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ONTOLOGY REPORT - ANNOTATIONS


Term:neurofilament
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Accession:GO:0005883 term browser browse the term
Definition:A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter.
Synonyms:exact_synonym: type IV intermediate filament
 xref: NIF_Subcellular:sao1316272517;   Wikipedia:Neurofilament


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neurofilament term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn11 claudin 11 located_in ISO
IEA
(PMID:30734065)
GO_REF:0000107
RGD
Ensembl
PMID:30734065 GO_REF:0000107 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Dlgap2 DLG associated protein 2 located_in NAS PMID:9286858 UniProt PMID:9286858 RGD:8554678 NCBI chr16:79,872,238...80,596,977
Ensembl chr16:79,872,323...79,973,877
JBrowse link
G Dmd dystrophin IDA RGD PMID:11326752 RGD:12880030 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A colocalizes_with ISO UniProtKB:P12036 (PMID:24327345) RGD PMID:24327345 NCBI chr11:34,858,339...34,958,733
Ensembl chr11:34,865,532...34,956,536
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha located_in IEA
ISO
GO_REF:0000107
(MGI:1336062|PMID:10221457)
Ensembl
RGD
PMID:10221457 GO_REF:0000107 MGI:1336062 NCBI chr 1:266,782,835...266,794,389
Ensembl chr 1:266,781,617...266,794,431
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 located_in ISO (MGI:3762243|PMID:17727637) RGD PMID:17727637 MGI:3762243 NCBI chr 5:152,964,294...152,987,286
Ensembl chr 5:152,966,591...152,987,211
JBrowse link
G Nefh neurofilament heavy chain located_in IEA
ISO
GO_REF:0000002
(MGI:1336062|PMID:10221457), (MGI:3046159|PMID:15248193), (MGI:4439458|PMID:20176735)
(PMID:8634266)
InterPro
RGD
PMID:8634266 PMID:10221457 PMID:15248193 PMID:20176735 GO_REF:0000002 MGI:1336062 MGI:3046159 MGI:4439458 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nefl neurofilament light chain located_in IDA
ISO
(MGI:1336062|PMID:10221457), (MGI:3052885|PMID:15242779), (MGI:81460|PMID:8821035)
(PMID:3920075), (PMID:8634266)
(PMID:15857389)
RGD PMID:3920075 PMID:8634266 PMID:8821035 PMID:10221457 PMID:15242779 PMID:15857389, PMID:7721944 MGI:1336062 MGI:3052885 MGI:81460, RGD:9743935 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nefm neurofilament medium chain located_in IDA
ISO
IEA
(MGI:1336062|PMID:10221457), (MGI:1344237|PMID:10482234), (MGI:2675767|PMID:12971893), (MGI:3046159|PMID:15248193)
GO_REF:0000002
RGD
InterPro
PMID:10221457 PMID:10482234 PMID:12971893 PMID:15248193, PMID:7721944 GO_REF:0000002 MGI:1336062 MGI:1344237 MGI:2675767 MGI:3046159, RGD:9743935 NCBI chr15:44,855,307...44,860,604
Ensembl chr15:44,855,310...44,860,604
JBrowse link
G Nrp1 neuropilin 1 located_in ISO (MGI:3578029|PMID:15814794) RGD PMID:15814794 MGI:3578029 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Pcp4 Purkinje cell protein 4 IDA RGD PMID:10556647 RGD:9850249 NCBI chr11:36,851,035...36,912,272
Ensembl chr11:36,851,038...36,912,229
JBrowse link
G Prph peripherin located_in ISO (MGI:1336062|PMID:10221457) RGD PMID:10221457 MGI:1336062 NCBI chr 7:140,742,406...140,746,197
Ensembl chr 7:140,742,418...140,746,197
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 colocalizes_with
part_of
ISS
ISO
GO_REF:0000024
(MGI:5306573|PMID:19299912)
BHF-UCL
RGD
PMID:19299912 GO_REF:0000024 MGI:5306573 NCBI chr 1:217,149,156...217,593,950
Ensembl chr 1:217,151,166...217,592,763
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20138
    cellular anatomical entity 19840
      cytoplasm 11424
        neurofilament 13
Path 2
Term Annotations click to browse term
  cellular_component 20138
    cellular anatomical entity 19840
      organelle 13143
        intracellular organelle 12795
          intracellular non-membrane-bounded organelle 4913
            cytoskeleton 2178
              intermediate filament cytoskeleton 199
                intermediate filament 157
                  neurofilament 13
paths to the root