part_of IDA
IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000118
GO_REF:0000033
(PMID:21502359)		 InterPro
TreeGrafter
GO_Central
RGD		 PMID:21502359 PMID:16816331 PMID:11907174 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118, RGD:2312556, RGD:2312572 NCBI chr12:15,492,233...15,624,942
Ensembl chr12:15,511,801...15,624,942 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha part_of IDA
ISO
IEA
IBA		 (PMID:12475942)
GO_REF:0000117
GO_REF:0000033
(PMID:21502359)		 RGD
UniProt
GO_Central		 PMID:12475942 PMID:21502359 PMID:16816331 PMID:11907174 GO_REF:0000033 GO_REF:0000117, RGD:2312556, RGD:2312572 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628 		JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta part_of IDA
IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000033
GO_REF:0000118
(PMID:21502359)		 InterPro
GO_Central
TreeGrafter
RGD		 PMID:21502359 PMID:16816331 PMID:11907174 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118, RGD:2312556, RGD:2312572 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933 		JBrowse link
G Prkx protein kinase cAMP-dependent X-linked catalytic subunit part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr  X:41,823,349...41,866,844
Ensembl chr  X:41,823,355...41,866,669 		JBrowse link
Term paths to the root
Path 1
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  cellular_component 21392
    protein-containing complex 6987
      intracellular protein-containing complex 987
        cAMP-dependent protein kinase complex 9
Path 2
Term Annotations click to browse term
  cellular_component 21392
    protein-containing complex 6987
      catalytic complex 1938
        transferase complex 905
          transferase complex, transferring phosphorus-containing groups 291
            protein kinase complex 133
              serine/threonine protein kinase complex 119
                cAMP-dependent protein kinase complex 9
paths to the root