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ONTOLOGY REPORT - ANNOTATIONS

Term:clathrin-coated pit
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Accession:GO:0005905 term browser browse the term
Definition:A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
Synonyms:exact_synonym: coated pit
 xref: NIF_Subcellular:sao1969557946


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clathrin-coated pit term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AAK1 AP2 associated kinase 1 located_in IEA
ISS		 UniProt GO_REF:0000024 GO_REF:0000043 GO_REF:0000044 NCBI chr 3:72,793,977...72,960,315
Ensembl chr 3:72,794,158...72,968,194 		JBrowse link
G ACKR3 atypical chemokine receptor 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr15:136,370,457...136,382,559
Ensembl chr15:136,370,530...136,382,553 		JBrowse link
G ADCY8 adenylate cyclase 8 located_in ISO PMID:19158400 UniProt PMID:19158400 RGD:13800545 NCBI chr 4:9,645,398...9,867,065
Ensembl chr 4:9,645,659...9,866,550 		JBrowse link
G AMN amnion associated transmembrane protein located_in IEA UniProt GO_REF:0000043
G AP1S1 adaptor related protein complex 1 subunit sigma 1 located_in IEA UniProt GO_REF:0000044 NCBI chr 3:8,880,993...8,887,806
Ensembl chr 3:8,881,107...8,887,566 		JBrowse link
G AP1S2 adaptor related protein complex 1 subunit sigma 2 located_in IEA UniProt GO_REF:0000044 NCBI chr  X:12,367,785...12,397,672
Ensembl chr  X:12,367,795...12,397,677 		JBrowse link
G AP1S3 adaptor related protein complex 1 subunit sigma 3 located_in IEA UniProt GO_REF:0000044 NCBI chr15:125,561,513...125,637,215
Ensembl chr15:125,561,513...125,636,436 		JBrowse link
G AP2A1 adaptor related protein complex 2 subunit alpha 1 located_in IEA UniProt GO_REF:0000043 NCBI chr 6:54,786,537...54,823,906
Ensembl chr 6:54,786,511...54,823,904 		JBrowse link
G AP2A2 adaptor related protein complex 2 subunit alpha 2 located_in IEA UniProt GO_REF:0000043 NCBI chr 2:580,169...628,098
Ensembl chr 2:580,182...628,087 		JBrowse link
G AP2M1 adaptor related protein complex 2 subunit mu 1 located_in IEA UniProt
Ensembl		 GO_REF:0000043 GO_REF:0000107 NCBI chr13:122,094,375...122,103,408
Ensembl chr13:122,094,437...122,104,802 		JBrowse link
G AP2S1 adaptor related protein complex 2 subunit sigma 1 located_in IEA UniProt GO_REF:0000043 NCBI chr 6:52,695,640...52,703,263
Ensembl chr 6:52,695,640...52,703,278 		JBrowse link
G APP amyloid beta precursor protein located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,435,094...189,716,056 		JBrowse link
G ARRB1 arrestin beta 1 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr 9:9,516,944...9,597,446
Ensembl chr 9:9,516,947...9,597,976 		JBrowse link
G ATAT1 alpha tubulin acetyltransferase 1 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr 7:23,173,138...23,185,463
Ensembl chr 7:23,173,438...23,185,451 		JBrowse link
G BCL2L1 BCL2 like 1 located_in ISO PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 located_in
is_active_in		 IEA
ISO		 (PMID:16923969) Ensembl
MGI		 PMID:16923969 GO_REF:0000107 NCBI chr15:105,971,577...106,132,496
Ensembl chr15:105,970,428...106,135,730 		JBrowse link
G CCDC32 coiled-coil domain containing 32 located_in
part_of		 IEA
ISO		 (PMID:33859415) Ensembl
UniProt		 PMID:33859415 GO_REF:0000107 NCBI chr 1:130,753,107...130,764,747
Ensembl chr 1:130,753,186...130,764,746 		JBrowse link
G CDHR5 cadherin related family member 5 ISO RGD PMID:10801787 RGD:633361 NCBI chr 2:376,449...382,713
Ensembl chr 2:375,726...382,719 		JBrowse link
G CLTA clathrin light chain A located_in ISO
IEA		 RGD
UniProt		 PMID:14985443 GO_REF:0000043 RGD:2301373 NCBI chr 1:236,971,317...236,993,291
Ensembl chr 1:236,971,505...237,001,731 		JBrowse link
G CLTB clathrin light chain B located_in IEA UniProt GO_REF:0000043 NCBI chr 2:81,488,191...81,498,623
Ensembl chr 2:81,488,092...81,495,014 		JBrowse link
G CLTB clathrin light chain B located_in IEA UniProt GO_REF:0000043 NCBI chr 2:81,464,887...81,484,712
Ensembl chr 2:81,464,917...81,485,419 		JBrowse link
G CLTC clathrin heavy chain located_in IEA UniProt GO_REF:0000043 NCBI chr12:35,848,894...35,926,028
Ensembl chr12:35,848,540...35,926,015 		JBrowse link
G CTTN cortactin located_in ISO PMID:19995918 UniProt PMID:19995918 RGD:10047197 NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,103...3,060,813 		JBrowse link
G CUBN cubilin located_in IEA UniProt GO_REF:0000043 NCBI chr10:43,102,931...43,414,692
Ensembl chr10:43,102,946...43,414,758 		JBrowse link
G DAB2 DAB adaptor protein 2 located_in
is_active_in		 IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,590,645...24,646,122 		JBrowse link
G DGKD diacylglycerol kinase delta located_in IEA Ensembl GO_REF:0000107 NCBI chr15:133,749,349...133,867,804
Ensembl chr15:133,749,345...133,867,801 		JBrowse link
G DNM1 dynamin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:268,653,045...268,702,233
Ensembl chr 1:268,653,070...268,702,222 		JBrowse link
G DNM2 dynamin 2 located_in ISO (PMID:26437238)
PMID:19995918		 RGD
MGI
UniProt		 PMID:9725914 PMID:19995918 PMID:26437238 RGD:10047197 RGD:9685132 NCBI chr 2:69,474,011...69,574,427
Ensembl chr 2:69,474,031...69,574,424 		JBrowse link
G EPN3 epsin 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr12:26,812,653...26,825,485
Ensembl chr12:26,815,461...26,825,482 		JBrowse link
G EPS15 epidermal growth factor receptor pathway substrate 15 located_in ISO (PMID:20427320) MGI PMID:20427320 NCBI chr 6:160,653,818...160,792,516
Ensembl chr 6:160,653,917...160,801,288 		JBrowse link
G FCHO1 FCH and mu domain containing endocytic adaptor 1 located_in
is_active_in		 IEA
IBA		 Ensembl
UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000043 GO_REF:0000044 GO_REF:0000107 NCBI chr 2:59,958,122...59,990,511
Ensembl chr 2:59,958,134...59,990,490 		JBrowse link
G FCHO2 FCH and mu domain containing endocytic adaptor 2 located_in
is_active_in		 IEA
IBA		 UniProt
GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000043 GO_REF:0000044 GO_REF:0000107 NCBI chr 2:82,101,283...82,248,410
Ensembl chr 2:82,101,343...82,248,821 		JBrowse link
G FCHSD2 FCH and double SH3 domains 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:7,366,516...7,619,960
Ensembl chr 9:7,366,523...7,608,469 		JBrowse link
G FGD4 FYVE, RhoGEF and PH domain containing 4 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr 5:41,571,054...41,636,058
Ensembl chr 5:41,570,282...41,636,028 		JBrowse link
G GAS7 growth arrest specific 7 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr12:54,752,436...54,974,535
Ensembl chr12:54,752,507...54,973,515 		JBrowse link
G HIP1R huntingtin interacting protein 1 related located_in IEA Ensembl GO_REF:0000107 NCBI chr14:29,996,388...30,024,343
Ensembl chr14:29,993,655...30,024,216 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr15:101,360,355...101,373,498
Ensembl chr15:101,360,094...101,373,526 		JBrowse link
G INPP5F inositol polyphosphate-5-phosphatase F located_in IEA Ensembl GO_REF:0000107 NCBI chr14:129,577,594...129,671,541
Ensembl chr14:129,577,567...129,669,875 		JBrowse link
G ITSN1 intersectin 1 located_in ISO
IEA		 RGD
Ensembl		 PMID:19258322 GO_REF:0000107 RGD:13461864 NCBI chr13:197,301,515...197,492,537
Ensembl chr13:197,249,061...197,481,245 		JBrowse link
G LDLR low density lipoprotein receptor located_in IEA UniProt
Ensembl		 GO_REF:0000043 GO_REF:0000044 GO_REF:0000107 NCBI chr 2:69,828,348...69,864,823
Ensembl chr 2:69,828,332...69,864,827 		JBrowse link
G LRP10 LDL receptor related protein 10 located_in IEA UniProt GO_REF:0000043 NCBI chr 7:76,149,304...76,159,397
Ensembl chr 7:76,149,307...76,158,891 		JBrowse link
G LRP2 LDL receptor related protein 2 located_in IEA Ensembl
UniProt		 GO_REF:0000043 GO_REF:0000044 GO_REF:0000107 NCBI chr15:75,565,299...75,754,604
Ensembl chr15:75,565,303...75,716,694 		JBrowse link
G LRP3 LDL receptor related protein 3 located_in IEA UniProt GO_REF:0000043 NCBI chr 6:42,988,446...43,001,424
Ensembl chr 6:42,988,482...43,001,421 		JBrowse link
G MYO6 myosin VI NOT|located_in IDA (PMID:12857860) UniProt PMID:12857860 NCBI chr 1:89,992,860...90,137,767
Ensembl chr 1:89,992,866...90,137,734 		JBrowse link
G NECAP1 NECAP endocytosis associated 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:63,157,115...63,188,983
Ensembl chr 5:63,122,325...63,188,981 		JBrowse link
G NECAP1 NECAP endocytosis associated 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:63,122,280...63,135,550
Ensembl chr 5:63,122,335...63,139,664 		JBrowse link
G NUMB NUMB endocytic adaptor protein located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:96,624,270...96,798,690
Ensembl chr 7:96,624,274...96,799,288 		JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein located_in
is_active_in		 IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:19,835,934...19,947,239
Ensembl chr 9:19,835,938...20,123,566 		JBrowse link
G PPP1R21 protein phosphatase 1 regulatory subunit 21 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:92,091,763...92,145,386
Ensembl chr 3:92,092,635...92,109,713 		JBrowse link
G RAB35 RAB35, member RAS oncogene family located_in IEA Ensembl GO_REF:0000107 NCBI chr14:40,124,318...40,141,261
Ensembl chr14:40,124,326...40,141,668 		JBrowse link
G REPS1 RALBP1 associated Eps domain containing 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:25,481,283...25,565,284
Ensembl chr 1:25,481,343...25,565,277 		JBrowse link
G SELE selectin E located_in ISO (PMID:18029551) BHF-UCL PMID:18029551 NCBI chr 4:81,289,061...81,299,657 JBrowse link
G SGIP1 SH3GL interacting endocytic adaptor 1 located_in IEA UniProt
Ensembl		 GO_REF:0000043 GO_REF:0000044 GO_REF:0000107 NCBI chr 6:145,815,658...146,051,621
Ensembl chr 6:145,822,269...146,052,526 		JBrowse link
G SH3BP4 SH3 domain binding protein 4 located_in IEA UniProt GO_REF:0000043 GO_REF:0000044 NCBI chr15:135,003,501...135,094,801
Ensembl chr15:135,003,511...135,094,797 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 ISO RGD PMID:1881917 RGD:2306204 NCBI chr12:52,628,746...52,634,965
Ensembl chr12:52,628,450...52,634,967 		JBrowse link
G SNAP91 synaptosome associated protein 91 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 1:82,540,998...82,698,652
Ensembl chr 1:82,541,018...82,698,633 		JBrowse link
G SNX9 sorting nexin 9 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:9,130,360...9,239,023
Ensembl chr 1:9,130,338...9,239,029 		JBrowse link
G SORT1 sortilin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 4:110,721,110...110,791,406
Ensembl chr 4:110,720,947...110,789,070 		JBrowse link
G SPHK1 sphingosine kinase 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr12:5,114,946...5,122,580
Ensembl chr12:5,114,947...5,120,083 		JBrowse link
G TF transferrin located_in IEA Ensembl GO_REF:0000107 NCBI chr13:74,930,655...74,970,599
Ensembl chr13:74,930,655...74,972,763 		JBrowse link
G TFAP2A transcription factor AP-2 alpha located_in ISO (PMID:26437238) MGI PMID:26437238 NCBI chr 7:7,221,654...7,244,626
Ensembl chr 7:7,221,656...7,244,612 		JBrowse link
G TFRC transferrin receptor located_in IEA Ensembl GO_REF:0000107 NCBI chr13:133,976,765...133,997,554
Ensembl chr13:133,970,985...134,000,276 		JBrowse link
G TNK2 tyrosine kinase non receptor 2 located_in ISO (PMID:21169560) UniProt PMID:21169560 NCBI chr13:134,082,266...134,124,826
Ensembl chr13:134,101,377...134,124,824 		JBrowse link
AP-2 adaptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP2A1 adaptor related protein complex 2 subunit alpha 1 part_of IEA
IBA		 InterPro
GO_Central
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 6:54,786,537...54,823,906
Ensembl chr 6:54,786,511...54,823,904 		JBrowse link
G AP2A2 adaptor related protein complex 2 subunit alpha 2 part_of IEA
IBA		 InterPro
GO_Central
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 2:580,169...628,098
Ensembl chr 2:580,182...628,087 		JBrowse link
G AP2B1 adaptor related protein complex 2 subunit beta 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr12:39,803,105...39,940,801
Ensembl chr12:39,800,972...39,932,643 		JBrowse link
G AP2M1 adaptor related protein complex 2 subunit mu 1 part_of IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr13:122,094,375...122,103,408
Ensembl chr13:122,094,437...122,104,802 		JBrowse link
G AP2S1 adaptor related protein complex 2 subunit sigma 1 part_of ISO
IEA		 RGD
Ensembl
InterPro		 PMID:7593184 GO_REF:0000002 GO_REF:0000107 RGD:2306270 NCBI chr 6:52,695,640...52,703,263
Ensembl chr 6:52,695,640...52,703,278 		JBrowse link
G EPS15 epidermal growth factor receptor pathway substrate 15 part_of ISO (PMID:17626015) UniProt PMID:17626015 NCBI chr 6:160,653,818...160,792,516
Ensembl chr 6:160,653,917...160,801,288 		JBrowse link
G KIAA1107 KIAA1107 ortholog located_in ISO PMID:29262337 UniProt PMID:29262337 RGD:13601995 NCBI chr 4:124,859,271...124,950,420
Ensembl chr 4:124,859,279...124,950,271 		JBrowse link
G PPP1R21 protein phosphatase 1 regulatory subunit 21 part_of IBA GO_Central GO_REF:0000033 NCBI chr 3:92,091,763...92,145,386
Ensembl chr 3:92,092,635...92,109,713 		JBrowse link
G SGIP1 SH3GL interacting endocytic adaptor 1 part_of ISO (PMID:17626015) UniProt PMID:17626015 NCBI chr 6:145,815,658...146,051,621
Ensembl chr 6:145,822,269...146,052,526 		JBrowse link
G SLC18A3 solute carrier family 18 member A3 part_of ISO
IBA		 RGD
GO_Central		 PMID:14724281 GO_REF:0000033 RGD:2317430 NCBI chr14:90,113,534...90,115,813
Ensembl chr14:90,113,844...90,115,430 		JBrowse link
G STON2 stonin 2 part_of IBA GO_Central GO_REF:0000033 NCBI chr 7:104,034,913...104,189,735
Ensembl chr 7:104,039,493...104,189,701 		JBrowse link
G TBC1D5 TBC1 domain family member 5 part_of
located_in		 IEA
ISO		 (PMID:24603492) Ensembl
UniProt		 PMID:24603492 GO_REF:0000107 NCBI chr13:4,191,544...4,738,448
Ensembl chr13:4,201,255...4,633,312 		JBrowse link
clathrin coat of coated pit term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLTA clathrin light chain A part_of IEA InterPro GO_REF:0000002 NCBI chr 1:236,971,317...236,993,291
Ensembl chr 1:236,971,505...237,001,731 		JBrowse link
G CLTB clathrin light chain B part_of IEA InterPro GO_REF:0000002 NCBI chr 2:81,488,191...81,498,623
Ensembl chr 2:81,488,092...81,495,014 		JBrowse link
G CLTB clathrin light chain B part_of IEA InterPro GO_REF:0000002 NCBI chr 2:81,464,887...81,484,712
Ensembl chr 2:81,464,917...81,485,419 		JBrowse link
G CLTC clathrin heavy chain part_of IEA InterPro GO_REF:0000002 NCBI chr12:35,848,894...35,926,028
Ensembl chr12:35,848,540...35,926,015 		JBrowse link
G DAB2 DAB adaptor protein 2 part_of ISO (PMID:11247302) UniProt PMID:11247302 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,590,645...24,646,122 		JBrowse link
G EPS15 epidermal growth factor receptor pathway substrate 15 part_of IBA GO_Central GO_REF:0000033 NCBI chr 6:160,653,818...160,792,516
Ensembl chr 6:160,653,917...160,801,288 		JBrowse link
G EPS15L1 epidermal growth factor receptor pathway substrate 15 like 1 part_of IBA GO_Central GO_REF:0000033 NCBI chr 2:61,139,051...61,243,127
Ensembl chr 2:61,139,045...61,243,118 		JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein part_of IEA Ensembl GO_REF:0000107 NCBI chr 9:19,835,934...19,947,239
Ensembl chr 9:19,835,938...20,123,566 		JBrowse link
G SYNJ1 synaptojanin 1 part_of ISO PMID:9428629 ParkinsonsUK-UCL PMID:9428629 RGD:11059574 NCBI chr13:196,230,101...196,330,512
Ensembl chr13:196,230,104...196,330,384 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19753
    cellular anatomical structure 19508
      membrane 9909
        clathrin-coated pit 70
          clathrin coat of coated pit + 20
paths to the root