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ONTOLOGY REPORT - ANNOTATIONS

Term:actin filament
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Accession:GO:0005884 term browser browse the term
Definition:A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
Synonyms:exact_synonym: microfilament
 xref: FMA:63850;   NIF_Subcellular:sao1588493326;   Wikipedia:Actin


show annotations for term's descendants           Sort by:
actin filament term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 located_in ISO (PMID:15572692) RGD PMID:15572692 NCBI chr 9:61,827,186...61,905,703
Ensembl chr 9:61,827,139...61,905,699 		JBrowse link
G Ackr2 atypical chemokine receptor 2 located_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23633677)		 UniProt
Ensembl
RGD		 PMID:23633677 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:121,559,563...121,573,633
Ensembl chr 8:121,561,211...121,573,582 		JBrowse link
G Acta1 actin, alpha 1, skeletal muscle located_in
is_active_in		 ISO
ISS
IBA		 (PMID:12849983)
GO_REF:0000024
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:12849983 GO_REF:0000024 GO_REF:0000033 NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742 		JBrowse link
G Actb actin, beta is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Actbl2 actin, beta-like 2 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:42,858,020...42,860,767
Ensembl chr 2:42,858,020...42,860,767 		JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 located_in
is_active_in		 ISO
IBA		 (PMID:16611632), (PMID:19799913)
GO_REF:0000033		 RGD
GO_Central		 PMID:16611632 PMID:19799913 GO_REF:0000033 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523 		JBrowse link
G Actg1 actin, gamma 1 located_in
is_active_in		 ISO
IBA		 (PMID:28493397)
GO_REF:0000033		 RGD
GO_Central		 PMID:28493397 GO_REF:0000033 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232 		JBrowse link
G Actg1l1 actin, gamma 1 like 1 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:72,977,767...72,979,691
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232 		JBrowse link
G Actl9 actin-like 9 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:14,234,504...14,235,881
Ensembl chr 7:14,234,504...14,235,881 		JBrowse link
G Actl9b actin-like 9b is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:63,830,481...63,831,818
Ensembl chr 1:63,830,223...63,831,822 		JBrowse link
G Actn1 actinin, alpha 1 located_in IEA
ISO		 GO_REF:0000107
(PMID:23434115), (PMID:24069336)		 Ensembl
RGD		 PMID:23434115 PMID:24069336 GO_REF:0000107 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251 		JBrowse link
G Actr3 actin related protein 3 located_in IDA RGD PMID:10209028 RGD:2306208 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Afap1 actin filament associated protein 1 IDA RGD PMID:12114187 RGD:625602 NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263 		JBrowse link
G Aif1 allograft inflammatory factor 1 located_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:14756805)
GO_REF:0000033
(PMID:18699778)		 UniProt
RGD
GO_Central		 PMID:14756805 PMID:18699778 GO_REF:0000024 GO_REF:0000033 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Aif1l allograft inflammatory factor 1-like located_in ISO
IBA		 (PMID:18699778)
GO_REF:0000033		 RGD
GO_Central		 PMID:18699778 GO_REF:0000033 NCBI chr 3:15,229,476...15,254,033
Ensembl chr 3:15,229,524...15,254,023 		JBrowse link
G Akap13 A-kinase anchoring protein 13 located_in ISO (MGI:5308772|PMID:20139090) RGD PMID:20139090 MGI:5308772 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646 		JBrowse link
G Amot angiomotin located_in ISO (PMID:11257124) RGD PMID:11257124 NCBI chr  X:108,982,399...109,041,265
Ensembl chr  X:108,984,022...109,041,272 		JBrowse link
G Anxa1 annexin A1 located_in IEA
ISO		 GO_REF:0000107
(PMID:22773844)		 Ensembl
RGD		 PMID:22773844 GO_REF:0000107 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 located_in ISO (PMID:11691822) RGD PMID:11691822 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310 		JBrowse link
G Avil advillin located_in ISS
ISO		 GO_REF:0000024
(PMID:29058690)		 UniProt
RGD		 PMID:29058690 GO_REF:0000024 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071 		JBrowse link
G Cald1 caldesmon 1 IDA RGD PMID:3384851 RGD:2303065 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932 		JBrowse link
G Cd2ap CD2-associated protein is_active_in ISO (PMID:17606992) RGD PMID:17606992 NCBI chr 9:18,086,744...18,182,744
Ensembl chr 9:18,086,984...18,182,199 		JBrowse link
G Cnn3 calponin 3 TAS RGD PMID:12564930 RGD:727577 NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104 		JBrowse link
G Cobl cordon-bleu WH2 repeat protein located_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(MGI:3765263|PMID:17956734)		 Ensembl
GO_Central
RGD		 PMID:17956734 GO_REF:0000033 GO_REF:0000107 MGI:3765263 NCBI chr14:86,828,137...87,060,682
Ensembl chr14:86,828,139...87,060,800 		JBrowse link
G Coro1a coronin 1A located_in ISO (PMID:15800061) RGD PMID:15800061 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534 		JBrowse link
G Coro1b coronin 1B located_in ISO
IEA		 (PMID:18775315)
GO_REF:0000107		 RGD
Ensembl		 PMID:18775315 GO_REF:0000107 NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416 		JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 located_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689 		JBrowse link
G Cttn cortactin located_in IEA
IBA
ISO
IMP
ISS		 GO_REF:0000107
GO_REF:0000033
(PMID:12151401)
PMID:18768925
GO_REF:0000024		 Ensembl
GO_Central
RGD
UniProt		 PMID:12151401 PMID:18768925 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:10047281 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Dapk3 death-associated protein kinase 3 IDA RGD PMID:10602480 RGD:8554171 NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558 		JBrowse link
G Dbn1 drebrin 1 located_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:10234022 GO_REF:0000033, RGD:10395287 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Dbnl drebrin-like located_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:80,666,115...80,681,155
Ensembl chr14:80,666,124...80,681,155 		JBrowse link
G Diaph1 diaphanous-related formin 1 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:29,669,659...29,769,070
Ensembl chr18:29,669,659...29,769,172 		JBrowse link
G Diaph3 diaphanous-related formin 3 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein located_in IDA RGD PMID:15506980 RGD:1624304 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G Dmtn dematin actin binding protein located_in ISO (PMID:22927433) RGD PMID:22927433 NCBI chr15:45,677,974...45,702,261
Ensembl chr15:45,677,977...45,705,601 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 located_in ISO (PMID:17588722) RGD PMID:17588722 NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161 		JBrowse link
G Dstl1 dystonin like 1 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:107,838,089...107,847,304
Ensembl chr 7:107,838,080...107,845,981 		JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A located_in ISO UniProtKB:P60709 (PMID:24327345) RGD PMID:24327345 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420 		JBrowse link
G Ezr ezrin located_in ISO
IEA
ISS		 (PMID:11598191)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11598191 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Fhdc1 FH2 domain containing 1 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:169,790,917...169,829,580
Ensembl chr 2:169,790,947...169,827,896 		JBrowse link
G Flna filamin A located_in IDA RGD PMID:15661894 PMID:22872576 RGD:2312435, RGD:7207404 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052 		JBrowse link
G Fmn1 formin 1 located_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:100,101,103...100,485,652
Ensembl chr 3:100,134,549...100,479,220 		JBrowse link
G Fmn2 formin 2 located_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:86,454,256...86,771,437
Ensembl chr13:86,453,926...86,771,411 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase located_in IEA
ISO		 GO_REF:0000107
(PMID:17623777)		 Ensembl
RGD		 PMID:17623777 GO_REF:0000107 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gas2 growth arrest-specific 2 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619 		JBrowse link
G Gas2l1 growth arrest-specific 2 like 1 located_in
is_active_in		 ISO
IBA		 (PMID:24706950)
GO_REF:0000033		 RGD
GO_Central		 PMID:24706950 GO_REF:0000033 NCBI chr14:79,955,350...79,961,830
Ensembl chr14:79,950,555...79,961,438 		JBrowse link
G Gas2l2 growth arrest-specific 2 like 2 located_in
is_active_in		 ISO
IBA		 (PMID:24706950)
GO_REF:0000033		 RGD
GO_Central		 PMID:24706950 GO_REF:0000033 NCBI chr10:68,222,475...68,229,877
Ensembl chr10:68,222,475...68,229,881 		JBrowse link
G Gas2l3 growth arrest-specific 2 like 3 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:23,803,578...23,836,816
Ensembl chr 7:23,806,310...23,836,411 		JBrowse link
G Gas7 growth arrest specific 7 is_active_in
located_in		 IBA
ISO		 GO_REF:0000033
(PMID:11795944)		 GO_Central
RGD		 PMID:11795944 GO_REF:0000033 NCBI chr10:52,152,718...52,383,283
Ensembl chr10:52,152,493...52,383,276 		JBrowse link
G Gck glucokinase located_in IDA in primary rat hepatocytes and transfected COS-7 cells RGD PMID:9109397 RGD:2301953 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Gdpd2 glycerophosphodiester phosphodiesterase domain containing 2 located_in ISO (PMID:12933806) RGD PMID:12933806 NCBI chr  X:65,826,273...65,835,361
Ensembl chr  X:65,826,574...65,835,361 		JBrowse link
G Gjb6 gap junction protein, beta 6 located_in ISO (PMID:19285977) RGD PMID:19285977 NCBI chr15:31,284,561...31,294,552
Ensembl chr15:31,284,419...31,294,582 		JBrowse link
G Gng12 G protein subunit gamma 12 located_in IDA RGD PMID:9492299 RGD:2314449 NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712 		JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase located_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:15998323)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:15998323 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 located_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D IDA RGD PMID:15661894 RGD:2312435 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 located_in IEA
ISO		 GO_REF:0000107
(MGI:5619488|PMID:14764898)		 Ensembl
RGD		 PMID:14764898 GO_REF:0000107 MGI:5619488 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 located_in
is_active_in		 ISO
IBA		 (PMID:16636079)
(PMID:14756805)
GO_REF:0000033		 RGD
GO_Central		 PMID:14756805 PMID:16636079 GO_REF:0000033 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680 		JBrowse link
G Lmod1 leiomodin 1 located_in IDA PMID:10520227 UniProt PMID:10520227 RGD:11344950 NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900 		JBrowse link
G Lmod2 leiomodin 2 located_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:26370058)		 UniProt
Ensembl
RGD		 PMID:26370058 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120 		JBrowse link
G LOC120098222 uncharacterized LOC120098222 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:23,787,211...23,806,982 JBrowse link
G Mark2 microtubule affinity regulating kinase 2 located_in ISO
IEA
ISS		 (PMID:23902687)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:23902687 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:204,461,029...204,526,247
Ensembl chr 1:204,461,030...204,525,652 		JBrowse link
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 is_active_in ISO (PMID:33393173) RGD PMID:33393173 NCBI chr20:44,974,137...44,986,089
Ensembl chr20:44,974,138...44,986,089 		JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 is_active_in
located_in		 ISO
IEA		 (PMID:29343822)
GO_REF:0000107		 RGD
Ensembl		 PMID:29343822 GO_REF:0000107 NCBI chr 1:166,345,853...166,530,575
Ensembl chr 1:166,345,859...166,471,719
Ensembl chr 1:166,345,859...166,471,719 		JBrowse link
G Misp mitotic spindle positioning located_in ISO (PMID:23574715) RGD PMID:23574715 NCBI chr 7:9,870,390...9,886,541
Ensembl chr 7:9,870,444...9,886,541 		JBrowse link
G Myh9 myosin, heavy chain 9 IDA RGD PMID:21598299 RGD:12798522 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Myo1b myosin Ib located_in ISO (PMID:16219689) RGD PMID:16219689 NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798 		JBrowse link
G Myo5a myosin VA located_in IEA
ISO		 GO_REF:0000107
(PMID:24006491)		 Ensembl
RGD		 PMID:24006491 GO_REF:0000107 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Myo6 myosin VI located_in ISO (PMID:12857860) RGD PMID:12857860 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292 		JBrowse link
G Myo9a myosin IXA is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:60,149,234...60,352,330
Ensembl chr 8:60,149,234...60,350,514 		JBrowse link
G Myo9b myosin IXb is_active_in
located_in		 IDA
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:16338935), (PMID:16616011), (PMID:8907710)		 GO_Central
Ensembl
RGD		 PMID:8907710 PMID:16338935 PMID:16616011 PMID:9348541 GO_REF:0000033 GO_REF:0000107, RGD:1581711 NCBI chr16:17,945,379...18,030,114
Ensembl chr16:17,945,448...18,030,126 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 located_in ISO (PMID:9395435) RGD PMID:9395435 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Palld palladin, cytoskeletal associated protein located_in ISO
IEA		 (PMID:11598191)
GO_REF:0000107		 RGD
Ensembl		 PMID:11598191 GO_REF:0000107 NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337 		JBrowse link
G Pawr pro-apoptotic WT1 regulator located_in IDA PMID:16229834 RGD
UniProt		 PMID:15817164 PMID:16229834 RGD:9835355, RGD:8554822 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pls1 plastin 1 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195 		JBrowse link
G Pls3 plastin 3 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891 		JBrowse link
G Pof1b POF1B, actin binding protein located_in
is_active_in		 ISO
IBA		 (PMID:16773570)
GO_REF:0000033		 RGD
GO_Central		 PMID:16773570 GO_REF:0000033 NCBI chr  X:77,683,128...77,749,827
Ensembl chr  X:77,683,128...77,749,688 		JBrowse link
G Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:56,499,287...56,538,593
Ensembl chr 8:56,499,590...56,538,580 		JBrowse link
G Pstpip2 proline-serine-threonine phosphatase-interacting protein 2 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:71,310,387...71,396,752
Ensembl chr18:71,311,020...71,395,709 		JBrowse link
G Ptges3 prostaglandin E synthase 3 IDA RGD PMID:8864660 RGD:5688126 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084 		JBrowse link
G Rac1 Rac family small GTPase 1 located_in IEA
ISO		 GO_REF:0000107
(PMID:19625648)		 Ensembl
RGD		 PMID:19625648 GO_REF:0000107 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rac2 Rac family small GTPase 2 located_in ISO (PMID:19625648) RGD PMID:19625648 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720 		JBrowse link
G Rhoq ras homolog family member Q located_in ISO (PMID:10445846) RGD PMID:10445846 NCBI chr 6:7,613,632...7,652,047 JBrowse link
G Sh2b2 SH2B adaptor protein 2 located_in ISO (PMID:14993264) RGD PMID:14993264 NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844 		JBrowse link
G Shroom4 shroom family member 4 located_in ISO (PMID:16249884), (PMID:16684770) RGD PMID:16249884 PMID:16684770 NCBI chr  X:15,869,065...16,076,850
Ensembl chr  X:15,869,065...16,076,869 		JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 located_in ISO (MGI:2181223|PMID:11807096) RGD PMID:11807096 MGI:2181223 NCBI chr 1:82,650,750...82,738,345
Ensembl chr 1:82,650,751...82,737,228 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase located_in ISO (PMID:17623777) RGD PMID:17623777 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tek TEK receptor tyrosine kinase located_in ISO (PMID:18425119) RGD PMID:18425119 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tfpt TCF3 fusion partner located_in IDA PMID:16229834 UniProt PMID:16229834 RGD:8554822 NCBI chr 1:65,587,633...65,597,407
Ensembl chr 1:65,582,359...65,611,689 		JBrowse link
G Tmod1 tropomodulin 1 located_in ISO
IEA
ISS		 (PMID:26370058)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26370058 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:60,316,445...60,393,957
Ensembl chr 5:60,338,512...60,393,956 		JBrowse link
G Tpm1 tropomyosin 1 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802 		JBrowse link
G Tpm2 tropomyosin 2 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:57,770,919...57,780,278
Ensembl chr 5:57,770,864...57,779,992 		JBrowse link
G Tpm3 tropomyosin 3 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013 		JBrowse link
G Tpm4 tropomyosin 4 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984 		JBrowse link
G Tsc1 TSC complex subunit 1 located_in IEA
ISO		 GO_REF:0000107
(PMID:10806479)		 Ensembl
RGD		 PMID:10806479 GO_REF:0000107 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:125,715,938...125,727,834
Ensembl chr 7:125,716,015...125,727,894 		JBrowse link
G Twf2 twinfilin actin-binding protein 2 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298 		JBrowse link
G Vcl vinculin located_in IDA RGD PMID:15506980 RGD:1624304 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606 		JBrowse link
G Vps11 VPS11 core subunit of CORVET and HOPS complexes located_in ISO (PMID:14668490) RGD PMID:14668490 NCBI chr 8:44,684,129...44,698,568
Ensembl chr 8:44,684,127...44,698,568 		JBrowse link
G Vps16 VPS16 core subunit of CORVET and HOPS complexes located_in ISO (PMID:14668490) RGD PMID:14668490 NCBI chr 3:117,622,534...117,644,041
Ensembl chr 3:117,622,542...117,646,441 		JBrowse link
G Vps18 VPS18 core subunit of CORVET and HOPS complexes located_in ISO (PMID:14668490) RGD PMID:14668490 NCBI chr 3:106,279,444...106,290,298
Ensembl chr 3:106,279,425...106,291,964 		JBrowse link
G Was WASP actin nucleation promoting factor located_in ISO (PMID:8625410) RGD PMID:8625410 NCBI chr  X:14,405,105...14,413,850
Ensembl chr  X:14,405,124...14,413,849 		JBrowse link
G Whrn whirlin located_in IEA
ISO		 GO_REF:0000107
(PMID:12833159)		 Ensembl
RGD		 PMID:12833159 GO_REF:0000107 NCBI chr 5:76,828,308...76,911,945
Ensembl chr 5:76,828,301...76,912,223 		JBrowse link
G Wipf1 WAS/WASL interacting protein family, member 1 located_in IDA
ISO
IEA		 (PMID:22966049)
GO_REF:0000107		 RGD
Ensembl		 PMID:22966049 PMID:11687573 GO_REF:0000107, RGD:634538 NCBI chr 3:58,314,521...58,416,668
Ensembl chr 3:58,314,542...58,372,742 		JBrowse link
G Yes1 YES proto-oncogene 1, Src family tyrosine kinase located_in ISO (PMID:17623777) RGD PMID:17623777 NCBI chr 9:113,200,256...113,275,942
Ensembl chr 9:113,200,256...113,299,837 		JBrowse link
actin filament branch point term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc2 actin related protein 2/3 complex, subunit 2 IDA RGD PMID:18256280 RGD:2306202 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471 		JBrowse link
filamentous actin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actg1 actin, gamma 1 part_of IEA
ISO		 GO_REF:0000107
(PMID:18796539)		 Ensembl
RGD		 PMID:18796539 GO_REF:0000107 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232 		JBrowse link
G Actg1l1 actin, gamma 1 like 1 part_of IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:72,977,767...72,979,691
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 located_in ISO (PMID:25753423) RGD PMID:25753423 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310 		JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 IDA RGD PMID:10797548 RGD:11049163 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471 		JBrowse link
G Arpc3 actin related protein 2/3 complex, subunit 3 IDA RGD PMID:10797548 RGD:11049163 NCBI chr12:34,172,780...34,186,651
Ensembl chr12:34,172,780...34,186,651 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 part_of ISO (PMID:19116644) RGD PMID:19116644 NCBI chr 3:109,816,397...109,826,528
Ensembl chr 3:109,816,366...109,828,308 		JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 part_of ISO (MGI:3588909|PMID:16054028) RGD PMID:16054028 MGI:3588909 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326 		JBrowse link
G Cd2ap CD2-associated protein part_of ISO
IEA		 (PMID:10339567)
GO_REF:0000107		 RGD
Ensembl		 PMID:10339567 GO_REF:0000107 NCBI chr 9:18,086,744...18,182,744
Ensembl chr 9:18,086,984...18,182,199 		JBrowse link
G Diaph3 diaphanous-related formin 3 part_of IEA
ISO		 GO_REF:0000107
(PMID:18835565)		 Ensembl
RGD		 PMID:18835565 GO_REF:0000107 NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975 		JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 part_of IDA PMID:16181627 UniProt PMID:16181627 RGD:8553533 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157 		JBrowse link
G Dusp22 dual specificity phosphatase 22 part_of ISO (PMID:20018849) RGD PMID:20018849 NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321 		JBrowse link
G Espn espin part_of IDA PMID:8799813 UniProt PMID:8799813 RGD:632658 NCBI chr 5:162,626,560...162,660,439
Ensembl chr 5:162,626,560...162,660,256 		JBrowse link
G Jam3 junctional adhesion molecule 3 part_of ISO
IEA		 (PMID:19060272)
GO_REF:0000107		 RGD
Ensembl		 PMID:19060272 GO_REF:0000107 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355 		JBrowse link
G Kptn kaptin (actin binding protein) located_in ISO (PMID:24239382) RGD PMID:24239382 NCBI chr 1:76,808,737...76,809,531 JBrowse link
G Ldb3 LIM domain binding 3 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:9,855,768...9,920,108
Ensembl chr16:9,855,927...9,918,532 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 part_of ISO (PMID:25224220) RGD PMID:25224220 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Myo18b myosin XVIIIb part_of ISO (PMID:18761673) RGD PMID:18761673 NCBI chr12:43,747,003...43,953,694
Ensembl chr12:43,747,010...43,953,695 		JBrowse link
G Myo1a myosin IA part_of ISS
ISO
IEA		 GO_REF:0000024
(PMID:9858156)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:9858156 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:63,542,988...63,557,944
Ensembl chr 7:63,542,988...63,557,944 		JBrowse link
G Myo1c myosin 1C part_of ISO
IEA		 (PMID:9858156)
GO_REF:0000107		 RGD
Ensembl		 PMID:9858156 GO_REF:0000107 NCBI chr10:60,498,372...60,520,752
Ensembl chr10:60,498,280...60,520,752 		JBrowse link
G Myo1f myosin IF part_of ISO (PMID:17023661) RGD PMID:17023661 NCBI chr 7:14,363,340...14,413,911
Ensembl chr 7:14,363,350...14,413,911 		JBrowse link
G Myo3a myosin IIIA part_of ISO (PMID:12672820) RGD PMID:12672820 NCBI chr17:84,543,465...84,759,562
Ensembl chr17:84,543,552...84,759,042 		JBrowse link
G Myo6 myosin VI part_of ISO (PMID:9852149)
(PMID:10519557)		 RGD PMID:9852149 PMID:10519557 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292 		JBrowse link
G Nckap1 NCK-associated protein 1 part_of ISO (MGI:5897521|PMID:27927633) RGD PMID:27927633 MGI:5897521 NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217 		JBrowse link
G Pdlim1 PDZ and LIM domain 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076 		JBrowse link
G Pdlim2 PDZ and LIM domain 2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242 		JBrowse link
G Pdlim3 PDZ and LIM domain 3 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:46,352,460...46,383,680
Ensembl chr16:46,352,467...46,383,657 		JBrowse link
G Pdlim4 PDZ and LIM domain 4 part_of ISO
IEA
IBA		 (PMID:10826496)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:10826496 GO_REF:0000033 GO_REF:0000107 NCBI chr10:38,198,686...38,212,935
Ensembl chr10:38,198,689...38,212,938 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275 		JBrowse link
G Pdlim7 PDZ and LIM domain 7 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:9,124,565...9,139,814
Ensembl chr17:9,124,649...9,139,811 		JBrowse link
G Prickle4 prickle planar cell polarity protein 4 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:13,297,494...13,305,635
Ensembl chr 9:13,297,758...13,305,630 		JBrowse link
G Rac3 Rac family small GTPase 3 part_of ISO (PMID:16525025) RGD PMID:16525025 NCBI chr10:106,002,808...106,005,243
Ensembl chr10:105,993,087...106,005,260 		JBrowse link
G Smtn smoothelin part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:78,398,595...78,420,908
Ensembl chr14:78,397,778...78,420,886 		JBrowse link
G Smtnl1 smoothelin-like 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:69,889,010...69,901,096
Ensembl chr 3:69,889,010...69,901,079 		JBrowse link
G Smtnl2 smoothelin-like 2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:57,008,322...57,029,505
Ensembl chr10:57,008,327...57,029,505 		JBrowse link
G Specc1 sperm antigen with calponin homology and coiled-coil domains 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:46,638,947...46,912,989
Ensembl chr10:46,638,809...46,912,802 		JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like part_of IBA
ISO		 GO_REF:0000033
(PMID:21703590)		 GO_Central
RGD		 PMID:21703590 GO_REF:0000033 NCBI chr20:13,337,983...13,443,665
Ensembl chr20:13,339,692...13,443,665 		JBrowse link
G Tmsb15b2 thymosin beta 15B2 part_of ISO (PMID:19233202) RGD PMID:19233202 NCBI chr  X:100,298,705...100,300,820
Ensembl chr  X:100,298,514...100,300,886 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20813
    cellular anatomical entity 20576
      supramolecular complex 1396
        supramolecular polymer 1038
          supramolecular fiber 1031
            polymeric cytoskeletal fiber 772
              actin filament 136
                actin filament branch point 1
                actin filament of cell cortex of cell tip 0
                actomyosin contractile ring actin filament 0
                filamentous actin 37
Path 2
Term Annotations click to browse term
  cellular_component 20813
    cellular anatomical entity 20576
      organelle 14001
        non-membrane-bounded organelle 5255
          intracellular non-membrane-bounded organelle 5255
            cytoskeleton 2367
              actin cytoskeleton 542
                actin filament 136
                  actin filament branch point 1
                  actin filament of cell cortex of cell tip 0
                  actomyosin contractile ring actin filament 0
                  filamentous actin 37
paths to the root