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ONTOLOGY REPORT - ANNOTATIONS


Term:troponin complex
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Accession:GO:0005861 term browser browse the term
Definition:A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction.


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troponin complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07013776.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:256,154,141...256,154,584 JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type ISO
IBA
(PMID:10850966), (PMID:12093807)
PMID:21873635
RGD PMID:10850966, PMID:12093807, PMID:21873635 RGD:13792537 NCBI chr16:7,292,207...7,295,238
Ensembl chr16:7,292,096...7,295,465
JBrowse link
G Tnnc2 troponin C2, fast skeletal type ISO
IBA
(PMID:17194691)
PMID:21873635
RGD PMID:17194691, PMID:21873635 RGD:13792537 NCBI chr 3:161,243,607...161,246,335
Ensembl chr 3:161,243,587...161,246,351
JBrowse link
G Tnni1 troponin I1, slow skeletal type IDA
IEA
GO_REF:0000002 InterPro PMID:16192301 GO_REF:0000002, RGD:1599030 NCBI chr13:52,624,856...52,637,297
Ensembl chr13:52,624,878...52,637,297
JBrowse link
G Tnni2 troponin I2, fast skeletal type IDA
ISO
IEA
(PMID:17194691)
GO_REF:0000002
RGD
InterPro
PMID:17194691, PMID:16192301 GO_REF:0000002, RGD:1599030 NCBI chr 1:215,609,110...215,611,652
Ensembl chr 1:215,609,036...215,611,658
JBrowse link
G Tnni3 troponin I3, cardiac type TAS
ISO
(PMID:10806205), (PMID:10850966), (PMID:12093807), (PMID:7957210) RGD PMID:7957210, PMID:10806205, PMID:10850966, PMID:12093807, PMID:1886137 RGD:730167 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
G Tnnt1 troponin T1, slow skeletal type IDA
IBA
ISO
PMID:21873635
(PMID:15665378), (PMID:18032382)
RGD PMID:15665378, PMID:18032382, PMID:16192301, PMID:21873635, PMID:15788488 RGD:1599030, RGD:13792537, RGD:1599482 NCBI chr 1:72,889,270...72,899,629
Ensembl chr 1:72,889,270...72,899,659
JBrowse link
G Tnnt2 troponin T2, cardiac type IDA
IBA
ISO
IEA
PMID:21873635
(PMID:12093807), (PMID:12186860), (PMID:2530435)
(MGI:MGI:2675179|PMID:12832403)
GO_REF:0000002
RGD
InterPro
PMID:2530435, PMID:12093807, PMID:12186860, PMID:12832403, PMID:12501194, PMID:21873635 GO_REF:0000002, MGI:MGI:2675179, RGD:1580426, RGD:13792537 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
G Tnnt3 troponin T3, fast skeletal type TAS
IBA
IEA
ISO
IDA
PMID:21873635
GO_REF:0000107
(PMID:17194691), (PMID:8987992), (PMID:9724539)
GO_REF:0000002
Ensembl
RGD
InterPro
PMID:8987992, PMID:9724539, PMID:17194691, PMID:11940518, PMID:21873635, PMID:16192301 GO_REF:0000002, GO_REF:0000107, RGD:1299083, RGD:13792537, RGD:1599030 NCBI chr 1:215,666,628...215,683,628
Ensembl chr 1:215,666,628...215,683,628
JBrowse link
cardiac Troponin complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnnc1 troponin C1, slow skeletal and cardiac type ISO (PMID:25771144) RGD PMID:25771144 NCBI chr16:7,292,207...7,295,238
Ensembl chr16:7,292,096...7,295,465
JBrowse link
G Tnni3 troponin I3, cardiac type ISO (PMID:25771144) RGD PMID:25771144 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
G Tnnt2 troponin T2, cardiac type ISO (PMID:25771144) RGD PMID:25771144 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      troponin complex 9
        cardiac Troponin complex 3
Path 2
Term Annotations click to browse term
  cellular_component 20609
    cellular anatomical entity 20358
      organelle 13258
        non-membrane-bounded organelle 5183
          intracellular non-membrane-bounded organelle 5172
            contractile fiber 247
              myofibril 237
                myofilament 23
                  striated muscle thin filament 20
                    troponin complex 9
                      cardiac Troponin complex 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.